{"id":"https://openalex.org/W2403388397","doi":null,"title":"Age-related changes in the structure of myocardial collagen network of auricle of the right atrium in healthy persons and ischemic heart disease patients.","display_name":"Age-related changes in the structure of myocardial collagen network of auricle of the right atrium in healthy persons and ischemic heart disease patients.","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W2403388397","mag":"2403388397","pmid":"https://pubmed.ncbi.nlm.nih.gov/15758582"},"language":"en","primary_location":{"id":"pmid:15758582","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15758582","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicina (Kaunas, Lithuania)","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030016637","display_name":"Au\u0161ra Burkauskien\u0117","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I131736796","display_name":"Lithuanian University of Health Sciences","ror":"https://ror.org/0069bkg23","country_code":"LT","type":"education","lineage":["https://openalex.org/I131736796"]}],"countries":["LT"],"is_corresponding":true,"raw_author_name":"Ausra Burkauskiene","raw_affiliation_strings":["Institute of Anatomy, Kaunas University of Medicine, A. Mickeviciaus 9, 44307 Kaunas, Lithuania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Anatomy, Kaunas University of Medicine, A. Mickeviciaus 9, 44307 Kaunas, Lithuania","institution_ids":["https://openalex.org/I131736796"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030016637"],"corresponding_institution_ids":["https://openalex.org/I131736796"],"apc_list":null,"apc_paid":null,"fwci":0.6488,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.76439565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"41","issue":"2","first_page":"145","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.888700008392334,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.888700008392334,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.042899999767541885,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.008799999952316284,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/age-related-changes","display_name":"age-related changes","score":0.8550000190734863},{"id":"https://openalex.org/keywords/ischemic-heart-disease","display_name":"ischemic heart disease","score":0.9869999885559082},{"id":"https://openalex.org/keywords/collagen-bundles","display_name":"collagen bundles","score":0.7760000228881836},{"id":"https://openalex.org/keywords/endomysium","display_name":"endomysium","score":0.7580000162124634},{"id":"https://openalex.org/keywords/collagen-fiber-distribution","display_name":"collagen fiber distribution","score":0.35199999809265137},{"id":"https://openalex.org/keywords/myocardial-fibrosis","display_name":"myocardial fibrosis","score":0.5669999718666077},{"id":"https://openalex.org/keywords/cardiomyocytes","display_name":"cardiomyocytes","score":0.6079999804496765}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6947152614593506},{"id":"https://openalex.org/C2780801906","wikidata":"https://www.wikidata.org/wiki/Q379858","display_name":"Auricle","level":2,"score":0.682223379611969},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5389465093612671},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5222697854042053},{"id":"https://openalex.org/C2780074459","wikidata":"https://www.wikidata.org/wiki/Q389735","display_name":"Heart disease","level":2,"score":0.45389530062675476},{"id":"https://openalex.org/C114021368","wikidata":"https://www.wikidata.org/wiki/Q189265","display_name":"Atrium (architecture)","level":3,"score":0.4531051814556122},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4506913125514984},{"id":"https://openalex.org/C2986834420","wikidata":"https://www.wikidata.org/wiki/Q5932254","display_name":"Age groups","level":2,"score":0.41444748640060425},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3477754592895508},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.28582748770713806},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.10571840405464172},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001344","descriptor_name":"Autopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001706","descriptor_name":"Biopsy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006325","descriptor_name":"Heart Atria","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D006325","descriptor_name":"Heart Atria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006325","descriptor_name":"Heart Atria","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006652","descriptor_name":"Histological Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008853","descriptor_name":"Microscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017202","descriptor_name":"Myocardial Ischemia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D024022","descriptor_name":"Fibrillar