{"id":"https://openalex.org/W2405939607","doi":"https://doi.org/10.1007/s13530-016-0261-5","title":"Electrolyzed-reduced water mitigates amyloid beta toxicity via DAF-16 in C. elegans","display_name":"Electrolyzed-reduced water mitigates amyloid beta toxicity via DAF-16 in C. elegans","publication_year":2016,"publication_date":"2016-03-01","ids":{"openalex":"https://openalex.org/W2405939607","doi":"https://doi.org/10.1007/s13530-016-0261-5","mag":"2405939607"},"language":"en","primary_location":{"id":"doi:10.1007/s13530-016-0261-5","doi":"https://doi.org/10.1007/s13530-016-0261-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13530-016-0261-5","pdf_url":null,"source":{"id":"https://openalex.org/S2764590744","display_name":"Toxicology and Environmental Health Sciences","issn_l":"2005-9752","issn":["2005-9752","2233-7784"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology and Environmental Health Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Jin-Sun Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24541011","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10","country_code":"KR","type":"education","lineage":["https://openalex.org/I24541011"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jin-Sun Lee","raw_affiliation_strings":["Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, 31539, Korea","Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, 31539, Korea","institution_ids":["https://openalex.org/I24541011"]},{"raw_affiliation_string":"Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, Korea","institution_ids":["https://openalex.org/I24541011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078360569","display_name":"Seul-Ki Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24541011","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10","country_code":"KR","type":"education","lineage":["https://openalex.org/I24541011"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seul-Ki Park","raw_affiliation_strings":["Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, 31539, Korea","Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, 31539, Korea","institution_ids":["https://openalex.org/I24541011"]},{"raw_affiliation_string":"Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, Korea","institution_ids":["https://openalex.org/I24541011"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100676686","display_name":"Sang-Kyu Park","orcid":"https://orcid.org/0000-0001-7697-1434","observed_orcids":["https://orcid.org/0000-0001-7697-1434"]},"institutions":[{"id":"https://openalex.org/I24541011","display_name":"Soonchunhyang University","ror":"https://ror.org/03qjsrb10","country_code":"KR","type":"education","lineage":["https://openalex.org/I24541011"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Sang-Kyu Park","raw_affiliation_strings":["Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, 31539, Korea","Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, 31539, Korea","institution_ids":["https://openalex.org/I24541011"]},{"raw_affiliation_string":"Department of Medical Biotechnology, College of Medical Science, Soonchunhyang University, Asan, Korea","institution_ids":["https://openalex.org/I24541011"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100676686"],"corresponding_institution_ids":["https://openalex.org/I24541011"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":0.2283,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.59924022,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"8","issue":"1","first_page":"56","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.9726999998092651,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13775","display_name":"Hydrogen's biological and therapeutic effects","score":0.012900000438094139,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10676","display_name":"Genetics, Aging, and Longevity in Model Organisms","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1302","display_name":"Aging"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electrolyzed-reduced-water","display_name":"electrolyzed reduced water","score":0.996999979019165},{"id":"https://openalex.org/keywords/amyloid-beta-toxicity","display_name":"amyloid-beta toxicity","score":0.9049999713897705},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.906000018119812},{"id":"https://openalex.org/keywords/daf-16","display_name":"DAF-16","score":0.9950000047683716},{"id":"https://openalex.org/keywords/foxo-transcription-factors","display_name":"FOXO transcription factors","score":0.984000027179718},{"id":"https://openalex.org/keywords/insulin-igf-1-signaling","display_name":"insulin/IGF-1 signaling","score":0.9190000295639038},{"id":"https://openalex.org/keywords/caenorhabditis-elegans","display_name":"Caenorhabditis elegans","score":0.9279999732971191},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.6480000019073486},{"id":"https://openalex.org/keywords/lifespan-extension","display_name":"lifespan extension","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.7902114391326904},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.6069899797439575},{"id":"https://openalex.org/C2776156579","wikidata":"https://www.wikidata.org/wiki/Q417667","display_name":"Amyloid beta","level":3,"score":0.6034565567970276},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.5140498876571655},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.48743823170661926},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.4544844627380371},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.370053768157959},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.338503897190094},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3219265639781952},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29260122776031494},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27000609040260315},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2661629915237427},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s13530-016-0261-5","doi":"https://doi.org/10.1007/s13530-016-0261-5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s13530-016-0261-5","pdf_url":null,"source":{"id":"https://openalex.org/S2764590744","display_name":"Toxicology and Environmental Health Sciences","issn_l":"2005-9752","issn":["2005-9752","2233-7784"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Toxicology and Environmental Health Sciences","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W191643116","https://openalex.org/W1812816875","https://openalex.org/W1974323467","https://openalex.org/W1975595547","https://openalex.org/W1981964968","https://openalex.org/W2002559713","https://openalex.org/W2002656723","https://openalex.org/W2038492783","https://openalex.org/W2043829280","https://openalex.org/W2055081051","https://openalex.org/W2057043575","https://openalex.org/W2058268504","https://openalex.org/W2061120469","https://openalex.org/W2062629127","https://openalex.org/W2081881251","https://openalex.org/W2083767129","https://openalex.org/W2109502717","https://openalex.org/W2113007696","https://openalex.org/W2121963977","https://openalex.org/W2133740677","https://openalex.org/W2155043532","https://openalex.org/W2160989788","https://openalex.org/W2164404095","https://openalex.org/W2168628608"],"related_works":["https://openalex.org/W3214315589","https://openalex.org/W2581475444","https://openalex.org/W4231026226","https://openalex.org/W2912583135","https://openalex.org/W7130694914","https://openalex.org/W2498310467","https://openalex.org/W7117138275","https://openalex.org/W1974323467","https://openalex.org/W2298853359","https://openalex.org/W3215202495"],"abstract_inverted_index":null,"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}