{"id":"https://openalex.org/W2396310692","doi":"https://doi.org/10.7314/apjcp.2016.17.3.1009","title":"Effects of TNFalpha, NOS3, MDR1 Gene Polymorphisms on Clinical Parameters, Prognosis and Survival of Multiple Myeloma Cases","display_name":"Effects of TNFalpha, NOS3, MDR1 Gene Polymorphisms on Clinical Parameters, Prognosis and Survival of Multiple Myeloma Cases","publication_year":2016,"publication_date":"2016-04-11","ids":{"openalex":"https://openalex.org/W2396310692","doi":"https://doi.org/10.7314/apjcp.2016.17.3.1009","mag":"2396310692","pmid":"https://pubmed.ncbi.nlm.nih.gov/27039718"},"language":"en","primary_location":{"id":"doi:10.7314/apjcp.2016.17.3.1009","doi":"https://doi.org/10.7314/apjcp.2016.17.3.1009","is_oa":true,"landing_page_url":"https://doi.org/10.7314/apjcp.2016.17.3.1009","pdf_url":"http://koreascience.or.kr:80/article/JAKO201613752758959.pdf","source":{"id":"https://openalex.org/S121579133","display_name":"Asian Pacific Journal of Cancer Prevention","issn_l":"1513-7368","issn":["1513-7368","2476-762X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319060","host_organization_name":"West Asia Organization for Cancer Prevention","host_organization_lineage":["https://openalex.org/P4310319060"],"host_organization_lineage_names":["West Asia Organization for Cancer Prevention"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian Pacific Journal of Cancer Prevention","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://koreascience.or.kr:80/article/JAKO201613752758959.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064161481","display_name":"Cem Basmac\u0131","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59738393","display_name":"Gaziantep University","ror":"https://ror.org/020vvc407","country_code":"TR","type":"education","lineage":["https://openalex.org/I59738393"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"C Basmaci","raw_affiliation_strings":["Department of Hematology, Gaziantep University Faculty of Medicine, Gaziantep,Turkey E-mail : tomatir@pau.edu.tr or aysegaye@hotmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, Gaziantep University Faculty of Medicine, Gaziantep,Turkey E-mail : tomatir@pau.edu.tr or aysegaye@hotmail.com","institution_ids":["https://openalex.org/I59738393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085498128","display_name":"Mustafa Pehl\u0131van","orcid":"https://orcid.org/0000-0002-6692-085X","observed_orcids":["https://orcid.org/0000-0002-6692-085X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Pehlivan","raw_affiliation_strings":["Department of Hematology ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009329417","display_name":"Ag Tomatir","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"AG Tomatir","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113320917","display_name":"T Sever","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59738393","display_name":"Gaziantep University","ror":"https://ror.org/020vvc407","country_code":"TR","type":"education","lineage":["https://openalex.org/I59738393"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"T Sever","raw_affiliation_strings":["Department of Medical Biology and Genetics , Gaziantep University Faculty of Medicine , Gaziantep ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biology and Genetics , Gaziantep University Faculty of Medicine , Gaziantep ,","institution_ids":["https://openalex.org/I59738393"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011557278","display_name":"Vahap Okan","orcid":"https://orcid.org/0000-0002-9869-8181","observed_orcids":["https://orcid.org/0000-0002-9869-8181"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Okan","raw_affiliation_strings":["Department of Hematology ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100622610","display_name":"Mehmet Birhan Y\u0131lmaz","orcid":"https://orcid.org/0000-0002-8169-8628","observed_orcids":["https://orcid.org/0000-0002-8169-8628"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Yilmaz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101425202","display_name":"Sibel O\u011fuzkan Balc\u0131","orcid":"https://orcid.org/0000-0003-0537-3028","observed_orcids":["https://orcid.org/0000-0003-0537-3028"]},"institutions":[{"id":"https://openalex.org/I59738393","display_name":"Gaziantep University","ror":"https://ror.org/020vvc407","country_code":"TR","type":"education","lineage":["https://openalex.org/I59738393"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"S Oguzkan-Balci","raw_affiliation_strings":["Department of Medical Biology and Genetics , Gaziantep University Faculty of Medicine , Gaziantep ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biology and Genetics , Gaziantep University Faculty of Medicine , Gaziantep ,","institution_ids":["https://openalex.org/I59738393"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087123592","display_name":"Sacide