{"id":"https://openalex.org/W2395808366","doi":null,"title":"RAD50:n merkitys perinn\u00f6llisess\u00e4 rintasy\u00f6p\u00e4alttiudessa","display_name":"RAD50:n merkitys perinn\u00f6llisess\u00e4 rintasy\u00f6p\u00e4alttiudessa","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2395808366","mag":"2395808366"},"language":"fi","primary_location":{"id":"pmh:oai:tampub.uta.fi:10024/94949","doi":null,"is_oa":false,"landing_page_url":"http://tampub.uta.fi/handle/10024/94949","pdf_url":null,"source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"fi=Syvent\u00e4v\u00e4 ty\u00f6 | en=Master's thesis (medicine)|"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045499940","display_name":"Aune Aho","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Aune Aho","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5045499940"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rad50","display_name":"RAD50","score":0.972000002861023},{"id":"https://openalex.org/keywords/hereditary-breast-cancer","display_name":"hereditary breast cancer","score":0.9620000123977661},{"id":"https://openalex.org/keywords/breast-cancer-susceptibility-genes","display_name":"breast cancer susceptibility genes","score":0.7379999756813049},{"id":"https://openalex.org/keywords/brca1","display_name":"BRCA1","score":0.5960000157356262},{"id":"https://openalex.org/keywords/brca2","display_name":"BRCA2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/novel-mutations","display_name":"novel mutations","score":0.4090000092983246},{"id":"https://openalex.org/keywords/germline-mutations","display_name":"germline mutations","score":0.5789999961853027},{"id":"https://openalex.org/keywords/finnish-women","display_name":"Finnish women","score":0.34599998593330383}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30377358198165894}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:tampub.uta.fi:10024/94949","doi":null,"is_oa":false,"landing_page_url":"http://tampub.uta.fi/handle/10024/94949","pdf_url":null,"source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"fi=Syvent\u00e4v\u00e4 ty\u00f6 | en=Master's thesis (medicine)|"},{"id":"pmh:oai:trepo.tuni.fi:10024/94949","doi":null,"is_oa":false,"landing_page_url":"https://trepo.tuni.fi/handle/10024/94949","pdf_url":null,"source":{"id":"https://openalex.org/S4306401860","display_name":"Tampere University Institutional Repository (Tampere University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150589677","host_organization_name":"Tampere University of Applied Sciences","host_organization_lineage":["https://openalex.org/I150589677"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"fi=Syvent\u00e4v\u00e4 ty\u00f6 | en=Master's thesis (medicine)|"},{"id":"mag:2395808366","doi":null,"is_oa":false,"landing_page_url":"https://tampub.uta.fi/bitstream/handle/10024/94949/SYVENTAVA-1392293272.pdf?sequence=1","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W17660459","https://openalex.org/W1515564094","https://openalex.org/W1520425169","https://openalex.org/W1527133274","https://openalex.org/W1595797072","https://openalex.org/W1946427313","https://openalex.org/W1967513118","https://openalex.org/W1970768715","https://openalex.org/W1972107270","https://openalex.org/W1975919516","https://openalex.org/W1980660634","https://openalex.org/W1981844581","https://openalex.org/W1986610561","https://openalex.org/W1991932352","https://openalex.org/W1994664175","https://openalex.org/W2002150942","https://openalex.org/W2005542290","https://openalex.org/W2006699276","https://openalex.org/W2012506200","https://openalex.org/W2015565457","https://openalex.org/W2017566669","https://openalex.org/W2019460032","https://openalex.org/W2023094419","https://openalex.org/W2023268391","https://openalex.org/W2027806031","https://openalex.org/W2028921845","https://openalex.org/W2029160559","https://openalex.org/W2034750204","https://openalex.org/W2045402712","https://openalex.org/W2046283209","https://openalex.org/W2046848021","https://openalex.org/W2049066045","https://openalex.org/W2049598883","https://openalex.org/W2050657674","https://openalex.org/W2052203436","https://openalex.org/W2052716173","https://openalex.org/W2057165168","https://openalex.org/W2057687275","https://openalex.org/W2064377499","https://openalex.org/W2067993067","https://openalex.org/W2069337540","https://openalex.org/W2074351520","https://openalex.org/W2074754447","https://openalex.org/W2077139148","https://openalex.org/W2082138811","https://openalex.org/W2085501944","https://