{"id":"https://openalex.org/W2400575010","doi":null,"title":"[T lymphocytes functions in mercuric chloride-induced membranous glomerulonephritis in man. Evidence for a defect of presentation of the histocompatibility class II molecules at the cell surface (author's transl)].","display_name":"[T lymphocytes functions in mercuric chloride-induced membranous glomerulonephritis in man. Evidence for a defect of presentation of the histocompatibility class II molecules at the cell surface (author's transl)].","publication_year":1981,"publication_date":"1981-01-01","ids":{"openalex":"https://openalex.org/W2400575010","mag":"2400575010","pmid":"https://pubmed.ncbi.nlm.nih.gov/6460199"},"language":"fr","primary_location":{"id":"pmid:6460199","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6460199","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrologie","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056349922","display_name":"B Charpentier","orcid":"https://orcid.org/0000-0001-8855-5884","observed_orcids":["https://orcid.org/0000-0001-8855-5884"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Charpentier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080206249","display_name":"Ph. Moullot","orcid":"https://orcid.org/0000-0002-1905-678X","observed_orcids":["https://orcid.org/0000-0002-1905-678X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Moullot","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"N Faux","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Faux","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060759611","display_name":"G Manigand","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Manigand","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5056971117","display_name":"Dietmar R. Fries","orcid":"https://orcid.org/0000-0002-1225-4214","observed_orcids":["https://orcid.org/0000-0002-1225-4214"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Fries","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0399,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.76812765,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"2","issue":"4","first_page":"153","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.6104000210762024,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.6104000210762024,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.2703000009059906,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.038600001484155655,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/membranous-nephropathy","display_name":"membranous nephropathy","score":0.9860000014305115},{"id":"https://openalex.org/keywords/mercuric-chloride","display_name":"mercuric chloride","score":0.8579999804496765},{"id":"https://openalex.org/keywords/mercury-intoxication","display_name":"mercury intoxication","score":0.8410000205039978},{"id":"https://openalex.org/keywords/t-lymphocyte-function","display_name":"T lymphocyte function","score":0.8299999833106995},{"id":"https://openalex.org/keywords/hla-dr","display_name":"HLA-DR","score":0.7720000147819519},{"id":"https://openalex.org/keywords/lymphocyte-transformation","display_name":"lymphocyte transformation","score":0.8140000104904175},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.7559999823570251},{"id":"https://openalex.org/keywords/lymphocyte-abnormalities","display_name":"lymphocyte abnormalities","score":0.4269999861717224}],"concepts":[{"id":"https://openalex.org/C2780368995","wikidata":"https://www.wikidata.org/wiki/Q605006","display_name":"Glomerulonephritis","level":3,"score":0.7134612202644348},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.692073404788971},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6536059379577637},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.5850858688354492},{"id":"https://openalex.org/C2776115139","wikidata":"https://www.wikidata.org/wiki/Q1753456","display_name":"Glomerular basement membrane","level":4,"score":0.5786551237106323},{"id":"https://openalex.org/C2992881475","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T lymphocyte","level":3,"score":0.5521902441978455},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.47096186876296997},{"id":"https://openalex.org/C202965653","wikidata":"https://www.wikidata.org/wiki/Q2664028","display_name":"Histocompatibility","level":4,"score":0.46767792105674744},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.4116595685482025},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.4113152325153351},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3864244520664215},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.37696802616119385},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.31303101778030396},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.24673256278038025},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2383832335472107}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000936","descriptor_name":"Antigen-Antibody Complex","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D001323","descriptor_name":"Autoantibodies","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005921","descriptor_name":"Glomerulonephritis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D005921","descriptor_name":"Glomerulonephritis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006649","descriptor_name":"Histocompatibility Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008627","descriptor_name":"Mercuric Chloride","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008628","descriptor_name":"Mercury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008630","descriptor_name":"Mercury Poisoning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012397","descriptor_name":"Rosette Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:6460199","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6460199","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nephrologie","raw_type":"Case Reports"},{"id":"mag:2400575010","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6460199","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1459783841","https://openalex.org/W7131913094","https://openalex.org/W1937050720","https://openalex.org/W2018365821","https://openalex.org/W2043528848","https://openalex.org/W2001825901","https://openalex.org/W1637791168","https://openalex.org/W2007049260","https://openalex.org/W7132545153","https://openalex.org/W2044843571"],"abstract_inverted_index":{"Membranous":[0],"glomerulonephritis":[1],"(MGN)":[2],"is":[3],"one":[4,71],"of":[5,10,24,54,87,91,101,126,145,152,156],"the":[6,25,44,88,99,109,114,124,150],"well":[7],"documented":[8],"manifestations":[9],"autoimmunity":[11],"during":[12],"chronic":[13],"mercuric":[14],"chloride":[15],"(HgCl2)":[16],"intoxication.":[17],"We":[18],"have":[19],"carried":[20],"out":[21],"immunological":[22],"investigation":[23],"T":[26],"cell":[27,110],"functions":[28],"in":[29,123,130,139],"a":[30,51,70,84,153,162],"patient":[31],"presenting":[32],"an":[33,127],"HgC12-induced":[34],"MGN.":[35],"Circulating":[36],"auto-antibodies":[37],"and":[38,112],"immune":[39],"complexes":[40],"were":[41],"absent":[42],"from":[43],"serum.":[45],"Lymphocyte":[46],"transformation":[47],"with":[48,83,135],"HgCl2":[49],"over":[50],"wide":[52],"range":[53],"doses":[55],"(10(-3)":[56],"to":[57,98,105],"10(-8)":[58],"M)":[59],"was":[60],"negative.":[61],"E":[62],"rosettes,":[63],"mitogen":[64],"reactivity,":[65],"allogeneic":[66,115],"reactivity":[67],"evidenced":[68],"by":[69,117],"way":[72],"mixed":[73],"lymphocyte":[74,121,136,159],"culture":[75],"gave":[76],"slightly":[77],"diminished":[78],"results.":[79],"These":[80],"findings":[81],"contrasted":[82],"severe":[85],"impairment":[86],"stimulative":[89],"ability":[90],"lymphocytes.":[92,119],"This":[93,120],"defect":[94,122],"might":[95],"be":[96,106,133],"related":[97],"inability":[100],"D,":[102],"DR":[103],"products":[104],"exposed":[107],"at":[108],"surface":[111],"impeding":[113],"recognition":[116],"foreign":[118],"course":[125],"HgC12":[128,157],"MGN":[129],"man":[131],"would":[132,148],"correlated":[134],"abnormalities":[137],"found":[138],"experimental":[140],"HgC12-treated":[141],"rats.":[142],"The":[143],"results":[144],"this":[146],"study":[147],"favour":[149],"hypothesis":[151],"direct":[154,163],"role":[155],"on":[158,165],"rather":[160],"than":[161],"action":[164],"glomerular":[166],"basement":[167],"membrane.":[168]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}