{"id":"https://openalex.org/W2402347110","doi":"https://doi.org/10.3727/096504015x14478843952942","title":"Apoptotic Melanoma B16-F1 Cells Induced by Lidamycin Could Initiate the Antitumor Immune Response in BABL/c Mice","display_name":"Apoptotic Melanoma B16-F1 Cells Induced by Lidamycin Could Initiate the Antitumor Immune Response in BABL/c Mice","publication_year":2016,"publication_date":"2016-01-16","ids":{"openalex":"https://openalex.org/W2402347110","doi":"https://doi.org/10.3727/096504015x14478843952942","mag":"2402347110","pmid":"https://pubmed.ncbi.nlm.nih.gov/26802654","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7842507"},"language":"en","primary_location":{"id":"doi:10.3727/096504015x14478843952942","doi":"https://doi.org/10.3727/096504015x14478843952942","is_oa":true,"landing_page_url":"https://doi.org/10.3727/096504015x14478843952942","pdf_url":null,"source":{"id":"https://openalex.org/S146643948","display_name":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","issn_l":"0965-0407","issn":["0965-0407","1555-3906"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4360969325","host_organization_name":"Cognizant Communication Corporation","host_organization_lineage":["https://openalex.org/P4360969325"],"host_organization_lineage_names":["Cognizant Communication Corporation"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.3727/096504015x14478843952942","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101990467","display_name":"Jianlin Yang","orcid":"https://orcid.org/0000-0002-2201-2913","observed_orcids":["https://orcid.org/0000-0002-2201-2913"]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian-lin Yang","raw_affiliation_strings":["China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China","institution_ids":["https://openalex.org/I161350542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100654753","display_name":"Qin Ye","orcid":"https://orcid.org/0000-0001-7842-4397","observed_orcids":["https://orcid.org/0000-0001-7842-4397","https://orcid.org/0009-0003-7366-6399"]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ye Qin","raw_affiliation_strings":["*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China","institution_ids":["https://openalex.org/I161350542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100420704","display_name":"Liang Li","orcid":"https://orcid.org/0000-0003-0745-2571","observed_orcids":["https://orcid.org/0000-0003-0745-2571"]},"institutions":[{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Li","raw_affiliation_strings":["\u2020Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u2020Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China","institution_ids":["https://openalex.org/I200296433"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Chu-yu Cao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chu-yu Cao","raw_affiliation_strings":["*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China","institution_ids":["https://openalex.org/I161350542"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qing Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Wang","raw_affiliation_strings":["*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China","institution_ids":["https://openalex.org/I161350542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100340588","display_name":"Qian Li","orcid":"https://orcid.org/0000-0002-4212-1746","observed_orcids":["https://orcid.org/0000-0002-4212-1746"]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Li","raw_affiliation_strings":["*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China","institution_ids":["https://openalex.org/I161350542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072692333","display_name":"Yafeng Lv","orcid":"https://orcid.org/0000-0003-1873-593X","observed_orcids":["https://orcid.org/0000-0003-1873-593X"]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ya-feng Lv","raw_affiliation_strings":["*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China","institution_ids":["https://openalex.org/I161350542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100350717","display_name":"Yanlin Wang","orcid":"https://orcid.org/0000-0002-6908-1529","observed_orcids":["https://orcid.org/0000-0002-6908-1529"]},"institutions":[{"id":"https://openalex.org/I161350542","display_name":"China Three Gorges University","ror":"https://ror.org/0419nfc77","country_code":"CN","type":"education","lineage":["https://openalex.org/I161350542"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanlin Wang","raw_affiliation_strings":["*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*China Three Gorges University Medical College, Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, China","institution_ids":["https://openalex.org/I161350542"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4039,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.68019493,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"23","issue":"1","first_page":"79","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lidamycin","display_name":"lidamycin","score":0.847000002861023},{"id":"https://openalex.org/keywords/immunogenic-cell-death","display_name":"immunogenic cell death","score":0.9539999961853027},{"id":"https://openalex.org/keywords/b16f1-melanoma-cells","display_name":"B16F1 melanoma cells","score":0.7789999842643738},{"id":"https://openalex.org/keywords/tumor-cell-apoptosis","display_name":"tumor cell apoptosis","score":0.6639999747276306},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.8970000147819519},{"id":"https://openalex.org/keywords/dendritic-cell-phagocytosis","display_name":"dendritic cell phagocytosis","score":0.8109999895095825},{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8539999723434448},{"id":"https://openalex.org/keywords/nk-cell-cytotoxicity","display_name":"NK cell cytotoxicity","score":0.7960000038146973},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.7839999794960022},{"id":"https://openalex.org/keywords/enediyne-antibiotics","display_name":"enediyne antibiotics","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C2777877232","wikidata":"https://www.wikidata.org/wiki/Q17144704","display_name":"Immunogenic cell