{"id":"https://openalex.org/W2397039719","doi":"https://doi.org/10.3727/096368915x688263","title":"Retinal Angiogenesis Effects of TGF-\u03b21 and Paracrine Factors Secreted from Human Placental Stem Cells in Response to a Pathological Environment","display_name":"Retinal Angiogenesis Effects of TGF-\u03b21 and Paracrine Factors Secreted from Human Placental Stem Cells in Response to a Pathological Environment","publication_year":2016,"publication_date":"2016-02-04","ids":{"openalex":"https://openalex.org/W2397039719","doi":"https://doi.org/10.3727/096368915x688263","mag":"2397039719","pmid":"https://pubmed.ncbi.nlm.nih.gov/26065854"},"language":"en","primary_location":{"id":"doi:10.3727/096368915x688263","doi":"https://doi.org/10.3727/096368915x688263","is_oa":true,"landing_page_url":"https://doi.org/10.3727/096368915x688263","pdf_url":"https://journals.sagepub.com/doi/pdf/10.3727/096368915X688263","source":{"id":"https://openalex.org/S165333527","display_name":"Cell Transplantation","issn_l":"0963-6897","issn":["0963-6897","1555-3892"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://journals.sagepub.com/doi/pdf/10.3727/096368915X688263","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090498531","display_name":"Kyung\u2010Sul Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyung-Sul Kim","raw_affiliation_strings":["College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","institution_ids":["https://openalex.org/I4210148737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047293043","display_name":"Ji-Min Park","orcid":"https://orcid.org/0000-0002-8924-2887","observed_orcids":["https://orcid.org/0000-0002-8924-2887"]},"institutions":[{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]},{"id":"https://openalex.org/I4210165484","display_name":"CHA University Gangnam Medical Center","ror":"https://ror.org/05rtdxx03","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4210165484","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji-Min Park","raw_affiliation_strings":["College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","General Research Institute, Gangnam CHA General Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","institution_ids":["https://openalex.org/I4210148737"]},{"raw_affiliation_string":"General Research Institute, Gangnam CHA General Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4210165484"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015217020","display_name":"TaeHo Kong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]},{"id":"https://openalex.org/I4210165484","display_name":"CHA University Gangnam Medical Center","ror":"https://ror.org/05rtdxx03","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4210165484","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Taeho Kong","raw_affiliation_strings":["College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","General Research Institute, Gangnam CHA General Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","institution_ids":["https://openalex.org/I4210148737"]},{"raw_affiliation_string":"General Research Institute, Gangnam CHA General Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4210165484"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100741251","display_name":"Chul Kim","orcid":"https://orcid.org/0000-0003-0191-8684","observed_orcids":["https://orcid.org/0000-0003-0191-8684"]},"institutions":[{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]},{"id":"https://openalex.org/I4210165484","display_name":"CHA University Gangnam Medical Center","ror":"https://ror.org/05rtdxx03","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4210165484","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chul Kim","raw_affiliation_strings":["College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","General Research Institute, Gangnam CHA General Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","institution_ids":["https://openalex.org/I4210148737"]},{"raw_affiliation_string":"General Research Institute, Gangnam CHA General Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4210165484"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002402098","display_name":"Sang\u2010Hun Bae","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]},{"id":"https://openalex.org/I4210165484","display_name":"CHA University Gangnam Medical Center","ror":"https://ror.org/05rtdxx03","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4210165484","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang-Hun Bae","raw_affiliation_strings":["College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","General Research Institute, Gangnam CHA General Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","institution_ids":["https://openalex.org/I4210148737"]},{"raw_affiliation_string":"General Research Institute, Gangnam CHA General Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4210165484"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085539440","display_name":"Han Wool Kim","orcid":"https://orcid.org/0000-0003-3463-3060","observed_orcids":["https://orcid.org/0000-0003-3463-3060"]},"institutions":[{"id":"https://openalex.org/I4210165484","display_name":"CHA University Gangnam Medical Center","ror":"https://ror.org/05rtdxx03","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4210165484","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Han Wool Kim","raw_affiliation_strings":["General Research Institute, Gangnam CHA General Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"General Research Institute, Gangnam CHA General Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4210165484"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080884423","display_name":"Jisook