{"id":"https://openalex.org/W2397568810","doi":null,"title":"A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.","display_name":"A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.","publication_year":1989,"publication_date":"1989-07-01","ids":{"openalex":"https://openalex.org/W2397568810","mag":"2397568810","pmid":"https://pubmed.ncbi.nlm.nih.gov/2666912"},"language":"en","primary_location":{"id":"pmid:2666912","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2666912","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015012444","display_name":"Elise Brownell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E Brownell","raw_affiliation_strings":["Laboratory of Molecular Virology and Carcinogenesis, NCI-Frederick Cancer Research Facility, Maryland 21701"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Virology and Carcinogenesis, NCI-Frederick Cancer Research Facility, Maryland 21701","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031922621","display_name":"Nanette Mittereder","orcid":"https://orcid.org/0000-0001-5533-6247","observed_orcids":["https://orcid.org/0000-0001-5533-6247"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Mittereder","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5046288456","display_name":"Rice Nr","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N R Rice","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.6305,"has_fulltext":false,"cited_by_count":164,"citation_normalized_percentile":{"value":0.96541763,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":"7","first_page":"935","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9599999785423279,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9599999785423279,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.019300000742077827,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alu-elements","display_name":"Alu elements","score":0.7450000047683716},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7599999904632568},{"id":"https://openalex.org/keywords/novel-exons","display_name":"novel exons","score":0.4749999940395355},{"id":"https://openalex.org/keywords/v-rel","display_name":"v-Rel","score":0.7039999961853027},{"id":"https://openalex.org/keywords/daudi-cells","display_name":"Daudi cells","score":0.7860000133514404},{"id":"https://openalex.org/keywords/human-mrna","display_name":"human mRNA","score":0.32499998807907104},{"id":"https://openalex.org/keywords/open-reading-frames","display_name":"open reading frames","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8709613084793091},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.8497973084449768},{"id":"https://openalex.org/C48931128","wikidata":"https://www.wikidata.org/wiki/Q412199","display_name":"Alu element","level":5,"score":0.8463180065155029},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6134753823280334},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.6055819988250732},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5963327884674072},{"id":"https://openalex.org/C81089528","wikidata":"https://www.wikidata.org/wiki/Q5134986","display_name":"clone (Java method)","level":3,"score":0.5903173089027405},{"id":"https://openalex.org/C187882448","wikidata":"https://www.wikidata.org/wiki/Q283478","display_name":"Complementary DNA","level":3,"score":0.5791072845458984},{"id":"https://openalex.org/C156446351","wikidata":"https://www.wikidata.org/wiki/Q7682435","display_name":"Tandem exon duplication","level":4,"score":0.5597650408744812},{"id":"https://openalex.org/C39917842","wikidata":"https://www.wikidata.org/wiki/Q1384125","display_name":"Exon trapping","level":5,"score":0.5429103970527649},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.3827824890613556},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3271178901195526},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.23836299777030945},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.12811166048049927}],"mesh":[{"descriptor_ui":"D000090063","descriptor_name":"Proto-Oncogene Mas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011519","descriptor_name":"Proto-Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012091","descriptor_name":"Repetitive Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014176","descriptor_name":"Protein Biosynthesis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020569","descriptor_name":"Proto-Oncogene Proteins c-rel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:2666912","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2666912","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncogene","raw_type":"Journal Article"},{"id":"mag:2397568810","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2666912","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G187081405","display_name":"BASIC RESEARCH--CANCER INSTITUTE FREDERICK","funder_award_id":"n01co074101-034","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1984502430","https://openalex.org/W2050434777","https://openalex.org/W1972257798","https://openalex.org/W2402155730","https://openalex.org/W2044136480","https://openalex.org/W2167426362","https://openalex.org/W2417937308","https://openalex.org/W2127932826","https://openalex.org/W2290540170","https://openalex.org/W2033837701"],"abstract_inverted_index":{"Two":[0],"rel-containing":[1],"cDNA":[2],"clones":[3],"were":[4],"isolated":[5],"from":[6,10,35],"a":[7,84,96,133,151,167],"library":[8],"derived":[9],"the":[11,28,92,115,122,154,158,171],"Daudi":[12],"human":[13,88,138],"cell":[14],"line,":[15],"which":[16,33],"is":[17,146],"known":[18],"to":[19,26],"express":[20],"c-rel":[21,30,89,159],"mRNA.":[22],"Clone":[23,50,67],"#1":[24,51],"appeared":[25],"contain":[27,78],"entire":[29],"coding":[31,129],"sequence,":[32],"differs":[34],"v-rel":[36,62],"in":[37,61,64,114,137,170],"having":[38],"three":[39],"additional":[40,45],"N-terminal":[41],"residues":[42],"and":[43,75,109],"111":[44],"C-terminal":[46],"residues.":[47],"In":[48],"addition,":[49],"had":[52],"an":[53,99],"internal":[54],"32":[55],"amino":[56],"acid":[57],"exon":[58,94,173],"not":[59,77],"found":[60],"or":[63],"turkey":[65],"c-rel.":[66],"#2":[68],"was":[69,95],"truncated":[70],"at":[71,153],"its":[72],"5'":[73],"end":[74],"did":[76,174],"this":[79],"new":[80,93],"exon.":[81],"Analysis":[82],"of":[83,87,98,105,110,124,157],"genomic":[85],"clone":[86],"revealed":[90],"that":[91,121],"portion":[97],"inverted":[100,116],"Alu":[101,118,125,172],"repeat.":[102],"The":[103],"occurrence":[104],"potential":[106,128],"splice":[107],"sites":[108],"open":[111],"reading":[112],"frames":[113],"consensus":[117],"sequence":[119],"suggests":[120],"incorporation":[123],"fragments":[126],"as":[127],"exons":[130],"could":[131],"be":[132,144],"relatively":[134],"common":[135],"event":[136],"mRNAs.":[139],"Whether":[140],"such":[141],"messages":[142],"can":[143],"translated":[145],"unknown:":[147],"antiserum":[148,164],"raised":[149,165],"against":[150,166],"peptide":[152,168],"predicted":[155],"C-terminus":[156],"protein":[160],"precipitated":[161],"p82hc-rel,":[162],"but":[163],"located":[169],"not.":[175]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}