{"id":"https://openalex.org/W2398878641","doi":"https://doi.org/10.1159/000442802","title":"New Findings in Diabetic Maculopathy and Proliferative Disease by Swept-Source Optical Coherence Tomography Angiography","display_name":"New Findings in Diabetic Maculopathy and Proliferative Disease by Swept-Source Optical Coherence Tomography Angiography","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2398878641","doi":"https://doi.org/10.1159/000442802","mag":"2398878641","pmid":"https://pubmed.ncbi.nlm.nih.gov/27023703"},"language":"en","primary_location":{"id":"doi:10.1159/000442802","doi":"https://doi.org/10.1159/000442802","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000442802","pdf_url":null,"source":{"id":"https://openalex.org/S2755539230","display_name":"Developments in ophthalmology","issn_l":"0250-3751","issn":["0250-3751","1662-2790"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developments in Ophthalmology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2489256143","display_name":"OCT Angiography in Retinal and Macular Diseases"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054691770","display_name":"Paulo Eduardo Stanga","orcid":"https://orcid.org/0000-0002-3338-2055","observed_orcids":["https://orcid.org/0000-0002-3338-2055","https://orcid.org/0000-0001-6045-7895"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paulo E. Stanga","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027184718","display_name":"Alessandro Papayannis","orcid":"https://orcid.org/0000-0002-4876-7433","observed_orcids":["https://orcid.org/0000-0002-4876-7433"]},"institutions":[{"id":"https://openalex.org/I2801704036","display_name":"Manchester Royal Eye Hospital","ror":"https://ror.org/04xtpk854","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801704036","https://openalex.org/I4210092852","https://openalex.org/I4210166818"]},{"id":"https://openalex.org/I4405271435","display_name":"NIHR Manchester Clinical Research Facility","ror":"https://ror.org/02e706q76","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4405271435"]},{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alessandro Papayannis","raw_affiliation_strings":["Manchester Vision Regeneration (MVR) Lab at Manchester Royal Eye Hospital & NIHR/Wellcome Trust Manchester CRF, Manchester,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Vision Regeneration (MVR) Lab at Manchester Royal Eye Hospital & NIHR/Wellcome Trust Manchester CRF, Manchester,","institution_ids":["https://openalex.org/I2801704036","https://openalex.org/I4405271435","https://openalex.org/I87048295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082183026","display_name":"Emmanouil Tsamis","orcid":"https://orcid.org/0000-0001-7418-1033","observed_orcids":["https://orcid.org/0000-0001-7418-1033"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Emmanouil Tsamis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076807354","display_name":"Francesco Stringa","orcid":"https://orcid.org/0000-0002-1479-5727","observed_orcids":["https://orcid.org/0000-0002-1479-5727"]},"institutions":[{"id":"https://openalex.org/I2801704036","display_name":"Manchester Royal Eye Hospital","ror":"https://ror.org/04xtpk854","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801704036","https://openalex.org/I4210092852","https://openalex.org/I4210166818"]},{"id":"https://openalex.org/I4405271435","display_name":"NIHR Manchester Clinical Research Facility","ror":"https://ror.org/02e706q76","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4405271435"]},{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Francesco Stringa","raw_affiliation_strings":["Manchester Vision Regeneration (MVR) Lab at Manchester Royal Eye Hospital & NIHR/Wellcome Trust Manchester CRF, Manchester,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Vision Regeneration (MVR) Lab at Manchester Royal Eye Hospital & NIHR/Wellcome Trust Manchester CRF, Manchester,","institution_ids":["https://openalex.org/I2801704036","https://openalex.org/I4405271435","https://openalex.org/I87048295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071059737","display_name":"Tim Cole","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121807","display_name":"Topcon (United Kingdom)","ror":"https://ror.org/02qrpm067","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210121807","https://openalex.org/I4210139383"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tim Cole","raw_affiliation_strings":["Topcon (GB) Ltd., Newbury, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Topcon (GB) Ltd., Newbury, UK","institution_ids":["https://openalex.org/I4210121807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074667575","display_name":"Yvonne B. D\u2019souza","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yvonne