Moon","orcid":"https://orcid.org/0000-0002-7044-4841","observed_orcids":["https://orcid.org/0000-0002-7044-4841"]},"institutions":[{"id":"https://openalex.org/I4210148737","display_name":"CHA University","ror":"https://ror.org/04yka3j04","country_code":"KR","type":"education","lineage":["https://openalex.org/I4210148737","https://openalex.org/I4405258985"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jisook Moon","raw_affiliation_strings":["College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Science, Department of Biotechnology, CHA University, Seoul, Korea","institution_ids":["https://openalex.org/I4210148737"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5080884423"],"corresponding_institution_ids":["https://openalex.org/I4210148737"],"apc_list":{"value":2650,"currency":"USD","value_usd":2650},"apc_paid":null,"fwci":2.2206,"has_fulltext":true,"cited_by_count":51,"citation_normalized_percentile":{"value":0.8638495,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"25","issue":"6","first_page":"1145","last_page":"1157"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.5957000255584717,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.5957000255584717,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.23430000245571136,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.05889999866485596,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinal-angiogenesis","display_name":"retinal angiogenesis","score":0.8460000157356262},{"id":"https://openalex.org/keywords/tgf-beta1","display_name":"TGF-\u03b21","score":0.9850000143051147},{"id":"https://openalex.org/keywords/paracrine-factors","display_name":"paracrine factors","score":0.7519999742507935},{"id":"https://openalex.org/keywords/pathological-neovascularization","display_name":"pathological neovascularization","score":0.8209999799728394},{"id":"https://openalex.org/keywords/proliferative-retinopathy","display_name":"proliferative retinopathy","score":0.9620000123977661},{"id":"https://openalex.org/keywords/oxygen-induced-retinopathy","display_name":"oxygen-induced retinopathy","score":0.9940000176429749},{"id":"https://openalex.org/keywords/endothelial-cell-proliferation","display_name":"endothelial cell proliferation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/retinal-neovascular-disease","display_name":"retinal neovascular disease","score":0.7369999885559082},{"id":"https://openalex.org/keywords/diabetic-retinopathy","display_name":"diabetic retinopathy","score":0.6909999847412109},{"id":"https://openalex.org/keywords/age-related-macular-degeneration","display_name":"age-related macular degeneration","score":0.9670000076293945},{"id":"https://openalex.org/keywords/retinopathy-of-prematurity","display_name":"retinopathy of prematurity","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C2779918416","wikidata":"https://www.wikidata.org/wiki/Q1423087","display_name":"Retinopathy of prematurity","level":4,"score":0.7001741528511047},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.6600249409675598},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.6445099115371704},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.6050029993057251},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.5992245078086853},{"id":"https://openalex.org/C7876069","wikidata":"https://www.wikidata.org/wiki/Q14873666","display_name":"Paracrine signalling","level":3,"score":0.5446214079856873},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.536994457244873},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47042012214660645},{"id":"https://openalex.org/C2778229498","wikidata":"https://www.wikidata.org/wiki/Q24785672","display_name":"Transforming growth factor beta","level":3,"score":0.4305031895637512},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42942002415657043},{"id":"https://openalex.org/C118131993","wikidata":"https://www.wikidata.org/wiki/Q423671","display_name":"Transforming growth factor","level":2,"score":0.4201325476169586},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4085703194141388},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31967782974243164},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3035765290260315},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.23289695382118225},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2184530794620514},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.18218597769737244},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.1488969624042511},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07102829217910767},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.05740123987197876},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000650","descriptor_name":"Amnion","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003930","descriptor_name":"Diabetic Retinopathy","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007274","descriptor_name":"Injections, Intraperitoneal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010920","descriptor_name":"Placenta","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013234","descriptor_name":"Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015861","descriptor_name":"Retinal Neovascularization","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015861","descriptor_name":"Retinal Neovascularization","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D019899","descriptor_name":"Paracrine Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D033581","descriptor_name":"Stem Cell Transplantation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053773","descriptor_name":"Transforming Growth Factor beta1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D059630","descriptor_name":"Mesenchymal Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3727/096368915x688263","doi":"https://doi.org/10.3727/096368915x688263","is_oa":true,"landing_page_url":"https://doi.org/10.3727/096368915x688263","pdf_url":"https://journals.sagepub.com/doi/pdf/10.3727/096368915X688263","source":{"id":"https://openalex.org/S165333527","display_name":"Cell