{"id":"https://openalex.org/W2398873115","doi":null,"title":"[Liver cirrhosis due to chronic use of nitrofurantoin].","display_name":"[Liver cirrhosis due to chronic use of nitrofurantoin].","publication_year":2004,"publication_date":"2004-01-31","ids":{"openalex":"https://openalex.org/W2398873115","mag":"2398873115","pmid":"https://pubmed.ncbi.nlm.nih.gov/14983581"},"language":"nl","primary_location":{"id":"pmid:14983581","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14983581","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nederlands tijdschrift voor geneeskunde","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pure.rug.nl/ws/files/1140567028/Levercirrose_door_chronisch_gebruik_van_nitrofurantoine.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056079980","display_name":"Franke Volbeda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146510","display_name":"Isala","ror":"https://ror.org/046a2wj10","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210146510"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"F Volbeda","raw_affiliation_strings":["Locatie Sophia, afd. Interne Geneeskunde, Isala Klinieken, Zwolle. frankevolbeda@hotmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Locatie Sophia, afd. Interne Geneeskunde, Isala Klinieken, Zwolle. frankevolbeda@hotmail.com","institution_ids":["https://openalex.org/I4210146510"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111523184","display_name":"A. Mieke Jonker","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A M Jonker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043891777","display_name":"Joshua A. Vecht","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Vecht","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103433064","display_name":"Paul H P Groeneveld","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P H Groeneveld","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7079,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.64903756,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"148","issue":"5","first_page":"235","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitrofurantoin","display_name":"nitrofurantoin","score":0.9760000109672546},{"id":"https://openalex.org/keywords/drug-induced-liver-injury","display_name":"drug-induced liver injury","score":0.8500000238418579},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/hepatotoxicity","display_name":"hepatotoxicity","score":0.7110000252723694},{"id":"https://openalex.org/keywords/jaundice","display_name":"jaundice","score":0.6359999775886536},{"id":"https://openalex.org/keywords/liver-failure","display_name":"liver failure","score":0.6740000247955322},{"id":"https://openalex.org/keywords/urinary-tract-infection-prevention","display_name":"urinary tract infection prevention","score":0.8379999995231628},{"id":"https://openalex.org/keywords/older-women","display_name":"older women","score":0.6940000057220459},{"id":"https://openalex.org/keywords/renal-dysfunction","display_name":"renal dysfunction","score":0.9340000152587891},{"id":"https://openalex.org/keywords/drug-withdrawal","display_name":"drug withdrawal","score":0.5879999995231628},{"id":"https://openalex.org/keywords/liver-biopsy","display_name":"liver biopsy","score":0.5849999785423279}],"concepts":[{"id":"https://openalex.org/C2777629877","wikidata":"https://www.wikidata.org/wiki/Q422669","display_name":"Nitrofurantoin","level":4,"score":0.9888399839401245},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9499370455741882},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.7540419101715088},{"id":"https://openalex.org/C2780496750","wikidata":"https://www.wikidata.org/wiki/Q193889","display_name":"Ascites","level":2,"score":0.7033911347389221},{"id":"https://openalex.org/C2778456037","wikidata":"https://www.wikidata.org/wiki/Q133244","display_name":"Jaundice","level":2,"score":0.5289521217346191},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.49923229217529297},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4944016933441162},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4609317183494568},{"id":"https://openalex.org/C3018561737","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver damage","level":2,"score":0.4200904965400696},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.2201324701309204},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C2778512257","wikidata":"https://www.wikidata.org/wiki/Q256602","display_name":"Ciprofloxacin","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000892","descriptor_name":"Anti-Infective Agents, Urinary","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000892","descriptor_name":"Anti-Infective Agents, Urinary","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D009582","descriptor_name":"Nitrofurantoin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D009582","descriptor_name":"Nitrofurantoin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014552","descriptor_name":"Urinary Tract Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D014552","descriptor_name":"Urinary Tract Infections","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":5,"locations":[{"id":"pmid:14983581","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14983581","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nederlands