{"id":"https://openalex.org/W2398367451","doi":"https://doi.org/10.1016/j.ymeth.2016.05.012","title":"Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments","display_name":"Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments","publication_year":2016,"publication_date":"2016-05-21","ids":{"openalex":"https://openalex.org/W2398367451","doi":"https://doi.org/10.1016/j.ymeth.2016.05.012","mag":"2398367451","pmid":"https://pubmed.ncbi.nlm.nih.gov/27211010","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12054381"},"language":"en","primary_location":{"id":"doi:10.1016/j.ymeth.2016.05.012","doi":"https://doi.org/10.1016/j.ymeth.2016.05.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ymeth.2016.05.012","pdf_url":null,"source":{"id":"https://openalex.org/S73539393","display_name":"Methods","issn_l":"1046-2023","issn":["1046-2023","1095-9130"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12054381","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067659955","display_name":"Ram\u00f3n Xulvi-Brunet","orcid":"https://orcid.org/0000-0002-6013-4831","observed_orcids":["https://orcid.org/0000-0002-6013-4831"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]},{"id":"https://openalex.org/I70764802","display_name":"National Polytechnic School","ror":"https://ror.org/01gb99w41","country_code":"EC","type":"education","lineage":["https://openalex.org/I70764802"]}],"countries":["EC","US"],"is_corresponding":true,"raw_author_name":"Ramon Xulvi-Brunet","raw_affiliation_strings":["Departamento de F\u00edsica, Facultad de Ciencias, Escuela Polit\u00e9cnica Nacional, Quito, Ecuador; Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA. Electronic address: ramon.xulvi@epn.edu.ec","Departamento de F\u00edsica, Facultad de Ciencias, Escuela Polit\u00e9cnica Nacional, Quito, Ecuador","Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de F\u00edsica, Facultad de Ciencias, Escuela Polit\u00e9cnica Nacional, Quito, Ecuador; Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA. Electronic address: ramon.xulvi@epn.edu.ec","institution_ids":["https://openalex.org/I154570441","https://openalex.org/I70764802"]},{"raw_affiliation_string":"Departamento de F\u00edsica, Facultad de Ciencias, Escuela Polit\u00e9cnica Nacional, Quito, Ecuador","institution_ids":["https://openalex.org/I70764802"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085819477","display_name":"Gregory W. Campbell","orcid":"https://orcid.org/0000-0002-8044-524X","observed_orcids":["https://orcid.org/0000-0002-8044-524X"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory W. Campbell","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031795137","display_name":"Sudha Rajamani","orcid":"https://orcid.org/0000-0002-6030-495X","observed_orcids":["https://orcid.org/0000-0002-6030-495X"]},"institutions":[{"id":"https://openalex.org/I181996519","display_name":"Indian Institute of Science Education and Research Pune","ror":"https://ror.org/028qa3n13","country_code":"IN","type":"education","lineage":["https://openalex.org/I181996519"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sudha Rajamani","raw_affiliation_strings":["Indian Institute of Science Education and Research, Pune, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indian Institute of Science Education and Research, Pune, India","institution_ids":["https://openalex.org/I181996519"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003235023","display_name":"Jos\u00e9 Ignacio Jim\u00e9nez","orcid":"https://orcid.org/0000-0002-2700-9473","observed_orcids":["https://orcid.org/0000-0002-2700-9473"]},"institutions":[{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jos\u00e9 I. Jim\u00e9nez","raw_affiliation_strings":["Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005967684","display_name":"Irene A. Chen","orcid":"https://orcid.org/0000-0001-6040-7927","observed_orcids":["https://orcid.org/0000-0001-6040-7927"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Irene A. Chen","raw_affiliation_strings":["Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA. Electronic address: chen@chem.ucsb.edu","Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA. Electronic address: chen@chem.ucsb.edu","institution_ids":["https://openalex.org/I154570441"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry, Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA","institution_ids":["https://openalex.org/I154570441"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5005967684","https://openalex.org/A5067659955"],"corresponding_institution_ids":["https://openalex.org/I154570441","https://openalex.org/I70764802"],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":0.8489,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.71846299,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"106","issue":null,"first_page":"86","last_page":"96"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.9208999872207642,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.9208999872207642,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.07490000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fitness-landscape","display_name":"fitness landscape","score":0.9160000085830688},{"id":"https://openalex.org/keywords/in-vitro-selection","display_name":"in vitro selection","score":0.7289999723434448},{"id":"https://openalex.org/keywords/evolutionary-networks","display_name":"evolutionary