{"id":"https://openalex.org/W2402620153","doi":null,"title":"The significance of mycobacterium tuberculosis antibody, antigen 60 IgG in patients with abnormal chest radiography.","display_name":"The significance of mycobacterium tuberculosis antibody, antigen 60 IgG in patients with abnormal chest radiography.","publication_year":2004,"publication_date":"2004-12-01","ids":{"openalex":"https://openalex.org/W2402620153","mag":"2402620153","pmid":"https://pubmed.ncbi.nlm.nih.gov/15754776"},"language":"en","primary_location":{"id":"pmid:15754776","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15754776","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chang Gung medical journal","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068437030","display_name":"Huang-Pin Wu","orcid":"https://orcid.org/0000-0002-8906-4566","observed_orcids":["https://orcid.org/0000-0002-8906-4566"]},"institutions":[{"id":"https://openalex.org/I3020100970","display_name":"Chang Gung Memorial Hospital","ror":"https://ror.org/02verss31","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I3020100970"]},{"id":"https://openalex.org/I4210111603","display_name":"Keelung Chang Gung Memorial Hospital","ror":"https://ror.org/020dg9f27","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210111603"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Huang-Pin Wu","raw_affiliation_strings":["Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Chang Gung Memorial Hospital, Keelung","institution_ids":["https://openalex.org/I3020100970","https://openalex.org/I4210111603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111428467","display_name":"Wen-Bin Shieh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wen-Bin Shieh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032118051","display_name":"Fang-Keui Hsien","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3020100970","display_name":"Chang Gung Memorial Hospital","ror":"https://ror.org/02verss31","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I3020100970"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Fang-Keui Hsien","raw_affiliation_strings":["Chang Gung Medical Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chang Gung Medical Foundation","institution_ids":["https://openalex.org/I3020100970"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053343127","display_name":"Chung\u2010Ching Hua","orcid":"https://orcid.org/0000-0002-2902-751X","observed_orcids":["https://orcid.org/0000-0002-2902-751X"]},"institutions":[{"id":"https://openalex.org/I3020100970","display_name":"Chang Gung Memorial Hospital","ror":"https://ror.org/02verss31","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I3020100970"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chung-Ching Hua","raw_affiliation_strings":["Chang Gung Medical Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chang Gung Medical Foundation","institution_ids":["https://openalex.org/I3020100970"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6318,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.72024661,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"27","issue":"12","first_page":"869","last_page":"76"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12578","display_name":"Diagnosis and treatment of tuberculosis","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.671999990940094},{"id":"https://openalex.org/keywords/serological-diagnosis","display_name":"serological diagnosis","score":0.8709999918937683},{"id":"https://openalex.org/keywords/pulmonary-tuberculosis","display_name":"pulmonary tuberculosis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.8669999837875366},{"id":"https://openalex.org/keywords/acid-fast-bacilli","display_name":"acid-fast bacilli","score":0.8370000123977661},{"id":"https://openalex.org/keywords/smear-negative-pulmonary-tuberculosis","display_name":"smear-negative tuberculosis","score":0.7789999842643738},{"id":"https://openalex.org/keywords/cutoff-values","display_name":"cut-off values","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.945631742477417},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.6733200550079346},{"id":"https://openalex.org/C36454342","wikidata":"https://www.wikidata.org/wiki/Q245341","display_name":"Radiography","level":2,"score":0.6535063982009888},{"id":"https://openalex.org/C2776301714","wikidata":"https://www.wikidata.org/wiki/Q259346","display_name":"Sputum","level":3,"score":0.616652250289917},{"id":"https://openalex.org/C144494922","wikidata":"https://www.wikidata.org/wiki/Q6547272","display_name":"Likelihood ratios in diagnostic testing","level":3,"score":0.6002697944641113},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.5944291949272156},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.5622637867927551},{"id":"https://openalex.org/C2781137159","wikidata":"https://www.wikidata.org/wiki/Q1283318","display_name":"Chest radiograph","level":3,"score":0.5474536418914795},{"id":"https://openalex.org/C53789813","wikidata":"https://www.wikidata.org/wiki/Q3553769","display_name":"Positive predicative value","level":3,"score":0.49954748153686523},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.49577388167381287},{"id":"https://openalex.org/C2779912665","wikidata":"https://www.wikidata.org/wiki/Q7581635","display_name":"Sputum