{"id":"https://openalex.org/W2398333345","doi":"https://doi.org/10.1055/s-2003-43223","title":"Iridoid Glucosides from the Flowers ofBarleria lupulina","display_name":"Iridoid Glucosides from the Flowers ofBarleria lupulina","publication_year":2003,"publication_date":"2003-09-01","ids":{"openalex":"https://openalex.org/W2398333345","doi":"https://doi.org/10.1055/s-2003-43223","mag":"2398333345","pmid":"https://pubmed.ncbi.nlm.nih.gov/14598223"},"language":"en","primary_location":{"id":"doi:10.1055/s-2003-43223","doi":"https://doi.org/10.1055/s-2003-43223","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2003-43223","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083249595","display_name":"Sunit Suksamrarn","orcid":"https://orcid.org/0000-0002-8432-6475","observed_orcids":["https://orcid.org/0000-0002-8432-6475"]},"institutions":[{"id":"https://openalex.org/I76920116","display_name":"Srinakharinwirot University","ror":"https://ror.org/04718hx42","country_code":"TH","type":"education","lineage":["https://openalex.org/I76920116"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Sunit\u00a0Suksamrarn","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand","institution_ids":["https://openalex.org/I76920116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053778455","display_name":"Kanjana Wongkrajang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58196637","display_name":"Ramkhamhaeng University","ror":"https://ror.org/00mrw8k38","country_code":"TH","type":"education","lineage":["https://openalex.org/I58196637"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Kanjana\u00a0Wongkrajang","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand","institution_ids":["https://openalex.org/I58196637"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021785316","display_name":"Kanyawim Kirtikara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1332092204","display_name":"National Science and Technology Development Agency","ror":"https://ror.org/04vy95b61","country_code":"TH","type":"government","lineage":["https://openalex.org/I1332092204"]},{"id":"https://openalex.org/I902798049","display_name":"National Center for Genetic Engineering and Biotechnology","ror":"https://ror.org/047aswc67","country_code":"TH","type":"facility","lineage":["https://openalex.org/I1332092204","https://openalex.org/I902798049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Kanyawim\u00a0Kirtikara","raw_affiliation_strings":["National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathumthani, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Center for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathumthani, Thailand","institution_ids":["https://openalex.org/I1332092204","https://openalex.org/I902798049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026011880","display_name":"Apichart Suksamrarn","orcid":"https://orcid.org/0000-0001-8919-3555","observed_orcids":["https://orcid.org/0000-0001-8919-3555"]},"institutions":[{"id":"https://openalex.org/I58196637","display_name":"Ramkhamhaeng University","ror":"https://ror.org/00mrw8k38","country_code":"TH","type":"education","lineage":["https://openalex.org/I58196637"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Apichart\u00a0Suksamrarn","raw_affiliation_strings":["Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand","institution_ids":["https://openalex.org/I58196637"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6284,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.83809703,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"69","issue":"9","first_page":"877","last_page":"879"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13185","display_name":"Phytochemistry and Bioactive Compounds","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/barleria-lupulina","display_name":"Barleria lupulina","score":0.9269999861717224},{"id":"https://openalex.org/keywords/iridoid-glucosides","display_name":"iridoid glucosides","score":0.968999981880188},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.7979999780654907},{"id":"https://openalex.org/keywords/antiviral-activity","display_name":"antiviral activity","score":0.8679999709129333},{"id":"https://openalex.org/keywords/cox-2-inhibition","display_name":"COX-2 inhibition","score":0.9100000262260437},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9440000057220459}],"concepts":[{"id":"https://openalex.org/C2778413156","wikidata":"https://www.wikidata.org/wiki/Q416840","display_name":"Iridoid","level":3,"score":0.8261896967887878},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.5974060297012329},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5258976817131042},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4817492961883545},{"id":"https://openalex.org/C89138240","wikidata":"https://www.wikidata.org/wiki/Q3066564","display_name":"Vero cell","level":3,"score":0.41603487730026245},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28650426864624023},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18353456258773804},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.08323460817337036},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.04310649633407593}],"mesh":[{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008517","descriptor_name":"Phytotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D018259","descriptor_name":"Herpesvirus 1, Human","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D027901","descriptor_name":"Acanthaceae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035264","descriptor_name":"Flowers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D039823","descriptor_name":"Iridoids","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D039823","descriptor_name":"Iridoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D039823","descriptor_name":"Iridoids","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1055/s-2003-43223","doi":"https://doi.org/10.1055/s-2003-43223","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-2003-43223","pdf_url":null,"source":{"id":"https://openalex.org/S39653451","display_name":"Planta Medica","issn_l":"0032-0943","issn":["0032-0943","1439-0221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320000","host_organization_name":"Thieme Medical Publishers (Germany)","host_organization_lineage":["https://openalex.org/P4310320000"],"host_organization_lineage_names":["Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta Medica","raw_type":"journal-article"},{"id":"pmid:14598223","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14598223","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Planta medica","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2022330334","https://openalex.org/W2061227696","https://openalex.org/W2317962474","https://openalex.org/W4409471581","https://openalex.org/W2265312373","https://openalex.org/W2324664803","https://openalex.org/W2042915302","https://openalex.org/W2056469065","https://openalex.org/W4391554827","https://openalex.org/W2803707691"],"abstract_inverted_index":{"A":[0],"new":[1,39],"iridoid":[2,8],"diglucoside,":[3],"lupulinoside,":[4],"and":[5,24,77],"eight":[6],"known":[7],"glucosides,":[9],"acetylbarlerin,":[10],"ipolamiidoside":[11],"(":[12],"3),":[13],"6-O-acetylshanzhiside":[14],"methyl":[15,19],"ester,":[16,20],"barlerin,":[17],"shanzhiside":[18,25],"mussaenosidic":[21],"acid,":[22],"8-O-acetylshanzhiside,":[23],"have":[26],"been":[27],"isolated":[28],"from":[29],"the":[30,38,68,74],"flowers":[31],"of":[32,37,67,79],"Barleria":[33],"lupulina.":[34],"The":[35],"structure":[36],"compound":[40,61],"was":[41],"established":[42],"as":[43],"8-O-acetyl-2'-":[44],"O-(beta-glucopyranosyl)mussaenoside":[45],"by":[46],"spectroscopic,":[47],"especially":[48],"2D":[49],"NMR,":[50],"techniques.":[51],"When":[52],"tested":[53],"for":[54],"anti-herpes":[55],"simplex":[56],"type":[57],"1":[58],"activity,":[59],"only":[60],"3":[62],"exhibited":[63],"antiviral":[64],"properties.":[65],"None":[66],"compounds":[69],"showed":[70],"cytotoxic":[71],"effects":[72],"to":[73],"vero":[75],"cells":[76],"none":[78],"them":[80],"inhibited":[81],"cyclooxygenase-2":[82],"enzyme.":[83]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}