{"id":"https://openalex.org/W2397468902","doi":null,"title":"The effect of cigarette smoking on vitamin C and vitamin E levels of gingival crevicular fluid.","display_name":"The effect of cigarette smoking on vitamin C and vitamin E levels of gingival crevicular fluid.","publication_year":1999,"publication_date":"1999-03-01","ids":{"openalex":"https://openalex.org/W2397468902","mag":"2397468902","pmid":"https://pubmed.ncbi.nlm.nih.gov/11148984"},"language":"en","primary_location":{"id":"pmid:11148984","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11148984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bollettino della Societa italiana di biologia sperimentale","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/34b7c1d8cc67402ba72a0b5810f59a84","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059636774","display_name":"Marco Seri","orcid":"https://orcid.org/0000-0003-2425-2176","observed_orcids":["https://orcid.org/0000-0003-2425-2176"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M Seri","raw_affiliation_strings":["Institute of Restorative Dentistry, University of Rome La Sapienza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Restorative Dentistry, University of Rome La Sapienza","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":null,"display_name":"A D'Alessandro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A D'Alessandro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5110208654","display_name":"S Seri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Seri","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.36330163,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"75","issue":"3-4","first_page":"21","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0803999975323677,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cigarette-smoking","display_name":"cigarette smoking","score":0.996999979019165},{"id":"https://openalex.org/keywords/gingival-crevicular-fluid","display_name":"gingival crevicular fluid","score":0.921999990940094},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.9700000286102295},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.8830000162124634},{"id":"https://openalex.org/keywords/tocopherols","display_name":"tocopherols","score":0.996999979019165},{"id":"https://openalex.org/keywords/vitamin-a","display_name":"vitamin A","score":0.9879999756813049},{"id":"https://openalex.org/keywords/tobacco-smoke","display_name":"tobacco smoke","score":0.7360000014305115},{"id":"https://openalex.org/keywords/antioxidant-status","display_name":"antioxidant status","score":0.46700000762939453},{"id":"https://openalex.org/keywords/vasoconstriction","display_name":"vasoconstriction","score":0.8389999866485596}],"concepts":[{"id":"https://openalex.org/C2986274086","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Ascorbic acid","level":2,"score":0.7734647989273071},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7514350414276123},{"id":"https://openalex.org/C2781449162","wikidata":"https://www.wikidata.org/wiki/Q910277","display_name":"Tocopherol","level":4,"score":0.6553722023963928},{"id":"https://openalex.org/C2993351451","wikidata":"https://www.wikidata.org/wiki/Q2386268","display_name":"Cigarette smoke","level":2,"score":0.6184645295143127},{"id":"https://openalex.org/C2780022331","wikidata":"https://www.wikidata.org/wiki/Q199678","display_name":"Vitamin C","level":2,"score":0.5808847546577454},{"id":"https://openalex.org/C2777551382","wikidata":"https://www.wikidata.org/wiki/Q141180","display_name":"Vitamin E","level":3,"score":0.5751872658729553},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.5400640964508057},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.5050256848335266},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5002479553222656},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.46567222476005554},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.443163126707077},{"id":"https://openalex.org/C3019085024","wikidata":"https://www.wikidata.org/wiki/Q7212330","display_name":"Cigarette smoking","level":2,"score":0.42165833711624146},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.38474011421203613},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16398340463638306},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.1420038342475891},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08086657524108887},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.07776442170143127}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001205","descriptor_name":"Ascorbic Acid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005881","descriptor_name":"Gingiva","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D005881","descriptor_name":"Gingiva","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005883","descriptor_name":"Gingival Crevicular Fluid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005883","descriptor_name":"Gingival Crevicular Fluid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D014810","descriptor_name":"Vitamin E","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:11148984","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11148984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bollettino della Societa italiana di biologia sperimentale","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:34b7c1d8cc67402ba72a0b5810f59a84","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/34b7c1d8cc67402ba72a0b5810f59a84","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biological Research, Vol 75, Iss 3-4","raw_type":"article"},{"id":"mag:2397468902","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11148984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:34b7c1d8cc67402ba72a0b5810f59a84","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/34b7c1d8cc67402ba72a0b5810f59a84","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Biological Research, Vol 75, Iss 3-4","raw_type":"article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2215877406","https://openalex.org/W2150591887","https://openalex.org/W336559474","https://openalex.org/W6968329085","https://openalex.org/W1970812604","https://openalex.org/W143777263","https://openalex.org/W2077705104","https://openalex.org/W2007639831","https://openalex.org/W2786727059","https://openalex.org/W2054515886"],"abstract_inverted_index":{"The":[0,27,148],"purpose":[1],"of":[2,19,76,91,104,121,136,170,176,188],"this":[3,66],"study":[4],"was":[5,29],"to":[6,36,46,113,126,161],"assay":[7],"the":[8,32,39,144,168,189],"ascorbic":[9],"acid":[10,100],"and":[11,21,38,60,80,88,97,101,179,185],"tocopherol":[12,102,134],"levels":[13,120,151],"in":[14,65,72,124,128,157,159],"gingival":[15,172],"crevicular":[16],"fluid":[17],"(GCF)":[18],"smokers":[20,137,158],"nonsmokers":[22,59,127],"with":[23],"clinically":[24],"healthy":[25],"gingiva.":[26],"comparison":[28,125,160],"determined":[30,107],"between":[31,143],"area":[33,75],"physically":[34],"exposed":[35],"smoke":[37,165],"controlateral":[40,81],"area.":[41,82],"All":[42],"tested":[43],"areas":[44],"required":[45],"be":[47,167],"free":[48],"from":[49],"periodontal":[50],"diseases":[51],"at":[52,86],"a":[53,171,183,186],"screening":[54],"examination.":[55],"41":[56],"students":[57],"(16":[58],"25":[61],"smokers)":[62],"were":[63,70,85,106,111],"enrolled":[64],"study.":[67],"GCF":[68,105,133],"samples":[69],"collected":[71],"two":[73,145],"regions:":[74],"habitual":[77],"cigarette":[78],"placement":[79],"Areas":[83],"sampled":[84],"midbuccal":[87],"midlingual":[89],"sites":[90],"all":[92,129],"teeth":[93],"3,":[94],"5,":[95],"6,":[96],"7.":[98],"Ascorbic":[99],"values":[103],"by":[108,174],"HPLC.":[109],"Smokers":[110],"found":[112],"have":[114],"significant":[115,141],"(p":[116],"<":[117],"0.05)":[118],"lower":[119],"vitamin":[122,149,177],"C":[123,178],"regions":[130,146],"tested.":[131],"Mean":[132],"concentration":[135],"did":[138],"not":[139],"reveal":[140],"differences":[142],"examined.":[147],"A":[150,180],"revealed":[152],"an":[153],"unsignificant":[154],"low":[155],"value":[156],"control":[162],"subjects.":[163],"Tobacco":[164],"can":[166],"cause":[169],"damage":[173],"decrease":[175],"operating":[181],"through":[182],"vasoconstriction":[184],"reduction":[187],"antioxidant":[190],"properties.":[191]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}