{"id":"https://openalex.org/W2398488462","doi":null,"title":"Effect of personalized dietary intervention on nutritional, metabolic and vascular indices in patients with chronic kidney disease.","display_name":"Effect of personalized dietary intervention on nutritional, metabolic and vascular indices in patients with chronic kidney disease.","publication_year":2015,"publication_date":"2015-09-01","ids":{"openalex":"https://openalex.org/W2398488462","mag":"2398488462","pmid":"https://pubmed.ncbi.nlm.nih.gov/26439028"},"language":"en","primary_location":{"id":"pmid:26439028","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26439028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European review for medical and pharmacological sciences","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"S Lai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S Lai","raw_affiliation_strings":["Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy. silvia.lai@uniroma1.it","Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Medicine, Sapienza University of Rome, Rome, Italy. silvia.lai@uniroma1.it","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":"Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016239156","display_name":"Alessio Molfino","orcid":"https://orcid.org/0000-0002-6432-0236","observed_orcids":["https://orcid.org/0000-0002-6432-0236"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Molfino","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001004630","display_name":"Bettina Coppola","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"B Coppola","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S De Leo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S De Leo","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":null,"display_name":"V Tommasi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"V Tommasi","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001755966","display_name":"Alessandro Galani","orcid":"https://orcid.org/0000-0001-5683-6841","observed_orcids":["https://orcid.org/0000-0001-5683-6841"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Galani","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006150148","display_name":"Silvia Migliaccio","orcid":"https://orcid.org/0000-0002-4563-6630","observed_orcids":["https://orcid.org/0000-0002-4563-6630"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S Migliaccio","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045188156","display_name":"Emanuela Alessandra Greco","orcid":"https://orcid.org/0000-0003-0603-4079","observed_orcids":["https://orcid.org/0000-0003-0603-4079"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"E A Greco","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069471071","display_name":"Tania Gnerre Musto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"T Gnerre Musto","raw_affiliation_strings":["University of Rome, La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome, La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"last","author":{"id":null,"display_name":"M Muscaritoli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Muscaritoli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.099,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.91278915,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"19","issue":"18","first_page":"3351","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.953000009059906},{"id":"https://openalex.org/keywords/personalized-dietary-intervention","display_name":"personalized dietary intervention","score":0.8450000286102295},{"id":"https://openalex.org/keywords/low-protein-diet","display_name":"low-protein diet","score":1.0},{"id":"https://openalex.org/keywords/malnutrition","display_name":"malnutrition","score":0.734000027179718},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.7710000276565552},{"id":"https://openalex.org/keywords/carotid-intima-media-thickness","display_name":"carotid intima-media thickness","score":0.9539999961853027},{"id":"https://openalex.org/keywords/flow-mediated-dilation","display_name":"flow-mediated dilation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.574999988079071},{"id":"https://openalex.org/keywords/phosphorus","display_name":"phosphorus","score":0.8090000152587891},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9660000205039978},{"id":"https://openalex.org/keywords/acid-base-balance","display_name":"acid-base balance","score":0.8679999709129333},{"id":"https://openalex.org/keywords/bone-mineral-density","display_name":"bone mineral density","score":0.7480000257492065},{"id":"https://openalex.org/keywords/muscle-mass","display_name":"muscle mass","score":0.8489999771118164},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.6420000195503235},{"id":"https://openalex.org/keywords/pre-dialysis-patients","display_name":"predialysis","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8103104829788208},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.7257080674171448},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6605432629585266},{"id":"https://openalex.org/C33872192","wikidata":"https://www.wikidata.org/wiki/Q864287","display_name":"Bioelectrical