{"id":"https://openalex.org/W2395918835","doi":null,"title":"[Thromboangiitis obliterans (Buerger's disease). Study of 41 cases].","display_name":"[Thromboangiitis obliterans (Buerger's disease). Study of 41 cases].","publication_year":1993,"publication_date":"1993-09-25","ids":{"openalex":"https://openalex.org/W2395918835","mag":"2395918835","pmid":"https://pubmed.ncbi.nlm.nih.gov/8412397"},"language":"es","primary_location":{"id":"pmid:8412397","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8412397","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicina clinica","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063018579","display_name":"Consuelo Fern\u00e1ndez\u2010Miranda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]},{"id":"https://openalex.org/I4210101691","display_name":"Hospital Universitario 12 De Octubre","ror":"https://ror.org/00qyh5r35","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210101691","https://openalex.org/I4210139293"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"C Fern\u00e1ndez-Miranda","raw_affiliation_strings":["Servicio de Medicina Interna, Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Medicina Interna, Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid","institution_ids":["https://openalex.org/I121748325","https://openalex.org/I4210101691"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089420876","display_name":"R\u00f3mulo Dar\u00edo Vargas Rubio","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Rubio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"J L Vicario","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J L Vicario","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"A Arnaiz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Arnaiz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007742262","display_name":"R Fern\u00e1ndez S\u00e1ez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Fern\u00e1ndez S\u00e1ez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082930849","display_name":"Manuela Mollejo","orcid":"https://orcid.org/0000-0001-5658-0532","observed_orcids":["https://orcid.org/0000-0001-5658-0532"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Mollejo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000764626","display_name":"Federico Pulido","orcid":"https://orcid.org/0000-0002-7414-8812","observed_orcids":["https://orcid.org/0000-0002-7414-8812"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Pulido","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106234250","display_name":"Amalia del Palacio","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A del Palacio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112525712","display_name":"Terryliz Lazaro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T L\u00e1zaro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"101","issue":"9","first_page":"321","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12328","display_name":"Autoimmune and Inflammatory Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10926","display_name":"Peripheral Artery Disease Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thromboangiitis-obliterans","display_name":"thromboangiitis obliterans","score":0.9959999918937683},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.9309999942779541},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.5260000228881836},{"id":"https://openalex.org/keywords/hla-b35","display_name":"HLA-B35","score":0.906000018119812},{"id":"https://openalex.org/keywords/hla-b40","display_name":"HLA-B40","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anticardiolipin-antibodies","display_name":"anticardiolipin antibodies","score":0.9769999980926514},{"id":"https://openalex.org/keywords/mesenteric-ischemia","display_name":"mesenteric ischemia","score":0.875},{"id":"https://openalex.org/keywords/raynaud-s-phenomenon","display_name":"Raynaud's phenomenon","score":0.8700000047683716},{"id":"https://openalex.org/keywords/lower-limb-ischemia","display_name":"lower limb ischemia","score":0.7889999747276306},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.6330000162124634},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.7910000085830688}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9731330871582031},{"id":"https://openalex.org/C2781265703","wikidata":"https://www.wikidata.org/wiki/Q746001","display_name":"Buerger's disease","level":3,"score":0.8053057193756104},{"id":"https://openalex.org/C2776149422","wikidata":"https://www.wikidata.org/wiki/Q377978","display_name":"Thrombophlebitis","level":3,"score":0.6224333047866821},{"id":"https://openalex.org/C2779324797","wikidata":"https://www.wikidata.org/wiki/Q3525982","display_name":"Superficial