{"id":"https://openalex.org/W2401087948","doi":null,"title":"Gene mapping and identification for osteoporosis.","display_name":"Gene mapping and identification for osteoporosis.","publication_year":2004,"publication_date":"2004-03-01","ids":{"openalex":"https://openalex.org/W2401087948","mag":"2401087948","pmid":"https://pubmed.ncbi.nlm.nih.gov/15615082"},"language":"en","primary_location":{"id":"pmid:15615082","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15615082","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024194480","display_name":"Hong\u2010Wen Deng","orcid":"https://orcid.org/0000-0002-0387-8818","observed_orcids":["https://orcid.org/0000-0002-0387-8818","https://orcid.org/0000-0003-1933-7095"]},"institutions":[{"id":"https://openalex.org/I114493937","display_name":"Creighton University","ror":"https://ror.org/05wf30g94","country_code":"US","type":"education","lineage":["https://openalex.org/I114493937"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H W Deng","raw_affiliation_strings":["Osteoporosis Research Center, Creighton University, Omaha, NE 68131, USA deng@creighton.edu","Osteoporosis Research Center, Creighton University, Omaha, NE 68131, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, NE 68131, USA deng@creighton.edu","institution_ids":["https://openalex.org/I114493937"]},{"raw_affiliation_string":"Osteoporosis Research Center, Creighton University, Omaha, NE 68131, USA","institution_ids":["https://openalex.org/I114493937"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052478195","display_name":"Robert R. Recker","orcid":"https://orcid.org/0000-0002-8774-1404","observed_orcids":["https://orcid.org/0000-0002-8774-1404"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R R Recker","raw_affiliation_strings":["Department of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6451,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.77184796,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"4","issue":"1","first_page":"91","last_page":"100"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.8889999985694885},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.6499999761581421},{"id":"https://openalex.org/keywords/genetic-mapping","display_name":"gene mapping","score":0.824999988079071},{"id":"https://openalex.org/keywords/mode-of-inheritance","display_name":"mode of inheritance","score":0.6740000247955322},{"id":"https://openalex.org/keywords/complex-traits","display_name":"complex traits","score":0.8180000185966492},{"id":"https://openalex.org/keywords/genetic-factors","display_name":"genetic factors","score":0.5699999928474426},{"id":"https://openalex.org/keywords/chinese-population","display_name":"Chinese population","score":0.5040000081062317},{"id":"https://openalex.org/keywords/white-population","display_name":"Caucasian population","score":0.6909999847412109},{"id":"https://openalex.org/keywords/older-women","display_name":"older women","score":0.5920000076293945}],"concepts":[{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.8463899493217468},{"id":"https://openalex.org/C2780902518","wikidata":"https://www.wikidata.org/wiki/Q6033780","display_name":"Inheritance (genetic algorithm)","level":3,"score":0.6462703347206116},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.583435595035553},{"id":"https://openalex.org/C106934330","wikidata":"https://www.wikidata.org/wiki/Q1971873","display_name":"Trait","level":2,"score":0.5559346675872803},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.5303621292114258},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5221372246742249},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.4962502121925354},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4441972076892853},{"id":"https://openalex.org/C64474127","wikidata":"https://www.wikidata.org/wiki/Q1071953","display_name":"Medical genetics","level":3,"score":0.4221261143684387},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.35361284017562866},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3461291790008545},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.32883310317993164},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32613205909729004},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29196682572364807},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.20911502838134766},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1884250044822693},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.11903956532478333},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015519","descriptor_name":"Bone Density","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":true},{"descriptor_ui":"D040582","descriptor_name":"Inheritance Patterns","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D044465","descriptor_name":"White