{"id":"https://openalex.org/W2401766367","doi":null,"title":"Regulation of PP1 and Nucleic Acid binding by AKAP149 and PNUTS","display_name":"Regulation of PP1 and Nucleic Acid binding by AKAP149 and PNUTS","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2401766367","mag":"2401766367"},"language":"en","primary_location":{"id":"pmh:oai:www.duo.uio.no:10852/28127","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/28127","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10852/28127","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069454824","display_name":"Marie Rogne","orcid":"https://orcid.org/0000-0002-3594-9000","observed_orcids":["https://orcid.org/0000-0002-3594-9000"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Marie Rogne","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3594-9000","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5069454824"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pnuts","display_name":"PNUTS","score":0.9900000095367432},{"id":"https://openalex.org/keywords/protein-phosphatase-1","display_name":"protein phosphatase 1","score":0.8790000081062317},{"id":"https://openalex.org/keywords/nucleic-acid-binding","display_name":"nucleic acid binding","score":0.9010000228881836},{"id":"https://openalex.org/keywords/kh-domain","display_name":"KH domain","score":0.8529999852180481},{"id":"https://openalex.org/keywords/mitochondrial-network","display_name":"mitochondrial network","score":0.5410000085830688},{"id":"https://openalex.org/keywords/mitochondrial-positioning","display_name":"mitochondrial positioning","score":0.6019999980926514},{"id":"https://openalex.org/keywords/mitochondrial-dysfunction","display_name":"mitochondrial dysfunction","score":0.675000011920929},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.8980000019073486},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8159999847412109},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.996999979019165},{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":0.9300000071525574},{"id":"https://openalex.org/keywords/rna-binding","display_name":"RNA binding","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.5688513517379761},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39382731914520264},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32194405794143677},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3131222724914551},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30416420102119446}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:www.duo.uio.no:10852/28127","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/28127","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2401766367","doi":null,"is_oa":false,"landing_page_url":"https://www.duo.uio.no/bitstream/handle/10852/28127/745_Rogne_utenxart.pdf?sequence=1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:www.duo.uio.no:10852/28127","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10852/28127","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":230,"referenced_works":["https://openalex.org/W61683551","https://openalex.org/W147106477","https://openalex.org/W276165663","https://openalex.org/W338601501","https://openalex.org/W1485233538","https://openalex.org/W1502567507","https://openalex.org/W1530102523","https://openalex.org/W1531850676","https://openalex.org/W1538004262","https://openalex.org/W1578127015","https://openalex.org/W1606409542","https://openalex.org/W1778749218","https://openalex.org/W1790543114","https://openalex.org/W1856940032","https://openalex.org/W1905864598","https://openalex.org/W1918374985","https://openalex.org/W1956175627","https://openalex.org/W1966723276","https://openalex.org/W1967364632","https://openalex.org/W1967882515","https://openalex.org/W1967941831","https://openalex.org/W1968683907","https://openalex.org/W1969209269","https://openalex.org/W1969568463","https://openalex.org/W1969972660","https://openalex.org/W1970166464","https://openalex.org/W1970398821","https://openalex.org/W1971461646","https://openalex.org/W1971733888","https://openalex.org/W1971959845","https://openalex.org/W1972689181","https://openalex.org/W1974777272","https://openalex.org/W1976614574","https://openalex.org/W1976781795","https://openalex.org/W1978019490","https://openalex.org/W1983371173","https://openalex.org/W1983859430","https://openalex.org/W1986158928","https://openalex.org/W1987174568","https://openalex.org/W1989674463","https://openalex.org/W1990428135","https://openalex.org/W1990454779","https://openalex.org/W1991101546","https