Transplantation","issn_l":"0963-6897","issn":["0963-6897","1555-3892"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Transplantation","raw_type":"journal-article"},{"id":"pmid:26065854","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26065854","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell transplantation","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:3f287acbef444b4f9bc3d517cf14bc04","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/3f287acbef444b4f9bc3d517cf14bc04","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Transplantation, Vol 25 (2016)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3727/096368915x688263","doi":"https://doi.org/10.3727/096368915x688263","is_oa":true,"landing_page_url":"https://doi.org/10.3727/096368915x688263","pdf_url":"https://journals.sagepub.com/doi/pdf/10.3727/096368915X688263","source":{"id":"https://openalex.org/S165333527","display_name":"Cell Transplantation","issn_l":"0963-6897","issn":["0963-6897","1555-3892"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322064","display_name":"Korea Institute for Advancement of Technology","ror":"https://ror.org/015w1qa96"},{"id":"https://openalex.org/F4320322348","display_name":"Korea Science and Engineering Foundation","ror":"https://ror.org/013aysd81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2397039719.pdf","grobid_xml":"https://content.openalex.org/works/W2397039719.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W113410267","https://openalex.org/W1214250537","https://openalex.org/W1538850399","https://openalex.org/W1548867065","https://openalex.org/W1562397511","https://openalex.org/W1568449354","https://openalex.org/W1978999523","https://openalex.org/W1980235826","https://openalex.org/W1986875558","https://openalex.org/W1990076757","https://openalex.org/W2007057348","https://openalex.org/W2007197900","https://openalex.org/W2007722358","https://openalex.org/W2009758003","https://openalex.org/W2021134616","https://openalex.org/W2026744831","https://openalex.org/W2027540026","https://openalex.org/W2036729487","https://openalex.org/W2036835116","https://openalex.org/W2039787319","https://openalex.org/W2045696456","https://openalex.org/W2046433337","https://openalex.org/W2048609378","https://openalex.org/W2049624292","https://openalex.org/W2058785193","https://openalex.org/W2063318180","https://openalex.org/W2078559905","https://openalex.org/W2079121214","https://openalex.org/W2086674933","https://openalex.org/W2089632511","https://openalex.org/W2089663997","https://openalex.org/W2094948130","https://openalex.org/W2100307155","https://openalex.org/W2102144827","https://openalex.org/W2105826477","https://openalex.org/W2114222046","https://openalex.org/W2115078186","https://openalex.org/W2116341181","https://openalex.org/W2118951125","https://openalex.org/W2122107027","https://openalex.org/W2122380860","https://openalex.org/W2128895547","https://openalex.org/W2145775044","https://openalex.org/W2147533029","https://openalex.org/W2156606731","https://openalex.org/W2316067769","https://openalex.org/W2334745886"],"related_works":["https://openalex.org/W2106297200","https://openalex.org/W7153056202","https://openalex.org/W2999667292","https://openalex.org/W2945225742","https://openalex.org/W1969328877","https://openalex.org/W3015165383","https://openalex.org/W7029023990","https://openalex.org/W1971119095","https://openalex.org/W1980147492","https://openalex.org/W2970749910"],"abstract_inverted_index":{"Abnormal":[0],"angiogenesis":[1],"is":[2,147],"a":[3,29,98],"primary":[4],"cause":[5],"of":[6,18,50,62,72,88,101,115,120,126,149,166,171],"many":[7],"eye":[8],"diseases,":[9],"including":[10],"diabetic":[11],"retinopathy,":[12,103],"age-related":[13],"macular":[14],"degeneration,":[15],"and":[16,40,80,111,122,160],"retinopathy":[17,159],"prematurity.":[19],"Mesenchymal":[20],"stem":[21],"cells":[22,90],"(MSCs)":[23],"are":[24,137],"currently":[25],"being":[26],"investigated":[27],"as":[28],"treatment":[30,131,170],"for":[31,168],"several":[32],"such":[33],"retinal":[34,155,172],"diseases":[35],"based":[36],"on":[37,59],"their":[38],"neuroprotective":[39],"angiogenic":[41],"potentials.":[42],"In":[43],"this":[44],"study,":[45],"we":[46],"evaluated":[47],"the":[48,81,86,109,116,123,138,150,163,169],"role":[49],"systemically":[51],"injected":[52,105],"human":[53],"placental":[54],"amniotic":[55],"membrane-derived":[56],"MSCs":[57],"(AMSCs)":[58],"pathological":[60,92],"neovascularization":[61,114,156],"proliferative":[63,158],"retinopathy.":[64],"We":[65],"determined":[66],"that":[67,142],"AMSCs":[68,106,127,146,167],"secrete":[69],"higher":[70],"levels":[71],"transforming":[73],"growth":[74],"factor-\u03b2":[75],"(TGF-\u03b21)":[76],"than":[77],"other":[78],"MSCs,":[79],"secreted":[82,144],"TGF-\u03b21":[83,133,143],"directly":[84],"suppresses":[85],"proliferation":[87],"endothelial":[89],"under":[91],"conditions":[93],"in":[94,97,157],"vitro.":[95],"Moreover,":[96],"mouse":[99],"model":[100],"oxygen-induced":[102],"intraperitoneally":[104],"migrated":[107],"into":[108],"retina":[110],"suppressed":[112],"excessive":[113],"vasculature":[117],"via":[118],"expression":[119],"TGF-\u03b21,":[121],"antineovascular":[124],"effect":[125],"was":[128],"blocked":[129],"by":[130],"with":[132],"siRNA.":[134],"These":[135],"findings":[136],"first":[139],"to":[140,153],"demonstrate":[141],"from":[145],"one":[148],"key":[151],"factors":[152],"suppress":[154],"further":[161],"elucidate":[162],"therapeutic":[164],"function":[165],"neovascular":[173],"diseases.":[174]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}