{"id":"https://openalex.org/W2396824931","doi":"https://doi.org/10.1007/978-3-642-59358-1_61","title":"Cytogenetics for Treatment Stratification in De Novo Adult Acute Myeloid Leukemia","display_name":"Cytogenetics for Treatment Stratification in De Novo Adult Acute Myeloid Leukemia","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2396824931","doi":"https://doi.org/10.1007/978-3-642-59358-1_61","mag":"2396824931"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-59358-1_61","doi":"https://doi.org/10.1007/978-3-642-59358-1_61","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-59358-1_61","pdf_url":null,"source":{"id":"https://openalex.org/S4210221575","display_name":"H\u00e4matologie und Bluttransfusion","issn_l":"0440-0607","issn":["0440-0607"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematology and Blood Transfusion H\u00e4matologie und Bluttransfusion","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2503493641","display_name":"Acute Leukemias IX"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062108544","display_name":"Clara Derber Bloomfield","orcid":"https://orcid.org/0000-0001-5465-7591","observed_orcids":["https://orcid.org/0000-0001-5465-7591"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. D. Bloomfield","raw_affiliation_strings":["The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070476953","display_name":"Kellie J. Archer","orcid":"https://orcid.org/0000-0003-1555-5781","observed_orcids":["https://orcid.org/0000-0003-1555-5781"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. J. Archer","raw_affiliation_strings":["The Cancer and Leukemia Group B Statistical Center, Durham, NC, USA","The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Cancer and Leukemia Group B Statistical Center, Durham, NC, USA","institution_ids":[]},{"raw_affiliation_string":"The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076516238","display_name":"Krzysztof Mr\u00f3zek","orcid":"https://orcid.org/0000-0002-1408-5063","observed_orcids":["https://orcid.org/0000-0002-1408-5063"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. Mr\u00f3zek","raw_affiliation_strings":["The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000921376","display_name":"John C. Byrd","orcid":"https://orcid.org/0000-0001-9830-0711","observed_orcids":["https://orcid.org/0000-0001-9830-0711"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. C. Byrd","raw_affiliation_strings":["The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110107069","display_name":"Susan P. Whitman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. P. Whitman","raw_affiliation_strings":["The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112084922","display_name":"R K Dodge","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R. K. Dodge","raw_affiliation_strings":["The Cancer and Leukemia Group B Statistical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Cancer and Leukemia Group B Statistical Center, Durham, NC, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074089943","display_name":"Andrew J. Carroll","orcid":"https://orcid.org/0000-0001-9844-730X","observed_orcids":["https://orcid.org/0000-0001-9844-730X"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. J. Carroll","raw_affiliation_strings":["Laboratory of Medical Genetics, University of Alabama at Birmingham, Birmingham, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Medical Genetics, University of Alabama at Birmingham, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072420982","display_name":"Richard A. Larson","orcid":"https://orcid.org/0000-0001-9168-3203","observed_orcids":["https://orcid.org/0000-0001-9168-3203"]},"institutions":[{"id":"https://openalex.org/I4210087865","display_name":"University of Chicago Medical Center","ror":"https://ror.org/0076kfe04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087865"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. A. Larson","raw_affiliation_strings":["Section of Hematology/Oncology, Department of Medicine and Cancer Research Center, University of Chicago Medical Center, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Hematology/Oncology, Department of Medicine and Cancer Research Center, University of Chicago Medical Center, Chicago, IL, USA","institution_ids":["https://openalex.org/I4210087865"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049192022","display_name":"Michael A. Caligiuri","orcid":"https://orcid.org/0000-0002-4095-3020","observed_orcids":["https://orcid.org/0000-0002-4095-3020"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. A. Caligiuri","raw_affiliation_strings":["The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.27910686,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"366","last_page":"376"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11215","display_name":"Chronic Myeloid Leukemia Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cytogenetics","display_name":"cytogenetics","score":0.8339999914169312},{"id":"https://openalex.org/keywords/treatment-stratification","display_name":"treatment stratification","score":0.9380000233650208},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9079999923706055},{"id":"https://openalex.org/keywords/17-q22","display_name":"17)(q22","score":0.9409999847412109},{"id":"https://openalex.org/keywords/pml-raralpha","display_name":"PML-RAR\u03b1","score":0.8629999756813049},{"id":"https://openalex.org/keywords/all-trans-retinoic-acid","display_name":"all-trans retinoic acid","score":0.7689999938011169},{"id":"https://openalex.org/keywords/flt3-itd-mutation","display_name":"FLT3-ITD","score":0.8679999709129333},{"id":"https://openalex.org/keywords/flt3-inhibitors","display_name":"FLT3 inhibitors","score":0.9399999976158142},{"id":"https://openalex.org/keywords/normal-cytogenetics","display_name":"normal cytogenetics","score":0.734000027179718}],"concepts":[{"id":"https://openalex.org/C2778041864","wikidata":"https://www.wikidata.org/wiki/Q180983","display_name":"Cytarabine","level":3,"score":0.8924887180328369},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.6547086834907532},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6256340146064758},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6001974940299988},{"id":"https://openalex.org/C174475383","wikidata":"https://www.wikidata.org/wiki/Q246128","display_name":"Cytogenetics","level":4,"score":0.5609256625175476},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.555898129940033},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.5305799841880798},{"id":"https://openalex.org/C2776802502","wikidata":"https://www.wikidata.org/wiki/Q417589","display_name":"Anthracycline","level":4,"score":0.45736250281333923},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.4307061433792114},{"id":"https://openalex.org/C2776611710","wikidata":"https://www.wikidata.org/wiki/Q16888295","display_name":"Induction chemotherapy","level":3,"score":0.4222770929336548},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.40759289264678955},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3798590302467346},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35733842849731445},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.321074903011322},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2449105679988861},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.16318482160568237},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06208565831184387},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-59358-1_61","doi":"https://doi.org/10.1007/978-3-642-59358-1_61","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-59358-1_61","pdf_url":null,"source":{"id":"https://openalex.org/S4210221575","display_name":"H\u00e4matologie und Bluttransfusion","issn_l":"0440-0607","issn":["0440-0607"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Haematology and Blood Transfusion H\u00e4matologie und Bluttransfusion","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W86188056","https://openalex.org/W417406195","https://openalex.org/W1515269506","https://openalex.org/W1523754765","https://openalex.org/W1531963607","https://openalex.org/W1592701464","https://openalex.org/W1919339218","https://openalex.org/W1930980342","https://openalex.org/W1985349116","https://openalex.org/W2004477791","https://openalex.org/W2038528529","https://openalex.org/W2059980831","https://openalex.org/W2076748859","https://openalex.org/W2097583774","https://openalex.org/W2100722219","https://openalex.org/W2112909513","https://openalex.org/W2113367077","https://openalex.org/W2117291755","https://openalex.org/W2117754708","https://openalex.org/W2125676392","https://openalex.org/W2125960056","https://openalex.org/W2129615499","https://openalex.org/W2150113701","https://openalex.org/W2164238912","https://openalex.org/W2314225431","https://openalex.org/W2318674152","https://openalex.org/W2321946412","https://openalex.org/W2329648702","https://openalex.org/W2334200141","https://openalex.org/W2334542393"],"related_works":["https://openalex.org/W2033340973","https://openalex.org/W348959191","https://openalex.org/W2625234132","https://openalex.org/W2158625802","https://openalex.org/W2097583774","https://openalex.org/W1981438266","https://openalex.org/W2041111003","https://openalex.org/W2114165550","https://openalex.org/W2148047805","https://openalex.org/W2890920670"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}