://openalex.org/W1991727881","https://openalex.org/W1993222258","https://openalex.org/W1994810131","https://openalex.org/W1995405908","https://openalex.org/W1995690959","https://openalex.org/W1999074203","https://openalex.org/W1999730046","https://openalex.org/W1999861460","https://openalex.org/W2000990440","https://openalex.org/W2002276332","https://openalex.org/W2003209186","https://openalex.org/W2003402389","https://openalex.org/W2005487999","https://openalex.org/W2005699094","https://openalex.org/W2007427545","https://openalex.org/W2008896087","https://openalex.org/W2009821764","https://openalex.org/W2009876130","https://openalex.org/W2012469190","https://openalex.org/W2013801092","https://openalex.org/W2014285665","https://openalex.org/W2014977510","https://openalex.org/W2015000379","https://openalex.org/W2016706874","https://openalex.org/W2019017938","https://openalex.org/W2020033597","https://openalex.org/W2021194721","https://openalex.org/W2022616695","https://openalex.org/W2022713347","https://openalex.org/W2023133625","https://openalex.org/W2023823346","https://openalex.org/W2026920763","https://openalex.org/W2027339928","https://openalex.org/W2029479878","https://openalex.org/W2029709883","https://openalex.org/W2029864805","https://openalex.org/W2030844064","https://openalex.org/W2033532745","https://openalex.org/W2034217568","https://openalex.org/W2034744205","https://openalex.org/W2035120987","https://openalex.org/W2035635953","https://openalex.org/W2035881741","https://openalex.org/W2037876291","https://openalex.org/W2038451572","https://openalex.org/W2038538904","https://openalex.org/W2038871793","https://openalex.org/W2038932046","https://openalex.org/W2039144927","https://openalex.org/W2040321376","https://openalex.org/W2041803372","https://openalex.org/W2045368340","https://openalex.org/W2047127801","https://openalex.org/W2048843865","https://openalex.org/W2052791307","https://openalex.org/W2053167235","https://openalex.org/W2053559576","https://openalex.org/W2055186686","https://openalex.org/W2055330891","https://openalex.org/W2055409224","https://openalex.org/W2057127856","https://openalex.org/W2057500222","https://openalex.org/W2057763398","https://openalex.org/W2059247797","https://openalex.org/W2059478483","https://openalex.org/W2059991470","https://openalex.org/W2060387110","https://openalex.org/W2064062498","https://openalex.org/W2066341116","https://openalex.org/W2066398640","https://openalex.org/W2066561422","https://openalex.org/W2067697000","https://openalex.org/W2069600152","https://openalex.org/W2069906438","https://openalex.org/W2070407843","https://openalex.org/W2073095545","https://openalex.org/W2073450287","https://openalex.org/W2074581934","https://openalex.org/W2074974240","https://openalex.org/W2078142395","https://openalex.org/W2078789786","https://openalex.org/W2079788104","https://openalex.org/W2079906375","https://openalex.org/W2080798669","https://openalex.org/W2080937125","https://openalex.org/W2081470277","https://openalex.org/W2081950413","https://openalex.org/W2086046433","https://openalex.org/W2086512618","https://openalex.org/W2088435636","https://openalex.org/W2089284420","https://openalex.org/W2090675971","https://openalex.org/W2090848338","https://openalex.org/W2093603211","https://openalex.org/W2093882682","https://openalex.org/W2094025915","https://openalex.org/W2094212271","https://openalex.org/W2094222260","https://openalex.org/W2095024226","https://openalex.org/W2096065245","https://openalex.org/W2097289197","https://openalex.org/W2097627784","https://openalex.org/W2098095773","https://openalex.org/W2099633006","https://openalex.org/W2100400861","https://openalex.org/W2102052313","https://openalex.org/W2102630280","https://openalex.org/W2103187988","https://openalex.org/W2104240609","https://openalex.org/W2104479866","https://openalex.org/W2104576267","https://openalex.org/W2105420524","https://openalex.org/W2107532238","https://openalex.org/W2108441694","https://openalex.org/W2108676272","https://openalex.org/W2110117704","https://openalex.org/W2110513131","https://openalex.org/W2113031685","https://openalex.org/W2113787496","https://openalex.org/W2114263370","https://openalex.org/W2115183624","https://openalex.org/W2115767669","https://openalex.org/W2116470343","https://openalex.org/W2116939805","https://openalex.org/W2117041194","https://openalex.org/W2118069647","https://openalex.org/W2119288883","https://openalex.org/W2120315535","https://openalex.org/W2120553816","https://openalex.org/W2120632975","https://