{"id":"https://openalex.org/W2398565641","doi":"https://doi.org/10.2169/naika.69.1299","title":"CLINICAL SIGNIFICANCE OF DETERMINING PLASMA PYRUVATE KINASE (PK) ACTIVITY IN ACUTE MYOCARDIAL INFARCTION","display_name":"CLINICAL SIGNIFICANCE OF DETERMINING PLASMA PYRUVATE KINASE (PK) ACTIVITY IN ACUTE MYOCARDIAL INFARCTION","publication_year":1980,"publication_date":"1980-01-01","ids":{"openalex":"https://openalex.org/W2398565641","doi":"https://doi.org/10.2169/naika.69.1299","mag":"2398565641","pmid":"https://pubmed.ncbi.nlm.nih.gov/7462763"},"language":"ja","primary_location":{"id":"doi:10.2169/naika.69.1299","doi":"https://doi.org/10.2169/naika.69.1299","is_oa":true,"landing_page_url":"https://doi.org/10.2169/naika.69.1299","pdf_url":"https://www.jstage.jst.go.jp/article/naika1913/69/10/69_10_1299/_pdf","source":{"id":"https://openalex.org/S4210221755","display_name":"Nihon Naika Gakkai Zasshi","issn_l":"0021-5384","issn":["0021-5384","1883-2083"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai Zasshi","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/naika1913/69/10/69_10_1299/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113436382","display_name":"Sugao Fukui","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Sugao FUKUI","raw_affiliation_strings":["Cardiovascular Division, Sakurabashi Watanabe Hospital","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","The Third Department of Medicine, Shiga University of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hoga KIM","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hoga KIM","raw_affiliation_strings":["Cardiovascular Division, Sakurabashi Watanabe Hospital","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","The Third Department of Medicine, Shiga University of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062836884","display_name":"Nobuhisa OHGIDANI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuhisa OHGIDANI","raw_affiliation_strings":["Cardiovascular Division, Sakurabashi Watanabe Hospital","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","The Third Department of Medicine, Shiga University of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109801443","display_name":"Takazo Minamino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takazo MINAMINO","raw_affiliation_strings":["Cardiovascular Division, Sakurabashi Watanabe Hospital","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","The Third Department of Medicine, Shiga University of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113806012","display_name":"Yutaka Harano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yutaka HARANO","raw_affiliation_strings":["The Third Department of Medicine, Shiga University of Medical Science","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103530711","display_name":"Yukio Shigeta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukio SHIGETA","raw_affiliation_strings":["The Third Department of Medicine, Shiga University of Medical Science","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111735548","display_name":"Masatsugu Hori","orcid":"https://orcid.org/0009-0002-6974-0085","observed_orcids":["https://orcid.org/0009-0002-6974-0085"]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masatsugu HORI","raw_affiliation_strings":["The First Department of Medicine, Medical School, Osaka University","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","The Third Department of Medicine, Shiga University of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Department of Medicine, Medical School, Osaka University","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110824493","display_name":"Michitoshi Inoue","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Michitoshi INOUE","raw_affiliation_strings":["The First Department of Medicine, Medical School, Osaka University","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","The Third Department of Medicine, Shiga University of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Department of Medicine, Medical School, Osaka University","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008951046","display_name":"Hiroshi Abe","orcid":"https://orcid.org/0000-0001-9659-8382","observed_orcids":["https://orcid.org/0000-0001-9659-8382"]},"institutions":[{"id":"https://openalex.org/I160046202","display_name":"Shiga University of Medical Science","ror":"https://ror.org/00d8gp927","country_code":"JP","type":"education","lineage":["https://openalex.org/I160046202"]},{"id":"https://openalex.org/I4210138602","display_name":"Sakurabashi Watanabe Hospital","ror":"https://ror.org/03rx00z90","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210138602"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroshi