{"id":"https://openalex.org/W2397877517","doi":"https://doi.org/10.1385/0-89603-516-6:85","title":"ln Situ Photopolymerized Hydrogels for Vascular and Peritoneal Wound Healing","display_name":"ln Situ Photopolymerized Hydrogels for Vascular and Peritoneal Wound Healing","publication_year":2003,"publication_date":"2003-11-14","ids":{"openalex":"https://openalex.org/W2397877517","doi":"https://doi.org/10.1385/0-89603-516-6:85","mag":"2397877517","pmid":"https://pubmed.ncbi.nlm.nih.gov/21370170"},"language":"en","primary_location":{"id":"doi:10.1385/0-89603-516-6:85","doi":"https://doi.org/10.1385/0-89603-516-6:85","is_oa":false,"landing_page_url":"https://doi.org/10.1385/0-89603-516-6:85","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4251989715","display_name":"Tissue Engineering"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042707187","display_name":"Amarpreet S. Sawhney","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amarpreet S. Sawhney","raw_affiliation_strings":["Focal Inc., Lexington, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Focal Inc., Lexington, MA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031517705","display_name":"Jeffrey A. Hubbell","orcid":"https://orcid.org/0000-0003-0276-5456","observed_orcids":["https://orcid.org/0000-0003-0276-5456"]},"institutions":[{"id":"https://openalex.org/I122411786","display_name":"California Institute of Technology","ror":"https://ror.org/05dxps055","country_code":"US","type":"education","lineage":["https://openalex.org/I122411786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey A. Hubbell","raw_affiliation_strings":["Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA","institution_ids":["https://openalex.org/I122411786"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.16883117,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"18","issue":null,"first_page":"85","last_page":"100"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12089","display_name":"Intestinal and Peritoneal Adhesions","score":0.3889000117778778,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12089","display_name":"Intestinal and Peritoneal Adhesions","score":0.3889000117778778,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.2992999851703644,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.21240000426769257,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/postoperative-adhesions","display_name":"postoperative adhesions","score":0.8650000095367432},{"id":"https://openalex.org/keywords/mesothelial-cells","display_name":"mesothelial cells","score":0.828000009059906},{"id":"https://openalex.org/keywords/fibrinolytic-activity","display_name":"fibrinolytic activity","score":0.8029999732971191},{"id":"https://openalex.org/keywords/pelvic-cavity","display_name":"pelvic cavity","score":0.5860000252723694},{"id":"https://openalex.org/keywords/adhesion-prevention","display_name":"adhesion prevention","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C2777822432","wikidata":"https://www.wikidata.org/wiki/Q216681","display_name":"In situ","level":2,"score":0.689816415309906},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.6187921166419983},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.6117058992385864},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.38733339309692383},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3279625177383423},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.32091212272644043},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3011241555213928},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.15851598978042603},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.15728822350502014},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1385/0-89603-516-6:85","doi":"https://doi.org/10.1385/0-89603-516-6:85","is_oa":false,"landing_page_url":"https://doi.org/10.1385/0-89603-516-6:85","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue Engineering","raw_type":"book-chapter"},{"id":"pmid:21370170","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21370170","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in molecular medicine","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1999742367","https://openalex.org/W2002848795","https://openalex.org/W2012801001","https://openalex.org/W2039010543","https://openalex.org/W2042284290","https://openalex.org/W2047841957","https://openalex.org/W2069099749","https://openalex.org/W2070720377","https://openalex.org/W2077644034","https://openalex.org/W2096133301","https://openalex.org/W2096746881","https://openalex.org/W2148371225"],"related_works":["https://openalex.org/W2064796928","https://openalex.org/W47154932","https://openalex.org/W2293816302","https://openalex.org/W3147540560","https://openalex.org/W2147550866","https://openalex.org/W6997898027","https://openalex.org/W3158401918","https://openalex.org/W2525683625","https://openalex.org/W7098018139","https://openalex.org/W2029205214"],"abstract_inverted_index":{"The":[0,182],"process":[1],"of":[2,58,72,86,107,121,135,143,184,194],"wound":[3,27,33],"healing":[4,18,124],"in":[5,14,19,43,113,201,208],"internal":[6],"organs":[7,42,112],"lined":[8],"with":[9,160],"mesothelial":[10,49,89],"cells":[11],"is":[12,66,117,137,152,157],"different":[13],"some":[15],"respects":[16],"from":[17,31,60],"cutaneous":[20,26],"injuries.":[21],"Hertzler":[22],"(1)":[23],"noted":[24],"that":[25,51,69,92,132,215],"re-epithelialization":[28],"takes":[29],"place":[30,77],"the":[32,44,70,73,95,105,114,133,188],"borders,":[34],"but":[35],"peritoneal":[36],"defects":[37],"become":[38],"re-mesothelialized":[39],"simultaneously.":[40],"Most":[41],"pelvic":[45,115,203],"cavity":[46],"possess":[47],"a":[48,56,122],"lining":[50],"can":[52,75,93,180,186],"be":[53,225],"injured":[54],"as":[55,173],"result":[57,120],"trauma":[59],"surgical":[61,148],"intervention":[62],"or":[63,104,156],"handling.":[64],"It":[65],"generally":[67],"agreed":[68],"remesothelialization":[71,179],"peritoneum":[74],"take":[76],"over":[78],"5-8":[79],"d":[80],"(2).":[81],"During":[82],"this":[83],"period,":[84],"events":[85],"inflammation":[87],"and":[88,141,171,191,196,205,222],"repair":[90],"occur":[91],"set":[94],"course":[96],"for":[97],"postsurgical":[98],"adhesion":[99,102,176,218],"formation.":[100],"Postsurgical":[101],"formation,":[103,219],"formation":[106,177,183],"scar":[108],"tissue":[109,220],"bridges":[110],"between":[111],"cavity,":[116],"an":[118],"undesirable":[119],"natural":[123,192],"process.":[125],"Ryan":[126,213],"et":[127],"al.":[128],"(3)":[129],"showed":[130],"experimentally":[131],"surface":[134,164],"bowel":[136,206],"subject":[138],"to":[139,154,169,175,210,216],"demesothelialization":[140],"loss":[142],"native":[144],"fibrinolytic":[145],"activity":[146],"by":[147],"manipulation,":[149],"whether":[150],"it":[151],"allowed":[153],"dry":[155],"kept":[158],"moist":[159],"saline.":[161],"This":[162],"denuded":[163],"could":[165],"allow":[166],"blood":[167],"clots":[168],"form":[170],"act":[172],"precursors":[174],"before":[178],"occur.":[181],"adhesions":[185],"distort":[187],"normal":[189],"anatomy":[190],"positioning":[193],"organs,":[195],"has":[197],"often":[198],"been":[199],"implicated":[200],"postoperative":[202],"pain":[204],"obstructions,":[207],"addition":[209],"other":[211],"complications.":[212],"recommended":[214],"minimize":[217],"exposure":[221],"manipulation":[223],"should":[224],"minimized":[226],"(3).":[227]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}