{"id":"https://openalex.org/W2397581301","doi":null,"title":"Surveillance-only policy in clinical stage-I non-seminomatous germ-cell tumors of the testis.","display_name":"Surveillance-only policy in clinical stage-I non-seminomatous germ-cell tumors of the testis.","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W2397581301","mag":"2397581301","pmid":"https://pubmed.ncbi.nlm.nih.gov/10846534"},"language":"en","primary_location":{"id":"pmid:10846534","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10846534","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin du cancer","raw_type":"Journal Article"},"parent_works":[],"lineage":["https://openalex.org/W2397581301"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049476362","display_name":"Serdar Tekg\u00fcl","orcid":"https://orcid.org/0000-0002-3708-459X","observed_orcids":["https://orcid.org/0000-0002-3708-459X"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"S Tekg\u00fcl","raw_affiliation_strings":["Hacettepe University Medical School, Department of Urology, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hacettepe University Medical School, Department of Urology, Ankara, Turkey","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043531318","display_name":"Hasan \u00d6zen","orcid":"https://orcid.org/0000-0002-9063-3893","observed_orcids":["https://orcid.org/0000-0002-9063-3893","https://orcid.org/0000-0002-6820-2536"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Ozen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023294910","display_name":"I\u015f\u0131k Hasan \u00d6zg\u00fc","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I Ozg\u00fc","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011253177","display_name":"Ahmet \u015eahin","orcid":"https://orcid.org/0000-0003-1354-988X","observed_orcids":["https://orcid.org/0000-0003-1354-988X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Sahin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102953676","display_name":"A. Ergen","orcid":"https://orcid.org/0000-0003-1710-8205","observed_orcids":["https://orcid.org/0000-0003-1710-8205"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Ergen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103760771","display_name":"D. Remzi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Remzi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"82","issue":"2","first_page":"162","last_page":"166"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11069","display_name":"Testicular diseases and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nonseminomatous-germ-cell-tumors","display_name":"non-seminoma","score":0.9399999976158142},{"id":"https://openalex.org/keywords/testicular-cancer","display_name":"testicular cancer","score":0.8169999718666077},{"id":"https://openalex.org/keywords/stage-i","display_name":"stage I","score":0.7519999742507935},{"id":"https://openalex.org/keywords/surveillance-medicine","display_name":"surveillance (medicine)","score":0.3569999933242798},{"id":"https://openalex.org/keywords/active-surveillance","display_name":"active surveillance","score":0.609000027179718},{"id":"https://openalex.org/keywords/cisplatin-based-chemotherapy","display_name":"cisplatin-based chemotherapy","score":0.7889999747276306},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.871999979019165},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.5640000104904175},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9610000252723694},{"id":"https://openalex.org/keywords/embryonal-carcinoma","display_name":"embryonal carcinoma","score":0.9900000095367432},{"id":"https://openalex.org/keywords/yolk-sac-tumor","display_name":"yolk sac tumor","score":0.8659999966621399},{"id":"https://openalex.org/keywords/orchiectomy","display_name":"orchiectomy","score":0.5260000228881836}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7905020713806152},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6630820035934448},{"id":"https://openalex.org/C2776938808","wikidata":"https://www.wikidata.org/wiki/Q1737977","display_name":"Germ cell tumors","level":3,"score":0.5785958170890808},{"id":"https://openalex.org/C2781447364","wikidata":"https://www.wikidata.org/wiki/Q584992","display_name":"Tumor marker","level":3,"score":0.5683051347732544},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5303972959518433},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.5158359408378601},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5137754082679749},{"id":"https://openalex.org/C2780327976","wikidata":"https://www.wikidata.org/wiki/Q1451877","display_name":"Embryonal