{"id":"https://openalex.org/W2396564766","doi":null,"title":"A Final Common Pathway for Tinnitus - The Medial Temporal Lobe System.","display_name":"A Final Common Pathway for Tinnitus - The Medial Temporal Lobe System.","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W2396564766","mag":"2396564766","pmid":"https://pubmed.ncbi.nlm.nih.gov/10753332"},"language":"en","primary_location":{"id":"pmid:10753332","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10753332","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The international tinnitus journal","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027704212","display_name":"Abraham Shulman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1327163397","display_name":"State University of New York","ror":"https://ror.org/01q1z8k08","country_code":"US","type":"education","lineage":["https://openalex.org/I1327163397"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shulman","raw_affiliation_strings":["Martha Entenmann Tinnitus Center, Health Science Center at Brooklyn, State University of New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Martha Entenmann Tinnitus Center, Health Science Center at Brooklyn, State University of New York, USA","institution_ids":["https://openalex.org/I1327163397"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5027704212"],"corresponding_institution_ids":["https://openalex.org/I1327163397"],"apc_list":null,"apc_paid":null,"fwci":0.4617,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.61999079,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"1","issue":"2","first_page":"115","last_page":"126"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10283","display_name":"Hearing Loss and Rehabilitation","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tinnitus","display_name":"tinnitus","score":1.0},{"id":"https://openalex.org/keywords/final-common-pathway","display_name":"final common pathway","score":0.8960000276565552},{"id":"https://openalex.org/keywords/amygdala","display_name":"amygdala","score":0.8539999723434448},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.9850000143051147},{"id":"https://openalex.org/keywords/spect","display_name":"SPECT","score":0.6449999809265137},{"id":"https://openalex.org/keywords/auditory-memory","display_name":"auditory memory","score":0.6100000143051147},{"id":"https://openalex.org/keywords/auditory-masking","display_name":"auditory masking","score":0.8989999890327454},{"id":"https://openalex.org/keywords/gabaergic-inhibition","display_name":"GABAergic inhibition","score":0.7919999957084656},{"id":"https://openalex.org/keywords/glutamate","display_name":"glutamate","score":0.628000020980835},{"id":"https://openalex.org/keywords/epileptiform-activity","display_name":"epileptiform activity","score":0.8059999942779541}],"concepts":[{"id":"https://openalex.org/C2776992516","wikidata":"https://www.wikidata.org/wiki/Q192309","display_name":"Tinnitus","level":2,"score":0.9380151033401489},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7259794473648071},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5761603116989136},{"id":"https://openalex.org/C2781099131","wikidata":"https://www.wikidata.org/wiki/Q744385","display_name":"Temporal lobe","level":3,"score":0.561318576335907},{"id":"https://openalex.org/C94487597","wikidata":"https://www.wikidata.org/wiki/Q11101","display_name":"Sensory system","level":2,"score":0.5541858673095703},{"id":"https://openalex.org/C2779144063","wikidata":"https://www.wikidata.org/wiki/Q338924","display_name":"Amygdala","level":2,"score":0.5262205600738525},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.4268791377544403},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.4231935739517212},{"id":"https://openalex.org/C541082541","wikidata":"https://www.wikidata.org/wiki/Q192560","display_name":"Limbic system","level":3,"score":0.4157656729221344},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.41081470251083374},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21466168761253357},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.19720458984375},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.19212794303894043},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.11903244256973267}],"mesh":[],"locations_count":2,"locations":[{"id":"pmid:10753332","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10753332","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The international tinnitus journal","raw_type":"Journal Article"},{"id":"mag:2396564766","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10753332","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2417486386","https://openalex.org/W2929665769","https://openalex.org/W2092794451","https://openalex.org/W3159432451","https://openalex.org/W2100732008","https://openalex.org/W1980798536","https://openalex.org/W4254917458","https://openalex.org/W4391965240","https://openalex.org/W4392036443","https://openalex.org/W2001865081"],"abstract_inverted_index":{"A":[0,126],"final":[1,198],"common":[2,199],"pathway":[3,200],"for":[4,10,110,129,201,211],"tinnitus":[5,124],"is":[6,17,90,102,113,136,214],"hypothesized":[7,91,156],"to":[8,23,46,80,138,149,157,160,175],"exist":[9,158],"all":[11,123],"patients":[12],"with":[13,38],"tinnitus.":[14,31,88,111],"Its":[15],"function":[16,95],"the":[18,21,24,28,39,54,63,75,78,81,85,97,103,140,144,147,150,203,206],"transition":[19,76,145],"of":[20,27,30,53,77,84,87,96,105,116,146,166,182,196,205],"sensory":[22,79,148],"affect":[25,82,151],"component":[26],"symptom":[29,86],"Single":[32],"Photon":[33],"Emission":[34],"Computerized":[35],"Tomography":[36],"(SPECT)":[37],"radio":[40],"isotope":[41],"TC99-HMPAO":[42],"has":[43],"identified":[44],"side":[45,47],"perfusion":[48,60],"asymmetries":[49,61],"highlighted":[50,162],"by":[51,163,169],"that":[52,92],"amygdala":[55,98],"-":[56,99],"hippocampal":[57,100],"complex.":[58],"Adjacent":[59],"involving":[62],"frontal,":[64],"temporal":[65],"and":[66,159,208],"parietal":[67],"lobes":[68],"suggest":[69],"a":[70,93,106,114,164,189,197],"interneuronal":[71],"network":[72],"resulting":[73],"in":[74,118,122,143,187],"components":[83],"It":[89,112],"fundamental":[94],"structures":[101],"establishment":[104],"paradoxical":[107,127],"auditory":[108,119,132,191],"memory":[109,128],"result":[115],"alteration":[117],"masking":[120],"found":[121],"patients.":[125],"an":[130],"aberrant":[131],"signal":[133],"i.e.,":[134],"tinnitus,":[135],"considered":[137],"be":[139,161],"initial":[141],"process":[142],"component.":[152],"Underlying":[153],"mechanisms":[154],"are":[155],"diminution":[165],"inhibition":[167,185],"mediated":[168,184],"gamma":[170],"aminobutyric":[171],"acid":[172],"(GABA)":[173],"due":[174],"disconnection":[176],"from":[177],"excitatory":[178],"(glutamate)":[179],"inputs.":[180],"Blockage":[181],"GABA":[183],"results":[186],"Tinnitogenesis,":[188],"epileptiform":[190],"phenomena.":[192],"The":[193],"overall":[194],"hypothesis":[195,213],"tinnitus;":[202],"role":[204],"MTLS;":[207],"clinical":[209],"support":[210],"this":[212],"presented.":[215]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}