{"id":"https://openalex.org/W2397381850","doi":null,"title":"EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF JOINTS KARE A POLYHERBAL FORMULATION - EXPERIMENTAL STUDY","display_name":"EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF JOINTS KARE A POLYHERBAL FORMULATION - EXPERIMENTAL STUDY","publication_year":2015,"publication_date":"2015-12-15","ids":{"openalex":"https://openalex.org/W2397381850","mag":"2397381850"},"language":"en","primary_location":{"id":"pmh:oai:ijapr.in:article/189","doi":null,"is_oa":true,"landing_page_url":"https://ijapr.in/index.php/ijapr/article/view/189","pdf_url":"https://ijapr.in/index.php/ijapr/article/download/189/175","source":{"id":"https://openalex.org/S2764913460","display_name":"International Journal of Ayurveda and Pharma Research","issn_l":"2322-0902","issn":["2322-0902","2322-0910"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4366725212","host_organization_name":"Mahadev Publications","host_organization_lineage":["https://openalex.org/P4366725212"],"host_organization_lineage_names":["Mahadev Publications"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2322-0902","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://ijapr.in/index.php/ijapr/article/download/189/175","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110739308","display_name":"Amnish Verma","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amnish Verma","raw_affiliation_strings":["Advisor (R & D), Jammu Institute of Ayurveda and Research Pharmacy, Jammu, J & K, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advisor (R & D), Jammu Institute of Ayurveda and Research Pharmacy, Jammu, J & K, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101077437","display_name":"Roop Lal Sharma","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Roop Lal Sharma","raw_affiliation_strings":["Chairman, Jammu Institute of Ayurveda and Research Pharmacy, Jammu, J & K, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chairman, Jammu Institute of Ayurveda and Research Pharmacy, Jammu, J & K, India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2","issue":"8","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.39010000228881836,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.39010000228881836,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants","score":0.2782999873161316,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13335","display_name":"Pharmacological Effects of Medicinal Plants","score":0.13230000436306,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polyherbal-formulation","display_name":"polyherbal formulation","score":0.9620000123977661},{"id":"https://openalex.org/keywords/ayurveda","display_name":"Ayurveda","score":0.7039999961853027},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":1.0},{"id":"https://openalex.org/keywords/carrageenan-induced-paw-edema","display_name":"carrageenan-induced paw edema","score":0.9559999704360962},{"id":"https://openalex.org/keywords/ibuprofen-comparison","display_name":"ibuprofen comparison","score":0.8029999732971191},{"id":"https://openalex.org/keywords/edema-inhibition","display_name":"edema inhibition","score":0.7009999752044678},{"id":"https://openalex.org/keywords/joint-pain","display_name":"joint pain","score":0.3700000047683716}],"concepts":[{"id":"https://openalex.org/C2781227287","wikidata":"https://www.wikidata.org/wiki/Q421991","display_name":"Carrageenan","level":2,"score":0.729407787322998},{"id":"https://openalex.org/C2779944601","wikidata":"https://www.wikidata.org/wiki/Q186969","display_name":"Ibuprofen","level":2,"score":0.6914145350456238},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.6350294947624207},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5946848392486572},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.4141431748867035},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.31428688764572144},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2424304187297821}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ijapr.in:article/189","doi":null,"is_oa":true,"landing_page_url":"https://ijapr.in/index.php/ijapr/article/view/189","pdf_url":"https://ijapr.in/index.php/ijapr/article/download/189/175","source":{"id":"https://openalex.org/S2764913460","display_name":"International Journal of Ayurveda and Pharma Research","issn_l":"2322-0902","issn":["2322-0902","2322-0910"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4366725212","host_organization_name":"Mahadev Publications","host_organization_lineage":["https://openalex.org/P4366725212"],"host_organization_lineage_names":["Mahadev Publications"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2322-0902","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2397381850","doi":null,"is_oa":true,"landing_page_url":"http://ijapr.in/index.php/ijapr/article/view/189/0","pdf_url":null,"source":{"id":"https://openalex.org/S2764913460","display_name":"International