{"id":"https://openalex.org/W2399845239","doi":null,"title":"High plasma cholecystokinin levels in patients with chronic pancreatitis having abdominal pain.","display_name":"High plasma cholecystokinin levels in patients with chronic pancreatitis having abdominal pain.","publication_year":1986,"publication_date":"1986-12-01","ids":{"openalex":"https://openalex.org/W2399845239","mag":"2399845239","pmid":"https://pubmed.ncbi.nlm.nih.gov/3538853"},"language":"en","primary_location":{"id":"pmid:3538853","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3538853","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055281656","display_name":"A Funakoshi","orcid":"https://orcid.org/0000-0003-0383-8901","observed_orcids":["https://orcid.org/0000-0003-0383-8901"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Funakoshi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071232863","display_name":"Itsuro Nakano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Nakano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112134817","display_name":"Hidehiro Shinozaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Shinozaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"K Tateishi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Tateishi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076624164","display_name":"Takafumi Hamaoka","orcid":"https://orcid.org/0000-0002-7470-5711","observed_orcids":["https://orcid.org/0000-0002-7470-5711"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Hamaoka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100844751","display_name":"Hiroshi Ibayashi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Ibayashi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1694,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.885119,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"81","issue":"12","first_page":"1174","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.02019999921321869,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cholecystokinin","display_name":"cholecystokinin","score":0.9800000190734863},{"id":"https://openalex.org/keywords/chronic-pancreatitis","display_name":"chronic pancreatitis","score":0.9380000233650208},{"id":"https://openalex.org/keywords/abdominal-pain","display_name":"abdominal pain","score":0.9629999995231628},{"id":"https://openalex.org/keywords/plasma-cck-levels","display_name":"plasma CCK levels","score":0.8650000095367432},{"id":"https://openalex.org/keywords/exocrine-pancreatic-insufficiency","display_name":"exocrine pancreatic insufficiency","score":0.7009999752044678},{"id":"https://openalex.org/keywords/cck-8","display_name":"CCK-8","score":0.6710000038146973},{"id":"https://openalex.org/keywords/immunization-procedures","display_name":"immunization procedures","score":0.7390000224113464}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9097557067871094},{"id":"https://openalex.org/C2777593968","wikidata":"https://www.wikidata.org/wiki/Q60315441","display_name":"Cholecystokinin","level":3,"score":0.8849321007728577},{"id":"https://openalex.org/C2775967933","wikidata":"https://www.wikidata.org/wiki/Q1527888","display_name":"Pancreatitis","level":2,"score":0.7924537062644958},{"id":"https://openalex.org/C193230392","wikidata":"https://www.wikidata.org/wiki/Q1663054","display_name":"Ingestion","level":2,"score":0.7703473567962646},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.6917763948440552},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6819801926612854},{"id":"https://openalex.org/C2780955771","wikidata":"https://www.wikidata.org/wiki/Q183425","display_name":"Abdominal pain","level":2,"score":0.6281958222389221},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5259737372398376},{"id":"https://openalex.org/C110586980","wikidata":"https://www.wikidata.org/wiki/Q4168588","display_name":"Provocation test","level":3,"score":0.5229262113571167},{"id":"https://openalex.org/C2778345441","wikidata":"https://www.wikidata.org/wiki/Q6460735","display_name":"Meal","level":2,"score":0.5223948955535889},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4766564965248108},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08820375800132751},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000005","descriptor_name":"Abdomen","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002766","descriptor_name":"Cholecystokinin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005215","descriptor_name":"Fasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005246","descriptor_name":"Feedback","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005502","descriptor_name":"Food","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010146","descriptor_name":"Pain","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D010179","descriptor_name":"Pancreas","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010182","descriptor_name":"Pancreatic Diseases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010182","descriptor_name":"Pancreatic Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D010191","descriptor_name":"Pancreatic Polypeptide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3538853","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3538853","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of gastroenterology","raw_type":"Journal Article"},{"id":"mag:2399845239","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3538853","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2028646460","https://openalex.org/W2409088527","https://openalex.org/W2343592039","https://openalex.org/W2062081592","https://openalex.org/W2074409059","https://openalex.org/W2059195942","https://openalex.org/W2004061807","https://openalex.org/W2423530250","https://openalex.org/W149983397","https://openalex.org/W7097509809"],"abstract_inverted_index":{"Plasma":[0],"cholecystokinin":[1],"(CCK)":[2],"responses":[3],"after":[4],"ingestion":[5,81],"of":[6,38,82,91],"a":[7,22,32,47,83,89],"test":[8,85],"meal":[9,86],"in":[10,54,115],"patients":[11,56],"with":[12,21,63],"mild":[13,59],"chronic":[14],"pancreatitis":[15],"having":[16],"abdominal":[17],"pain":[18],"were":[19],"studied":[20],"radioimmunoassay":[23],"using":[24,44],"the":[25,39,80,100],"CCK":[26,42,103],"specific":[27],"antiserum":[28],"(OAL-656)":[29],"produced":[30],"by":[31],"novel":[33],"immunization":[34],"procedure.":[35],"Mean":[36],"concentration":[37],"fasting":[40],"plasma":[41],"determined":[43],"CCK-8":[45],"as":[46],"standard":[48],"was":[49,66,111],"31.5":[50],"+/-":[51,74,93,106,119],"5.8":[52],"pg/ml":[53,95],"six":[55],"who":[57],"had":[58],"impaired":[60],"exocrine":[61],"function":[62],"pain,":[64],"and":[65,99],"significantly":[67,112],"higher":[68,113],"than":[69,114],"10":[70],"healthy":[71,116],"subjects":[72,117],"(9.8":[73],"1.8":[75],"pg/ml).":[76],"In":[77],"those":[78],"patients,":[79],"liquid":[84],"led":[87],"to":[88],"peak":[90],"75.1":[92],"25.4":[94],"at":[96],"30":[97],"min,":[98],"120-min":[101],"integrated":[102],"response":[104],"(5427":[105],"1217.3":[107],"pg":[108,121],"X":[109,122],"min/ml)":[110],"(1538":[118],"110.1":[120],"min/ml).":[123]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}