ABE","raw_affiliation_strings":["The First Department of Medicine, Medical School, Osaka University","Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","The Third Department of Medicine, Shiga University of Medical Science"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Department of Medicine, Medical School, Osaka University","institution_ids":["https://openalex.org/I98285908"]},{"raw_affiliation_string":"Cardiovascular Division, Sakurabashi Watanabe Hospital, Osaka","institution_ids":["https://openalex.org/I4210138602"]},{"raw_affiliation_string":"The Third Department of Medicine, Shiga University of Medical Science","institution_ids":["https://openalex.org/I160046202"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.25445487,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"69","issue":"10","first_page":"1299","last_page":"1304"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.9990000128746033},{"id":"https://openalex.org/keywords/creatine-kinase","display_name":"creatine kinase","score":0.9509999752044678},{"id":"https://openalex.org/keywords/cardiac-enzymes","display_name":"cardiac enzymes","score":0.45899999141693115},{"id":"https://openalex.org/keywords/enzyme-kinetics","display_name":"enzyme kinetics","score":0.5950000286102295},{"id":"https://openalex.org/keywords/enzyme-clearance","display_name":"enzyme clearance","score":0.46000000834465027},{"id":"https://openalex.org/keywords/myocardial-infarction-diagnosis","display_name":"myocardial infarction diagnosis","score":0.640999972820282},{"id":"https://openalex.org/keywords/recurrent-myocardial-infarction","display_name":"reinfarction","score":0.8029999732971191},{"id":"https://openalex.org/keywords/congestive-heart-failure","display_name":"congestive heart failure","score":0.7639999985694885},{"id":"https://openalex.org/keywords/coronary-angiography","display_name":"coronary angiography","score":0.8029999732971191},{"id":"https://openalex.org/keywords/lactate-dehydrogenase","display_name":"lactate dehydrogenase","score":0.7839999794960022},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.8479999899864197},{"id":"https://openalex.org/keywords/alpha-hydroxybutyryl-dehydrogenase","display_name":"alpha-hydroxybutyryl dehydrogenase","score":0.9589999914169312}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8614569902420044},{"id":"https://openalex.org/C36880943","wikidata":"https://www.wikidata.org/wiki/Q409458","display_name":"Creatine kinase","level":2,"score":0.733862042427063},{"id":"https://openalex.org/C2777318727","wikidata":"https://www.wikidata.org/wiki/Q409464","display_name":"Lactate dehydrogenase","level":3,"score":0.6681803464889526},{"id":"https://openalex.org/C2780854706","wikidata":"https://www.wikidata.org/wiki/Q900970","display_name":"Pyruvate kinase","level":4,"score":0.5833072066307068},{"id":"https://openalex.org/C2993497327","wikidata":"https://www.wikidata.org/wiki/Q409464","display_name":"Lactic dehydrogenase","level":3,"score":0.580811619758606},{"id":"https://openalex.org/C2776877979","wikidata":"https://www.wikidata.org/wiki/Q424288","display_name":"Transaminase","level":3,"score":0.43601691722869873},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.4129534065723419},{"id":"https://openalex.org/C9506865","wikidata":"https://www.wikidata.org/wiki/Q6321025","display_name":"Pyruvate dehydrogenase kinase","level":4,"score":0.4118482768535614},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4068111181259155},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3453124463558197},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3317308723926544},{"id":"https://openalex.org/C88099638","wikidata":"https://www.wikidata.org/wiki/Q412856","display_name":"Pyruvate dehydrogenase complex","level":3,"score":0.3137262463569641},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3129445016384125},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28987324237823486},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.1491680145263672},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.11908990144729614},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06234472990036011}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001219","descriptor_name":"Aspartate Aminotransferases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003402","descriptor_name":"Creatine Kinase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006884","descriptor_name":"Hydroxybutyrate Dehydrogenase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007770","descriptor_name":"L-Lactate Dehydrogenase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D011770","descriptor_name":"Pyruvate