{"id":"https://openalex.org/W2397574556","doi":null,"title":"Is Fasting Leptin Associated With Insulin Resistance Among Nondiabetic I n d i v i d u a l s","display_name":"Is Fasting Leptin Associated With Insulin Resistance Among Nondiabetic I n d i v i d u a l s","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W2397574556","mag":"2397574556"},"language":"en","primary_location":{"id":"mag:2397574556","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Maximilian_De_Courten/publication/12910191_Is_fasting_leptin_associated_with_insulin_resistance_among_nondiabetic_individuals_The_Miami_Community_Health_Study/links/0fcfd50d0e80953222000000.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109906757","display_name":"Richard P. Donahue","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard P. Donahue","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087659816","display_name":"Ronald J. Prineas","orcid":"https://orcid.org/0000-0001-7494-0634","observed_orcids":["https://orcid.org/0000-0001-7494-0634"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ronald J. Prineas","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7494-0634","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000239787","display_name":"Rosemary A.Decarlo Donahue","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rosemary Decarlo Donahue","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019887736","display_name":"Paul Zimmet","orcid":"https://orcid.org/0000-0003-0627-0776","observed_orcids":["https://orcid.org/0000-0003-0627-0776"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul Zimmet","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0627-0776","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111449805","display_name":"Judy A. Bean","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Judy A. Bean","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035782276","display_name":"Maximilian de Courten","orcid":"https://orcid.org/0000-0001-9997-9359","observed_orcids":["https://orcid.org/0000-0001-9997-9359"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maximilian de Courten","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-9997-9359","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108548281","display_name":"Gregory Collier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gregory Collier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011389314","display_name":"Ronald B Goldberg","orcid":"https://orcid.org/0000-0003-0924-1110","observed_orcids":["https://orcid.org/0000-0003-0924-1110"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ronald Goldberg","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0924-1110","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023214700","display_name":"Jay S. Skyler","orcid":"https://orcid.org/0000-0003-1136-8110","observed_orcids":["https://orcid.org/0000-0003-1136-8110"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jay S. Skyler","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1136-8110","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5005740279","display_name":"Neil Schneiderman","orcid":"https://orcid.org/0000-0002-7982-068X","observed_orcids":["https://orcid.org/0000-0002-7982-068X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neil Schneiderman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28624623,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6172000169754028,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6172000169754028,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.3610999882221222,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.011500000022351742,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.9779999852180481},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.996999979019165},{"id":"https://openalex.org/keywords/insulin-stimulated-glucose-uptake","display_name":"insulin-stimulated glucose uptake","score":0.8529999852180481},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.7110000252723694},{"id":"https://openalex.org/keywords/body-fat-percentage","display_name":"body fat percentage","score":0.8140000104904175},{"id":"https://openalex.org/keywords/hyperinsulinemia","display_name":"hyperinsulinemia","score":0.9210000038146973},{"id":"https://openalex.org/keywords/nondiabetic-adults","display_name":"non-diabetic