D'Souza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5045793276","display_name":"Assad Jalil","orcid":"https://orcid.org/0000-0003-3820-137X","observed_orcids":["https://orcid.org/0000-0003-3820-137X"]},"institutions":[{"id":"https://openalex.org/I2801704036","display_name":"Manchester Royal Eye Hospital","ror":"https://ror.org/04xtpk854","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801704036","https://openalex.org/I4210092852","https://openalex.org/I4210166818"]},{"id":"https://openalex.org/I4405271435","display_name":"NIHR Manchester Clinical Research Facility","ror":"https://ror.org/02e706q76","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4405271435"]},{"id":"https://openalex.org/I87048295","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I87048295"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Assad Jalil","raw_affiliation_strings":["Manchester Vision Regeneration (MVR) Lab at Manchester Royal Eye Hospital & NIHR/Wellcome Trust Manchester CRF, Manchester,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Manchester Vision Regeneration (MVR) Lab at Manchester Royal Eye Hospital & NIHR/Wellcome Trust Manchester CRF, Manchester,","institution_ids":["https://openalex.org/I2801704036","https://openalex.org/I4405271435","https://openalex.org/I87048295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":47.4592,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.99839615,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"56","issue":null,"first_page":"113","last_page":"121"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.01679999940097332,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11569","display_name":"Optical Coherence Tomography Applications","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetic-retinopathy","display_name":"diabetic retinopathy","score":0.8870000243186951},{"id":"https://openalex.org/keywords/diabetic-maculopathy","display_name":"diabetic maculopathy","score":0.8199999928474426},{"id":"https://openalex.org/keywords/diabetic-macular-edema","display_name":"diabetic macular edema","score":0.847000002861023},{"id":"https://openalex.org/keywords/neovascularization","display_name":"neovascularization","score":0.7599999904632568},{"id":"https://openalex.org/keywords/foveal-avascular-zone","display_name":"foveal avascular zone","score":0.7720000147819519},{"id":"https://openalex.org/keywords/microvascular-lesions","display_name":"microvascular lesions","score":0.781000018119812},{"id":"https://openalex.org/keywords/swept-source-oct-angiography","display_name":"swept-source OCT angiography","score":0.7630000114440918},{"id":"https://openalex.org/keywords/fundus-fluorescein-angiography","display_name":"fundus fluorescein angiography","score":0.8629999756813049},{"id":"https://openalex.org/keywords/peripheral-retina","display_name":"peripheral retina","score":0.7099999785423279}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8979476690292358},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.7085713148117065},{"id":"https://openalex.org/C2779829184","wikidata":"https://www.wikidata.org/wiki/Q631361","display_name":"Diabetic retinopathy","level":3,"score":0.6369677186012268},{"id":"https://openalex.org/C2908587252","wikidata":"https://www.wikidata.org/wiki/Q1434206","display_name":"Fundus fluorescein angiography","level":4,"score":0.6106734275817871},{"id":"https://openalex.org/C2776391266","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Fundus (uterus)","level":2,"score":0.5703175663948059},{"id":"https://openalex.org/C2780643987","wikidata":"https://www.wikidata.org/wiki/Q468414","display_name":"Angiography","level":2,"score":0.5341737866401672},{"id":"https://openalex.org/C2781116099","wikidata":"https://www.wikidata.org/wiki/Q3842207","display_name":"Maculopathy","level":4,"score":0.5278964638710022},{"id":"https://openalex.org/C2780248432","wikidata":"https://www.wikidata.org/wiki/Q1434206","display_name":"Fluorescein angiography","level":3,"score":0.5122515559196472},{"id":"https://openalex.org/C2778818243","wikidata":"https://www.wikidata.org/wiki/Q899552","display_name":"Optical coherence tomography","level":2,"score":0.4539792239665985},{"id":"https://openalex.org/C2778313320","wikidata":"https://www.wikidata.org/wiki/Q550455","display_name":"Retinopathy","level":3,"score":0.34785985946655273},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.22720766067504883},{"id":"https://openalex.org/C2778257484","wikidata":"https://www.wikidata.org/wiki/Q555066","display_name":"Visual acuity","level":2,"score":0.2071644365787506},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.17626246809959412},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000792","descriptor_name":"Angiography","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D000792","descriptor_name":"Angiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008269","descriptor_name":"Macular