{"id":"https://openalex.org/W2395796060","doi":null,"title":"Hepatoprotective Activity of Ethanolic Extract of Bacopa monnieri Linn. Aerial Parts Against $CCl_4-induced$ Hepatotoxicity in Rats","display_name":"Hepatoprotective Activity of Ethanolic Extract of Bacopa monnieri Linn. Aerial Parts Against $CCl_4-induced$ Hepatotoxicity in Rats","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W2395796060","mag":"2395796060"},"language":"en","primary_location":{"id":"mag:2395796060","doi":null,"is_oa":false,"landing_page_url":"http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=E1HSBY_2007_v13n1_61","pdf_url":null,"source":{"id":"https://openalex.org/S2764419237","display_name":"Natural Product Sciences","issn_l":"1226-3907","issn":["1226-3907","2288-9027"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","kci-registered","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4366736945","host_organization_name":"Korean Society of Pharmacognosy","host_organization_lineage":["https://openalex.org/P4366736945"],"host_organization_lineage_names":["Korean Society of Pharmacognosy"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Natural Product Sciences","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055498881","display_name":"Tapan Kumar Maity","orcid":"https://orcid.org/0000-0002-3245-7297","observed_orcids":["https://orcid.org/0000-0002-3245-7297"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tapan K. Maity","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3245-7297","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079035421","display_name":"Gouri Kumar Dash","orcid":"https://orcid.org/0000-0001-5439-4162","observed_orcids":["https://orcid.org/0000-0001-5439-4162"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gouri Kumar Dash","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5439-4162","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052333667","display_name":"Anindya Bose","orcid":"https://orcid.org/0000-0002-0111-219X","observed_orcids":["https://orcid.org/0000-0002-0111-219X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anindya Bose","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112130859","display_name":"Siva Sankar Nayak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Siva Sankar Nayak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103966740","display_name":"Deepak Kumar Dash","orcid":"https://orcid.org/0000-0001-7972-9707","observed_orcids":["https://orcid.org/0000-0001-7972-9707"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Deepak Kumar Dash","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112130860","display_name":"Tirtha Ghosh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tirtha Ghosh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2022,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.50133294,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"13","issue":"1","first_page":"61","last_page":"67"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.7484999895095825,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.7484999895095825,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection","score":0.22619999945163727,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bacopa-monnieri","display_name":"Bacopa monnieri","score":1.0},{"id":"https://openalex.org/keywords/hepatoprotective-effect","display_name":"hepatoprotection","score":0.9710000157356262},{"id":"https://openalex.org/keywords/carbon-tetrachloride-hepatotoxicity","display_name":"carbon tetrachloride hepatotoxicity","score":0.9399999976158142},{"id":"https://openalex.org/keywords/ethanolic-plant-extract","display_name":"ethanolic plant extract","score":0.8690000176429749},{"id":"https://openalex.org/keywords/antioxidant-enzymes","display_name":"antioxidant enzymes","score":0.8550000190734863},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.9750000238418579},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9020000100135803},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":1.0},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.9950000047683716},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.6579999923706055},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.6949999928474426},{"id":"https://openalex.org/keywords/liver-histopathology","display_name":"liver histopathology","score":0.8090000152587891},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.7590000033378601}],"concepts":[{"id":"https://openalex.org/C2780433948","wikidata":"https://www.wikidata.org/wiki/Q1366575","display_name":"Bacopa monnieri","level":2,"score":0.9571967124938965},{"id":"https://openalex.org/C2776514860","wikidata":"https://www.wikidata.org/wiki/Q3817359","display_name":"Hepatoprotection","level":4,"score":0.8697165250778198},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.658010721206665},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6478180289268494},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.6331119537353516},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6011738181114197},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.4997432231903076},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.48520758748054504},{"id":"https://openalex.org/C2776637226","wikidata":"https://www.wikidata.org/wiki/Q6658207","display_name":"Liver injury","level":2,"score":0.482572466135025},{"id":"https://openalex.org/C102124568","wikidata":"https://www.wikidata.org/wiki/Q5009626","display_name":"CCL4","level":3,"score":0.4429934620857239},{"id":"https://openalex.org/C2777513400","wikidata":"https://www.wikidata.org/wiki/Q104219","display_name":"Bilirubin","level":2,"score":0.42327550053596497},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.30485010147094727},{"id":"https://openalex.org/C2777359374","wikidata":"https://www.wikidata.org/wiki/Q225045","display_name":"Carbon tetrachloride","level":2,"score":0.3006930351257324},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2957572340965271},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1835847795009613},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1748620867729187},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11044284701347351},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2395796060","doi":null,"is_oa":false,"landing_page_url":"http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=E1HSBY_2007_v13n1_61","pdf_url":null,"source":{"id":"https://openalex.org/S2764419237","display_name":"Natural Product Sciences","issn_l":"1226-3907","issn":["1226-3907","2288-9027"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","kci-registered","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4366736945","host_organization_name":"Korean Society of Pharmacognosy","host_organization_lineage":["https://openalex.org/P4366736945"],"host_organization_lineage_names":["Korean Society of Pharmacognosy"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Natural Product Sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2146919745","https://openalex.org/W1969905898","https://openalex.org/W2010933451","https://openalex.org/W3082781361","https://openalex.org/W2081329803","https://openalex.org/W2296656547","https://openalex.org/W7098929001","https://openalex.org/W2182530350","https://openalex.org/W2483629628","https://openalex.org/W2570432950"],"abstract_inverted_index":{"The":[0,18,47],"ethanolic":[1],"extract":[2,19,48,77,90,115],"of":[3,26,57,64,76,111,113],"Bacopa":[4],"monnieri":[5],"Linn.":[6],"aerial":[7],"parts":[8],"were":[9],"studied":[10],"far":[11],"its":[12,119],"hepatoprotective":[13],"effect":[14,94],"on":[15],"hepatotoxic":[16],"rats.":[17,46,84],"was":[20,49],"found":[21,51],"to":[22,44,52,118],"decrease":[23,53],"significantly":[24,54],"elevation":[25,56],"SGOT,":[27],"SGPT,":[28],"ALP,":[29],"bilirubin":[30],"and":[31,39,60,68,70],"total":[32],"cholesterol.":[33],"But,":[34],"it":[35,104],"increased":[36],"HDL-cholesterol":[37],"level":[38,72],"liver":[40,75,96],"weight":[41],"with":[42,82],"respect":[43],"toxic":[45],"also":[50],"the":[55,62,74,89,100,109,114],"lipid":[58],"peroxidation":[59],"increase":[61],"activity":[63],"antioxidant":[65,120],"enzymes":[66],"(SOD":[67],"CAT)":[69],"GSH":[71],"in":[73],"treated":[78],"rats":[79],"when":[80],"compared":[81],"induced":[83],"Histopatholosical":[85],"profiles":[86],"showed":[87],"that":[88,108],"had":[91],"significant":[92],"protective":[93],"against":[95],"injury,":[97],"which":[98],"corroborates":[99],"above":[101],"findings.":[102],"Hence":[103],"may":[105],"be":[106],"possible":[107],"mechanism":[110],"hepatoprotection":[112],"is":[116],"due":[117],"effect.":[121]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-02T10:15:12.560889","created_date":"2016-06-24T00:00:00"}