{"id":"https://openalex.org/W2397866546","doi":"https://doi.org/10.1016/b978-0-12-374279-7.01007-9","title":"Regulation of Igh Recombination and Allelic Exclusion","display_name":"Regulation of Igh Recombination and Allelic Exclusion","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2397866546","doi":"https://doi.org/10.1016/b978-0-12-374279-7.01007-9","mag":"2397866546"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-374279-7.01007-9","doi":"https://doi.org/10.1016/b978-0-12-374279-7.01007-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-374279-7.01007-9","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Encyclopedia of Immunobiology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2809087370","display_name":"Encyclopedia of Immunobiology"},"type":"reference-entry","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101983103","display_name":"Bingtao Hao","orcid":"https://orcid.org/0000-0003-1997-9338","observed_orcids":["https://orcid.org/0000-0003-1997-9338"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bingtao Hao","raw_affiliation_strings":["New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083464518","display_name":"Jane A. Skok","orcid":"https://orcid.org/0000-0002-4145-1516","observed_orcids":["https://orcid.org/0000-0002-4145-1516"]},"institutions":[{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane A. Skok","raw_affiliation_strings":["New York University School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I57206974"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"64","last_page":"70"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8051999807357788,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8051999807357788,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.11949999630451202,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.04439999908208847,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allelic-exclusion","display_name":"allelic exclusion","score":0.953000009059906},{"id":"https://openalex.org/keywords/v-d-j-recombination","display_name":"V(D)J recombination","score":0.9940000176429749},{"id":"https://openalex.org/keywords/immunoglobulin-heavy-chain-locus","display_name":"immunoglobulin heavy chain locus","score":0.7409999966621399},{"id":"https://openalex.org/keywords/antigen-receptor-diversity","display_name":"antigen receptor diversity","score":0.6579999923706055},{"id":"https://openalex.org/keywords/b-cell-development","display_name":"B cell development","score":0.8140000104904175},{"id":"https://openalex.org/keywords/t-cell-receptor-gene-rearrangement","display_name":"T-cell receptor gene rearrangement","score":0.7160000205039978},{"id":"https://openalex.org/keywords/recombination-regulation","display_name":"recombination regulation","score":0.6039999723434448},{"id":"https://openalex.org/keywords/adaptive-immune-response","display_name":"adaptive immune response","score":0.5389999747276306}],"concepts":[{"id":"https://openalex.org/C2778794311","wikidata":"https://www.wikidata.org/wiki/Q2348651","display_name":"Allelic exclusion","level":5,"score":0.9121743440628052},{"id":"https://openalex.org/C102414288","wikidata":"https://www.wikidata.org/wiki/Q1172461","display_name":"Recombinase","level":4,"score":0.7918285131454468},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7030366063117981},{"id":"https://openalex.org/C2780254951","wikidata":"https://www.wikidata.org/wiki/Q1093098","display_name":"V(D)J recombination","level":4,"score":0.6603790521621704},{"id":"https://openalex.org/C113646796","wikidata":"https://www.wikidata.org/wiki/Q50263283","display_name":"Recombination-activating gene","level":4,"score":0.5724457502365112},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5347887873649597},{"id":"https://openalex.org/C156695909","wikidata":"https://www.wikidata.org/wiki/Q3373825","display_name":"Recombination","level":3,"score":0.5339177250862122},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5195974707603455},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.48337286710739136},{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.4339163601398468},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.42052942514419556},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4130227565765381},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4044688642024994},{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.35722628235816956},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.30764496326446533},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.2738727927207947}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-12-374279-7.01007-9","doi":"https://doi.org/10.1016/b978-0-12-374279-7.01007-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-374279-7.01007-9","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Encyclopedia of Immunobiology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W166696829","https://openalex.org/W1497130717","https://openalex.org/W1558693371","https://openalex.org/W1730627473","https://openalex.org/W1767627963","https://openalex.org/W1963762432","https://openalex.org/W1966254031","https://openalex.org/W1967542553","https://openalex.org/W1968554285","https://openalex.org/W1970174129","https://openalex.org/W1972534296","https://openalex.org/W1980546626","https://openalex.org/W1980889239","https://openalex.org/W1988096153","https://openalex.org/W1995955910","https://openalex.org/W1999287382","https://openalex.org/W2004042867","https://openalex.org/W2004271214","https://openalex.org/W2008820555","https://openalex.org/W2012614480","https://openalex.org/W2018107989","https://openalex.org/W2032288627","https://openalex.org/W2039653017","https://openalex.org/W2042398661","https://openalex.org/W2046019412","https://openalex.org/W2046107927","https://openalex.org/W2047123366","https://openalex.org/W2067651011","https://openalex.org/W2067706475","https://openalex.org/W2068030382","https://openalex.org/W2068660936","https://openalex.org/W2070922440","https://openalex.org/W2077665121","https://openalex.org/W2080563929","https://openalex.org/W2085110456","https://openalex.org/W2098660045","https://openalex.org/W2099984871","https://openalex.org/W2107243811","https://openalex.org/W2125089785","https://openalex.org/W2129883110","https://openalex.org/W2133051120","https://openalex.org/W2143351999","https://openalex.org/W2144756059","https://openalex.org/W2151925648","https://openalex.org/W2159241107","https://openalex.org/W2161251010","https://openalex.org/W2165362955","https://openalex.org/W2170694208"],"related_works":["https://openalex.org/W204160545","https://openalex.org/W2101868807","https://openalex.org/W7100456078","https://openalex.org/W1795104046","https://openalex.org/W2049389954","https://openalex.org/W1976410443","https://openalex.org/W1972589201","https://openalex.org/W1985028434","https://openalex.org/W2044998864","https://openalex.org/W2401462321"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}