{"id":"https://openalex.org/W2399172003","doi":null,"title":"Noncontraceptive estrogens and mortality: long-term follow-up of women in the Walnut Creek Study.","display_name":"Noncontraceptive estrogens and mortality: long-term follow-up of women in the Walnut Creek Study.","publication_year":1987,"publication_date":"1987-09-01","ids":{"openalex":"https://openalex.org/W2399172003","mag":"2399172003","pmid":"https://pubmed.ncbi.nlm.nih.gov/3627576"},"language":"en","primary_location":{"id":"pmid:3627576","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3627576","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Comparative Study"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036313495","display_name":"D B Petitti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D B Petitti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110158065","display_name":"Jeffrey A. Perlman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J A Perlman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5005123548","display_name":"Stephen Sidney","orcid":"https://orcid.org/0009-0008-4556-6426","observed_orcids":["https://orcid.org/0009-0008-4556-6426"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Sidney","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.7966,"has_fulltext":false,"cited_by_count":178,"citation_normalized_percentile":{"value":0.95722049,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"70","issue":"3 Pt 1","first_page":"289","last_page":"93"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postmenopausal-estrogen-therapy","display_name":"postmenopausal estrogen therapy","score":0.7879999876022339},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.9559999704360962},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.8560000061988831},{"id":"https://openalex.org/keywords/lifestyle-differences","display_name":"lifestyle differences","score":0.7580000162124634},{"id":"https://openalex.org/keywords/cancer-mortality","display_name":"cancer mortality","score":0.6549999713897705},{"id":"https://openalex.org/keywords/women","display_name":"women","score":0.3709999918937683}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.927452802658081},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.7517561912536621},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4964295029640198},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.446478933095932},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.4384484589099884},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.4377535581588745},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.379725843667984},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2289104461669922},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.08787548542022705},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002140","descriptor_name":"California","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003276","descriptor_name":"Contraceptives, Oral","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008593","descriptor_name":"Menopause","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009026","descriptor_name":"Mortality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012306","descriptor_name":"Risk","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3627576","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3627576","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Comparative Study"},{"id":"mag:2399172003","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3627576","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8799999952316284,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G988150360","display_name":"STEROID CONTRACEPTIVES IN HEPATOBILIARY DISEASE","funder_award_id":"n01hd042817-001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2317040757","https://openalex.org/W1911947301","https://openalex.org/W3140335276","https://openalex.org/W2011247197","https://openalex.org/W1974523009","https://openalex.org/W2054313225","https://openalex.org/W4236550027","https://openalex.org/W2051028982","https://openalex.org/W2140782377","https://openalex.org/W1994349098"],"abstract_inverted_index":{"The":[0,98],"effect":[1],"of":[2,27,92,94,145],"postmenopausal":[3],"estrogen":[4,61,74,107,122,154],"use":[5],"on":[6],"mortality":[7,25,72,100,146],"is":[8,166],"an":[9],"important":[10],"and":[11,47,63,104,114,124,160],"controversial":[12],"subject.":[13],"To":[14],"address":[15],"it,":[16],"we":[17],"analyzed":[18],"data":[19],"from":[20,101],"a":[21],"ten-":[22],"to":[23,148],"13-year":[24],"follow-up":[26],"the":[28,33,48,115,136,139,142],"3437":[29],"women":[30,50],"enrolled":[31],"in":[32,73,83,106,129,153],"Walnut":[34],"Creek":[35],"Contraceptive":[36],"Drug":[37],"Study":[38],"who":[39,51],"never":[40],"used":[41,52],"either":[42],"estrogens":[43,53],"or":[44],"oral":[45,56],"contraceptives":[46],"2656":[49],"but":[54],"not":[55],"contraceptives.":[57],"By":[58],"1983,":[59],"109":[60],"users":[62,75,108,123],"110":[64],"nonusers":[65,84,125],"had":[66],"died.":[67],"After":[68],"adjusting":[69],"for":[70,89,131,158],"age,":[71],"(1.64":[76],"per":[77,86],"1000":[78,87],"woman-years)":[79,88],"was":[80,151],"lower":[81,99,133],"than":[82],"(2.06":[85],"all":[90],"categories":[91],"cause":[93],"death":[95],"except":[96],"cancer.":[97],"accidents,":[102],"suicide,":[103],"homicide":[105],"has":[109],"no":[110],"plausible":[111],"biologic":[112],"explanation,":[113],"observation":[116,140],"suggests":[117],"that":[118,141],"life-style":[119],"differences":[120],"between":[121],"account":[126],"at":[127],"least":[128],"part":[130],"their":[132],"mortality.":[134],"On":[135],"other":[137,161],"hand,":[138],"relative":[143],"risk":[144,164],"due":[147],"cardiovascular":[149,162],"disease":[150,163],"0.5":[152],"users,":[155],"after":[156],"adjustment":[157],"age":[159],"factors,":[165],"suggestive.":[167]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}