networks","score":0.7580000162124634},{"id":"https://openalex.org/keywords/bias-correction","display_name":"bias correction","score":0.7889999747276306},{"id":"https://openalex.org/keywords/sequence-spaces","display_name":"sequence spaces","score":0.7149999737739563},{"id":"https://openalex.org/keywords/galaxy-tool","display_name":"Galaxy tool","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C91852762","wikidata":"https://www.wikidata.org/wiki/Q3307742","display_name":"Fitness landscape","level":3,"score":0.7444658875465393},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.6745378971099854},{"id":"https://openalex.org/C30711495","wikidata":"https://www.wikidata.org/wiki/Q289411","display_name":"Sequence space","level":3,"score":0.6300140619277954},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.6257113218307495},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5844884514808655},{"id":"https://openalex.org/C2780801425","wikidata":"https://www.wikidata.org/wiki/Q5164392","display_name":"Construct (python library)","level":2,"score":0.5695195198059082},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5561462640762329},{"id":"https://openalex.org/C166393388","wikidata":"https://www.wikidata.org/wiki/Q856529","display_name":"Molecular evolution","level":4,"score":0.537310004234314},{"id":"https://openalex.org/C176066374","wikidata":"https://www.wikidata.org/wiki/Q629118","display_name":"Fitness function","level":3,"score":0.5212334394454956},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4987335205078125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4601263701915741},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.34113866090774536},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3050020933151245},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.27820566296577454},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18454191088676453},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.16528117656707764},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.14189967513084412},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10961970686912537},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C132954091","wikidata":"https://www.wikidata.org/wiki/Q194397","display_name":"Banach space","level":2,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.0},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019020","descriptor_name":"Directed Molecular Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D056084","descriptor_name":"Genetic Fitness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":8,"locations":[{"id":"doi:10.1016/j.ymeth.2016.05.012","doi":"https://doi.org/10.1016/j.ymeth.2016.05.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ymeth.2016.05.012","pdf_url":null,"source":{"id":"https://openalex.org/S73539393","display_name":"Methods","issn_l":"1046-2023","issn":["1046-2023","1095-9130"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods","raw_type":"journal-article"},{"id":"pmid:27211010","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27211010","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods (San Diego, Calif.)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:10866209","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12054381","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:12054381","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12054381/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Methods","raw_type":"Text"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt0mq040n4","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/0mq040n4","pdf_url":"https://escholarship.org/content/qt0mq040n4/qt0mq040n4.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Methods, vol 106","raw_type":"article"},{"id":"pmh:oai:epubs.surrey.ac.uk:810899","doi":null,"is_oa":false,"landing_page_url":"http://epubs.surrey.ac.uk/810899/1/45_2016__Roth-RefMod.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306400680","display_name":"Surrey Research Insight Open Access (The University of Surrey)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28290843","host_organization_name":"University of Surrey","host_organization_lineage":["https://openalex.org/I28290843"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt0mq040n4","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/0mq040n4","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:qt0mq040n4","doi":null,"is_oa":false,"landing_page_url":"http://www.escholarship.org/uc/item/0mq040n4","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Xulvi-Brunet, R; Campbell, GW; Rajamani, S; Jimenez, JI; & Chen, IA. (2016). Computational analysis of fitness landscapes and evolutionary networks from in vitro evolution experiments. METHODS, 106, 86 - 96. doi: 10.1016/j.ymeth.2016.05.012. UC Santa Barbara: Retrieved from: http://www.escholarship.org/uc/item/0mq040n4","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:10866209","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12054381","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1035847006","display_name":null,"funder_award_id":"DMR 1121053","funder_id":"https://openalex.org/F4320337367","funder_display_name":"Division of Materials