Journal of Ayurveda and Pharma Research","issn_l":"2322-0902","issn":["2322-0902","2322-0910"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4366725212","host_organization_name":"Mahadev Publications","host_organization_lineage":["https://openalex.org/P4366725212"],"host_organization_lineage_names":["Mahadev Publications"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Ayurveda and Pharma Research","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ijapr.in:article/189","doi":null,"is_oa":true,"landing_page_url":"https://ijapr.in/index.php/ijapr/article/view/189","pdf_url":"https://ijapr.in/index.php/ijapr/article/download/189/175","source":{"id":"https://openalex.org/S2764913460","display_name":"International Journal of Ayurveda and Pharma Research","issn_l":"2322-0902","issn":["2322-0902","2322-0910"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4366725212","host_organization_name":"Mahadev Publications","host_organization_lineage":["https://openalex.org/P4366725212"],"host_organization_lineage_names":["Mahadev Publications"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2322-0902","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2397381850.pdf","grobid_xml":"https://content.openalex.org/works/W2397381850.grobid-xml"},"referenced_works_count":2,"referenced_works":["https://openalex.org/W2048722122","https://openalex.org/W2320758398"],"related_works":["https://openalex.org/W2185726791","https://openalex.org/W2346717021","https://openalex.org/W7221280659","https://openalex.org/W2084467705","https://openalex.org/W6967889948","https://openalex.org/W3081772452","https://openalex.org/W2971452164","https://openalex.org/W4389737514","https://openalex.org/W7083634948","https://openalex.org/W2593256709"],"abstract_inverted_index":{"The":[0,56,144,164,233],"Anti-inflammatory":[1],"activity":[2,235,295],"of":[3,18,30,40,67,73,78,114,123,127,134,162,169,204,213,216,218,236,292,296],"JOINTS":[4],"KARE,":[5],"a":[6],"poly":[7],"herbal":[8],"ayurvedic":[9],"formulation":[10],"developed":[11],"and":[12,20,51,84,194,228,244,247,254,302],"studied":[13],"in":[14,62,64,157,166,192,310],"the":[15,24,33,65,71,76,119,129,159,182,201,205,211,248,272,288,298],"Jammu":[16],"Institute":[17,29],"Ayurveda":[19],"Research":[21],"Pharmacy":[22],"with":[23,70,89,174],"technical":[25],"assistance":[26],"from":[27],"Indian":[28],"Integrative":[31],"Medicine,":[32],"study":[34,207],"was":[35,146,172,264],"performed":[36],"on":[37,210,287],"albino":[38,46],"rats":[39,47,63,77,137,217],"carrageenan":[41,115,231],"induced":[42],"model.":[43],"20":[44,136],"healthy":[45],"were":[48,86,138,189,240],"selected":[49],"randomly":[50],"divided":[52],"into":[53,118],"five":[54,130,160,220],"groups.":[55,131],"inflammatory":[57],"reaction":[58],"is":[59,275,307],"readily":[60],"produced":[61],"form":[66],"paw":[68,126,167,215],"oedema":[69,198,212,262],"help":[72],"irritants.":[74],"Here":[75],"treated":[79,183],"Group":[80,170,175,184],"II,":[81,176,185],"III,":[82,177,186],"IV":[83,178],"V":[85,188],"administered":[87],"orally":[88],"Ibuprofen":[90],"solution,":[91],"Joints":[92,97,102,278],"Kare":[93,98,103,279],"125mg/Kg":[94],"Body":[95,100,105],"wt,":[96,101,106],"250mg/Kg":[99],"500mg/Kg":[104],"respectively":[107],"one":[108],"hour":[109],"before":[110],"injecting":[111,142],"1%w/v":[112],"suspension":[113],"(0.1":[116],"ml)":[117],"sub":[120],"plantar":[121],"region":[122],"left":[124],"hind":[125,214],"all":[128,135,158,219,237],"Paw":[132],"volume":[133,145,168],"measured":[139,148,222],"soon":[140],"after":[141,149,223,230,266],"carrageenan.":[143],"again":[147],"1,":[150],"2,":[151],"3,":[152],"4":[153],"&":[154,179,268],"24":[155],"hrs":[156],"groups":[161,221],"rats.":[163],"change":[165],"I":[171],"compared":[173,191],"V.":[180],"Also":[181],"IV,":[187],"also":[190],"between":[193],"expressed":[195],"as":[196],"percentage":[197,261],"inhibition":[199],"by":[200],"drug.":[202],"Results":[203],"present":[206],"are":[208,250,255],"based":[209],"1hr,":[224],"2hrs,":[225],"3hrs,":[226],"4hrs":[227],"24hrs":[229],"injection.":[232],"maximum":[234],"trial":[238],"Groups":[239],"observed":[241],"during":[242],"first":[243],"second":[245],"hr.":[246],"results":[249],"significant":[251],"(P":[252],"<0.005)":[253],"comparable":[256],"to":[257],"standard":[258],"Ibuprofen.":[259],"Highest":[260],"Inhibition":[263],"seen":[265,309],"1":[267],"2":[269],"hrs.":[270],"Summarizing":[271],"above":[273],"it":[274],"concluded":[276],"that":[277],"has":[280],"showed":[281],"its":[282,293],"extreme":[283],"utility":[284],"or":[285],"significance":[286],"inflammation":[289],"probably":[290],"because":[291],"excellent":[294],"inhibiting":[297],"both":[299],"early":[300],"released":[301,304],"late":[303],"mediators":[305],"which":[306],"rarely":[308],"any":[311],"anti-inflammatory":[312],"formulation.":[313]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}