{"id":"https://openalex.org/W2401493665","doi":null,"title":"Hypothalamic control of water and salt intake and excretion.","display_name":"Hypothalamic control of water and salt intake and excretion.","publication_year":1994,"publication_date":"1994-04-01","ids":{"openalex":"https://openalex.org/W2401493665","mag":"2401493665","pmid":"https://pubmed.ncbi.nlm.nih.gov/8087092"},"language":"en","primary_location":{"id":"pmid:8087092","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8087092","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069185819","display_name":"Samuel M. McCann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S M McCann","raw_affiliation_strings":["Department of Physiology, University of Texas Southwestern Medical Center at Dallas 75235-8873"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, University of Texas Southwestern Medical Center at Dallas 75235-8873","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074332001","display_name":"Jolanta Gutkowska","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Gutkowska","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109933704","display_name":"Celso Rodrigues Franci","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C R Franci","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011605651","display_name":"A L Favaretto","orcid":"https://orcid.org/0000-0002-6359-7110","observed_orcids":["https://orcid.org/0000-0002-6359-7110"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A L Favaretto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5067009357","display_name":"Jos\u00e9 Antunes\u2010Rodrigues","orcid":"https://orcid.org/0000-0003-3486-9217","observed_orcids":["https://orcid.org/0000-0003-3486-9217"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Antunes-Rodrigues","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2072,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.81238993,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"27","issue":"4","first_page":"865","last_page":"84"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.24709999561309814,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.24709999561309814,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11967","display_name":"Electrolyte and hormonal disorders","score":0.23909999430179596,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.19519999623298645,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.9879999756813049},{"id":"https://openalex.org/keywords/water-intake","display_name":"water intake","score":0.7910000085830688},{"id":"https://openalex.org/keywords/salt-intake","display_name":"salt intake","score":0.8849999904632568},{"id":"https://openalex.org/keywords/salt-excretion","display_name":"salt excretion","score":0.8080000281333923},{"id":"https://openalex.org/keywords/thirst","display_name":"thirst","score":0.875},{"id":"https://openalex.org/keywords/atrial-natriuretic-peptide","display_name":"atrial natriuretic peptide","score":0.9580000042915344},{"id":"https://openalex.org/keywords/osmotic-stimulation","display_name":"osmotic stimulation","score":0.7160000205039978},{"id":"https://openalex.org/keywords/cholinergic-stimulation","display_name":"cholinergic stimulation","score":0.8159999847412109},{"id":"https://openalex.org/keywords/alpha-adrenergic-stimulation","display_name":"alpha-adrenergic stimulation","score":0.9860000014305115},{"id":"https://openalex.org/keywords/volume-expansion","display_name":"volume expansion","score":0.906000018119812},{"id":"https://openalex.org/keywords/neuroendocrine-regulation","display_name":"neuroendocrine regulation","score":0.8109999895095825},{"id":"https://openalex.org/keywords/research-history","display_name":"history of research","score":0.5509999990463257}],"concepts":[{"id":"https://openalex.org/C2777003273","wikidata":"https://www.wikidata.org/wiki/Q164386","display_name":"Hypothalamus","level":2,"score":0.7600307464599609},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6810685992240906},{"id":"https://openalex.org/C2778713406","wikidata":"https://www.wikidata.org/wiki/Q474187","display_name":"Thirst","level":2,"score":0.6640906929969788},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6518515348434448},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.5597864389419556},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.5498834848403931},{"id":"https://openalex.org/C79752029","wikidata":"https://www.wikidata.org/wiki/Q808732","display_name":"Baroreceptor","level":4,"score":0.5459930896759033},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4998157024383545},{"id":"https://openalex.org/C133944241","wikidata":"https://www.wikidata.org/wiki/Q904232","display_name":"Osmoreceptor","level":3,"score":0.4995865821838379},{"id":"https://openalex.org/C22885893","wikidata":"https://www.wikidata.org/wiki/Q4862743","display_name":"Cholinergic","level":2,"score":0.4588921368122101},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3522242307662964},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33863264322280884},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.1883562207221985},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.17295333743095398}],"mesh":[{"descriptor_ui":"D000804","descriptor_name":"Angiotensin II","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000804","descriptor_name":"Angiotensin II","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002415","descriptor_name":"Cats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004326","descriptor_name":"Drinking","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006041","descriptor_name":"Goats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007031","descriptor_name":"Hypothalamus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009074","descriptor_name":"Melanocyte-Stimulating Hormones","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009318","descriptor_name":"Natriuresis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009320","descriptor_name":"Atrial Natriuretic Factor","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D010121","descriptor_name":"Oxytocin","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012462","descriptor_name":"Saline Solution, Hypertonic","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014667","descriptor_name":"Vasopressins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D014882","descriptor_name":"Water-Electrolyte Balance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8087092","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8087092","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica","raw_type":"Journal Article"},{"id":"mag:2401493665","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8087092","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2151319526","https://openalex.org/W2322650728","https://openalex.org/W2055780253","https://openalex.org/W2148232586","https://openalex.org/W1570636972","https://openalex.org/W13922854","https://openalex.org/W2090936211","https://openalex.org/W2071748077","https://openalex.org/W2024055501","https://openalex.org/W2301585111"],"abstract_inverted_index":{"This":[0],"article":[1],"provides":[2],"a":[3],"personal":[4],"and":[5,16,19,33,59,81,84],"historical":[6],"review":[7],"of":[8,14,36,41,52,57,65,77,82,90,94,98],"research":[9],"concerning":[10],"the":[11,37,42,55,66,88,99],"hypothalamic":[12,78],"control":[13,56],"water":[15],"salt":[17,60],"intake":[18],"excretion.":[20,61],"The":[21,50,63,75],"following":[22],"major":[23],"points":[24],"will":[25],"be":[26],"considered:":[27],"1.":[28],"Electrical,":[29],"osmotic,":[30],"cholinergic,":[31],"alpha-adrenergic":[32],"peptidergic":[34],"stimulation":[35],"hypothalamus.":[38],"2.":[39],"Determination":[40],"pathways":[43],"involved":[44],"in":[45,54,71,87],"these":[46],"neuroendocrine":[47],"responses.":[48],"3.":[49],"participation":[51,64],"ANP":[53,72,101],"thirst":[58],"4.":[62],"brain":[67,100],"ANPergic":[68,79],"neuronal":[69],"system":[70,102],"release.":[73],"5.":[74],"role":[76],"neurons":[80],"sinoaortic":[83],"renal":[85],"baroreceptors":[86],"regulation":[89],"volume":[91],"expansion-induced":[92],"release":[93],"ANP.":[95],"6.":[96],"Effects":[97],"on":[103],"other":[104],"hormones.":[105]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}