{"id":"https://openalex.org/W2397617233","doi":null,"title":"Hyperinsulinaemia is associated with development of electrocardiographic abnormalities in diabetics.","display_name":"Hyperinsulinaemia is associated with development of electrocardiographic abnormalities in diabetics.","publication_year":1984,"publication_date":"1984-09-01","ids":{"openalex":"https://openalex.org/W2397617233","mag":"2397617233","pmid":"https://pubmed.ncbi.nlm.nih.gov/6397290"},"language":"en","primary_location":{"id":"pmid:6397290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6397290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes research (Edinburgh, Scotland)","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050600762","display_name":"Hillson Rm","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R M Hillson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108810202","display_name":"T. D. R. Hockaday","orcid":"https://orcid.org/0009-0008-3974-2921","observed_orcids":["https://orcid.org/0009-0008-3974-2921"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T D Hockaday","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008309870","display_name":"Mann Ji","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J I Mann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5091757406","display_name":"D. J. Newton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D J Newton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.4845,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.88929163,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"1","issue":"3","first_page":"143","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9369999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9369999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.03280000016093254,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperinsulinemia","display_name":"hyperinsulinemia","score":0.9940000176429749},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.7319999933242798},{"id":"https://openalex.org/keywords/electrocardiographic-abnormalities","display_name":"electrocardiographic abnormalities","score":0.9629999995231628},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.7739999890327454},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.6399999856948853},{"id":"https://openalex.org/keywords/fasting-insulin","display_name":"fasting insulin","score":0.7799999713897705},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.6679999828338623},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.6959999799728394},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.4129999876022339}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8828703165054321},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8128657341003418},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5970126390457153},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5695162415504456},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.5497834086418152},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.5479649305343628},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5451289415359497},{"id":"https://openalex.org/C50965678","wikidata":"https://www.wikidata.org/wiki/Q2724302","display_name":"Abnormality","level":2,"score":0.5251448154449463},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.4955815076828003},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4288252294063568},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005951","descriptor_name":"Glucose Tolerance Test","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006331","descriptor_name":"Heart Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:6397290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6397290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes research (Edinburgh, Scotland)","raw_type":"Journal Article"},{"id":"mag:2397617233","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6397290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1987444424","https://openalex.org/W1952605013","https://openalex.org/W6967949428","https://openalex.org/W4389444537","https://openalex.org/W1771125310","https://openalex.org/W4409687178","https://openalex.org/W2329998805","https://openalex.org/W2111504901","https://openalex.org/W2017741780","https://openalex.org/W2359372971"],"abstract_inverted_index":{"Twelve-lead":[0],"electrocardiograms":[1],"(ECGs)":[2],"were":[3,27,105,156,213],"recorded":[4,106],"at":[5,111,215],"diagnosis":[6,112],"from":[7,83,87,107,128,135],"247":[8],"initially":[9],"non-insulin-requiring":[10],"diabetics.":[11],"The":[12,25,117],"record":[13,118],"was":[14,119,143,243],"normal":[15,73,120,129,138,208],"in":[16,22,124,132,139,148,218],"208":[17],"(84%)":[18],"patients":[19,79,109],"and":[20,37,39,57,85,98,113,142,161,190,196,231],"abnormal":[21,131,136,144],"39":[23],"(16%).":[24],"latter":[26],"older":[28,157],"(p":[29,53,59,158,171,201],"=":[30,159,172,194,202],"0.002),":[31],"with":[32,72,206,220,225],"higher":[33,51,227],"blood":[34,229],"pressures":[35],"(diastolic":[36],"systolic)":[38],"greater":[40,163,177,214],"cardiothoracic":[41],"ratios":[42],"(all":[43],"p":[44,193,237],"less":[45,54,60,238],"than":[46,55,61,70,204,239],"0.02).":[47],"They":[48,174],"also":[49,175],"had":[50,80,92,162,176],"fasting":[52,165,178,232],"0.01)":[56],"post-glucose":[58,212],"0.04)":[62],"plasma":[63],"insulin":[64,179],"concentrations":[65],"per":[66,181],"body":[67,182],"mass":[68,183],"index":[69,184],"those":[71,205,219],"ECGs.":[74],"Five":[75],"years":[76],"later":[77],"17":[78],"died":[81],"(4":[82],"proven":[84,95],"6":[86],"suspected":[88,101],"cardiac":[89,102,221],"cause),":[90],"5":[91,114,169,216],"sustained":[93],"a":[94,100],"myocardial":[96],"infarct":[97],"3":[99],"event.":[103],"ECGs":[104],"138":[108],"both":[110,122,146,185],"yr":[115,170,217],"later.":[116],"on":[121,145],"occasions":[123,147],"100":[125],"(72%),":[126],"changed":[127],"to":[130,137],"21":[133],"(15%),":[134],"9":[140],"(7%),":[141],"8":[149],"(6%).":[150],"Patients":[151],"who":[152],"developed":[153,200],"ECG":[154],"abnormalities":[155],"0.011),":[160],"mean":[164],"cholesterol":[166],"during":[167],"the":[168,198,226],"0.05).":[173],"levels":[180,211],"before":[186],"(mean":[187],"of":[188],"initial":[189],"1-yr":[191],"values,":[192],"0.02)":[195],"after":[197],"abnormality":[199,222],"0.003)":[203],"persistently":[207],"recordings.":[209],"Insulin":[210],"but,":[223],"as":[224],"diastolic":[228],"pressure":[230],"glucose":[233],"concentration":[234],"then":[235],"(both":[236],"0.05),":[240],"this":[241],"difference":[242],"not":[244],"significant":[245],"initially.":[246],"(ABSTRACT":[247],"TRUNCATED":[248],"AT":[249],"250":[250],"WORDS)":[251]},"counts_by_year":[{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}