Research"},{"id":"https://openalex.org/G1115769823","display_name":null,"funder_award_id":"W911NF-09-0001","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G2011250882","display_name":null,"funder_award_id":"290356","funder_id":"https://openalex.org/F4320306164","funder_display_name":"Simons Foundation"},{"id":"https://openalex.org/G226397104","display_name":null,"funder_award_id":"W911NF\u201009\u20100001","funder_id":"https://openalex.org/F4320338502","funder_display_name":"Institute for Collaborative Biotechnologies"},{"id":"https://openalex.org/G3010040163","display_name":null,"funder_award_id":"1121053","funder_id":"https://openalex.org/F4320333422","funder_display_name":"Materials Research Science and Engineering Center, Harvard University"},{"id":"https://openalex.org/G3771045958","display_name":"Biological Diversity: Generation, Control and Exploitation","funder_award_id":"P50GM068763","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G424939613","display_name":"The role of the cellular economics in the expression of exogenous genes: Towards modularity in synthetic circuit design.","funder_award_id":"BB/M009769/1","funder_id":"https://openalex.org/F4320334629","funder_display_name":"Biotechnology and Biological Sciences Research Council"},{"id":"https://openalex.org/G4705828600","display_name":"Center of Excellence for Materials Research and Innovation at UCSB","funder_award_id":"1121053","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G503935606","display_name":null,"funder_award_id":"DMR-1121053","funder_id":"https://openalex.org/F4320333422","funder_display_name":"Materials Research Science and Engineering Center, Harvard University"},{"id":"https://openalex.org/G504240244","display_name":"MRI-R2: Acquisition of a high performance central computing facility at UCSB","funder_award_id":"0960316","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7452299184","display_name":null,"funder_award_id":"W911NF","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G7498246471","display_name":null,"funder_award_id":"1121053","funder_id":"https://openalex.org/F4320337367","funder_display_name":"Division of Materials Research"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306164","display_name":"Simons Foundation","ror":"https://ror.org/01cmst727"},{"id":"https://openalex.org/F4320314849","display_name":"Searle Scholars Program","ror":null},{"id":"https://openalex.org/F4320324168","display_name":"Indian Institute of Science Education and Research Pune","ror":"https://ror.org/028qa3n13"},{"id":"https://openalex.org/F4320327182","display_name":"Indian Institute of Science Education and Research Mohali","ror":"https://ror.org/01vztzd79"},{"id":"https://openalex.org/F4320333422","display_name":"Materials Research Science and Engineering Center, Harvard University","ror":"https://ror.org/01qa5ep47"},{"id":"https://openalex.org/F4320334629","display_name":"Biotechnology and Biological Sciences Research Council","ror":"https://ror.org/00cwqg982"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337367","display_name":"Division of Materials Research","ror":"https://ror.org/01pc7k308"},{"id":"https://openalex.org/F4320337965","display_name":"California NanoSystems Institute","ror":"https://ror.org/00q7fqf35"},{"id":"https://openalex.org/F4320338281","display_name":"Army Research Office","ror":"https://ror.org/05epdh915"},{"id":"https://openalex.org/F4320338502","display_name":"Institute for Collaborative Biotechnologies","ror":"https://ror.org/04kz4p343"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2398367451.pdf","grobid_xml":"https://content.openalex.org/works/W2398367451.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1566430606","https://openalex.org/W1647671624","https://openalex.org/W1680571683","https://openalex.org/W1969857637","https://openalex.org/W1976647752","https://openalex.org/W1980073965","https://openalex.org/W1984668659","https://openalex.org/W1991524704","https://openalex.org/W1992613346","https://openalex.org/W1999599455","https://openalex.org/W2001496424","https://openalex.org/W2006539489","https://openalex.org/W2009435671","https://openalex.org/W2010635656","https://openalex.org/W2019765512","https://openalex.org/W2032433599","https://openalex.org/W2042733284","https://openalex.org/W2044807855","https://openalex.org/W2051853521","https://openalex.org/W2079321730","https://openalex.org/W2084443943","https://openalex.org/W2087464200","https://openalex.org/W2104525153","https://openalex.org/W2105368763","https://openalex.org/W2106602737","https://openalex.org/W2131088968","https://openalex.org/W2139658365","https://openalex.org/W2142565931","https://openalex.org/W2148612363","https://openalex.org/W2159675211","https://openalex.org/W2161645441","https://openalex.org/W2166859993","https://openalex.org/W2230768852","https://openalex.org/W2342204193","https://openalex.org/W2401382811","https://openalex.org/W2479673329","https://openalex.org/W2493416933","https://openalex.org/W2612166593","https://openalex.org/W3148930403","https://openalex.org/W7064205038"],"related_works":["https://openalex.org/W2125568194","https://openalex.org/W2032433599","https://openalex.org/W6910897098","https://openalex.org/W2051853521","https://openalex.org/W4400678160","https://openalex.org/W2088941898","https://openalex.org/W7047011896","https://openalex.org/W2907627192","https://openalex.org/W1982940904","https://openalex.org/W7000344403"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}