{"id":"https://openalex.org/W2407516205","doi":"https://doi.org/10.1042/bj2700605","title":"5\u2032-S-(2-aminoethyl)-N6-(4-nitrobenzyl)-5\u2032-thioadenosine (SAENTA), a novel ligand with high affinity for polypeptides associated with nucleoside transport. Partial purification of the nitrobenzylthioinosine-binding protein of pig erythrocytes by affinity chromatography","display_name":"5\u2032-S-(2-aminoethyl)-N6-(4-nitrobenzyl)-5\u2032-thioadenosine (SAENTA), a novel ligand with high affinity for polypeptides associated with nucleoside transport. Partial purification of the nitrobenzylthioinosine-binding protein of pig erythrocytes by affinity chromatography","publication_year":1990,"publication_date":"1990-09-15","ids":{"openalex":"https://openalex.org/W2407516205","doi":"https://doi.org/10.1042/bj2700605","mag":"2407516205","pmid":"https://pubmed.ncbi.nlm.nih.gov/2241896","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1131775"},"language":"en","primary_location":{"id":"doi:10.1042/bj2700605","doi":"https://doi.org/10.1042/bj2700605","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj2700605","pdf_url":"https://portlandpress.com/biochemj/article-pdf/270/3/605/601513/bj2700605.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://portlandpress.com/biochemj/article-pdf/270/3/605/601513/bj2700605.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083296529","display_name":"Francisca R. Agbanyo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"F R Agbanyo","raw_affiliation_strings":["McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001587989","display_name":"D Vijayalakshmi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"D Vijayalakshmi","raw_affiliation_strings":["McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001226730","display_name":"James D. Craik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"J D Craik","raw_affiliation_strings":["McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112093339","display_name":"W P Gati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"W P Gati","raw_affiliation_strings":["Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059397401","display_name":"David P. McAdam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"D P McAdam","raw_affiliation_strings":["Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043932479","display_name":"Jun\u2010Ichi Asakura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"J Asakura","raw_affiliation_strings":["Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108932181","display_name":"M. J. ROBINS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100005738","display_name":"Brigham Young University","ror":"https://ror.org/047rhhm47","country_code":"US","type":"education","lineage":["https://openalex.org/I100005738"]},{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"M J Robins","raw_affiliation_strings":["Department of Chemistry, Brigham Young University, Provo, UT 84602, U.S.A","Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Brigham Young University, Provo, UT 84602, U.S.A","institution_ids":["https://openalex.org/I100005738"]},{"raw_affiliation_string":"Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110409988","display_name":"A. R. P. Paterson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"A R P Paterson","raw_affiliation_strings":["Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113882809","display_name":"Carol E. Cass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"C E Cass","raw_affiliation_strings":["Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]},{"raw_affiliation_string":"McEachern Laboratory, University of Alberta, Edmonton, Alberta, Canada, T6G 2H7","institution_ids":["https://openalex.org/I154425047"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5001587989"],"corresponding_institution_ids":["https://openalex.org/I154425047"],"apc_list":null,"apc_paid":null,"fwci":0.5702,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.65623838,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"270","issue":"3","first_page":"605","last_page":"614"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.8192999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.8192999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11193","display_name":"Adenosine and Purinergic Signaling","score":0.08219999819993973,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.025100000202655792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitrobenzylthioinosine","display_name":"nitrobenzylthioinosine","score":0.875},{"id":"https://openalex.org/keywords/nucleoside-transport","display_name":"nucleoside transport","score":0.7549999952316284},{"id":"https://openalex.org/keywords/equilibrative-nucleoside-transporter","display_name":"equilibrative nucleoside transporter","score":0.9459999799728394},{"id":"https://openalex.org/keywords/affinity-chromatography","display_name":"affinity chromatography","score":0.6579999923706055},{"id":"https://openalex.org/keywords/pig-erythrocytes","display_name":"pig erythrocytes","score":0.8199999928474426},{"id":"https://openalex.org/keywords/affinity-ligands","display_name":"affinity ligands","score":0.4659999907016754}],"concepts":[{"id":"https://openalex.org/C2776543447","wikidata":"https://www.wikidata.org/wiki/Q28734","display_name":"Nucleoside","level":2,"score":0.7597815990447998},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.6720830798149109},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.597333550453186},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3341929614543915},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28565889596939087},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.12408271431922913}],"mesh":[{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000345","descriptor_name":"Affinity Labels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004910","descriptor_name":"Erythrocyte Membrane","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005960","descriptor_name":"Glucosides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008024","descriptor_name":"Ligands","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008970","descriptor_name":"Molecular Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009705","descriptor_name":"Nucleosides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013868","descriptor_name":"Thioinosine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D013868","descriptor_name":"Thioinosine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013872","descriptor_name":"Thionucleosides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D033703","descriptor_name":"Nucleoside Transport Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1042/bj2700605","doi":"https://doi.org/10.1042/bj2700605","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj2700605","pdf_url":"https://portlandpress.com/biochemj/article-pdf/270/3/605/601513/bj2700605.