{"id":"https://openalex.org/W2398840918","doi":null,"title":"Patterns of dyslipoproteinemia in selected North American populations. The Lipid Research Clinics Program Prevalence Study.","display_name":"Patterns of dyslipoproteinemia in selected North American populations. The Lipid Research Clinics Program Prevalence Study.","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W2398840918","mag":"2398840918","pmid":"https://pubmed.ncbi.nlm.nih.gov/3940679"},"language":"en","primary_location":{"id":"pmid:3940679","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3940679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111595807","display_name":"John C. LaRosa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J C LaRosa","raw_affiliation_strings":["(George Washington University)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(George Washington University)","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006049651","display_name":"Lloyd E. Chambless","orcid":"https://orcid.org/0000-0003-1695-5066","observed_orcids":["https://orcid.org/0000-0003-1695-5066"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L E Chambless","raw_affiliation_strings":["(George Washington University)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(George Washington University)","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002475361","display_name":"Michael H. Criqui","orcid":"https://orcid.org/0000-0003-0425-9661","observed_orcids":["https://orcid.org/0000-0003-0425-9661"]},"institutions":[{"id":"https://openalex.org/I193531525","display_name":"George Washington University","ror":"https://ror.org/00y4zzh67","country_code":"US","type":"education","lineage":["https://openalex.org/I193531525"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M H Criqui","raw_affiliation_strings":["(George Washington University)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(George Washington University)","institution_ids":["https://openalex.org/I193531525"]}]},{"author_position":"middle","author":{"id":null,"display_name":"I D Frantz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I D Frantz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079058910","display_name":"Charles J. Glueck","orcid":"https://orcid.org/0000-0002-7932-9866","observed_orcids":["https://orcid.org/0000-0002-7932-9866"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C J Glueck","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015180002","display_name":"Gerardo M HEISS","orcid":"https://orcid.org/0000-0002-5418-5288","observed_orcids":["https://orcid.org/0000-0002-5418-5288"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Heiss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"J A Morrison","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J A Morrison","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.1887,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.88166112,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"73","issue":"1 Pt 2","first_page":"I12","last_page":"29"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.03660000115633011,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dyslipoproteinemia","display_name":"dyslipoproteinemia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/fredrickson-classification","display_name":"Fredrickson classification","score":0.7990000247955322},{"id":"https://openalex.org/keywords/type-iii-hyperlipoproteinemia","display_name":"type III hyperlipoproteinemia","score":0.7390000224113464},{"id":"https://openalex.org/keywords/type-v-hyperlipoproteinemia","display_name":"type V hyperlipoproteinemia","score":0.765999972820282},{"id":"https://openalex.org/keywords/type-i-hyperlipoproteinemia","display_name":"type I hyperlipoproteinemia","score":0.8399999737739563},{"id":"https://openalex.org/keywords/type-iib-hyperlipoproteinemia","display_name":"type IIb hyperlipoproteinemia","score":0.9300000071525574},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.7879999876022339},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9959999918937683},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9419999718666077},{"id":"https://openalex.org/keywords/oral-contraceptives","display_name":"oral contraceptives","score":0.7590000033378601},{"id":"https://openalex.org/keywords/postmenopausal-estrogen-therapy","display_name":"postmenopausal estrogen therapy","score":0.8500000238418579},{"id":"https://openalex.org/keywords/gonadal-hormones","display_name":"gonadal hormones","score":0.6700000166893005},{"id":"https://openalex.org/keywords/serum-lipids","display_name":"serum lipids","score":0.5709999799728394},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6830000281333923},{"id":"https://openalex.org/keywords/north-american-populations","display_name":"North American