{"id":"https://openalex.org/W2398418149","doi":"https://doi.org/10.1200/jco.2009.27.15_suppl.9033","title":"Effect of ipilimumab treatment on 18-month survival: Update of patients (pts) with advanced melanoma treated with 10 mg/kg ipilimumab in three phase II clinical trials","display_name":"Effect of ipilimumab treatment on 18-month survival: Update of patients (pts) with advanced melanoma treated with 10 mg/kg ipilimumab in three phase II clinical trials","publication_year":2009,"publication_date":"2009-05-20","ids":{"openalex":"https://openalex.org/W2398418149","doi":"https://doi.org/10.1200/jco.2009.27.15_suppl.9033","mag":"2398418149"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2009.27.15_suppl.9033","doi":"https://doi.org/10.1200/jco.2009.27.15_suppl.9033","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2009.27.15_suppl.9033","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060495866","display_name":"Steven J O'Day","orcid":"https://orcid.org/0009-0005-5345-5417","observed_orcids":["https://orcid.org/0009-0005-5345-5417"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"S. O'Day","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047177507","display_name":"Jeffrey S. Weber","orcid":"https://orcid.org/0000-0002-4962-2957","observed_orcids":["https://orcid.org/0000-0002-4962-2957"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"J. Weber","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025478490","display_name":"C\u00e9l\u00e8ste Lebb\u00e9","orcid":"https://orcid.org/0000-0002-5854-7290","observed_orcids":["https://orcid.org/0000-0002-5854-7290"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"C. Lebbe","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M. Maio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"M. Maio","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112026684","display_name":"Hubert Pehamberger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"H. Pehamberger","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105784248","display_name":"Kaan Harmankaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"K. Harmankaya","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Siegel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"J. Siegel","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086481435","display_name":"Axel Hoos","orcid":"https://orcid.org/0000-0001-5269-9376","observed_orcids":["https://orcid.org/0000-0001-5269-9376"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"A. Hoos","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048698138","display_name":"Rachel W. Humphrey","orcid":"https://orcid.org/0009-0007-6425-675X","observed_orcids":["https://orcid.org/0009-0007-6425-675X"]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"R. Humphrey","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034331469","display_name":"J. D. Wolchok","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129774422","display_name":"University of Vienna","ror":"https://ror.org/03prydq77","country_code":"AT","type":"education","lineage":["https://openalex.org/I129774422"]},{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]},{"id":"https://openalex.org/I3019308854","display_name":"Moffitt Cancer Center","ror":"https://ror.org/01xf75524","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I3019308854"]},{"id":"https://openalex.org/I4210091812","display_name":"Bristol-Myers Squibb (United States)","ror":"https://ror.org/00gtmwv55","country_code":"US","type":"company","lineage":["https://openalex.org/I4210091812"]},{"id":"https://openalex.org/I4210104507","display_name":"Angeles Clinic and Research Institute","ror":"https://ror.org/01ct2ab72","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834","https://openalex.org/I4210104507"]},{"id":"https://openalex.org/I4210144610","display_name":"H\u00f4pital Saint-Louis","ror":"https://ror.org/049am9t04","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210144610"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT","FR","US"],"is_corresponding":false,"raw_author_name":"J. Wolchok","raw_affiliation_strings":["The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Angeles Clinic and Research Institute, Santa Monica, CA; H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Saint-Louis Hospital, Paris, France; University Hospital of Siena, Ist Toscano Tumori, Siena, Italy; University of Vienna, Vienna, Austria; University of Dermatology, Medical University of Vienna, Vienna, Austria; Bristol-Myers Squibb, Wallingford, CT; Bristol-Myers Squibb, Princeton, NJ; Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I129774422","https://openalex.org/I1334819555","https://openalex.org/I3019308854","https://openalex.org/I4210091812","https://openalex.org/I4210104507","https://openalex.org/I4210144610","https://openalex.org/I76134821"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"15_suppl","first_page":"9033","last_page":"9033"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ipilimumab","display_name":"ipilimumab","score":1.0},{"id":"https://openalex.org/keywords/advanced-melanoma","display_name":"advanced melanoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/long-term-survival","display_name":"long-term survival","score":0.7350000143051147},{"id":"https://openalex.org/keywords/ctla-4-blockade","display_name":"CTLA-4 