carcinoma","level":4,"score":0.4621911644935608},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4615170657634735},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.4318818151950836},{"id":"https://openalex.org/C2776212926","wikidata":"https://www.wikidata.org/wiki/Q324464","display_name":"Testicular cancer","level":3,"score":0.4110143780708313},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.387143075466156},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.34923815727233887},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009919","descriptor_name":"Orchiectomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013736","descriptor_name":"Testicular Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D013736","descriptor_name":"Testicular Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013736","descriptor_name":"Testicular Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018237","descriptor_name":"Germinoma","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018237","descriptor_name":"Germinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018237","descriptor_name":"Germinoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:10846534","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10846534","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin du cancer","raw_type":"Journal Article"},{"id":"mag:2397581301","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10846534","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W115894463","https://openalex.org/W2047697548","https://openalex.org/W2001672955","https://openalex.org/W1954862987","https://openalex.org/W2055393112","https://openalex.org/W2002587697","https://openalex.org/W2108328835","https://openalex.org/W1998375776","https://openalex.org/W2074438172","https://openalex.org/W2402561100"],"abstract_inverted_index":{"With":[0],"the":[1,5,12,59,63,66,73,87,104,114,132,139,162,170,173,201,218],"advanced":[2],"imaging":[3],"techniques,":[4],"sensitive":[6],"assays":[7],"for":[8,134],"tumor":[9,71,203],"markers":[10],"and":[11,65,68,131,148,193,214,223],"curability":[13],"of":[14,56,62,96,103,111,141,145,161,200],"small-volume":[15],"metastatic":[16],"disease":[17,112],"with":[18,48,82,109,177,197],"cis-platinum-based":[19,83],"chemotherapy,":[20],"surveillance":[21,45],"has":[22],"gained":[23],"popularity":[24],"in":[25,43,93,113,168,188],"clinical":[26],"stage-I":[27],"non-seminomatous":[28],"germ-cell":[29],"tumors.":[30],"This":[31],"study":[32],"reports":[33],"our":[34],"experience":[35],"on":[36,58],"58":[37,88],"patients":[38,79,106,176,219],"who":[39],"have":[40],"been":[41],"included":[42],"a":[44,94,185,212],"protocol.":[46],"Patients":[47],"normal":[49],"tumor-marker":[50,180,189],"levels":[51,190,199],"following":[52],"surgery,":[53],"no":[54,69],"evidence":[55,110],"metastases":[57],"CT":[60],"scans":[61],"abdomen":[64],"chest":[67],"residual":[70],"at":[72],"surgical":[74],"margin":[75],"were":[76,80,126,151,165],"followed.":[77],"Relapsing":[78],"treated":[81],"combination":[84],"chemotherapy.":[85,123],"Of":[86,172],"patients,":[89],"17":[90],"relapsed":[91,196],"(29.3%)":[92],"period":[95,116],"2-18":[97],"months":[98,118],"(median":[99,119],"5":[100],"months).":[101],"None":[102],"relapsing":[105,175],"later":[107],"presented":[108],"follow-up":[115],"14-79":[117],"39":[120],"months)":[121],"after":[122],"Prognostic":[124],"factors":[125,164],"evaluated":[127,152],"by":[128,153],"univariate":[129],"analysis":[130,157],"data":[133],"risk":[135,163],"factors,":[136],"such":[137],"as":[138],"presence":[140],"embryonal":[142],"carcinoma,":[143],"absence":[144],"yolk-sac":[146],"elements":[147],"scrotal":[149],"violation,":[150],"multivariate":[154],"analysis.":[155],"Statistical":[156],"showed":[158],"that":[159],"none":[160],"significantly":[166],"different":[167],"predicting":[169],"relapse.":[171],"6":[174],"preorchiectomy":[178],"elevated":[179,198],"levels,":[181],"4":[182],"had":[183],"shown":[184],"slower":[186],"decline":[187],"than":[191],"expected":[192],"they":[194],"all":[195],"same":[202],"markers.":[204],"A":[205],"surveillance-only":[206],"policy":[207],"actually":[208],"seems":[209],"to":[210],"be":[211],"safe":[213],"logical":[215],"approach":[216],"if":[217],"are":[220],"properly":[221],"selected":[222],"cooperate":[224],"fully.":[225]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-15T12:55:33.944570","created_date":"2016-06-24T00:00:00"}