Edema","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012171","descriptor_name":"Retinal Vessels","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D015861","descriptor_name":"Retinal Neovascularization","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D041623","descriptor_name":"Tomography, Optical Coherence","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1159/000442802","doi":"https://doi.org/10.1159/000442802","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000442802","pdf_url":null,"source":{"id":"https://openalex.org/S2755539230","display_name":"Developments in ophthalmology","issn_l":"0250-3751","issn":["0250-3751","1662-2790"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-100"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developments in Ophthalmology","raw_type":"book-chapter"},{"id":"pmid:27023703","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27023703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developments in ophthalmology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7300000190734863,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1471798439","https://openalex.org/W1504004192","https://openalex.org/W1989376395","https://openalex.org/W2010456451","https://openalex.org/W2016799658","https://openalex.org/W2048301902","https://openalex.org/W2085902754","https://openalex.org/W2091120447","https://openalex.org/W2125805162","https://openalex.org/W2152998339","https://openalex.org/W2159918287","https://openalex.org/W2596783883","https://openalex.org/W3134431802"],"related_works":["https://openalex.org/W2331994017","https://openalex.org/W4410062723","https://openalex.org/W2417923780","https://openalex.org/W4307378110","https://openalex.org/W2772865670","https://openalex.org/W4377290547","https://openalex.org/W3208740665","https://openalex.org/W4353104269","https://openalex.org/W2048301902","https://openalex.org/W3212647759"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"describe":[2],"the":[3,41,65,106,115,120,138,167,175,190,206,219,240,251,258,261],"optical":[4],"coherence":[5],"tomography":[6],"(OCT)":[7],"angiography":[8,51],"(OCTA)":[9],"features":[10],"of":[11,21,40,77,119,137,155,166,172,189,210,216,218,227,229,242,260],"diabetic":[12,94,132],"retinopathy.":[13],"METHODS:":[14],"Retrospective":[15],"serial":[16],"case":[17],"reports":[18],"were":[19,62,74,144,158],"examined":[20],"patients":[22,71,79],"who":[23],"underwent":[24,82],"routine":[25],"clinical":[26],"examination":[27,86],"and":[28,36,44,135,179,208,222,254],"OCTA":[29,101,148,180,193],"with":[30,53,64,247],"both":[31],"DRI":[32],"OCT":[33,39],"Atlantis":[34],"prototype":[35],"Triton":[37],"Swept-Source":[38],"posterior":[42,243],"pole":[43,244],"mid-periphery.":[45],"When":[46],"considered":[47],"necessary,":[48],"fluorescein":[49],"fundus":[50,112],"(FFA)":[52],"OPTOS":[54],"California":[55],"wide-field":[56],"imaging":[57,198],"was":[58,102,181],"performed.":[59],"The":[60],"findings":[61],"compared":[63,246],"current":[66],"literature.":[67],"RESULTS:":[68],"Forty-three":[69],"consecutive":[70],"(86":[72],"eyes)":[73,81],"evaluated.":[75],"Fourteen":[76],"these":[78,185],"(28":[80],"an":[83,195],"additional":[84,203],"FFA":[85,143,161],"due":[87],"to":[88,104,183],"advanced":[89],"retinopathy":[90],"signs,":[91],"such":[92],"as":[93],"macular":[95,133],"edema,":[96,134],"ischemia":[97],"or":[98],"neovascularization":[99],"(NV).":[100],"able":[103,182],"detect":[105,184],"microvascular":[107],"lesions":[108,212],"observed":[109,141],"on":[110,128,142,147,160],"color":[111],"images":[113],"in":[114,149,162,187,213,223],"whole":[116],"sample.":[117],"Thirty-six":[118],"86":[121],"eyes":[122,169],"showed":[123],"foveal":[124],"avascular":[125],"zone":[126],"enlargement":[127],"OCTA.":[129],"Microvascular":[130],"lesions,":[131],"NV":[136,156,173,217,230],"optic":[139,220],"disc":[140,221],"also":[145],"detected":[146,159],"all":[150,214],"cases":[151,215,228],"(28/28":[152],"eyes).":[153],"Features":[154],"elsewhere":[157],"16/28":[163],"eyes.":[164,191],"Ten":[165],"16":[168],"had":[170],"signs":[171,186],"within":[174],"100":[176],"central":[177],"degrees,":[178],"9":[188],"CONCLUSION:":[192],"is":[194,235,255],"effective":[196],"noninvasive":[197],"technique":[199,238],"that":[200,233],"can":[201],"provide":[202],"information":[204],"regarding":[205],"localization":[207],"morphology":[209],"vascular":[211],"more":[224],"than":[225],"half":[226],"elsewhere,":[231],"suggesting":[232],"it":[234],"a":[236],"noninferior":[237],"for":[239,257],"study":[241,259],"alterations":[245],"FFA,":[248],"which":[249],"remains":[250],"gold":[252],"standard":[253],"fundamental":[256],"retinal":[262],"periphery.":[263]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}