culture","level":4,"score":0.47944846749305725},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4685301184654236},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.43599462509155273},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.43497127294540405},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4263215959072113},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.41989976167678833},{"id":"https://openalex.org/C3019719930","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value","level":2,"score":0.3874537944793701},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.30491316318511963},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.255228191614151}],"mesh":[{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014397","descriptor_name":"Tuberculosis, Pulmonary","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014397","descriptor_name":"Tuberculosis, Pulmonary","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D014397","descriptor_name":"Tuberculosis, Pulmonary","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:15754776","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15754776","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chang Gung medical journal","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.573.2868","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.573.2868","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://memo.cgu.edu.tw/cgmj/2712/271202.pdf","raw_type":"text"},{"id":"mag:2402620153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15754776","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W77898364","https://openalex.org/W1899728192","https://openalex.org/W1906692317","https://openalex.org/W1985546858","https://openalex.org/W1989068512","https://openalex.org/W2000404373","https://openalex.org/W2015870643","https://openalex.org/W2021547209","https://openalex.org/W2024503913","https://openalex.org/W2026257303","https://openalex.org/W2029277083","https://openalex.org/W2033140693","https://openalex.org/W2042967546","https://openalex.org/W2043464691","https://openalex.org/W2044748271","https://openalex.org/W2062974807","https://openalex.org/W2066120344","https://openalex.org/W2067648084","https://openalex.org/W2075803850","https://openalex.org/W2092057346","https://openalex.org/W2107495096","https://openalex.org/W2124376346","https://openalex.org/W2134660914","https://openalex.org/W2144465462","https://openalex.org/W2166578844","https://openalex.org/W2296816112","https://openalex.org/W2400590806","https://openalex.org/W2408802448","https://openalex.org/W2418210342"],"related_works":["https://openalex.org/W7097468609","https://openalex.org/W24825424","https://openalex.org/W1979236511","https://openalex.org/W2078675520","https://openalex.org/W1981810555","https://openalex.org/W2105933604","https://openalex.org/W2048052391","https://openalex.org/W1966946832","https://openalex.org/W2276344543","https://openalex.org/W4244015600"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,27,39,114,133,149,169,186],"identification":[2],"of":[3,15,20,30,41,51,73,86,116,136,173,183,223,240,252],"acid-fast":[4],"bacilli":[5],"(AFB)":[6],"in":[7,58,69,218,237],"sputum":[8,219],"or":[9,101],"tissue":[10],"is":[11,22],"the":[12,47,70,177,184,224,238],"definite":[13],"diagnosis":[14,21,29,72,251],"tuberculosis.":[16,75,254],"However,":[17],"this":[18,42],"method":[19],"restricted":[23],"by":[24],"certain":[25],"limitations.":[26],"serologic":[28,71],"tuberculosis":[31,94,126],"has":[32],"been":[33,82],"used":[34],"for":[35,161,198,209],"a":[36,143,232],"long":[37],"time.":[38],"aim":[40],"study":[43],"was":[44,106,139],"to":[45,65,142],"determine":[46],"sensitivity":[48,178],"and":[49,64,88,128,158,163,180,190,195,204,206,215,229],"specificity":[50,181],"Antigen":[52],"60":[53],"(A60)":[54],"immunoglobulin":[55],"G":[56],"(IgG)":[57],"patients":[59,79,199,210],"with":[60,200,211],"abnormal":[61,201,212,242],"chest":[62,124,202,213,243],"radiography":[63,203,214,244],"assess":[66],"its":[67],"application":[68],"pulmonary":[74,93,98,103,253],"METHODS:":[76],"Data":[77],"on":[78],"who":[80],"had":[81],"diagnosed":[83],"using":[84,119],"results":[85],"culture":[87,127],"pathology":[89,129],"as":[90],"having":[91],"active":[92],"(N=178),":[95],"other":[96],"non-tuberculosis":[97],"disease":[99,104],"(N=34),":[100],"no":[102],"(N=117)":[105],"collected":[107],"from":[108],"January":[109],"2001":[110],"through":[111],"December":[112],"2002.":[113],"data":[115],"A60":[117,137,234],"IgG":[118,138,235],"enzyme-linked":[120],"immunosorbent":[121],"assay":[122],"(ELISA),":[123],"radiography,":[125],"were":[130,166,193],"obtained":[131],"retrospectively.":[132],"cutoff":[134,171],"value":[135,157,172,189,228],"chosen":[140,170],"according":[141],"receiver":[144],"operating":[145],"characteristic":[146],"(ROC)":[147],"analysis.":[148],"sensitivity,":[150],"specificity,":[151],"positive":[152,162,187,226,233],"predictive":[153,156,188,227],"value,":[154],"negative":[155,164,216],"likelihood":[159,191,230],"ratio":[160,192],"test":[165,236],"determined.":[167],"RESULTS:":[168],"261.2":[174],"units":[175],"defined":[176],"(49.4%)":[179],"(79.5%)":[182],"test.":[185],"95.7%":[194],"4.20,":[196],"respectively,":[197,208],"88.2%":[205],"2.97,":[207],"AFB":[217],"smear.":[220],"CONCLUSIONS:":[221],"Because":[222],"high":[225],"ratio,":[231],"presence":[239],"an":[241,248],"can":[245],"help":[246],"make":[247],"accurate":[249],"clinical":[250]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}