Pehl\u0131van","orcid":"https://orcid.org/0000-0003-1272-5845","observed_orcids":["https://orcid.org/0000-0003-1272-5845"]},"institutions":[{"id":"https://openalex.org/I67581229","display_name":"Istanbul University","ror":"https://ror.org/03a5qrr21","country_code":"TR","type":"education","lineage":["https://openalex.org/I67581229"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"S Pehlivan","raw_affiliation_strings":["Department of Medical Biology , Istanbul University , \u0130stanbul Medical Faculty , Istanbul , Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biology , Istanbul University , \u0130stanbul Medical Faculty , Istanbul , Turkey","institution_ids":["https://openalex.org/I67581229"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":200,"currency":"USD","value_usd":200},"apc_paid":{"value":200,"currency":"USD","value_usd":200},"fwci":1.6119,"has_fulltext":true,"cited_by_count":17,"citation_normalized_percentile":{"value":0.8325,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"17","issue":"3","first_page":"1009","last_page":"1014"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":1.0},{"id":"https://openalex.org/keywords/tnf-gene-polymorphism","display_name":"TNF gene polymorphism","score":0.8069999814033508},{"id":"https://openalex.org/keywords/nos3-gene-polymorphism","display_name":"NOS3 gene polymorphism","score":0.9300000071525574},{"id":"https://openalex.org/keywords/mdr1-gene-polymorphism","display_name":"MDR1 gene polymorphism","score":0.9829999804496765},{"id":"https://openalex.org/keywords/nitric-oxide-synthase","display_name":"nitric oxide synthase","score":0.7009999752044678},{"id":"https://openalex.org/keywords/multidrug-resistance","display_name":"multidrug resistance","score":0.6980000138282776},{"id":"https://openalex.org/keywords/tnf-alpha-308","display_name":"TNF-\u03b1 -308","score":0.6460000276565552},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.5680000185966492},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.9800000190734863},{"id":"https://openalex.org/keywords/vad-regimen","display_name":"VAD regimen","score":0.5419999957084656},{"id":"https://openalex.org/keywords/autologous-stem-cell-transplantation","display_name":"autologous stem cell transplantation","score":0.8489999771118164},{"id":"https://openalex.org/keywords/myeloma-pathogenesis","display_name":"myeloma pathogenesis","score":0.7940000295639038}],"concepts":[{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.6739603877067566},{"id":"https://openalex.org/C2777478702","wikidata":"https://www.wikidata.org/wiki/Q419319","display_name":"Bortezomib","level":3,"score":0.6422497034072876},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.6166488528251648},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5576112270355225},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5410164594650269},{"id":"https://openalex.org/C2779609412","wikidata":"https://www.wikidata.org/wiki/Q203174","display_name":"Thalidomide","level":3,"score":0.5371677875518799},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.5322356820106506},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5282266139984131},{"id":"https://openalex.org/C2780401358","wikidata":"https://www.wikidata.org/wiki/Q422252","display_name":"Dexamethasone","level":2,"score":0.5273590683937073},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3564009666442871},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34877723455429077},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.29437559843063354},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2529860734939575},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08975139260292053}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018435","descriptor_name":"ATP Binding Cassette Transporter, Subfamily B","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D052250","descriptor_name":"Nitric Oxide Synthase Type III","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.7314/apjcp.2016.17.3.1009","doi":"https://doi.org/10.7314/apjcp.2016.17.3.1009","is_oa":true,"landing_page_url":"https://doi.org/10.7314/apjcp.2016.17.3.1009","pdf_url":"http://koreascience.or.kr:80/article/JAKO201613752758959.pdf","source":{"id":"https://openalex.org/S121579133","display_name":"Asian Pacific Journal of Cancer Prevention","issn_l":"1513-7368","issn":["1513-7368","2476-762X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319060","host_organization_name":"West Asia Organization for Cancer Prevention","host_organization_lineage":["https://openalex.org/P4310319060"],"host_organization_lineage_names":["West Asia Organization for Cancer Prevention"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian Pacific Journal of Cancer Prevention","raw_type":"journal-article"},{"id":"pmid:27039718","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27039718","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian