{"id":"https://openalex.org/W240648977","doi":"https://doi.org/10.1023/a:1007468521927","title":"Cellular characteristics of epithelial cell lines from juvenile rat liver: selective induction of glutamine synthetase by dexamethasone","display_name":"Cellular characteristics of epithelial cell lines from juvenile rat liver: selective induction of glutamine synthetase by dexamethasone","publication_year":1998,"publication_date":"1998-02-01","ids":{"openalex":"https://openalex.org/W240648977","doi":"https://doi.org/10.1023/a:1007468521927","mag":"240648977","pmid":"https://pubmed.ncbi.nlm.nih.gov/9538945"},"language":"en","primary_location":{"id":"doi:10.1023/a:1007468521927","doi":"https://doi.org/10.1023/a:1007468521927","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1007468521927","pdf_url":null,"source":{"id":"https://openalex.org/S31257671","display_name":"Cell Biology and Toxicology","issn_l":"0742-2091","issn":["0742-2091","1573-6822"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Biology and Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112090999","display_name":"Rolf Gebhardt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8087733","display_name":"University of T\u00fcbingen","ror":"https://ror.org/03a1kwz48","country_code":"DE","type":"education","lineage":["https://openalex.org/I8087733"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R. Gebhardt","raw_affiliation_strings":["Physiologisch-Chemisches Institut der Universit\u00e4t, T\u00fcbingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physiologisch-Chemisches Institut der Universit\u00e4t, T\u00fcbingen, Germany","institution_ids":["https://openalex.org/I8087733"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081604752","display_name":"W. Schrode","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. Schrode","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5075930077","display_name":"Iris Eisenmann-Tappe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I. Eisenmann-Tappe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":0.4946,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.66858384,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"14","issue":"1","first_page":"55","last_page":"67"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9394999742507935,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.9394999742507935,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutamine-synthetase","display_name":"glutamine synthetase","score":0.8429999947547913},{"id":"https://openalex.org/keywords/dexamethasone","display_name":"dexamethasone","score":0.9330000281333923},{"id":"https://openalex.org/keywords/bile-duct-epithelial-cells","display_name":"bile duct epithelial cells","score":0.8190000057220459},{"id":"https://openalex.org/keywords/hepatocytes","display_name":"hepatocytes","score":0.8220000267028809},{"id":"https://openalex.org/keywords/cell-of-origin","display_name":"cell of origin","score":0.4959999918937683},{"id":"https://openalex.org/keywords/vimentin","display_name":"vimentin","score":0.6690000295639038},{"id":"https://openalex.org/keywords/cytokeratin-19","display_name":"cytokeratin 19","score":0.996999979019165},{"id":"https://openalex.org/keywords/amino-acid-absorption","display_name":"amino acid uptake","score":0.8610000014305115},{"id":"https://openalex.org/keywords/glutamine","display_name":"glutamine","score":0.6349999904632568},{"id":"https://openalex.org/keywords/newborn-calf-serum","display_name":"newborn calf serum","score":0.6710000038146973},{"id":"https://openalex.org/keywords/cell-phenotype","display_name":"cell phenotype","score":0.3580000102519989}],"concepts":[{"id":"https://openalex.org/C2779289688","wikidata":"https://www.wikidata.org/wiki/Q418306","display_name":"Glutamine synthetase","level":4,"score":0.7476781606674194},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.6853085160255432},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6676517128944397},{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.6344742774963379},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.5869980454444885},{"id":"https://openalex.org/C147447768","wikidata":"https://www.wikidata.org/wiki/Q411624","display_name":"Vimentin","level":3,"score":0.5307756662368774},{"id":"https://openalex.org/C2780186670","wikidata":"https://www.wikidata.org/wiki/Q5104283","display_name":"Cholangiocyte","level":2,"score":0.5162160992622375},{"id":"https://openalex.org/C2779012181","wikidata":"https://www.wikidata.org/wiki/Q2750567","display_name":"Cytokeratin","level":3,"score":0.5047608613967896},{"id":"https://openalex.org/C2778024521","wikidata":"https://www.wikidata.org/wiki/Q55639806","display_name":"Basal (medicine)","level":3,"score":0.46936753392219543},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.45876118540763855},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.4518931210041046},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4346907138824463},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.41717129945755005},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4073446989059448},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.40511152148246765},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3277202248573303},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24551013112068176},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.2200814187526703},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15373939275741577},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.1300765573978424},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07928827404975891},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.05785360932350159},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003907","descriptor_name":"Dexamethasone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004790","descriptor_name":"Enzyme Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D005974","descriptor_name":"Glutamate-Ammonia Ligase","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1023/a:1007468521927","doi":"https://doi.org/10.1023/a:1007468521927","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1007468521927","pdf_url":null,"source":{"id":"https://openalex.org/S31257671","display_name":"Cell Biology and Toxicology","issn_l":"0742-2091","issn":["0742-2091","1573-6822"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Biology and Toxicology","raw_type":"journal-article"},{"id":"pmid:9538945","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9538945","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell biology and toxicology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W306340179","https://openalex.org/W614317403","https://openalex.org/W1504552010","https://openalex.org/W1545285436","https://openalex.org/W1568038050","https://openalex.org/W1603255584","https://openalex.org/W1633473664","https://openalex.org/W1775749144","https://openalex.org/W1785497696","https://openalex.org/W1965950337","https://openalex.org/W1966569385","https://openalex.org/W1972487225","https://openalex.org/W1972714501","https://openalex.org/W1973012145","https://openalex.org/W1973793997","https://openalex.org/W1973997143","https://openalex.org/W1975273361","https://openalex.org/W1977665282","https://openalex.org/W1985422398","https://openalex.org/W1987966242","https://openalex.org/W1991501430","https://openalex.org/W1999867501","https://openalex.org/W2002467411","https://openalex.org/W2007263719","https://openalex.org/W2007412548","https://openalex.org/W2011100121","https://openalex.org/W2013916453","https://openalex.org/W2015064104","https://openalex.org/W2016955856","https://openalex.org/W2021816068","https://openalex.org/W2025424238","https://openalex.org/W2028161539","https://openalex.org/W2031896298","https://openalex.org/W2034347966","https://openalex.org/W2037784945","https://openalex.org/W2043404668","https://openalex.org/W2044839358","https://openalex.org/W2046034941","https://openalex.org/W2046442503","https://openalex.org/W2049272715","https://openalex.org/W2053470391","https://openalex.org/W2055849021","https://openalex.org/W2060794300","https://openalex.org/W2069025377","https://openalex.org/W2071180078","https://openalex.org/W2075573504","https://openalex.org/W2076013350","https://openalex.org/W2076036308","https://openalex.org/W2077253679","https://openalex.org/W2086658389","https://openalex.org/W2098781130","https://openalex.org/W2124709411","https://openalex.org/W2127544504","https://openalex.org/W2142133226","https://openalex.org/W2170314164","https://openalex.org/W2188207096","https://openalex.org/W2322683381","https://openalex.org/W2410353635","https://openalex.org/W2417465380","https://openalex.org/W2420415369","https://openalex.org/W2424767606","https://openalex.org/W2614923698","https://openalex.org/W2743361728"],"related_works":["https://openalex.org/W306340179","https://openalex.org/W1965892920","https://openalex.org/W1504552010","https://openalex.org/W1987966242","https://openalex.org/W2420415369","https://openalex.org/W2322683381","https://openalex.org/W2515815255","https://openalex.org/W2033192068","https://openalex.org/W1973264472","https://openalex.org/W2013916453"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}