{"id":"https://openalex.org/W2403124709","doi":"https://doi.org/10.1007/978-1-61779-219-9_36","title":"MRI of CEST-Based Reporter Gene","display_name":"MRI of CEST-Based Reporter Gene","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2403124709","doi":"https://doi.org/10.1007/978-1-61779-219-9_36","mag":"2403124709","pmid":"https://pubmed.ncbi.nlm.nih.gov/21874505"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-61779-219-9_36","doi":"https://doi.org/10.1007/978-1-61779-219-9_36","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-61779-219-9_36","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2484100088","display_name":"In vivo NMR Imaging"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048398648","display_name":"Guanshu Liu","orcid":"https://orcid.org/0000-0002-8188-4332","observed_orcids":["https://orcid.org/0000-0002-8188-4332","https://orcid.org/0009-0002-4556-2923"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guanshu Liu","raw_affiliation_strings":["Department of Radiology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. guanshu@mri.jhu.edu","Department of Radiology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA. guanshu@mri.jhu.edu","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]},{"raw_affiliation_string":"Department of Radiology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045168252","display_name":"Assaf A. Gilad","orcid":"https://orcid.org/0000-0002-7272-7570","observed_orcids":["https://orcid.org/0000-0002-7272-7570"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Assaf A. Gilad","raw_affiliation_strings":["Institute for Cell Engineering, F.M. Kirby Research Center for Functional Brain Imaging, Johns Hopkins University School of Medicine, 21205, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Cell Engineering, F.M. Kirby Research Center for Functional Brain Imaging, Johns Hopkins University School of Medicine, 21205, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5045168252"],"corresponding_institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"],"apc_list":null,"apc_paid":null,"fwci":4.4037,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.93781634,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"771","issue":null,"first_page":"733","last_page":"746"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.8871999979019165,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.8871999979019165,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.06069999933242798,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11279","display_name":"Lanthanide and Transition Metal Complexes","score":0.021299999207258224,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemical-exchange-saturation-transfer","display_name":"chemical exchange saturation transfer","score":0.9430000185966492},{"id":"https://openalex.org/keywords/cest-mri","display_name":"CEST MRI","score":0.7839999794960022},{"id":"https://openalex.org/keywords/reporter-genes","display_name":"reporter genes","score":0.9350000023841858},{"id":"https://openalex.org/keywords/non-invasive-mri","display_name":"non-invasive MRI","score":0.7440000176429749},{"id":"https://openalex.org/keywords/gene-cloning","display_name":"gene cloning","score":0.5899999737739563},{"id":"https://openalex.org/keywords/protein-expression","display_name":"protein expression","score":0.6990000009536743}],"concepts":[{"id":"https://openalex.org/C161733203","wikidata":"https://www.wikidata.org/wiki/Q911828","display_name":"Reporter gene","level":4,"score":0.6920158863067627},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5502217411994934},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.49937963485717773},{"id":"https://openalex.org/C121050878","wikidata":"https://www.wikidata.org/wiki/Q5135020","display_name":"Cloning (programming)","level":2,"score":0.4355708956718445},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3910270929336548},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3282511830329895},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.32528358697891235},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2517561912536621},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.22472846508026123},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.22110357880592346},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18679922819137573},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.09804001450538635},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.09513702988624573},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017930","descriptor_name":"Genes, Reporter","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-61779-219-9_36","doi":"https://doi.org/10.1007/978-1-61779-219-9_36","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-61779-219-9_36","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology","raw_type":"book-chapter"},{"id":"pmid:21874505","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21874505","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in molecular biology (Clifton, N.J.)","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1492726842","https://openalex.org/W1972650282","https://openalex.org/W1976837084","https://openalex.org/W1991919920","https://openalex.org/W1993424429","https://openalex.org/W1995844056","https://openalex.org/W2001256439","https://openalex.org/W2006224145","https://openalex.org/W2009412483","https://openalex.org/W2023281573","https://openalex.org/W2039462446","https://openalex.org/W2051153807","https://openalex.org/W2056380295","https://openalex.org/W2063616884","https://openalex.org/W2072418533","https://openalex.org/W2074136578","https://openalex.org/W2101119412","https://openalex.org/W2127854543","https://openalex.org/W2130291666","https://openalex.org/W2130735928","https://openalex.org/W2148518504","https://openalex.org/W2171882555"],"related_works":["https://openalex.org/W2272196461","https://openalex.org/W4404619347","https://openalex.org/W3109058640","https://openalex.org/W1970672280","https://openalex.org/W2406948319","https://openalex.org/W2583334976","https://openalex.org/W4281763097","https://openalex.org/W4248290866","https://openalex.org/W4322723026","https://openalex.org/W1991919920"],"abstract_inverted_index":{"In":[0],"recent":[1,22],"years,":[2],"several":[3],"reporter":[4,26,40],"genes":[5,41],"have":[6],"been":[7],"designed":[8],"for":[9,34],"non-invasive":[10],"magnetic":[11],"resonance":[12],"imaging":[13,38],"(MRI).":[14],"Here,":[15],"we":[16],"offer":[17],"a":[18,44],"brief":[19],"summary":[20],"of":[21,39],"advances":[23],"in":[24,56],"MRI":[25],"gene":[27],"technology,":[28],"as":[29,31],"well":[30],"elaborated":[32],"protocols":[33,52],"cloning,":[35],"expression,":[36],"and":[37,60],"based":[42],"on":[43],"chemical":[45],"exchange":[46],"saturation":[47],"transfer":[48],"(CEST)":[49],"method.":[50],"These":[51],"emphasize":[53],"new":[54],"developments":[55],"CEST-MRI":[57],"data":[58],"acquisition":[59],"processing.":[61]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2013,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}