{"id":"https://openalex.org/W2398801946","doi":null,"title":"Peroxidase-mediated formation of the fungal polyphenol 3,14'-bihispidinyl.","display_name":"Peroxidase-mediated formation of the fungal polyphenol 3,14'-bihispidinyl.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2398801946","mag":"2398801946","pmid":"https://pubmed.ncbi.nlm.nih.gov/18239425"},"language":"en","primary_location":{"id":"pmid:18239425","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18239425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology and biotechnology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111633475","display_name":"In-Kyoung Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"In-Kyoung Lee","raw_affiliation_strings":["Functional Metabolomics Research Center, KRIBB, Daejeon 305-333, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Functional Metabolomics Research Center, KRIBB, Daejeon 305-333, Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111484507","display_name":"Bong-Sik Yun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bong-Sik Yun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7809,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.64569191,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"18","issue":"1","first_page":"107","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.4514000117778778,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.4514000117778778,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12673","display_name":"Microbial Metabolism and Applications","score":0.23510000109672546,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11136","display_name":"Enzyme-mediated dye degradation","score":0.06650000065565109,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hispidin","display_name":"hispidin","score":0.7850000262260437},{"id":"https://openalex.org/keywords/horseradish-peroxidase","display_name":"horseradish peroxidase","score":0.9169999957084656},{"id":"https://openalex.org/keywords/oxidative-coupling","display_name":"oxidative coupling","score":0.890999972820282},{"id":"https://openalex.org/keywords/fungal-pigments","display_name":"fungal pigments","score":0.7250000238418579},{"id":"https://openalex.org/keywords/phellinus-linteus","display_name":"Phellinus linteus","score":0.9710000157356262},{"id":"https://openalex.org/keywords/enzymatic-synthesis","display_name":"enzymatic synthesis","score":0.5640000104904175},{"id":"https://openalex.org/keywords/ligninolytic-enzymes","display_name":"ligninolytic enzymes","score":0.7760000228881836}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7356745004653931},{"id":"https://openalex.org/C2778326925","wikidata":"https://www.wikidata.org/wiki/Q5353642","display_name":"Phellinus linteus","level":3,"score":0.5871554613113403},{"id":"https://openalex.org/C2779546866","wikidata":"https://www.wikidata.org/wiki/Q531306","display_name":"Dimer","level":2,"score":0.5828157067298889},{"id":"https://openalex.org/C162008176","wikidata":"https://www.wikidata.org/wiki/Q419305","display_name":"Peroxidase","level":3,"score":0.5753352046012878},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4788762927055359},{"id":"https://openalex.org/C2777676563","wikidata":"https://www.wikidata.org/wiki/Q413665","display_name":"Horseradish peroxidase","level":3,"score":0.4598454236984253},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.39445266127586365},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.34554556012153625},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2312374711036682},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13589119911193848},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.08427268266677856},{"id":"https://openalex.org/C133479454","wikidata":"https://www.wikidata.org/wiki/Q326228","display_name":"Mycelium","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000363","descriptor_name":"Agaricales","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D000363","descriptor_name":"Agaricales","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D000363","descriptor_name":"Agaricales","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005285","descriptor_name":"Fermentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D005419","descriptor_name":"Flavonoids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006735","descriptor_name":"Horseradish Peroxidase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010636","descriptor_name":"Phenols","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011753","descriptor_name":"Pyrones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011753","descriptor_name":"Pyrones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019281","descriptor_name":"Dimerization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmid:18239425","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18239425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microbiology and biotechnology","raw_type":"Journal Article"},{"id":"pmh:oai:http://repository.kribb.re.kr:8080/:201005/8283","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/201005/8283","pdf_url":null,"source":{"id":"https://openalex.org/S4406922719","display_name":"KRIBB Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"/dspace/upload/original/7432.pdf","raw_type":"Article"},{"id":"pmh:oai:https://repository.kribb.re.kr:201005/8283","doi":null,"is_oa":false,"landing_page_url":"https://repository.kribb.re.kr/handle/201005/8283","pdf_url":null,"source":{"id":"https://openalex.org/S4406922719","display_name":"KRIBB Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"/dspace/upload/original/7432.pdf","raw_type":"Article"},{"id":"mag:2398801946","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18239425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2069705936","https://openalex.org/W2301859992","https://openalex.org/W4400311865","https://openalex.org/W2951563296","https://openalex.org/W4400321542","https://openalex.org/W2044853727","https://openalex.org/W4315486832","https://openalex.org/W2069693755","https://openalex.org/W7154946958","https://openalex.org/W4229453502"],"abstract_inverted_index":{"Medicinal":[0],"fungi,":[1],"Phellinus":[2],"linteus":[3],"and":[4,39,45,68,113,128,142],"Inonotus":[5],"xeranticus,":[6],"produce":[7],"a":[8,34,101],"cluster":[9],"of":[10,23,30,59,72,87,131,138],"yellow":[11],"pigment":[12,27],"in":[13,135,158],"their":[14],"fermentation":[15],"broth":[16],"that":[17,121,144],"acts":[18],"as":[19],"an":[20],"important":[21],"element":[22],"biological":[24],"activity.":[25],"The":[26],"is":[28],"composed":[29],"diverse":[31],"polyphenols":[32],"with":[33],"styrylpyrone":[35],"moiety,":[36],"mainly":[37],"hispidin":[38,89,92,102,155],"its":[40],"dimers,":[41,110],"3,14'-bihispidinyl,":[42,104],"hypholomine":[43,111],"B,":[44],"1,1-":[46],"distrylpyrylethan.":[47],"Although":[48],"dimeric":[49],"hispidins":[50,132],"were":[51,115],"proposed":[52],"to":[53,83,152],"be":[54,150],"biosynthesized":[55],"from":[56,91],"two":[57],"molecules":[58],"monomer":[60],"via":[61],"oxidative":[62,123],"coupling":[63,124],"by":[64,93,140],"ligninolytic":[65],"enzymes,":[66],"laccase":[67],"peroxidase,":[69],"the":[70,88,108,122,126,136,159],"details":[71],"this":[73,78],"process":[74,137],"remain":[75],"unknown.":[76],"In":[77],"preliminary":[79],"study,":[80],"we":[81],"attempted":[82],"achieve":[84],"enzymatic":[85],"synthesis":[86],"dimer":[90],"using":[94],"commercially":[95],"available":[96],"horseradish":[97],"peroxidase":[98],"(HRP).":[99],"Consequently,":[100],"dimer,":[103],"was":[105,133],"synthesized,":[106],"whereas":[107],"other":[109,154],"B":[112],"1,1-distrylpyrylethan,":[114],"not":[116],"produced.":[117],"This":[118],"result":[119],"suggested":[120],"at":[125],"C-3":[127],"C-14'":[129],"positions":[130],"dominant":[134],"dimerization":[139],"HRP,":[141],"indicated":[143],"additional":[145],"catalysts":[146],"or":[147],"substrates":[148],"would":[149],"needed":[151],"synthesize":[153],"dimers":[156],"present":[157],"fungal":[160],"metabolite.":[161]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}