openalex.org/W2085597296","https://openalex.org/W2094832482","https://openalex.org/W2095834651","https://openalex.org/W2098085059","https://openalex.org/W2101063496","https://openalex.org/W2105182742","https://openalex.org/W2105256330","https://openalex.org/W2106771223","https://openalex.org/W2117298495","https://openalex.org/W2117897733","https://openalex.org/W2118549314","https://openalex.org/W2126282065","https://openalex.org/W2129769331","https://openalex.org/W2130775883","https://openalex.org/W2130883309","https://openalex.org/W2132734902","https://openalex.org/W2133197305","https://openalex.org/W2133429162","https://openalex.org/W2137466745","https://openalex.org/W2137883008","https://openalex.org/W2138974799","https://openalex.org/W2143926802","https://openalex.org/W2145113306","https://openalex.org/W2151786805","https://openalex.org/W2155180800","https://openalex.org/W2155202689","https://openalex.org/W2155974314","https://openalex.org/W2163183874","https://openalex.org/W2166153876","https://openalex.org/W2166752171","https://openalex.org/W2187194727","https://openalex.org/W2330270710"],"related_works":["https://openalex.org/W2547708675","https://openalex.org/W3082555652","https://openalex.org/W7139634693","https://openalex.org/W2279979042","https://openalex.org/W2269898731","https://openalex.org/W7137695945","https://openalex.org/W7163098680","https://openalex.org/W2034750204","https://openalex.org/W7095786383","https://openalex.org/W1026799084"],"abstract_inverted_index":{"Rintasy\u00f6p\u00e4":[0],"on":[1,10],"suomalaisten":[2],"naisten":[3],"yleisin":[4],"sy\u00f6p\u00e4.":[5],"Noin":[6],"75":[7],"%":[8,18,33],"sy\u00f6vist\u00e4":[9],"satunnaisesti":[11],"ilmaantuvia":[12],"eli":[13],"ei-perinn\u00f6llisi\u00e4":[14],"ja":[15,48,66,110,133],"noin":[16,31],"25":[17,108],"perinn\u00f6llisi\u00e4.":[19],"Vain":[20,122],"osa":[21],"perinn\u00f6lliseen":[22],"rintasy\u00f6p\u00e4alttiuteen":[23],"liittyvist\u00e4":[24],"geeneist\u00e4":[25],"tunnetaan.":[26],"BRCA1/2":[27],"-mutaatiot":[28],"selitt\u00e4v\u00e4t":[29],"vain":[30],"20":[32],"korkeasta":[34],"perinn\u00f6llisest\u00e4":[35],"rintasy\u00f6p\u00e4riskist\u00e4":[36],"suomalaisessa":[37],"v\u00e4est\u00f6ss\u00e4.":[38],"Lis\u00e4ksi":[39],"tunnetaan":[40],"useita":[41],"harvinaisia":[42],"geenej\u00e4,":[43,75],"jotka":[44],"vaikuttavat":[45],"yhdess\u00e4":[46],"BRCA1:n":[47],"BRCA2:n":[49],"kanssa,":[50],"mutta":[51],"eiv\u00e4t":[52],"kuitenkaan":[53],"riitt\u00e4v\u00e4sti":[54],"selit\u00e4":[55],"taustaltaan":[56],"ep\u00e4selvi\u00e4":[57],"rintasy\u00f6p\u00e4tapauksia.":[58],"Nykyk\u00e4sityksen":[59],"mukaan":[60],"perinn\u00f6llisen":[61],"rintasy\u00f6v\u00e4n":[62],"taustalta":[63],"l\u00f6ytyy":[64],"korkean":[65],"keskinkertaisen":[67],"rintasy\u00f6p\u00e4riskin":[68],"geenien":[69,83],"lis\u00e4ksi":[70],"runsas":[71],"joukko":[72],"matalan":[73],"riskin":[74,82],"joiden":[76],"vaikutus":[77],"kesken\u00e4\u00e4n":[78],"sek\u00e4":[79],"interaktiot":[80],"korkeamman":[81],"kanssa":[84],"lis\u00e4\u00e4v\u00e4t":[85],"rintasy\u00f6p\u00e4alttiutta.":[86],"Ty\u00f6ss\u00e4":[87],"tutkittiin":[88],"RAD50-":[89],"mutaatioiden":[90],"merkityst\u00e4":[91],"suomalaisv\u00e4est\u00f6n":[92],"korkeassa":[93],"perinn\u00f6llisess\u00e4":[94],"rintasy\u00f6p\u00e4alttiudessa.":[95],"Korkean":[96],"rintasy\u00f6p\u00e4esiintyvyyden":[97],"suvuista":[98],"ker\u00e4tyist\u00e4":[99],"potilasn\u00e4ytteist\u00e4":[100],"etsittiin":[101],"ituradassa":[102],"olevia":[103],"RAD50-geenin":[104],"muutoksia":[105],"sekvensoimalla":[106],"sen":[107,137],"eksonia":[109],"eksoni-introni":[111],"-raja-alueet.":[112],"RAD50:st\u00e4":[113],"l\u00f6ydettiin":[114],"seitsem\u00e4n":[115],"mutaatiota,":[116],"joista":[117],"kolme":[118],"oli":[119,126],"aiemmin":[120],"raportoimattomia.":[121],"yksi":[123],"mutaatioista,":[124],"1544A>G,":[125],"aminohappoa":[127],"vaihtava.":[128],"T\u00e4m\u00e4":[129],"l\u00f6ytyi":[130],"yhdelt\u00e4":[131],"potilaalta":[132],"nelj\u00e4lt\u00e4":[134],"kontrollipotilaalta":[135],"eik\u00e4":[136,148],"arveltu":[138],"lis\u00e4\u00e4v\u00e4n":[139],"rintasy\u00f6p\u00e4riski\u00e4.":[140],"RAD50-muutosten":[141],"tarkemman":[142],"merkityksen":[143],"arvioimiseksi":[144],"vaaditaan":[145],"lis\u00e4\u00e4":[146],"tutkimuksia":[147],"selv\u00e4sti":[149],"perinn\u00f6llist\u00e4":[150],"rintasy\u00f6p\u00e4alttiutta":[151],"lis\u00e4\u00e4vi\u00e4":[152],"mutaatioita":[153],"l\u00f6ydetty.":[154]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}