blockade","score":0.9139999747276306},{"id":"https://openalex.org/keywords/immune-checkpoint-inhibitors","display_name":"immune checkpoint inhibitors","score":0.824999988079071},{"id":"https://openalex.org/keywords/previously-treated-patients","display_name":"previously treated patients","score":0.7229999899864197},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.7369999885559082},{"id":"https://openalex.org/keywords/maintenance-therapy","display_name":"maintenance therapy","score":0.5410000085830688},{"id":"https://openalex.org/keywords/budesonide","display_name":"budesonide","score":0.8529999852180481},{"id":"https://openalex.org/keywords/immune-related-adverse-events","display_name":"immune-related adverse events","score":0.9549999833106995}],"concepts":[{"id":"https://openalex.org/C2781433595","wikidata":"https://www.wikidata.org/wiki/Q2459042","display_name":"Ipilimumab","level":4,"score":0.9907453060150146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9326091408729553},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6439172625541687},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.5601885318756104},{"id":"https://openalex.org/C2777658100","wikidata":"https://www.wikidata.org/wiki/Q180614","display_name":"Melanoma","level":2,"score":0.5267742872238159},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4582601487636566},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.42395591735839844},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.36833471059799194},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34480875730514526},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3332425355911255},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.2799180746078491},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2009.27.15_suppl.9033","doi":"https://doi.org/10.1200/jco.2009.27.15_suppl.9033","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2009.27.15_suppl.9033","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2494190851","https://openalex.org/W7046928333","https://openalex.org/W2246726729","https://openalex.org/W2276033320","https://openalex.org/W2164281389","https://openalex.org/W2530644109","https://openalex.org/W2999327048","https://openalex.org/W2156261087","https://openalex.org/W4213289306","https://openalex.org/W2600931526"],"abstract_inverted_index":{"9033":[0],"Background:":[1],"The":[2,151,253],"monoclonal":[3],"antibody":[4],"ipilimumab":[5,23,42,53,79,85,102,137],"targets":[6],"cytotoxic":[7],"T":[8],"lymphocyte":[9],"antigen-4.":[10],"Updated":[11],"survival":[12,144,202,211,243,254],"data":[13,255],"(\u226432.5":[14],"months":[15,126],"follow-up)":[16],"from":[17,104,122,219],"3":[18,89,214],"Phase":[19,215],"II":[20,216],"trials":[21],"of":[22,41,52,66,69,153,166,234],"in":[24,76,176,199,204],"pts":[25,77,96,133,183,205,236,247],"with":[26,184,206,237],"mostly":[27],"pretreated":[28],"advanced":[29,207,238],"melanoma":[30,239],"are":[31,146],"reported.":[32],"Methods:":[33],"Study":[34,45,59],"CA184008":[35],"was":[36,47,61,86],"an":[37],"open-label,":[38],"single-arm":[39],"study":[40,51,65],"10":[43,57,80,135],"mg/kg.":[44,58,81],"CA184022":[46],"a":[48,62,118,163,200,241],"randomized,":[49,63],"dose-ranging":[50],"0.3,":[54],"3,":[55],"or":[56],"CA184007":[60],"placebo-controlled":[64],"the":[67,154,172],"effect":[68],"budesonide":[70],"on":[71],"gastrointestinal":[72],"immune-related":[73],"adverse":[74],"events":[75],"receiving":[78,134],"In":[82],"all":[83,177],"studies,":[84],"given":[87],"every":[88],"weeks":[90],"(Q3W)":[91],"\u00d7":[92],"4":[93],"(induction);":[94],"eligible":[95],"could":[97],"continue":[98,108,256],"to":[99,109,112,124,130,169,221,257],"receive":[100],"maintenance":[101],"Q12W":[103],"week":[105],"24.":[106],"Pts":[107],"be":[110],"followed-up":[111],"determine":[113],"long-term":[114,201,242],"survival.":[115],"Results:":[116],"With":[117],"median":[119],"follow-up":[120,174,260],"ranging":[121],"10.1":[123],"16.3":[125],"and":[127,142,259],"reaching":[128],"up":[129],"32.5+":[131],"months,":[132,160],"mg/kg":[136],"showed":[138],"durable":[139],"survival;":[140],"12-":[141],"18-month":[143,210],"rates":[145,212],"presented":[147],"[":[148],"Table":[149],"].":[150],"tail":[152],"Kaplan-Meier":[155],"curve":[156],"flattened":[157],"at":[158],"18":[159],"indicating":[161],"that":[162,230],"substantial":[164],"proportion":[165],"patients":[167],"continued":[168],"survive":[170],"beyond":[171],"updated":[173],"period":[175],"three":[178],"studies.":[179],"Long-term":[180],"survivors":[181],"include":[182],"disease":[185],"progression":[186],"(PD)":[187],"per":[188],"modified":[189],"World":[190],"Health":[191],"Organization":[192],"(mWHO)":[193],"criteria.":[194],"Conclusions:":[195],"Ipilimumab":[196],"may":[197],"result":[198],"benefit":[203],"melanoma,":[208],"where":[209],"across":[213],"studies":[217],"range":[218],"34.5%":[220],"39.4%":[222],"for":[223],"previously":[224],"treated":[225],"pts.":[226],"These":[227],"results":[228],"indicate":[229],"more":[231],"than":[232],"1/3":[233],"ipilimumab-treated":[235],"experience":[240],"benefit,":[244],"including":[245],"some":[246],"characterized":[248],"as":[249],"PD":[250],"by":[251],"mWHO.":[252],"mature,":[258],"is":[261],"ongoing.":[262],"[Table:":[263,266],"see":[264,267],"text]":[265,268]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}