{"id":"https://openalex.org/W2398252014","doi":null,"title":"Mouse mammary tumor proviral gene expression in cells of the B lineage.","display_name":"Mouse mammary tumor proviral gene expression in cells of the B lineage.","publication_year":1992,"publication_date":"1992-10-01","ids":{"openalex":"https://openalex.org/W2398252014","mag":"2398252014","pmid":"https://pubmed.ncbi.nlm.nih.gov/1336679"},"language":"en","primary_location":{"id":"pmid:1336679","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1336679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in immunology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030201904","display_name":"Ronald B. Corley","orcid":"https://orcid.org/0000-0002-7498-0545","observed_orcids":["https://orcid.org/0000-0002-7498-0545"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R B Corley","raw_affiliation_strings":["Department of Immunology, Duke University Medical Center, Durham, NC 27710"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Duke University Medical Center, Durham, NC 27710","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060797804","display_name":"Frances E. Lund","orcid":"https://orcid.org/0000-0003-3083-1246","observed_orcids":["https://orcid.org/0000-0003-3083-1246"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F E Lund","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000051455","display_name":"Troy D. Randall","orcid":"https://orcid.org/0000-0003-0643-0311","observed_orcids":["https://orcid.org/0000-0003-0643-0311"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T D Randall","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052600482","display_name":"King Lb","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L B King","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070491394","display_name":"Stefan Doerre","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Doerre","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5080784954","display_name":"David L. Woodland","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D L Woodland","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6705,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.65801092,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":"5","first_page":"287","last_page":"96"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.5781000256538391,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.5781000256538391,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.27469998598098755,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.026100000366568565,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mouse-mammary-tumor-virus","display_name":"mouse mammary tumor virus","score":0.9909999966621399},{"id":"https://openalex.org/keywords/proviral-gene-expression","display_name":"proviral gene expression","score":0.9070000052452087},{"id":"https://openalex.org/keywords/b-cells","display_name":"B cells","score":0.8040000200271606},{"id":"https://openalex.org/keywords/hormone-response-elements","display_name":"hormone response elements","score":0.9039999842643738},{"id":"https://openalex.org/keywords/5-long-terminal-repeat","display_name":"5' long terminal repeat","score":0.824999988079071},{"id":"https://openalex.org/keywords/3-long-terminal-repeat","display_name":"3' long terminal repeat","score":0.9190000295639038},{"id":"https://openalex.org/keywords/open-reading-frames","display_name":"open reading frames","score":0.8349999785423279},{"id":"https://openalex.org/keywords/superantigens","display_name":"superantigens","score":0.828000009059906},{"id":"https://openalex.org/keywords/autoregulation","display_name":"autoregulation","score":0.8130000233650208},{"id":"https://openalex.org/keywords/transcriptional-activation","display_name":"transcriptional activation","score":0.7979999780654907},{"id":"https://openalex.org/keywords/b-cell-activation","display_name":"B cell activation","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C2779777497","wikidata":"https://www.wikidata.org/wiki/Q1775519","display_name":"Mouse mammary tumor virus","level":3,"score":0.7600165009498596},{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.7518777251243591},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6870430111885071},{"id":"https://openalex.org/C199491388","wikidata":"https://www.wikidata.org/wiki/Q1869477","display_name":"Long terminal repeat","level":4,"score":0.6766132116317749},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.6405723690986633},{"id":"https://openalex.org/C1292079","wikidata":"https://www.wikidata.org/wiki/Q3817769","display_name":"Transactivation","level":4,"score":0.6246213912963867},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5079835057258606},{"id":"https://openalex.org/C47289529","wikidata":"https://www.wikidata.org/wiki/Q908550","display_name":"Open reading frame","level":4,"score":0.4925921559333801},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4613857567310333},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.401489794254303},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3481009006500244},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32702362537384033},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.21395015716552734},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000957","descriptor_name":"Antigens, Viral, Tumor","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005814","descriptor_name":"Genes, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008324","descriptor_name":"Mammary Tumor Virus, Mouse","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011533","descriptor_name":"Proviruses","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012091","descriptor_name":"Repetitive Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015533","descriptor_name":"Transcriptional Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016366","descriptor_name":"Open Reading Frames","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1336679","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1336679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seminars in immunology","raw_type":"Journal Article"},{"id":"mag:2398252014","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1336679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1171351707","display_name":"CELLULAR AND MOLECULAR EVENTS IN B LYMPHOCYTE ACTIVATION","funder_award_id":"R01CA036642","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3010207925","display_name":"Organization and Function of Cellular Structure","funder_award_id":"T32GM007184","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000904664","display_name":"Cancer Center Support Grant (CCSG)","funder_award_id":"P30CA021765","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1975272993","https://openalex.org/W2102548557","https://openalex.org/W2107497182","https://openalex.org/W1583661613","https://openalex.org/W1798195426","https://openalex.org/W2099619063","https://openalex.org/W2022748435","https://openalex.org/W6454207","https://openalex.org/W1801713977","https://openalex.org/W2102455772"],"abstract_inverted_index":{"Mouse":[0],"mammary":[1,20],"tumor":[2],"proviruses":[3],"(MMTV)":[4],"use":[5,103],"a":[6,82,96],"common":[7],"enhancer/promoter":[8],"region":[9],"to":[10,91,102],"accommodate":[11],"their":[12],"transcription":[13,22,38,54],"in":[14,31,67,110],"two":[15,75],"different":[16],"cellular":[17],"environments.":[18],"In":[19,35],"tissue,":[21],"is":[23,39,50],"regulated":[24],"through":[25],"the":[26,32,53,68,104],"hormone":[27,40],"response":[28],"element":[29],"located":[30],"5'":[33],"LTR.":[34],"B":[36,46,105],"cells,":[37],"independent,":[41],"can":[42],"be":[43],"stimulated":[44],"following":[45],"cell":[47,106],"activation,":[48],"and":[49],"distinct":[51],"from":[52],"of":[55],"other":[56],"known":[57],"inducible":[58],"genes,":[59],"including":[60],"immunoglobulin.":[61],"The":[62],"open":[63],"reading":[64],"frame":[65],"(ORF)":[66],"viral":[69,83,112],"3'":[70],"LTR":[71],"has":[72,87],"at":[73],"least":[74],"functions.":[76],"Its":[77],"gene":[78],"product(s)":[79],"acts":[80],"as":[81,107],"superantigen,":[84],"but":[85],"also":[86],"autoregulatory":[88],"properties,":[89],"leading":[90],"MMTV":[92,100],"transactivation.":[93],"We":[94],"propose":[95],"scheme":[97],"suggesting":[98],"that":[99],"evolved":[101],"an":[108],"intermediary":[109],"its":[111],"life":[113],"cycle.":[114]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}