{"id":"https://openalex.org/W2402930740","doi":null,"title":"Hypercholesterolemia and early restenosis after carotid endarterectomy.","display_name":"Hypercholesterolemia and early restenosis after carotid endarterectomy.","publication_year":1987,"publication_date":"1987-03-01","ids":{"openalex":"https://openalex.org/W2402930740","mag":"2402930740","pmid":"https://pubmed.ncbi.nlm.nih.gov/3824155"},"language":"en","primary_location":{"id":"pmid:3824155","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3824155","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043623336","display_name":"Joseph H. Rapp","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J H Rapp","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079347414","display_name":"Peter G. Qvarfordt","orcid":"https://orcid.org/0000-0002-0256-7225","observed_orcids":["https://orcid.org/0000-0002-0256-7225"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Qvarfordt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070133359","display_name":"Krupski Wc","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W C Krupski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081348598","display_name":"Ehrenfeld Wk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W K Ehrenfeld","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5031365669","display_name":"Ronald J. Stoney","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R J Stoney","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8102,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.86111352,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"101","issue":"3","first_page":"277","last_page":"82"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10816","display_name":"Cerebrovascular and Carotid Artery Diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10227","display_name":"Acute Ischemic Stroke Management","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypercholesterolemia","display_name":"hypercholesterolemia","score":0.9679999947547913},{"id":"https://openalex.org/keywords/carotid-endarterectomy","display_name":"carotid endarterectomy","score":0.9160000085830688},{"id":"https://openalex.org/keywords/restenosis","display_name":"restenosis","score":0.9459999799728394},{"id":"https://openalex.org/keywords/recurrent-carotid-stenosis","display_name":"recurrent carotid stenosis","score":0.9309999942779541},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.8529999852180481},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.7419999837875366},{"id":"https://openalex.org/keywords/endothelial-injury","display_name":"endothelial injury","score":0.8700000047683716},{"id":"https://openalex.org/keywords/vascular-smooth-muscle-cell-proliferation","display_name":"vascular smooth muscle cell proliferation","score":0.652999997138977},{"id":"https://openalex.org/keywords/myointimal-hyperplasia","display_name":"myointimal hyperplasia","score":0.8640000224113464},{"id":"https://openalex.org/keywords/atherosclerosis-risk-factors","display_name":"atherosclerosis risk factors","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.948635458946228},{"id":"https://openalex.org/C2778283817","wikidata":"https://www.wikidata.org/wiki/Q6590597","display_name":"Restenosis","level":3,"score":0.8759130239486694},{"id":"https://openalex.org/C2781068581","wikidata":"https://www.wikidata.org/wiki/Q5045544","display_name":"Carotid endarterectomy","level":3,"score":0.6976242065429688},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.6825817823410034},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6383468508720398},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5779799818992615},{"id":"https://openalex.org/C2779745121","wikidata":"https://www.wikidata.org/wiki/Q81476","display_name":"Endarterectomy","level":3,"score":0.572379469871521},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5472235083580017},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.46545010805130005},{"id":"https://openalex.org/C2777466421","wikidata":"https://www.wikidata.org/wiki/Q1266890","display_name":"Vascular disease","level":2,"score":0.4492104649543762},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.4324015974998474},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4099382758140564},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.25879180431365967},{"id":"https://openalex.org/C2778583881","wikidata":"https://www.wikidata.org/wiki/Q1325542","display_name":"Stent","level":2,"score":0.07896202802658081},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001157","descriptor_name":"Arterial Occlusive Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D001157","descriptor_name":"Arterial Occlusive Diseases","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D002340","descriptor_name":"Carotid Artery Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002340","descriptor_name":"Carotid Artery Diseases","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D004691","descriptor_name":"Endarterectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006937","descriptor_name":"Hypercholesterolemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048909","descriptor_name":"Diabetes Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3824155","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3824155","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Surgery","raw_type":"Journal Article"},{"id":"mag:2402930740","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3824155","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2004355616","https://openalex.org/W1969180328","https://openalex.org/W2157142672","https://openalex.org/W1969751667","https://openalex.org/W2031854967","https://openalex.org/W114548997","https://openalex.org/W2112245060","https://openalex.org/W2428043915","https://openalex.org/W24739380","https://openalex.org/W4206978063"],"abstract_inverted_index":{"Cellular":[0],"proliferation":[1],"in":[2,11,39,129,166,202],"response":[3,22,65],"to":[4,54],"endothelial":[5],"injury":[6,35],"has":[7,212],"been":[8],"examined":[9],"extensively":[10],"experimental":[12],"animals.":[13],"Under":[14],"certain":[15],"conditions":[16],"(e.g.,":[17],"hypercholesterolemia":[18,211],"and":[19,26,42,69,98,182,228,240],"hypertension),":[20],"this":[21],"can":[23],"be":[24,52,235],"exaggerated":[25,63],"develop":[27],"into":[28],"lesions":[29],"that":[30,49,174,210,229],"resemble":[31],"early":[32,87,217,239],"atherosclerosis.":[33],"The":[34,116,207],"caused":[36],"by":[37],"endarterectomy":[38,113,221],"human":[40],"beings":[41],"the":[43,46,55,130,143,162,176,203],"repair":[44],"of":[45,76,105,134,139,175,188,205],"arterial":[47],"wall":[48],"ensues":[50],"may":[51,234],"analogous":[53],"animal":[56],"models.":[57],"Presumably,":[58],"those":[59],"patients":[60,85,92,108],"with":[61,86,93,101,216,224,237],"an":[62],"proliferative":[64],"manifest":[66],"myointimal":[67],"hyperplasia":[68],"recurrent":[70,77,226,242],"stenosis.":[71,243],"To":[72],"determine":[73],"potential":[74],"causes":[75],"stenosis":[78],"after":[79,219],"carotid":[80,112,220],"endarterectomy,":[81],"we":[82],"studied":[83],"31":[84],"restenosis":[88,95,218],"(group":[89,96,114],"I),":[90],"35":[91],"later":[94],"II),":[97],"compared":[99],"them":[100],"a":[102,185,213],"control":[103,177],"group":[104,148,167],"100":[106],"consecutive":[107],"who":[109],"underwent":[110],"uncomplicated":[111],"III).":[115],"known":[117],"risk":[118],"factors":[119],"for":[120,147,194],"atherosclerosis":[121],"were":[122,199],"analyzed.":[123],"There":[124,198],"was":[125,150,169],"no":[126,200],"significant":[127],"difference":[128],"male-to-female":[131],"ratio,":[132],"number":[133],"cigarettes":[135],"smoked,":[136],"or":[137],"incidence":[138,187],"diabetes":[140],"mellitus.":[141],"However,":[142],"serum":[144,163],"cholesterol":[145,164],"level":[146,165],"I":[149,181],"282":[151],"+/-":[152],"57":[153],"mg/dl":[154],"(p":[155,190],"less":[156,191],"than":[157,192],"0.001":[158],"versus":[159,196],"controls)":[160],"while":[161],"II":[168,183],"not":[170,223],"significantly":[171],"elevated":[172],"over":[173],"group.":[178],"Both":[179],"groups":[180],"had":[184],"higher":[186],"hypertension":[189],"0.005":[193],"both":[195,238],"controls).":[197],"differences":[201],"severity":[204],"hypertension.":[206],"data":[208],"suggest":[209],"strong":[214],"association":[215],"but":[222],"late":[225,241],"disease":[227],"hypertension,":[230],"even":[231],"when":[232],"treated,":[233],"associated":[236]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}