{"id":"https://openalex.org/W24027751","doi":"https://doi.org/10.1016/s0021-9258(18)51434-4","title":"THE UTILIZATION OF \u03b2-HYDROXYBUTYRIC ACID BY THE LACTATING MAMMARY GLAND","display_name":"THE UTILIZATION OF \u03b2-HYDROXYBUTYRIC ACID BY THE LACTATING MAMMARY GLAND","publication_year":1941,"publication_date":"1941-03-01","ids":{"openalex":"https://openalex.org/W24027751","doi":"https://doi.org/10.1016/s0021-9258(18)51434-4","mag":"24027751"},"language":"en","primary_location":{"id":"doi:10.1016/s0021-9258(18)51434-4","doi":"https://doi.org/10.1016/s0021-9258(18)51434-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0021-9258(18)51434-4","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/s0021-9258(18)51434-4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103384820","display_name":"Joseph C. Shaw","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J.C. Shaw","raw_affiliation_strings":["Department of Dairy Industry, Stows Agricultural Experiment Station, Storm, Connecticut"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dairy Industry, Stows Agricultural Experiment Station, Storm, Connecticut","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033642303","display_name":"C.B. Knodt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C.B. Knodt","raw_affiliation_strings":["Department of Dairy Industry, Stows Agricultural Experiment Station, Storm, Connecticut"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dairy Industry, Stows Agricultural Experiment Station, Storm, Connecticut","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":3.1841,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.89919355,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"138","issue":"1","first_page":"287","last_page":"292"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10098","display_name":"Ruminant Nutrition and Digestive Physiology","score":0.0681999996304512,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12267","display_name":"Diet and metabolism studies","score":0.016899999231100082,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beta-hydroxybutyrate","display_name":"beta-hydroxybutyrate","score":0.9570000171661377},{"id":"https://openalex.org/keywords/lactating-mammary-gland","display_name":"lactating mammary gland","score":0.925000011920929},{"id":"https://openalex.org/keywords/milk-fat-secretion","display_name":"milk fat secretion","score":0.7319999933242798},{"id":"https://openalex.org/keywords/ketone-body-metabolism","display_name":"ketone body metabolism","score":0.8090000152587891},{"id":"https://openalex.org/keywords/ketone-bodies","display_name":"ketone bodies","score":0.7450000047683716},{"id":"https://openalex.org/keywords/fat-metabolism","display_name":"fat metabolism","score":0.5770000219345093},{"id":"https://openalex.org/keywords/energy-metabolism","display_name":"energy metabolism","score":0.5450000166893005},{"id":"https://openalex.org/keywords/cattle","display_name":"cattle","score":0.335999995470047}],"concepts":[{"id":"https://openalex.org/C2778001805","wikidata":"https://www.wikidata.org/wiki/Q189961","display_name":"Mammary gland","level":4,"score":0.7467407584190369},{"id":"https://openalex.org/C2776659692","wikidata":"https://www.wikidata.org/wiki/Q719426","display_name":"Lactation","level":3,"score":0.5761919617652893},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5260700583457947},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4485347867012024},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3955203592777252},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3902098536491394},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3213287591934204},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.1573258936405182},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14624884724617004},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.06420308351516724},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0021-9258(18)51434-4","doi":"https://doi.org/10.1016/s0021-9258(18)51434-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0021-9258(18)51434-4","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/s0021-9258(18)51434-4","doi":"https://doi.org/10.1016/s0021-9258(18)51434-4","is_oa":true,"landing_page_url":"https://doi.org/10.1016/s0021-9258(18)51434-4","pdf_url":null,"source":{"id":"https://openalex.org/S140251998","display_name":"Journal of Biological Chemistry","issn_l":"0021-9258","issn":["0021-9258","1067-8816","1083-351X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biological Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W175354666","https://openalex.org/W1497890785","https://openalex.org/W2095986674","https://openalex.org/W2320892315","https://openalex.org/W2323777378","https://openalex.org/W2339932964","https://openalex.org/W2474910604","https://openalex.org/W2618335054","https://openalex.org/W4205930252"],"related_works":["https://openalex.org/W2018368185","https://openalex.org/W2231731705","https://openalex.org/W52464491","https://openalex.org/W2321822496","https://openalex.org/W2093869214","https://openalex.org/W2413942302","https://openalex.org/W1495334013","https://openalex.org/W1984676470","https://openalex.org/W2591974028","https://openalex.org/W2106356841"],"abstract_inverted_index":{"The":[0],"arteriovenous":[1],"studies":[2],"of":[3,13,41,45,50,63,67,72,112,134,137,143],"Shaw":[4],"and":[5,88,94,97],"Petersen":[6],"(1,":[7],"2)":[8],"have":[9],"demonstrated":[10],"that":[11,30,101],"most":[12],"the":[14,28,31,39,46,51,61,64,68,70,108,113,132,135,141,147],"milk":[15],"fat":[16,65,144],"is":[17,78],"derived":[18],"from":[19],"blood":[20],"fat.No":[21],"consideration,":[22],"however,":[23],"has":[24,81],"been":[25,82],"given":[26],"to":[27,55],"r81e":[29],"intermediate":[32],"substance,":[33],"@hydroxybutyric":[34],"acid,":[35],"may":[36],"play":[37],"in":[38,146],"secretion":[40],"milk.Accordingly":[42],"a":[43],"study":[44],"acetone":[47,117,138],"body":[48],"metabolism":[49,66],"gland":[52,105,111],"was":[53],"initiated":[54],"gain":[56],"some":[57],"further":[58],"insight":[59],"into":[60],"mechanism":[62],"gland.That":[69],"utilization":[71],"ketone":[73],"bodies":[74,118,139],"by":[75,84],"normal":[76],"tissues":[77],"quite":[79],"high":[80],"shown":[83],"Marriott":[85],"(3),":[86],"Snapper":[87],"Griinbaum":[89],"(4),":[90],"Barnes,":[91],"MacKay,":[92],"Moe,":[93],"Escher":[95],"(5),":[96],"others.It":[98],"appeared":[99],"possible":[100],"an":[102],"actively":[103],"secreting":[104],"such":[106],"as":[107,140],"lactating":[109],"mammary":[110],"cow":[114],"would":[115],"use":[116],"for":[119,125],"energy":[120],"purposes":[121],"if":[122],"not":[123],"indeed":[124],"actual":[126],"synthesis,":[127],"although":[128],"there":[129],"also":[130],"remained":[131],"possibility":[133],"production":[136],"result":[142],"oxidation":[145],"gland.":[148],"Methods":[149]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}