adults","score":0.8199999928474426},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.8555077314376831},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.844075083732605},{"id":"https://openalex.org/C2780988686","wikidata":"https://www.wikidata.org/wiki/Q14375936","display_name":"Hyperinsulinemia","level":4,"score":0.8086602091789246},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.8052916526794434},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8041447401046753},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.6871680617332458},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.657206118106842},{"id":"https://openalex.org/C2778808658","wikidata":"https://www.wikidata.org/wiki/Q2975183","display_name":"Glucose clamp technique","level":5,"score":0.4326038062572479},{"id":"https://openalex.org/C2780352109","wikidata":"https://www.wikidata.org/wiki/Q728309","display_name":"Pancreatic hormone","level":4,"score":0.39189356565475464},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.3878556191921234}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2397574556","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Maximilian_De_Courten/publication/12910191_Is_fasting_leptin_associated_with_insulin_resistance_among_nondiabetic_individuals_The_Miami_Community_Health_Study/links/0fcfd50d0e80953222000000.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9907000064849854,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W2103240729","https://openalex.org/W2149325380","https://openalex.org/W2179880609"],"related_works":["https://openalex.org/W2000007586","https://openalex.org/W2011865662","https://openalex.org/W2323424747","https://openalex.org/W1974486640","https://openalex.org/W2081765311","https://openalex.org/W1999338955","https://openalex.org/W2061772512","https://openalex.org/W2380665967","https://openalex.org/W2347630242","https://openalex.org/W2124275445"],"abstract_inverted_index":{"dent":[0],"of":[1,4,20,67,82,93,164,211,244],"the":[2,15,18,58,138,143,226,232,242],"effects":[3],"hyperinsulinemia":[5],"and":[6,24,31,53,79,119,136,157,213],"adiposity":[7],"is":[8],"an":[9],"important":[10],"unanswered":[11],"question.":[12],"We":[13],"examined":[14],"relationship":[16],"between":[17],"rate":[19,92],"insulin-mediated":[21,94],"glucose":[22,95],"uptake":[23,96],"serum":[25,76],"leptin":[26,77,108,159,197],"concentrations":[27,109],"among":[28,47],"nondiabetic":[29,209],"men":[30,52,112,212],"women.":[32,214],"RESEARCH":[33],"DESIGN":[34],"AND":[35],"METHODS":[36],"\u2014":[37,90,180],"A":[38],"cross-sectional":[39],"analysis":[40],"was":[41,104,128,198],"perf":[42],"o":[43,191,238],"rm":[44],"e":[45,152,187,220],"d":[46],"49":[48],"young":[49],"to":[50,132,137,224],"middle-aged":[51],"women":[54,120],"who":[55],"participated":[56],"in":[57,98,110,207],"Miami":[59],"Community":[60],"Health":[61],"Study.":[62],"All":[63],"participants":[64],"had":[65],"measures":[66,81],"insulin":[68,73,140,202],"resistance":[69,228],"(euglycemic-hyperinsulinemic":[70],"clamp),":[71],"postchallenge":[72],"levels,":[74,78],"fasting":[75],"several":[80],"adiposity.":[83],"R":[84],"E":[85],"S":[86,89,175,179],"U":[87,174],"LT":[88],"The":[91],"(M":[97],"milligrams":[99],"per":[100,102],"kilogram":[101],"minute)":[103],"significantly":[105,199],"associated":[106,200],"with":[107,201],"both":[111],"(r":[113,121],"=":[114,122,167],"20.83;":[115],"P":[116,124],",":[117,125],"0.001)":[118],"20.59;":[123],"0.001).":[126],"M":[127,165],"also":[129],"inversely":[130],"related":[131],"percent":[133],"body":[134,155],"fat":[135],"2-h":[139],"area":[141],"under":[142],"curve":[144],"(AUC).":[145],"After":[146],"covariate":[147],"adjustment":[148],"for":[149],"sex,":[150],"perc":[151],"n":[153,192],"t":[154,189,237],"fat,":[156],"AUC,":[158],"remained":[160],"a":[161,193,218,236],"significant":[162],"correlate":[163],"(P":[166],"0.04).":[168],"C":[169,172,181],"O":[170,177],"N":[171,178],"L":[173],"I":[176],"ro":[182],"s":[183,184,186,204],"-":[185],"c":[188],"i":[190,205],"l":[194,195],"y,":[196],"re":[203],"stance":[206],"this":[208],"sample":[210],"There":[215],"may":[216],"be":[217],"diff":[219],"rent":[221],"physiological":[222],"mechanism":[223],"explain":[225],"leptin/insulin":[227],"association":[229],"apart":[230],"from":[231],"insulin/adiposity":[233],"link.":[234],"Confirm":[235],"ry":[239],"evidence":[240],"awaits":[241],"results":[243],"clinical":[245],"trials.":[246]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}