{"id":"https://openalex.org/W2397728647","doi":null,"title":"Acanthosis nigricans and hyperandrogenism in a pregnancy complicated by diabetes.","display_name":"Acanthosis nigricans and hyperandrogenism in a pregnancy complicated by diabetes.","publication_year":1993,"publication_date":"1993-05-01","ids":{"openalex":"https://openalex.org/W2397728647","mag":"2397728647","pmid":"https://pubmed.ncbi.nlm.nih.gov/8469481"},"language":"en","primary_location":{"id":"pmid:8469481","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8469481","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Case Reports"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087947477","display_name":"Ofer Gemer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802646120","display_name":"Barzilai Medical Center","ror":"https://ror.org/00hmeez77","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2802646120"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"O Gemer","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Barzilai Medical Center, Ashkelon, Israel","institution_ids":["https://openalex.org/I2802646120"]}]},{"author_position":"middle","author":{"id":null,"display_name":"S Segal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Segal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113936787","display_name":"Octav Segal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"O Segal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112478959","display_name":"E. Zohav","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Zohav","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5064067862","display_name":"Essi Sassoon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Sassoon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4891,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.56972852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"81","issue":"5 ( Pt 2)","first_page":"810","last_page":"1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12433","display_name":"Skin Diseases and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12433","display_name":"Skin Diseases and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10673","display_name":"Gestational Diabetes Research and Management","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acanthosis-nigricans","display_name":"acanthosis nigricans","score":1.0},{"id":"https://openalex.org/keywords/hyperandrogenism","display_name":"hyperandrogenism","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gestational-diabetes-mellitus","display_name":"gestational diabetes mellitus","score":0.7440000176429749},{"id":"https://openalex.org/keywords/insulin-resistance-in-pregnancy","display_name":"insulin resistance in pregnancy","score":0.8840000033378601},{"id":"https://openalex.org/keywords/free-testosterone","display_name":"free testosterone","score":0.8510000109672546},{"id":"https://openalex.org/keywords/insulin-requirement","display_name":"insulin requirement","score":0.5},{"id":"https://openalex.org/keywords/postpartum-resolution","display_name":"postpartum resolution","score":0.7099999785423279},{"id":"https://openalex.org/keywords/skin-lesions","display_name":"skin lesions","score":0.5410000085830688}],"concepts":[{"id":"https://openalex.org/C2777705978","wikidata":"https://www.wikidata.org/wiki/Q415833","display_name":"Acanthosis nigricans","level":4,"score":0.9940404891967773},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9186716079711914},{"id":"https://openalex.org/C2780186808","wikidata":"https://www.wikidata.org/wiki/Q10529545","display_name":"Hyperandrogenism","level":5,"score":0.8102610111236572},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7317206859588623},{"id":"https://openalex.org/C2779434492","wikidata":"https://www.wikidata.org/wiki/Q126691","display_name":"Gestational diabetes","level":4,"score":0.6310890913009644},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6159628629684448},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5916640162467957},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5593337416648865},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5263606309890747},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5216544270515442},{"id":"https://openalex.org/C2780473172","wikidata":"https://www.wikidata.org/wiki/Q5572518","display_name":"Glycemic","level":3,"score":0.4284188151359558},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.3700513243675232},{"id":"https://openalex.org/C3018442814","wikidata":"https://www.wikidata.org/wiki/Q500816","display_name":"Polycystic ovary","level":4,"score":0.06445881724357605},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000052","descriptor_name":"Acanthosis Nigricans","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011254","descriptor_name":"Pregnancy in Diabetics","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:8469481","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8469481","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Case Reports"},{"id":"mag:2397728647","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8469481","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W193821100","https://openalex.org/W71577206","https://openalex.org/W2289045335","https://openalex.org/W2089024159","https://openalex.org/W4414261877","https://openalex.org/W1985599442","https://openalex.org/W2033662178","https://openalex.org/W2090695816","https://openalex.org/W164140458","https://openalex.org/W2039564380"],"abstract_inverted_index":{"BACKGROUND:":[0],"Acanthosis":[1],"nigricans":[2,66],"and":[3,68,93],"hyperandrogenism":[4],"have":[5,18],"been":[6,20],"associated":[7],"with":[8,37],"diabetes":[9,38],"mellitus":[10,39],"accompanied":[11],"by":[12],"insulin":[13,29,42,54,91],"resistance.":[14],"However,":[15],"these":[16],"manifestations":[17,77],"rarely":[19],"reported":[21],"to":[22,57],"occur":[23],"as":[24],"a":[25,86],"result":[26],"of":[27,31,51,64],"the":[28],"resistance":[30,43,92],"pregnancy.":[32,45],"CASE:":[33],"A":[34],"31-year-old":[35],"woman":[36],"exhibited":[40],"severe":[41],"during":[44],"At":[46],"32":[47],"weeks,":[48],"daily":[49],"administration":[50],"500":[52],"U":[53],"was":[55],"required":[56],"maintain":[58],"glycemic":[59],"control.":[60],"Skin":[61],"lesions":[62],"typical":[63],"acanthosis":[65,94],"appeared,":[67],"free":[69],"testosterone":[70],"levels":[71],"were":[72],"elevated":[73],"(10.3":[74],"pg/mL).":[75],"These":[76],"resolved":[78],"after":[79],"delivery.":[80],"CONCLUSION:":[81],"This":[82],"case":[83],"may":[84],"demonstrate":[85],"correlation":[87],"between":[88],"reversible":[89],"gestational":[90],"nigricans.":[95]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}