Kinase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2169/naika.69.1299","doi":"https://doi.org/10.2169/naika.69.1299","is_oa":true,"landing_page_url":"https://doi.org/10.2169/naika.69.1299","pdf_url":"https://www.jstage.jst.go.jp/article/naika1913/69/10/69_10_1299/_pdf","source":{"id":"https://openalex.org/S4210221755","display_name":"Nihon Naika Gakkai Zasshi","issn_l":"0021-5384","issn":["0021-5384","1883-2083"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai Zasshi","raw_type":"journal-article"},{"id":"pmid:7462763","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7462763","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2169/naika.69.1299","doi":"https://doi.org/10.2169/naika.69.1299","is_oa":true,"landing_page_url":"https://doi.org/10.2169/naika.69.1299","pdf_url":"https://www.jstage.jst.go.jp/article/naika1913/69/10/69_10_1299/_pdf","source":{"id":"https://openalex.org/S4210221755","display_name":"Nihon Naika Gakkai Zasshi","issn_l":"0021-5384","issn":["0021-5384","1883-2083"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20"],"host_organization":"https://openalex.org/P4310313351","host_organization_name":"The Japanese Society of Internal Medicine","host_organization_lineage":["https://openalex.org/P4310313351"],"host_organization_lineage_names":["The Japanese Society of Internal Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Naika Gakkai Zasshi","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2398565641.pdf","grobid_xml":"https://content.openalex.org/works/W2398565641.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W649740210","https://openalex.org/W401353052","https://openalex.org/W2142980936","https://openalex.org/W349310832","https://openalex.org/W968324668","https://openalex.org/W2726718648","https://openalex.org/W2404593616","https://openalex.org/W3033680227","https://openalex.org/W600315426","https://openalex.org/W2408029885"],"abstract_inverted_index":{"\u6025\u6027\u5fc3\u7b4b\u786c\u585e\u75c7\u4f8b\u306b\u304a\u3051\u308b\u8840\u4e2dpyruvate":[0],"kinase(PK)\u6e2c\u5b9a\u306e\u81e8\u5e8a\u7684\u610f\u7fa9\u3092\u691c\u8a0e\u3059\u308b\u305f\u3081\u306b,\u6025\u6027\u5fc3\u7b4b\u786c\u585e\u75c741\u4f8b\u3092\u5bfe\u8c61\u306b\u5165\u9662\u76f4\u5f8c\u3088\u308a\u7d4c\u6642\u7684\u306b\u8840\u6f3fPK,\u8840\u6e05creatine":[1],"phosphokinase":[2],"(CPK),":[3],"glutamic":[4],"oxaloacetic":[5],"transaminase":[6],"(GOT),":[7],"lactic":[8],"dehydrogenase":[9,11],"(LDH)\u304a\u3088\u3073\u03b1-hydroxybutyrlc":[10],"(HBD)\u3092\u6e2c\u5b9a\u3057,\u305d\u308c\u305e\u308c\u306e\u9175\u7d20\u5024\u304c\u6700\u5927\u306b\u306a\u308b\u307e\u3067\u306e\u6642\u9593,\u786c\u585e\u767a\u75c7\u304b\u3089\u8840\u6e05\u9175\u7d20\u5024\u304c\u6b63\u5e38\u306b\u5fa9\u3059\u308b\u307e\u3067\u306e\u6642\u9593\u304a\u3088\u3073\u9175\u7d20\u306e\u8840\u4e2d\u304b\u3089\u306e\u6d88\u5931\u7387\u3092\u6c42\u3081\u305f.\u3055\u3089\u306b\u5404\u9175\u7d20\u306e\u8a3a\u65ad\u4e0a\u306e\u7279\u5fae\u3092\u628a\u63e1\u3059\u308b\u305f\u3081\u306b,\u5fc3\u7b4b\u786c\u585e\u4ee5\u5916\u306e\u5fc3\u75be\u60a3\u304a\u3088\u3073\u51a0\u52d5\u8108\u9020\u5f71(CAG)\u65bd\u884c\u5f8c\u306e\u9175\u7d20\u306e\u4e0a\u6607\u306e\u6709\u7121\u3092\u691c\u8a0e\u3057\u305f.\u305d\u306e\u7d50\u679c,":[12],"(1)\u8840\u6f3fPK\u306f\u5bfe\u8c61\u5168\u4f8b\u306b\u6709\u610f\u306e\u4e0a\u6607\u3092\u8a8d\u3081,\u786c\u585e\u767a\u75c7\u304b\u3089\u6700\u9ad8\u5024\u306b\u9054\u3059\u308b\u6642\u9593\u306f\u5e73\u574723.7\u00b110.9(SD)\u6642\u9593\u3067CPK\u306b\u3064\u3044\u3067\u65e9\u304f,\u6b63\u5e38\u5024\u306b\u5fa9\u3059\u308b\u307e\u3067\u306e\u6642\u9593\u306f\u5e73\u574759.0\u00b122.4(SD)\u6642\u9593\u3068\u6e2c\u5b9a\u9175\u7d20\u4e2d\u6700\u3082\u65e9\u304b\u3064\u305f.\u307e\u305fPK\u306e\u8840\u4e2d\u304b\u3089\u306e\u6d88\u5931\u7387\u306f\u5e73\u57470.0486\u00b10.0218(SD)/\u6642\u9593\u3067\u3042\u3064\u305f,\u3053\u306e\u3053\u3068\u3088\u308a\u5fc3\u7b4b\u786c\u585e\u75c7\u4f8b\u306b\u304a\u3051\u308b\u8840\u6f3fPK\u306e\u6e2c\u5b9a\u306f\u786c\u585e\u306e\u62e1\u5927\u304a\u3088\u3073\u518d\u786c\u585e\u306e\u65e9\u671f\u8a3a\u65ad\u306b\u6709\u7528\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u305f.":[13],"(2)\u8840\u6f3fPK\u306f\u3046\u3064\u8840\u6027\u5fc3\u4e0d\u5168\u3067\u306f\u4e0a\u6607\u3057\u306a\u304b\u3064\u305f.":[14],"(3)\u51a0\u52d5\u8108\u9020\u5f71\u3092\u65bd\u884c\u3057\u305f20\u4f8b\u4e2d10\u4f8b\u306b\u8840\u6e05CPK\u306e\u4e0a\u6607\u3092\u8a8d\u3081\u305f\u306e\u306b\u5bfe\u3057,\u8840\u6f3fPK\u306f4\u4f8b\u306e\u307f\u306b\u8efd\u5ea6\u306e\u4e0a\u6607\u3092\u8a8d\u3081\u305f\u306b\u904e\u304e\u305a,":[15],"PK\u306fCPK\u3088\u308a\u5fc3\u7b4b\u7d30\u80de\u3088\u308a\u904a\u51fa\u3057\u96e3\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u305f.":[16]},"counts_by_year":[],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}