populations","score":0.7509999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7308033108711243},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.6180697679519653},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.6100755929946899},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5966871976852417},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.5845386981964111},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.5517635941505432},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5233601331710815},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.4596978425979614},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44918665289878845},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.4470920264720917},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.442646861076355},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.431708425283432},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20650765299797058},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16751304268836975},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.1130506694316864},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.05773279070854187}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003276","descriptor_name":"Contraceptives, Oral","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004967","descriptor_name":"Estrogens","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006951","descriptor_name":"Hyperlipoproteinemias","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006951","descriptor_name":"Hyperlipoproteinemias","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D007009","descriptor_name":"Hypolipoproteinemias","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D007009","descriptor_name":"Hypolipoproteinemias","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009656","descriptor_name":"North America","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3940679","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3940679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"Journal Article"},{"id":"mag:2398840918","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3940679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2417881193","https://openalex.org/W7136481716","https://openalex.org/W2005489973","https://openalex.org/W2969504282","https://openalex.org/W2054857349","https://openalex.org/W2019449389","https://openalex.org/W1997671690","https://openalex.org/W2380501683","https://openalex.org/W1486084197","https://openalex.org/W2146540358"],"abstract_inverted_index":{"This":[0],"article":[1],"describes":[2],"the":[3,33,97,114,140,156,177,201],"assignment":[4],"of":[5,32,36,82,116,128,142,160,176,179,200,203],"dyslipoproteinemia":[6],"(DLP)":[7],"in":[8,89,113,125,130,139,170,187],"several":[9],"free-living":[10,171],"North":[11],"American":[12],"populations":[13,132],"and":[14,18,47,50,56,60,68,75,86,104,120,133,162,196,207],"presents":[15],"mean":[16,102],"lipid":[17,206],"lipoprotein":[19,55,58,87,165,208],"levels":[20,88,106],"for":[21,42,53],"each":[22],"type.":[23],"Dyslipoproteinemic":[24],"phenotypes":[25,44,91,186],"were":[26,77,92,107],"assigned":[27],"by":[28],"a":[29],"modified":[30],"version":[31],"National":[34],"Institutes":[35],"Health":[37],"(Fredrickson)":[38],"phenotyping":[39],"system.":[40],"Criteria":[41],"assigning":[43],"included":[45],"age-":[46],"sex-specific":[48],"5th":[49],"95th":[51],"percentiles":[52],"low-density":[54],"high-density":[57],"cholesterol":[59,103],"total":[61],"triglyceride,":[62],"as":[63,65,94],"well":[64],"other":[66],"qualitative":[67],"quantitative":[69],"criteria.":[70],"Phenotypes":[71],"IIb,":[72],"III,":[73],"I,":[74],"V":[76],"uncommon,":[78],"confirming":[79],"clinical":[80,174],"impressions":[81,175],"their":[83],"frequency.":[84],"Lipid":[85],"specific":[90],"generally":[93],"expected.":[95],"In":[96,151],"type":[98],"III":[99],"phenotype,":[100],"however,":[101],"triglyceride":[105],"surprisingly":[108],"low.":[109],"Gonadal":[110],"hormone":[111],"use,":[112],"form":[115],"both":[117],"oral":[118],"contraceptives":[119],"postmenopausal":[121],"estrogens,":[122],"was":[123,134],"reported":[124],"approximately":[126],"30%":[127],"women":[129,147],"these":[131,153],"associated":[135],"with":[136,146],"dramatic":[137],"differences":[138,154],"frequency":[141],"DLP":[143],"when":[144],"compared":[145],"not":[148],"taking":[149],"hormones.":[150],"general,":[152],"reflected":[155],"previously":[157],"described":[158],"effects":[159],"estrogen":[161],"progestins":[163],"on":[164,184,205],"levels.":[166,209],"These":[167],"data":[168],"gathered":[169],"populations:":[172],"confirm":[173],"rarity":[178],"some":[180],"phenotypes,":[181],"focus":[182],"attention":[183],"those":[185],"which":[188],"diminished":[189],"rather":[190],"than":[191],"elevated":[192],"lipoproteins":[193],"are":[194],"found,":[195],"provide":[197],"further":[198],"evidence":[199],"effect":[202],"hormones":[204]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}