openalex.org/W2122395913","https://openalex.org/W2122737933","https://openalex.org/W2123066014","https://openalex.org/W2123227888","https://openalex.org/W2123721271","https://openalex.org/W2124030672","https://openalex.org/W2124140045","https://openalex.org/W2124275588","https://openalex.org/W2124483619","https://openalex.org/W2124607936","https://openalex.org/W2124921234","https://openalex.org/W2125300128","https://openalex.org/W2125624250","https://openalex.org/W2126920991","https://openalex.org/W2127522716","https://openalex.org/W2129038749","https://openalex.org/W2130359787","https://openalex.org/W2131970968","https://openalex.org/W2132178599","https://openalex.org/W2132251464","https://openalex.org/W2132569663","https://openalex.org/W2132764178","https://openalex.org/W2133663537","https://openalex.org/W2141599538","https://openalex.org/W2141718993","https://openalex.org/W2142614171","https://openalex.org/W2142658562","https://openalex.org/W2144275955","https://openalex.org/W2144846851","https://openalex.org/W2145593944","https://openalex.org/W2146376811","https://openalex.org/W2148751141","https://openalex.org/W2149000483","https://openalex.org/W2150020215","https://openalex.org/W2150473092","https://openalex.org/W2151485619","https://openalex.org/W2153442585","https://openalex.org/W2156101477","https://openalex.org/W2156538971","https://openalex.org/W2157680277","https://openalex.org/W2158730778","https://openalex.org/W2159269771","https://openalex.org/W2160066987","https://openalex.org/W2162257366","https://openalex.org/W2163991860","https://openalex.org/W2164174765","https://openalex.org/W2164891280","https://openalex.org/W2164938051","https://openalex.org/W2165406466","https://openalex.org/W2167269773","https://openalex.org/W2172231976","https://openalex.org/W2182058935","https://openalex.org/W2185307487","https://openalex.org/W2316816410","https://openalex.org/W2394552110","https://openalex.org/W2401884873","https://openalex.org/W2406556971"],"related_works":["https://openalex.org/W2120866904","https://openalex.org/W2002276332","https://openalex.org/W2132569663","https://openalex.org/W2098095773","https://openalex.org/W3169094737","https://openalex.org/W2105420524","https://openalex.org/W1978000687","https://openalex.org/W7217953583","https://openalex.org/W7096891807","https://openalex.org/W2809215646"],"abstract_inverted_index":{"Regulering":[0],"av":[1,7,16,23,113,142,153,175],"PP1":[2],"og":[3,9,32,57,71,85,164],"Nuklein":[4],"syre":[5,49],"binding":[6],"AKAP149":[8,114,134,170],"PNUTS.":[10],"\\n\\nDet":[11],"er":[12,81,96,118,123,149],"estimert":[13],"at":[14,78,99,108,133,151],"1":[15],"8,000":[17],"har":[18,178],"en":[19,38,110],"sykdom":[20],"som":[21,26,54,80,161,171],"konsekvens":[22],"induserte":[24,143],"mutasjoner":[25,144,168],"p\u00e5virker":[27],"mitokondrienes":[28,47],"funksjon":[29],"eller":[30,128],"prosesser,":[31],"mitokondriell":[33],"dysfunksjon":[34,56],"blir":[35],"implikert":[36],"i":[37,46,66,83,94,105,126,145,169,181],"voksende":[39],"mengde":[40],"sykdommer.":[41],"For":[42],"eksempel":[43],"kan":[44,156],"feil":[45],"fett":[48],"oksidering":[50],"f\u00f8re":[51,157],"til":[52,137,158,173],"sykdommer":[53,160,183],"lever":[55],"kardiomyopati,":[58],"blant":[59],"flere.":[60],"Mitokondriene":[61],"spiller":[62],"ogs\u00e5":[63],"essensielle":[64],"roller":[65],"naturlig":[67],"aldring,":[68],"virus":[69],"infeksjon":[70],"forbrenning.":[72],"\\n\\nI":[73],"dette":[74],"doktorarbeidet":[75],"viser":[76],"vi":[77],"AKAP149,":[79],"lokalisert":[82],"mitokondriene":[84,100,122],"binder":[86],"flere":[87],"proteiner":[88],"kjent":[89,150],"for":[90,98,120],"\u00e5":[91],"v\u00e6re":[92,102],"viktig":[93,97],"signalkaskader,":[95],"skal":[101],"plassert":[103],"riktig":[104],"cellene.":[106],"Videre":[107],"det":[109],"konservert":[111],"del":[112],"-":[115],"KH":[116,146],"domenet":[117],"ansvarlig":[119],"om":[121,167],"fint":[124],"distribuert":[125],"nettverk":[127],"kollapser.":[129],"Dette":[130],"trolig":[131],"ved":[132],"mister":[135],"evnen":[136],"binde":[138],"RNA":[139],"p\u00e5":[140],"grunn":[141],"domenet.":[147],"Det":[148],"kollaps":[152,174],"mitokondrie":[154,176],"nettverket":[155,177],"neurdegenerative":[159],"Alzheimer,":[162],"Parkinson":[163],"ASL.":[165],"Sp\u00f8rsm\u00e5let":[166],"f\u00f8rer":[172],"noen":[179],"rolle":[180],"neurodegenerative":[182],"gjenst\u00e5r":[184],"per":[185],"dags":[186],"dato.":[187]},"counts_by_year":[],"updated_date":"2026-09-03T10:48:47.769340","created_date":"2016-06-24T00:00:00"}
