{"id":"https://openalex.org/W2397278340","doi":null,"title":"[Diagnostic efficiency of laboratory tests determining the functional status of the endothelium in patients with chronic diffuse liver diseases].","display_name":"[Diagnostic efficiency of laboratory tests determining the functional status of the endothelium in patients with chronic diffuse liver diseases].","publication_year":2009,"publication_date":"2009-10-01","ids":{"openalex":"https://openalex.org/W2397278340","mag":"2397278340","pmid":"https://pubmed.ncbi.nlm.nih.gov/20000110"},"language":"ru","primary_location":{"id":"pmid:20000110","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20000110","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Klinicheskaia laboratornaia diagnostika","raw_type":"English Abstract"},"parent_works":[],"lineage":["https://openalex.org/W2397278340"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015598437","display_name":"\u0410. \u041f. \u0429\u0435\u043a\u043e\u0442\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0003-0298-2928","observed_orcids":["https://orcid.org/0000-0003-0298-2928"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A P Shchekotova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108716558","display_name":"\u0429\u0435\u043a\u043e\u0442\u043e\u0432 \u0412\u043b\u0430\u0434\u0438\u043c\u0438\u0440 \u0412\u0430\u043b\u0435\u0440\u044c\u0435\u0432\u0438\u0447","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V V Shchekotov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042142884","display_name":"Irina A. Bulatova","orcid":"https://orcid.org/0000-0002-7802-4796","observed_orcids":["https://orcid.org/0000-0002-7802-4796","https://orcid.org/0009-0002-7809-0918"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"I A Bulatova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5015628443","display_name":"Abraham Roitman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A P Ro\u012dtman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":"10","first_page":"24","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9154999852180481,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9154999852180481,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.03750000149011612,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.01080000028014183,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9300000071525574},{"id":"https://openalex.org/keywords/chronic-diffuse-liver-diseases","display_name":"chronic diffuse liver diseases","score":0.7570000290870667},{"id":"https://openalex.org/keywords/endothelial-damage-markers","display_name":"endothelial damage markers","score":0.8859999775886536},{"id":"https://openalex.org/keywords/endothelial-denudation","display_name":"endothelial denudation","score":0.6869999766349792},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/von-willebrand-factor","display_name":"von Willebrand factor","score":1.0},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9929999709129333},{"id":"https://openalex.org/keywords/endothelin-1","display_name":"endothelin-1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.32199999690055847}],"concepts":[{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.7627586126327515},{"id":"https://openalex.org/C2779394231","wikidata":"https://www.wikidata.org/wiki/Q412310","display_name":"Von Willebrand factor","level":3,"score":0.7258908152580261},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.6335922479629517},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5816614031791687},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.5411137938499451},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49701669812202454},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.447469025850296},{"id":"https://openalex.org/C3018561737","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver damage","level":2,"score":0.43109598755836487},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.42518168687820435},{"id":"https://openalex.org/C149601957","wikidata":"https://www.wikidata.org/wiki/Q390566","display_name":"Endothelin 1","level":3,"score":0.42107680439949036},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.09357011318206787},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004730","descriptor_name":"Endothelium, Vascular","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000098","qualifier_name":"blood supply","is_major_topic":false},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008111","descriptor_name":"Liver Function Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014841","descriptor_name":"von Willebrand Factor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D019332","descriptor_name":"Endothelin-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D042461","descriptor_name":"Vascular Endothelial Growth Factor A","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:20000110","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20000110","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Klinicheskaia laboratornaia diagnostika","raw_type":"English Abstract"},{"id":"mag:2397278340","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20000110","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2315563194","https://openalex.org/W4410769784","https://openalex.org/W2420571555","https://openalex.org/W196162680","https://openalex.org/W1848573190","https://openalex.org/W3019786373","https://openalex.org/W2978429735","https://openalex.org/W6922388501","https://openalex.org/W2561070693"],"abstract_inverted_index":{"The":[0,60],"patients":[1],"with":[2],"chronic":[3],"diffuse":[4],"liver":[5],"diseases":[6],"were":[7],"found":[8],"to":[9,43],"have":[10,44],"signs":[11,45],"of":[12,23,28,36,46,62,67,74,81],"endothelial":[13,30,47,68,75],"damage,":[14],"which":[15],"manifests":[16],"itself":[17],"as":[18,49],"increases":[19],"in":[20,40,58,64,71],"the":[21,26,34,65,72,79],"count":[22],"desquamated":[24],"endotheliocytes,":[25],"level":[27],"vascular":[29],"growth":[31],"factor,":[32],"and":[33,42,54,70],"concentration":[35],"von":[37],"Willebrand":[38],"factor":[39],"plasma":[41],"dysfunction":[48,69],"reduced":[50],"nitric":[51],"oxide":[52],"levels":[53],"elevated":[55],"endothelin-1":[56],"concentrations":[57],"plasma.":[59],"magnitude":[61],"changes":[63],"indicators":[66],"markers":[73],"damage":[76],"depends":[77],"on":[78],"severity":[80],"hepatic":[82],"damage.":[83]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}