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:4408095","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1131775","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1131775","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1131775","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochem J","raw_type":"Text"},{"id":"pmid:2241896","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2241896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Biochemical journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1042/bj2700605","doi":"https://doi.org/10.1042/bj2700605","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj2700605","pdf_url":"https://portlandpress.com/biochemj/article-pdf/270/3/605/601513/bj2700605.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321589","display_name":"Fondation pour la Recherche M\u00e9dicale","ror":"https://ror.org/04w6kn183"},{"id":"https://openalex.org/F4320324195","display_name":"Medical Research Council Canada","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2407516205.pdf","grobid_xml":"https://content.openalex.org/works/W2407516205.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W76315661","https://openalex.org/W92181112","https://openalex.org/W143707251","https://openalex.org/W206819481","https://openalex.org/W291941011","https://openalex.org/W1264549095","https://openalex.org/W1481157419","https://openalex.org/W1530387751","https://openalex.org/W1536116198","https://openalex.org/W1551743456","https://openalex.org/W1751811227","https://openalex.org/W1775749144","https://openalex.org/W1966332025","https://openalex.org/W1976365732","https://openalex.org/W1984367265","https://openalex.org/W1993722361","https://openalex.org/W2005285041","https://openalex.org/W2018289835","https://openalex.org/W2024001544","https://openalex.org/W2025678921","https://openalex.org/W2035863360","https://openalex.org/W2042784970","https://openalex.org/W2044878731","https://openalex.org/W2058421275","https://openalex.org/W2069959354","https://openalex.org/W2070776215","https://openalex.org/W2073808679","https://openalex.org/W2078477493","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2102131116","https://openalex.org/W2120267286","https://openalex.org/W2134315526","https://openalex.org/W2203879728","https://openalex.org/W2246661972","https://openalex.org/W2341550333","https://openalex.org/W2341663147","https://openalex.org/W2394625437","https://openalex.org/W2408491101","https://openalex.org/W2410078685","https://openalex.org/W2473567778","https://openalex.org/W2487006092","https://openalex.org/W4232534952"],"related_works":["https://openalex.org/W2064107454","https://openalex.org/W1530387751","https://openalex.org/W1999307838","https://openalex.org/W1551743456","https://openalex.org/W2203879728","https://openalex.org/W2342351464","https://openalex.org/W2035863360","https://openalex.org/W2042399844","https://openalex.org/W2042784970","https://openalex.org/W1967026814"],"abstract_inverted_index":{"Derivatives":[0],"of":[1,11,18,21,38,57,106,122,126,142,146,186,196,203,219],"N6-(4-aminobenzyl)adenosine":[2],"(substituted":[3],"at":[4],"the":[5,71,113,123,139,147,187],"aminobenzyl":[6],"group)":[7],"and":[8,33,86],"5'-linked":[9],"derivatives":[10],"N6-(4-nitrobenzyl)adenosine":[12],"(NBAdo)":[13],"were":[14,30,79,109,118,159],"evaluated":[15],"as":[16,95,120],"inhibitors":[17,29],"site-specific":[19],"binding":[20],"[3H]nitrobenzylthioinosine":[22],"(NBMPR)":[23],"to":[24,43,49,88],"pig":[25,62,76,127,143],"erythrocyte":[26,77],"membranes.":[27],"Potent":[28],"SAENTA":[31,40,234],"[5'-S-(2-aminoethyl)-N6-(4-nitrobenzyl)-5'-thioadenosine]":[32],"acetyl-SAENTA":[34],"(the":[35],"2-acetamidoethyl":[36],"derivative":[37],"SAENTA).":[39],"was":[41,152,190],"coupled":[42],"derivatized":[44],"agarose-gel":[45],"beads":[46],"(Affi-Gel":[47],"10)":[48],"form":[50],"an":[51,102],"affinity":[52,114,228],"matrix":[53],"for":[54],"chromatographic":[55],"purification":[56],"NBMPR-binding":[58,140],"polypeptides,":[59],"which":[60],"in":[61],"erythrocytes":[63,128],"are":[64,68],"part":[65],"of,":[66],"or":[67,171,181],"associated":[69],"with,":[70],"equilibrative":[72],"nucleoside":[73,124],"transporter.":[74],"When":[75],"membranes":[78,199],"solubilized":[80],"with":[81,101,131,168,174,208],"octyl":[82],"glucoside":[83],"(n-octyl":[84],"beta-D-glucopyranoside)":[85],"applied":[87],"SAENTA-Affi-Gel":[89],"10":[90],"(SAENTA-AG10),":[91],"polypeptides":[92,117,149,158,189],"that":[93,137,216],"migrated":[94],"a":[96,132,193,201],"broad":[97],"band":[98],"on":[99],"SDS/PAGE":[100],"apparent":[103],"molecular":[104],"mass":[105],"58-60":[107],"kDa":[108],"selectively":[110],"retained":[111],"by":[112,129,150,154,163,172,192,206,227],"gel.":[115],"These":[116,213],"identified":[119],"components":[121,218],"transporter":[125],"reactivity":[130],"monoclonal":[133],"antibody":[134],"(mAb":[135],"11C4)":[136],"recognizes":[138],"protein":[141],"erythrocytes.":[144],"Retention":[145],"immunoreactive":[148,157,188],"SAENTA-AG10":[151,162],"blocked":[153],"NBAdo.":[155,212],"The":[156],"released":[160],"from":[161],"elution":[164,173,207],"under":[165],"denaturing":[166],"conditions":[167],"1%":[169],"SDS":[170],"detergent":[175,209],"solutions":[176,210],"containing":[177,211],"competitive":[178],"ligands":[179],"(NBAdo":[180],"NBMPR).":[182],"A":[183],"72-fold":[184],"enrichment":[185],"achieved":[191],"single":[194],"passage":[195],"solubilized,":[197],"protein-depleted":[198],"through":[200],"column":[202],"SAENTA-AG10,":[204],"followed":[205],"results":[214],"demonstrate":[215],"polypeptide":[217],"NBMPR-sensitive":[220],"nucleoside-transport":[221],"systems":[222],"may":[223],"be":[224],"partly":[225],"purified":[226],"chromatography":[229],"using":[230],"gel":[231],"media":[232],"bearing":[233],"groups.":[235]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}