{"id":"https://openalex.org/W2404043537","doi":null,"title":"[Increased tRNA concentration in yeast containing mutant termination translation factors eRF1 and eRF3].","display_name":"[Increased tRNA concentration in yeast containing mutant termination translation factors eRF1 and eRF3].","publication_year":2006,"publication_date":"2006-07-01","ids":{"openalex":"https://openalex.org/W2404043537","mag":"2404043537","pmid":"https://pubmed.ncbi.nlm.nih.gov/16913231"},"language":"ru","primary_location":{"id":"pmid:16913231","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16913231","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molekuliarnaia biologiia","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070747987","display_name":"Galina A. Zhouravleva","orcid":"https://orcid.org/0000-0002-3013-4662","observed_orcids":["https://orcid.org/0000-0002-3013-4662"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G A Zhuravleva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035898494","display_name":"Svetlana E. Moskalenko","orcid":"https://orcid.org/0000-0003-0419-0000","observed_orcids":["https://orcid.org/0000-0003-0419-0000"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S E Moskalenko","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052613657","display_name":"Shabel'skaia Sv","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S V Shabel'skaia","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109107277","display_name":"M. Philippe","orcid":"https://orcid.org/0000-0003-0762-4134","observed_orcids":["https://orcid.org/0000-0003-0762-4134"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Philippe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5037716535","display_name":"Sergey Georgievich Inge-Vechtomov","orcid":"https://orcid.org/0000-0002-2832-6825","observed_orcids":["https://orcid.org/0000-0002-2832-6825"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S G Inge-Vechtomov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3367,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.49124547,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"40","issue":"4","first_page":"724","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/translation-termination-factor","display_name":"translation termination factor","score":0.8790000081062317},{"id":"https://openalex.org/keywords/erf1","display_name":"eRF1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/erf3","display_name":"eRF3","score":1.0},{"id":"https://openalex.org/keywords/sup45","display_name":"SUP45","score":0.9789999723434448},{"id":"https://openalex.org/keywords/sup35","display_name":"Sup35","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nonsense-mutation","display_name":"nonsense mutation","score":0.8889999985694885},{"id":"https://openalex.org/keywords/suppressor-trna","display_name":"suppressor tRNA","score":0.9190000295639038},{"id":"https://openalex.org/keywords/yeast","display_name":"yeast","score":0.4189999997615814},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9100000262260437},{"id":"https://openalex.org/keywords/translation-termination","display_name":"translation termination","score":0.4410000145435333}],"concepts":[{"id":"https://openalex.org/C153957851","wikidata":"https://www.wikidata.org/wiki/Q201448","display_name":"Transfer RNA","level":4,"score":0.8664567470550537},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.6650089025497437},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.6581431031227112},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6404520273208618},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6187171936035156},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.5914884209632874},{"id":"https://openalex.org/C62923972","wikidata":"https://www.wikidata.org/wiki/Q600499","display_name":"Nonsense","level":3,"score":0.5355690717697144},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.49222055077552795},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47959887981414795},{"id":"https://openalex.org/C96777560","wikidata":"https://www.wikidata.org/wiki/Q518638","display_name":"Nonsense mutation","level":5,"score":0.45616158843040466},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.43941327929496765},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.40060484409332275},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.2945713698863983},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.11723455786705017},{"id":"https://openalex.org/C75563809","wikidata":"https://www.wikidata.org/wiki/Q2656896","display_name":"Missense mutation","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010454","descriptor_name":"Peptide Termination Factors","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010454","descriptor_name":"Peptide Termination Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011328","descriptor_name":"Prions","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011328","descriptor_name":"Prions","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012331","descriptor_name":"RNA, Fungal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012331","descriptor_name":"RNA, Fungal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012343","descriptor_name":"RNA, Transfer","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018388","descriptor_name":"Codon, Terminator","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018389","descriptor_name":"Codon, Nonsense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":1,"locations":[{"id":"pmid:16913231","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16913231","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molekuliarnaia biologiia","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2016370919","https://openalex.org/W2971015032","https://openalex.org/W2108003575","https://openalex.org/W2412386991","https://openalex.org/W2057963139","https://openalex.org/W1741202577","https://openalex.org/W273369469","https://openalex.org/W4200315221","https://openalex.org/W2091940323","https://openalex.org/W2041297451"],"abstract_inverted_index":{"Earlier":[0],"we":[1],"have":[2,35,63],"characterized":[3],"strains":[4],"bearing":[5],"mutations":[6,79],"in":[7,68,83],"essential":[8,97],"genes":[9,31,98],"SUP45":[10,32,99],"and":[11,22,33,48,56,60,100],"SUP35":[12,34,101],"of":[13,41,70,76,86,94],"yeast":[14],"S.":[15],"cerevisiae,":[16],"encoding":[17],"translation":[18],"termination":[19],"factors":[20],"eRF1":[21],"eRF3":[23],"respectively.":[24],"In":[25],"the":[26,77],"present":[27],"work":[28],"nonsense-mutants":[29,95],"on":[30,96],"been":[36],"compared":[37],"by":[38],"a":[39,84],"level":[40,85],"eight":[42],"tRNA:":[43],"tRNATyr,":[44],"tRNAGln,":[45],"tRNATrp,":[46],"tRNALeu":[47],"tRNAArg":[49],"(previously":[50],"described":[51],"as":[52],"potentially":[53],"suppressor":[54,72],"tRNA),":[55],"also":[57],"tRNAPro,":[58],"tRNAHis":[59],"tRNAGly.":[61],"We":[62],"not":[64],"revealed":[65],"preferable":[66],"increase":[67,82],"amount":[69],"natural":[71],"tRNA.":[73,89],"The":[74,90],"majority":[75],"investigated":[78,88],"leads":[80],"to":[81],"all":[87],"mechanisms":[91],"providing":[92],"viability":[93],"are":[102],"discussed.":[103]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}