tijdschrift voor geneeskunde","raw_type":"Case Reports"},{"id":"pmh:oai:pure.rug.nl:openaire/28669c3a-38c5-458f-a53f-37344578fa02","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/28669c3a-38c5-458f-a53f-37344578fa02","pdf_url":"https://pure.rug.nl/ws/files/1140567028/Levercirrose_door_chronisch_gebruik_van_nitrofurantoine.pdf","source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Volbeda, F, Jonker, A M, Vecht, J & Groeneveld, P H 2004, 'Levercirrose door chronisch gebruik van nitrofurantoine', Nederlands Tijdschrift voor Geneeskunde, vol. 148, no. 5, pp. 235-238.","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:rug:oai:pure.rug.nl:publications/28669c3a-38c5-458f-a53f-37344578fa02","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/28669c3a-38c5-458f-a53f-37344578fa02","pdf_url":null,"source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nederlands Tijdschrift voor Geneeskunde, 148(5), 235 - 238. NLM (Medline)","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2398873115","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14983581","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:2508311516","doi":null,"is_oa":false,"landing_page_url":"https://research.rug.nl/en/publications/liver-cirrhosis-due-to-chronic-use-of-nitrofurantoin","pdf_url":null,"source":{"id":"https://openalex.org/S87982657","display_name":"Nederlandsch tijdschrift voor geneeskunde/Nederlands tijdschrift voor geneeskunde/NTvG-databank","issn_l":"0028-2162","issn":["0028-2162","1569-013X","1876-8784"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-4","vabb-shw"],"host_organization":"https://openalex.org/P4310319919","host_organization_name":"Bohn Stafleu van Loghum","host_organization_lineage":["https://openalex.org/P4310319919","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Bohn Stafleu van Loghum","Springer Science+Business Media"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Nederlandsch tijdschrift voor geneeskunde/Nederlands tijdschrift voor geneeskunde/NTvG-databank","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pure.rug.nl:openaire/28669c3a-38c5-458f-a53f-37344578fa02","doi":null,"is_oa":true,"landing_page_url":"https://research.rug.nl/en/publications/28669c3a-38c5-458f-a53f-37344578fa02","pdf_url":"https://pure.rug.nl/ws/files/1140567028/Levercirrose_door_chronisch_gebruik_van_nitrofurantoine.pdf","source":{"id":"https://openalex.org/S4306400420","display_name":"University of Groningen research database (University of Groningen / Centre for Information Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I169381384","host_organization_name":"University of Groningen","host_organization_lineage":["https://openalex.org/I169381384"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Volbeda, F, Jonker, A M, Vecht, J & Groeneveld, P H 2004, 'Levercirrose door chronisch gebruik van nitrofurantoine', Nederlands Tijdschrift voor Geneeskunde, vol. 148, no. 5, pp. 235-238.","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2398873115.pdf","grobid_xml":"https://content.openalex.org/works/W2398873115.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2508311516","https://openalex.org/W2131394773","https://openalex.org/W69182721","https://openalex.org/W7067475183","https://openalex.org/W2418952342","https://openalex.org/W2317260904","https://openalex.org/W4400895813","https://openalex.org/W6977529175","https://openalex.org/W2413071838","https://openalex.org/W2138128197"],"abstract_inverted_index":{"A":[0],"74-year-old":[1],"woman":[2],"was":[3,8,61,71],"admitted":[4],"with":[5,14,89,105,116],"jaundice.":[6],"She":[7],"suffering":[9],"from":[10],"generalised":[11],"liver":[12,54,87,123],"failure":[13],"a":[15,20,36,72,108,126],"highly":[16],"prolonged":[17],"prothrombin":[18],"time,":[19],"low":[21],"albumin":[22],"level":[23],"and":[24,76,114],"ascites.":[25],"Further":[26],"anamnesis":[27],"revealed":[28,85],"that":[29],"she":[30],"had":[31],"been":[32],"taking":[33],"nitrofurantoin":[34,69,131],"as":[35,92,107,125],"prophylactic":[37,109],"agent":[38,110],"for":[39,46,53],"recurrent":[40],"urinary":[41],"tract":[42],"infections":[43],"every":[44],"day":[45],"5":[47],"years.":[48],"Because":[49],"of":[50,68,99,122,130],"the":[51,59,83,120],"indications":[52],"damage":[55,88,124],"due":[56],"to":[57,81],"nitrofurantoin,":[58],"drug":[60],"discontinued":[62],"immediately":[63],"on":[64],"admission.":[65],"After":[66],"withdrawal":[67],"there":[70],"very":[73],"gradual":[74],"clinical":[75],"biochemical":[77],"improvement.":[78],"Liver":[79],"biopsies":[80],"confirm":[82],"diagnosis":[84],"extensive":[86],"cirrhosis":[90],"such":[91],"may":[93],"be":[94,103],"seen":[95],"following":[96],"long-term":[97],"use":[98],"nitrofurantoin.":[100],"Nitrofurantoin":[101],"should":[102],"prescribed":[104],"caution":[106],"in":[111,135],"elderly":[112],"women":[113],"patients":[115],"renal":[117],"dysfunction":[118],"because":[119],"risk":[121],"serious":[127],"side":[128],"effect":[129],"is":[132],"greatly":[133],"increased":[134],"these":[136],"patients.":[137]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}