death","level":4,"score":0.7582509517669678},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6602504253387451},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.5531465411186218},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.5315309166908264},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.5249293446540833},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.514069676399231},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.5096879005432129},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.48450610041618347},{"id":"https://openalex.org/C47450691","wikidata":"https://www.wikidata.org/wiki/Q634510","display_name":"Calreticulin","level":3,"score":0.4742497503757477},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4302576780319214},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42700421810150146},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.41412001848220825},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4081440567970276},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.39577096700668335},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.3243309259414673},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.24831873178482056},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2440866231918335},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.12307214736938477},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06784570217132568},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000617","descriptor_name":"Aminoglycosides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000903","descriptor_name":"Antibiotics, Antineoplastic","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004354","descriptor_name":"Drug Screening Assays, Antitumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008546","descriptor_name":"Melanoma, Experimental","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008546","descriptor_name":"Melanoma, Experimental","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008546","descriptor_name":"Melanoma, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009368","descriptor_name":"Neoplasm Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010587","descriptor_name":"Phagocytosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053281","descriptor_name":"Enediynes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D064032","descriptor_name":"Calbindin 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3727/096504015x14478843952942","doi":"https://doi.org/10.3727/096504015x14478843952942","is_oa":true,"landing_page_url":"https://doi.org/10.3727/096504015x14478843952942","pdf_url":null,"source":{"id":"https://openalex.org/S146643948","display_name":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","issn_l":"0965-0407","issn":["0965-0407","1555-3906"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4360969325","host_organization_name":"Cognizant Communication Corporation","host_organization_lineage":["https://openalex.org/P4360969325"],"host_organization_lineage_names":["Cognizant Communication Corporation"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7842507","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7842507","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncol Res","raw_type":"Text"},{"id":"pmid:26802654","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26802654","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3727/096504015x14478843952942","doi":"https://doi.org/10.3727/096504015x14478843952942","is_oa":true,"landing_page_url":"https://doi.org/10.3727/096504015x14478843952942","pdf_url":null,"source":{"id":"https://openalex.org/S146643948","display_name":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","issn_l":"0965-0407","issn":["0965-0407","1555-3906"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","medline","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4360969325","host_organization_name":"Cognizant Communication Corporation","host_organization_lineage":["https://openalex.org/P4360969325"],"host_organization_lineage_names":["Cognizant Communication Corporation"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1482605569","https://openalex.org/W1985271970","https://openalex.org/W1985869366","https://openalex.org/W1991733308","https://openalex.org/W1993401160","https://openalex.org/W1994974939","https://openalex.org/W1997245052","https://openalex.org/W2002260288","https://openalex.org/W2002980383","https://openalex.org/W2016612145","https://openalex.org/W2030998537","https://openalex.org/W2037372204","https://openalex.org/W2050824673","https://openalex.org/W2053848211","https://openalex.org/W2056817526","https://openalex.org/W2061254174","https://openalex.org/W2069419117","https://openalex.org/W2090750060","https://openalex.org/W2095472825","https://openalex.org/W2106083164","https://openalex.org/W2107075277","https://openalex.org/W2120426523","https://openalex.org/W2162297351","https://openalex.org/W2187421296","https://openalex.org/W2393980178","https://openalex.org/W2514765080","https://openalex.org/W2583986277"],"related_works":["https://openalex.org/W2107075277","https://openalex.org/W2061254174","https://openalex.org/W7120324561","https://openalex.org/W2029600243","https://openalex.org/W2093168988","https://openalex.org/W2766975478","https://openalex.org/W2130590529","https://openalex.org/W3119761705","https://openalex.org/W1993401160","https://openalex.org/W2054160094"],"abstract_inverted_index":{"In":[0,67],"the":[1,20,29,70,80,106,126,141,151,154,168,193],"process":[2],"of":[3,82,97,189,224],"tumor":[4,24,43,136],"cell":[5,21,51,87,107,208,225],"apoptosis":[6,96],"induced":[7],"by":[8,102,120],"specific":[9,155],"regents,":[10],"calreticulin":[11],"(CRT)":[12],"was":[13,159],"transferred":[14],"from":[15,167,196],"endoplasmic":[16],"reticulum":[17],"(ER)":[18],"onto":[19,105],"membrane.":[22,108],"These":[23,109],"cells,":[25,100,212],"when":[26,191],"used":[27,77,132,220],"as":[28,49,133,221],"cellular":[30,194],"vaccine":[31,137,226],"to":[32,48,64,78,138,227],"immunize":[33],"experimental":[34],"animals,":[35],"could":[36,94,113,205,218],"initiate":[37,228],"effective":[38,229],"antitumor":[39,156,230],"immunoresponse":[40,231],"against":[41,145],"homologous":[42],"cells.":[44,66,124,149,198],"This":[45],"is":[46,55],"referred":[47],"immunogenic":[50,86,207],"death.":[52,88],"Lidamycin":[53],"(LDM)":[54],"an":[56],"enediyne":[57],"antibiotic,":[58],"which":[59],"has":[60],"extremely":[61],"potent":[62],"cytotoxicity":[63],"cancer":[65,74,99],"this":[68],"study,":[69],"mouse":[71],"melanoma":[72],"B16-F1":[73,98,111,129,147,173,197,211,216],"cells":[75,112,130,174,217],"were":[76,131],"investigate":[79],"ability":[81],"LDM":[83,93,204],"in":[84,161,210,232],"promoting":[85],"Our":[89],"data":[90],"showed":[91,175],"that":[92,203],"induce":[95],"accompanied":[101],"CRT":[103],"translocation":[104],"LDM-treated":[110,127,172,215],"be":[114,219],"recognized":[115],"and":[116,122,181,186,213],"phagocytosed":[117],"more":[118],"efficiently":[119],"macrophage":[121],"dendritic":[123],"When":[125],"apoptotic":[128],"a":[134,222],"whole-cell":[135],"immune":[139,157],"mice,":[140],"mice":[142,169],"obtained":[143],"resistance":[144],"rechallenged":[146],"living":[148],"At":[150],"same":[152],"time,":[153],"response":[158],"observed":[160],"these":[162,200,214],"vaccinated":[163,170],"mice.":[164,233],"The":[165],"splenocytes":[166],"with":[171],"significantly":[176],"enhanced":[177],"NK":[178],"lymphocyte":[179],"activities":[180],"also":[182],"faster":[183],"growth":[184],"rate":[185],"increased":[187],"secretion":[188],"IFN-\u03b3":[190],"encountering":[192],"antigens":[195],"All":[199],"results":[201],"suggested":[202],"promote":[206],"death":[209],"sort":[223]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}