Collagens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:15758582","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15758582","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicina (Kaunas, Lithuania)","raw_type":"Comparative Study"},{"id":"pmh:oai:elaba.lt:LT-eLABa-0001:J.04~2005~ISSN_1010-660X.V_41.N_2.PG_145-154","doi":null,"is_oa":false,"landing_page_url":"http://vddb.laba.lt/fedora/get/LT-eLABa-0001:J.04~2005~ISSN_1010-660X.V_41.N_2.PG_145-154/DS.002.1.01.ARTIC","pdf_url":null,"source":{"id":"https://openalex.org/S4306401980","display_name":"Laba (Lietuvos akademini\u0173 bibliotek\u0173 direktori\u0173 asociacija)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I188730046","host_organization_name":"Vytautas Magnus University","host_organization_lineage":["https://openalex.org/I188730046"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Medicina, ISSN 1010-660X, 2005, T. 41, Nr. 2, p. 145-154","raw_type":"Article"},{"id":"pmh:oai:lsmu.lt:20.500.12512/77136","doi":null,"is_oa":false,"landing_page_url":"http://www.ncbi.nlm.nih.gov/pubmed/15758582","pdf_url":null,"source":{"id":"https://openalex.org/S7407055191","display_name":"Lithuanian University of Health Sciences","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3188909295","https://openalex.org/W7132392945","https://openalex.org/W3201071884","https://openalex.org/W2059390518","https://openalex.org/W2071251073","https://openalex.org/W2405922006","https://openalex.org/W7221350373","https://openalex.org/W175295623","https://openalex.org/W2441106101","https://openalex.org/W2922597662"],"abstract_inverted_index":{"The":[0,136],"objective":[1],"of":[2,16,20,22,50,53,66,79,93,95,109,127,130,140,153,167,170,198,211,222,259,267,276,319,347],"the":[3,14,23,91,96,128,199],"study":[4,62],"was":[5,59,112,145,155,214],"to":[6,38,240],"examine":[7],"and":[8,43,76,116,157,161,176,242,255,265,317],"evaluate":[9],"morphometrically":[10],"age-related":[11,168],"changes":[12,169],"in":[13,26,44,142,173,196,205,227,238,286,295,297,322,327],"structure":[15],"myocardium":[17],"collagen":[18,110,131,171,193,212,245,252,273,307,333],"network":[19,111,172,194,213,217,253,308],"auricle":[21,94,197],"right":[24,97,200],"atrium":[25,98,201],"control":[27,143,174,228],"group":[28,144,175,305,331],"persons,":[29],"who":[30],"were":[31,105],"not":[32,184,270],"diagnosed":[33],"with":[34,203,220,263,280,299,312],"cardiac":[35],"pathology":[36],"leading":[37],"heart":[39,46,82,148,178,232,303,329],"lesion":[40],"or":[41],"overload,":[42],"ischemic":[45,81,147,177,231,302,328],"disease":[47,83,149,179,233,304,330],"patients.":[48],"Material":[49],"56":[51],"persons":[52,69,261],"both":[54,206,237],"genders":[55],"aged":[56],"20-94":[57],"years":[58],"used":[60],"for":[61],"purposes.":[63],"Biopsy":[64],"material":[65,78],"17":[67],"healthy":[68,260],"(control":[70],"group,":[71,181,234],"average":[72],"age":[73,86,204],"60.53+/-9.89":[74],"years)":[75,88],"autopsy":[77],"39":[80],"patients":[84,150],"(average":[85],"63.83+/-15.67":[87],"taken":[89],"from":[90],"basis":[92],"(specimen":[99],"size--2":[100],"mm":[101,160],"x":[102],"2":[103],"mm)":[104],"examined.":[106],"Morphometric":[107],"analysis":[108],"performed":[113],"using":[114],"histologic":[115],"video":[117],"morphometric":[118],"methods.":[119],"After":[120,165],"this":[121],"investigation":[122,166],"we":[123,190],"evaluated":[124],"quantitative":[125],"parameters":[126],"bundles":[129,141,154],"net--namely":[132],"area,":[133],"number,":[134],"perimeter.":[135],"percentile":[137],"occupied":[138],"area":[139,195,218,254,275,310],"17.6+/-2.5%;":[146],"group--26.8+/-2.9%;":[151],"number":[152,266,318],"4179+/-1073":[156],"2523+/-867;":[158],"perimeter--24163+/-3308":[159],"23426+/-409":[162],"mm,":[163],"respectively.":[164],"patients'":[180],"which":[182,343],"did":[183,269],"statistically":[185],"significantly":[186],"differed":[187],"by":[188,243,285],"age,":[189,264,313],"determined":[191],"that":[192],"increased":[202,262,279,311],"groups,":[207],"however,":[208,314],"spatial":[209],"distribution":[210],"different.":[215],"Collagen":[216],"enlarged":[219,236],"lengthening":[221],"its":[223,256,282],"fibers":[224,246,268,321,334],"along":[225],"cardiomyocytes":[226,241],"group.":[229],"In":[230,301],"it":[235],"parallel":[239,287,298],"separate":[244,320,332],"merging":[247],"into":[248],"bigger":[249],"bundles.":[250],"Fibrillar":[251],"total":[257,289,315],"perimeter":[258,316],"change.":[271],"Consequently,":[272,326],"fiber":[274],"one":[277],"location":[278],"age;":[281],"shape,":[283],"judging":[284],"increasing":[288],"perimeter,":[290],"became":[291],"branchier,":[292],"i.e.":[293],"proliferated":[294],"endomysium":[296],"cardiomyocytes.":[300],"fibrillar":[306],"percentage":[309],"visual":[323],"field":[324],"decreased.":[325],"merged,":[335],"their":[336],"locations":[337],"enlarged,":[338],"taking":[339],"an":[340],"integral":[341],"structure,":[342],"allowed":[344],"assuming":[345],"development":[346],"interstitial":[348],"fibrosis.":[349]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}