impedance analysis","level":3,"score":0.6329021453857422},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.5314390063285828},{"id":"https://openalex.org/C14522933","wikidata":"https://www.wikidata.org/wiki/Q531507","display_name":"Micronutrient","level":2,"score":0.5159617066383362},{"id":"https://openalex.org/C551997983","wikidata":"https://www.wikidata.org/wiki/Q12167","display_name":"Malnutrition","level":2,"score":0.49452587962150574},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.46907418966293335},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.39558306336402893},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.34616929292678833},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.12989795207977295}],"mesh":[{"descriptor_ui":"D000138","descriptor_name":"Acidosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001823","descriptor_name":"Body Composition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009752","descriptor_name":"Nutritional Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014652","descriptor_name":"Vascular Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:26439028","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26439028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European review for medical and pharmacological sciences","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniroma1.it:11573/847775","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/847775","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2398488462","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26439028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2619474610","https://openalex.org/W2811084039","https://openalex.org/W3202069687","https://openalex.org/W4367321977","https://openalex.org/W2410300258","https://openalex.org/W2986048340","https://openalex.org/W3111426844","https://openalex.org/W1973969197","https://openalex.org/W4392162739","https://openalex.org/W7167484647"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Patients":[1],"with":[2,36,103],"chronic":[3],"kidney":[4],"disease":[5,22],"(CKD)":[6],"present":[7],"a":[8,24,38,65,166,183,205,229],"markedly":[9],"increased":[10],"cardiovascular":[11,253],"(CV)":[12],"morbidity":[13],"and":[14,23,30,80,97,117,131,141,150,175,182,193,214,228,251],"mortality":[15],"since":[16,42],"the":[17,21,43,62,72,151,210],"early":[18,44],"stages":[19,45,74],"of":[20,27,37,46,64,100,109,187,212,217,232],"high":[25],"prevalence":[26],"malnutrition,":[28],"inflammation,":[29],"accelerated":[31],"atherosclerosis.":[32],"Personalized":[33],"nutritional":[34,110],"intervention,":[35],"low-protein":[39,221],"diet":[40,222],"(LPD),":[41],"CKD":[47,73,104,213,241],"should":[48,235],"be":[49,236],"able":[50],"to":[51,238,245],"achieve":[52],"significant":[53,167,185],"metabolic":[54,79,247],"improvements.":[55],"In":[56],"our":[57],"study":[58],"we":[59,164],"have":[60,87],"verified":[61],"effects":[63],"personalized":[66],"dietary":[67,162],"intervention":[68,202],"in":[69,71,169,208,243],"patients":[70,102,242],"3/4":[75,106,240],"KDOQI":[76],"on":[77],"nutritional,":[78],"vascular":[81],"indices.":[82],"PATIENTS":[83],"AND":[84],"METHODS:":[85],"We":[86],"evaluated":[88],"renal":[89,249],"function,":[90],"lipid":[91],"profile,":[92,248],"mineral":[93,115],"metabolism,":[94],"inflammatory":[95],"indices,":[96],"acid-base":[98],"balance":[99],"16":[101],"(stages":[105],"KDOQI).":[107],"Assessment":[108],"status,":[111],"body":[112,121],"composition,":[113],"bone":[114],"density":[116],"muscle":[118],"mass,":[119],"using":[120],"mass":[122],"index":[123],"(BMI),":[124],"handgrip":[125],"strength,":[126],"bioelectrical":[127],"impedance":[128],"analysis":[129],"(BIA),":[130],"dual":[132],"energy":[133],"X-ray":[134],"absorptiometry":[135],"(DEXA)":[136],"was":[137],"performed.":[138],"Vascular":[139],"indices":[140],"endothelial":[142],"dysfunction":[143],"such":[144],"as":[145],"carotid":[146],"intima-media":[147],"thickness":[148],"(cIMT)":[149],"brachial":[152],"artery":[153],"flow-mediated":[154],"dilation":[155],"(baFMD)":[156],"were":[157],"also":[158],"analyzed.":[159],"RESULTS:":[160],"After":[161],"interventions,":[163],"observed":[165],"increase":[168],"plasma":[170],"bicarbonate":[171],"(p":[172,179,190,197],"=":[173,180,191,198],"0.004)":[174],"vitamin":[176],"D":[177],"levels":[178],"0.03)":[181],"concomitant":[184],"reduction":[186],"phosphorus":[188],"concentration":[189],"0.001)":[192],"C-reactive":[194],"protein":[195,226],"(CRP)":[196],"0.01).":[199],"CONCLUSIONS:":[200],"Nutritional":[201],"potentially":[203],"plays":[204],"major":[206],"role":[207],"reducing":[209],"progression":[211],"systemic":[215],"complications":[216],"predialysis":[218],"patients.":[219],"A":[220],"(LPD)":[223],"ensuring":[224],"vegetable":[225],"intake":[227],"reduced":[230],"amount":[231],"specific":[233],"micronutrients":[234],"recommended":[237],"stage":[239],"order":[244],"ameliorate":[246],"outcome,":[250],"reduce":[252],"risk":[254],"factors.":[255]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}