thrombophlebitis","level":4,"score":0.5409939885139465},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5080785751342773},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.49154672026634216},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.46981361508369446},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4665277600288391},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4577310383319855},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.44445738196372986},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4200168251991272},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.35181957483291626},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1815219521522522}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003094","descriptor_name":"Collagen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013030","descriptor_name":"Spain","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013919","descriptor_name":"Thromboangiitis Obliterans","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013919","descriptor_name":"Thromboangiitis Obliterans","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013919","descriptor_name":"Thromboangiitis Obliterans","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D013919","descriptor_name":"Thromboangiitis Obliterans","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017153","descriptor_name":"Antibodies, Anticardiolipin","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8412397","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8412397","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicina clinica","raw_type":"English Abstract"},{"id":"mag:2395918835","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8412397","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2231820053","https://openalex.org/W1539749918","https://openalex.org/W2903306952","https://openalex.org/W2428414782","https://openalex.org/W2414672135","https://openalex.org/W2069354548","https://openalex.org/W2066193621","https://openalex.org/W2082845630","https://openalex.org/W1604301530","https://openalex.org/W2022010631"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,191,218,230],"aim":[2],"of":[3,17,25,68,89,94,194,215,232,253],"this":[4],"study":[5],"was":[6,73,122,143,161,172,201],"to":[7,37,155,206],"know":[8],"the":[9,38,85,90,95,128,159,164,185,210,243,261],"prevalence,":[10],"clinical":[11,39],"and":[12,15,40,107,119,134,148,168,182,188,209,257],"immunological":[13],"characteristics":[14],"evolution":[16,160],"thromboangiitis":[18,26,222,264],"obliterans.":[19,265],"METHODS:":[20],"Between":[21],"1982-1990":[22],"41":[23,45],"cases":[24,46,63,72,178],"obliterans":[27,223],"were":[28,48,117,138],"diagnosed":[29],"from":[30],"among":[31],"373,899":[32],"patients":[33,86,114,130,165,195,262],"registered":[34],"(11/100,000)":[35],"according":[36],"arteriographic":[41],"criteria.":[42],"Of":[43],"these":[44],"40":[47,71],"males":[49],"with":[50,60,239,263],"mean":[51],"age":[52],"36":[53],"+/-":[54,58,77,81],"7":[55],"years":[56,67],"(mean":[57,80],"SD)":[59],"only":[61],"two":[62],"being":[64],"over":[65],"45":[66],"age.":[69],"In":[70,111,127,157],"followed":[74],"for":[75,124],"44":[76],"29":[78],"months":[79],"SD).":[82],"RESULTS:":[83],"All":[84],"had":[87],"ischemia":[88,208],"lower":[91],"limbs,":[92,97],"34%":[93],"upper":[96],"39%":[98],"superficial":[99],"thrombophlebitis,":[100],"53%":[101],"Raynaud's":[102],"phenomenon,":[103],"5%":[104],"mesenteric":[105,207,244],"ischemia,":[106],"7%":[108],"myocardial":[109],"infarction.":[110],"30":[112],"symptomatic":[113],"anticardiolipin":[115],"antibodies":[116,153,259],"determined":[118,254],"one":[120],"patient":[121],"positive":[123],"IgG":[125],"antibodies.":[126],"23":[129],"in":[131,145,176,183,228,260],"whom":[132,184],"HLA":[133,255],"anticollagen":[135,152,258],"antibody":[136],"studies":[137],"performed":[139],"a":[140,225,250],"significant":[141,251],"increase":[142,252],"found":[144],"HLA-B35,":[146],"HLA-B40":[147],"type":[149],"VI":[150],"denaturalized":[151],"compared":[154],"controls.":[156],"general":[158],"progressive":[162],"when":[163,170,242],"continued":[166],"smoking":[167,181],"favorable":[169],"tobacco":[171],"given":[173],"up":[174,200],"except":[175],"2":[177,204],"who":[179,196],"stopped":[180],"disease":[186,227],"progressed":[187],"death":[189],"occurred.":[190],"total":[192],"number":[193],"died":[197],"during":[198,212],"follow":[199],"3":[202],"(7%),":[203],"due":[205],"third":[211],"i.v.":[213],"infusion":[214],"PGE1.":[216],"CONCLUSIONS:":[217],"results":[219],"demonstrate":[220],"that":[221],"is":[224,235,249],"rare":[226],"Spain.":[229],"involvement":[231],"visceral":[233],"arteries":[234,245],"not":[236],"very":[237],"infrequent":[238],"worse":[240],"prognosis":[241],"are":[246],"involved.":[247],"There":[248],"antigens":[256]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}