People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000208","qualifier_name":"ethnology","is_major_topic":false},{"descriptor_ui":"D050723","descriptor_name":"Fractures, Bone","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:15615082","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15615082","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of musculoskeletal & neuronal interactions","raw_type":"Journal Article"},{"id":"mag:2401087948","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15615082","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6064384742","display_name":"CHARACTERIZATION OF DELETERIOUS GENOMIC MUTATIONS","funder_award_id":"R01GM060402","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G749568872","display_name":"Genetic Basis of Osteoporotic Fractures and Bone Mass","funder_award_id":"K01AR002170","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1543868019","https://openalex.org/W1547202054","https://openalex.org/W1560012080","https://openalex.org/W1577972870","https://openalex.org/W1924613311","https://openalex.org/W1963936426","https://openalex.org/W1967053372","https://openalex.org/W1968112125","https://openalex.org/W1970093445","https://openalex.org/W1974727020","https://openalex.org/W1975244016","https://openalex.org/W1979979725","https://openalex.org/W1984941837","https://openalex.org/W1987691142","https://openalex.org/W1987946394","https://openalex.org/W1992681542","https://openalex.org/W1996414183","https://openalex.org/W2000324791","https://openalex.org/W2003738104","https://openalex.org/W2008178459","https://openalex.org/W2009318451","https://openalex.org/W2010018635","https://openalex.org/W2010929467","https://openalex.org/W2012348136","https://openalex.org/W2022776726","https://openalex.org/W2025155191","https://openalex.org/W2028355948","https://openalex.org/W2030165415","https://openalex.org/W2033242206","https://openalex.org/W2038202912","https://openalex.org/W2040156285","https://openalex.org/W2040645421","https://openalex.org/W2042103448","https://openalex.org/W2043745529","https://openalex.org/W2044205790","https://openalex.org/W2069635031","https://openalex.org/W2080361330","https://openalex.org/W2082215747","https://openalex.org/W2083530199","https://openalex.org/W2089080975","https://openalex.org/W2096051150","https://openalex.org/W2099996412","https://openalex.org/W2107887211","https://openalex.org/W2108262726","https://openalex.org/W2113686392","https://openalex.org/W2114243671","https://openalex.org/W2114575674","https://openalex.org/W2130472330","https://openalex.org/W2140912694","https://openalex.org/W2142198096","https://openalex.org/W2147789998","https://openalex.org/W2159047154","https://openalex.org/W2159368597","https://openalex.org/W2165167367","https://openalex.org/W2170971961","https://openalex.org/W2227909353","https://openalex.org/W2323830513"],"related_works":["https://openalex.org/W2028355948","https://openalex.org/W2133377516","https://openalex.org/W2030239246","https://openalex.org/W2069464777","https://openalex.org/W3023990279","https://openalex.org/W765212907","https://openalex.org/W1994948620","https://openalex.org/W2010018635","https://openalex.org/W2162765748","https://openalex.org/W3030424154"],"abstract_inverted_index":{"Osteoporosis":[0],"is":[1,16,97],"a":[2,17,79],"disease":[3],"characterized":[4],"by":[5],"fragile":[6],"bones":[7],"and":[8,39,54,61,71,87,105],"high":[9],"susceptibility":[10],"to":[11,56,98,100,111],"low":[12],"trauma":[13],"fractures.":[14],"It":[15],"serious":[18],"health":[19],"problem,":[20],"especially":[21],"in":[22,51],"elderly":[23],"women.":[24],"Bone":[25],"mineral":[26],"density":[27],"(BMD)":[28],"has":[29],"been":[30],"employed":[31],"most":[32],"commonly":[33],"as":[34,83],"the":[35,58,69,72,95,101,113,121],"index":[36],"for":[37,90,124],"defining":[38],"studying":[40],"osteoporosis.":[41,91],"In":[42],"this":[43],"presentation,":[44],"we":[45],"use":[46],"examples":[47],"of":[48,75,78,94,115,118],"our":[49],"studies":[50],"both":[52],"Caucasians":[53],"Chinese":[55],"illustrate":[57],"approaches":[59],"used":[60],"some":[62],"main":[63],"results":[64],"obtained":[65],"on":[66],"1)":[67],"characterizing":[68],"degree":[70],"inheritance":[73],"mode":[74],"genetic":[76],"determination":[77],"complex":[80],"trait":[81],"such":[82],"BMD;":[84],"2)":[85],"identifying":[86],"mapping":[88],"genes":[89],"The":[92],"purpose":[93],"presentation":[96],"introduce":[99],"medical":[102],"researchers":[103],"how":[104],"what":[106],"modern":[107],"genetics":[108,119],"can":[109],"do":[110],"disentangle":[112],"mist":[114],"an":[116],"array":[117],"factors,":[120],"major":[122],"determinants,":[123],"BMD.":[125]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}