Pacific journal of cancer prevention : APJCP","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.7314/apjcp.2016.17.3.1009","doi":"https://doi.org/10.7314/apjcp.2016.17.3.1009","is_oa":true,"landing_page_url":"https://doi.org/10.7314/apjcp.2016.17.3.1009","pdf_url":"http://koreascience.or.kr:80/article/JAKO201613752758959.pdf","source":{"id":"https://openalex.org/S121579133","display_name":"Asian Pacific Journal of Cancer Prevention","issn_l":"1513-7368","issn":["1513-7368","2476-762X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319060","host_organization_name":"West Asia Organization for Cancer Prevention","host_organization_lineage":["https://openalex.org/P4310319060"],"host_organization_lineage_names":["West Asia Organization for Cancer Prevention"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Asian Pacific Journal of Cancer Prevention","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320325411","display_name":"Gaziantep \u00dcniversitesi","ror":"https://ror.org/020vvc407"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2396310692.pdf","grobid_xml":"https://content.openalex.org/works/W2396310692.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W103424246","https://openalex.org/W123611820","https://openalex.org/W1580788756","https://openalex.org/W1633951338","https://openalex.org/W1855712432","https://openalex.org/W1948783594","https://openalex.org/W1968295892","https://openalex.org/W1973018387","https://openalex.org/W1974241345","https://openalex.org/W1978409482","https://openalex.org/W1979300931","https://openalex.org/W1997644768","https://openalex.org/W2017657839","https://openalex.org/W2028533496","https://openalex.org/W2029981060","https://openalex.org/W2033283555","https://openalex.org/W2049994208","https://openalex.org/W2074117345","https://openalex.org/W2074881372","https://openalex.org/W2079067931","https://openalex.org/W2090107822","https://openalex.org/W2095675823","https://openalex.org/W2100427463","https://openalex.org/W2102744264","https://openalex.org/W2105437420","https://openalex.org/W2131409791","https://openalex.org/W2137480667","https://openalex.org/W2144668973","https://openalex.org/W2302409177","https://openalex.org/W2313576254","https://openalex.org/W2332648939","https://openalex.org/W2409553680","https://openalex.org/W3041047318","https://openalex.org/W3147894994"],"related_works":["https://openalex.org/W4225164118","https://openalex.org/W2377263462","https://openalex.org/W3198258368","https://openalex.org/W2063255381","https://openalex.org/W2355686865","https://openalex.org/W2086171191","https://openalex.org/W2904762874","https://openalex.org/W2584226673","https://openalex.org/W2753531151","https://openalex.org/W264181858"],"abstract_inverted_index":{"It":[0],"is":[1],"not":[2],"clear":[3],"how":[4],"gene":[5,24,108],"polymorphisms":[6,25,109],"affecting":[7],"drugs":[8],"can":[9],"contributes":[10],"totheir":[11],"efficacy":[12],"in":[13,47,73,129,149,153,169],"multiple":[14],"myeloma":[15,170],"(MM).":[16],"We":[17,66],"here":[18],"aimed":[19],"to":[20,134],"explore":[21],"associations":[22],"among":[23],"of":[26],"tumor":[27],"necrosis":[28],"factor":[29],"alpha":[30],"(TNF\u03b1),":[31],"nitric":[32],"oxide":[33],"synthesis":[34],"3":[35,70],"(NOS3)":[36],"and":[37,45,63,71,78,98,104,106,120,141,161],"multi-drug":[38],"resistance":[39],"1":[40],"(MDR1),":[41],"clinical":[42],"parameters,":[43],"prognosis":[44],"survival":[46],"MM":[48,77,97,131,151],"patients":[49,75],"treated":[50],"with":[51,76,86],"VAD":[52],"(vincristine-adriamycine-dexamethasone),":[53],"MP":[54],"(mephalane-prednisolone),":[55],"autolougus":[56],"stem":[57],"cell":[58],"transplantation":[59],"(ASCT),":[60],"BODEC":[61],"(bortezomib-dexamethasone-cyclophosphamide)":[62],"TD":[64],"(thalidomide-dexamethasone).":[65],"analyzed":[67],"TNF\u03b1,":[68],"NOS":[69],"MDR1":[72,107],"77":[74,79],"healthy":[80,135],"controls.":[81,136],"The":[82],"genotyping":[83],"was":[84,91],"performed":[85],"PCR":[87],"and/or":[88],"PCR-RFLP.":[89],"There":[90],"no":[92],"clinically":[93],"significant":[94],"difference":[95],"between":[96],"control":[99],"groups":[100],"when":[101],"TNF":[102,162],"\u03b1(-238)":[103],"(-857)":[105],"were":[110,126,147],"studied.":[111],"However,":[112],"the":[113,130,150,157],"TNF\u03b1gene":[114],"polymorphism":[115],"(-308)":[116],"GG":[117,144,164],"genotype":[118,124],"(p=0.012)":[119],"NOS3":[121,137,142,158],"(+894)":[122,143,159],"TT":[123,160],"(p=0.008)":[125],"more":[127],"common":[128],"group":[132,152],"compared":[133],"(VNTR)":[138],"AA":[139],"(p=0.007)":[140],"genotypes":[145,165],"(p=0.004)":[146],"decreased":[148],"contrast.":[154],"In":[155],"conclusion,":[156],"\u03b1(-308)":[163],"may":[166],"have":[167],"roles":[168],"pathogenesis.":[171]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}