{"id":"https://openalex.org/W2395090290","doi":"https://doi.org/10.1080/09168451.2016.1184963","title":"Identification of a mutation causing a defective spindle assembly checkpoint in high ethyl caproate-producing sake yeast strain K1801","display_name":"Identification of a mutation causing a defective spindle assembly checkpoint in high ethyl caproate-producing sake yeast strain K1801","publication_year":2016,"publication_date":"2016-05-18","ids":{"openalex":"https://openalex.org/W2395090290","doi":"https://doi.org/10.1080/09168451.2016.1184963","mag":"2395090290","pmid":"https://pubmed.ncbi.nlm.nih.gov/27191586"},"language":"en","primary_location":{"id":"doi:10.1080/09168451.2016.1184963","doi":"https://doi.org/10.1080/09168451.2016.1184963","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09168451.2016.1184963","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/09168451.2016.1184963?needAccess=true","source":{"id":"https://openalex.org/S94095188","display_name":"Bioscience Biotechnology and Biochemistry","issn_l":"0916-8451","issn":["0916-8451","1347-6947"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, Biotechnology, and Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/09168451.2016.1184963?needAccess=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031833659","display_name":"Tetsuya Goshima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210148523","display_name":"National Research Institute of Brewing","ror":"https://ror.org/04wd29d63","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210148523"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Tetsuya Goshima","raw_affiliation_strings":["National Research Institute of Brewing, Higashi-Hiroshima, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Research Institute of Brewing, Higashi-Hiroshima, Japan","institution_ids":["https://openalex.org/I4210148523"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103985264","display_name":"Ryo Nakamura","orcid":"https://orcid.org/0009-0009-0858-1229","observed_orcids":["https://orcid.org/0009-0009-0858-1229"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryo Nakamura","raw_affiliation_strings":["Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan","Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062105936","display_name":"Kazunori Kume","orcid":"https://orcid.org/0000-0002-0613-8081","observed_orcids":["https://orcid.org/0000-0002-0613-8081"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazunori Kume","raw_affiliation_strings":["Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013707634","display_name":"Hiroki Okada","orcid":"https://orcid.org/0000-0001-8428-2559","observed_orcids":["https://orcid.org/0000-0001-8428-2559","https://orcid.org/0009-0003-2501-3684"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Hiroki Okada","raw_affiliation_strings":["Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA","Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell and Developmental Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045317940","display_name":"Eri Ichikawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eri Ichikawa","raw_affiliation_strings":["Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108680327","display_name":"Hiroyasu Tamura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroyasu Tamura","raw_affiliation_strings":["Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hirokazu Hasuda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256366","display_name":"Brewing Society of Japan","ror":"https://ror.org/042q4kf72","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I4405256366"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirokazu Hasuda","raw_affiliation_strings":["Brewing Society of Japan, Kita-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brewing Society of Japan, Kita-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4405256366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057950332","display_name":"Masaaki INAHASHI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256366","display_name":"Brewing Society of Japan","ror":"https://ror.org/042q4kf72","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I4405256366"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaaki Inahashi","raw_affiliation_strings":["Brewing Society of Japan, Kita-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brewing Society of Japan, Kita-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4405256366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023726279","display_name":"Naoto OKAZAKI","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405256366","display_name":"Brewing Society of Japan","ror":"https://ror.org/042q4kf72","country_code":"JP","type":"nonprofit","lineage":["https://openalex.org/I4405256366"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naoto Okazaki","raw_affiliation_strings":["Brewing Society of Japan, Kita-ku, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brewing Society of Japan, Kita-ku, Tokyo, Japan","institution_ids":["https://openalex.org/I4405256366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081400256","display_name":"Takeshi Akao","orcid":"https://orcid.org/0000-0003-2784-2016","observed_orcids":["https://orcid.org/0000-0003-2784-2016"]},"institutions":[{"id":"https://openalex.org/I4210148523","display_name":"National Research Institute of Brewing","ror":"https://ror.org/04wd29d63","country_code":"JP","type":"government","lineage":["https://openalex.org/I4210148523"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeshi Akao","raw_affiliation_strings":["National Research Institute of Brewing, Higashi-Hiroshima, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Research Institute of Brewing, Higashi-Hiroshima, Japan","institution_ids":["https://openalex.org/I4210148523"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090232193","display_name":"Hitoshi Shimoi","orcid":"https://orcid.org/0000-0002-0397-1764","observed_orcids":["https://orcid.org/0000-0002-0397-1764"]},"institutions":[{"id":"https://openalex.org/I173009982","display_name":"Iwate University","ror":"https://ror.org/04cd75h10","country_code":"JP","type":"education","lineage":["https://openalex.org/I173009982"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitoshi Shimoi","raw_affiliation_strings":["Department of Biological Chemistry and Food Sciences, Iwate University, Morioka, Iwate, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Chemistry and Food Sciences, Iwate University, Morioka, Iwate, Japan","institution_ids":["https://openalex.org/I173009982"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019595050","display_name":"Masaki Mizunuma","orcid":"https://orcid.org/0000-0002-1531-1763","observed_orcids":["https://orcid.org/0000-0002-1531-1763"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaki Mizunuma","raw_affiliation_strings":["Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060486921","display_name":"Yoshikazu Ohya","orcid":"https://orcid.org/0000-0003-0837-1239","observed_orcids":["https://orcid.org/0000-0003-0837-1239"]},"institutions":[{"id":"https://openalex.org/I74801974","display_name":"The University of Tokyo","ror":"https://ror.org/057zh3y96","country_code":"JP","type":"education","lineage":["https://openalex.org/I74801974"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshikazu Ohya","raw_affiliation_strings":["Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrated Biosciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan","institution_ids":["https://openalex.org/I74801974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110781640","display_name":"Dai Hirata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Dai Hirata","raw_affiliation_strings":["Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan","Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, Higashi-Hiroshima, Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Research and Development Department, Asahi Sake Brewing Co. Ltd., Nagaoka, Niigata, Japan","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5031833659","https://openalex.org/A5110781640"],"corresponding_institution_ids":["https://openalex.org/I113306721","https://openalex.org/I4210148523"],"apc_list":{"value":3272,"currency":"USD","value_usd":3272},"apc_paid":null,"fwci":1.3071,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.78970841,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"80","issue":"8","first_page":"1657","last_page":"1662"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.7407000064849854,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.7407000064849854,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics","score":0.20340000092983246,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10750","display_name":"Fermentation and Sensory Analysis","score":0.01860000006854534,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spindle-assembly-checkpoint","display_name":"spindle assembly checkpoint","score":0.9390000104904175},{"id":"https://openalex.org/keywords/sake-yeast","display_name":"sake yeast","score":0.5989999771118164},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.8870000243186951},{"id":"https://openalex.org/keywords/cdc55","display_name":"Cdc55","score":0.8640000224113464},{"id":"https://openalex.org/keywords/yeast-breeding","display_name":"yeast breeding","score":0.4429999887943268},{"id":"https://openalex.org/keywords/mutation-detection","display_name":"mutation detection","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.7411256432533264},{"id":"https://openalex.org/C175732170","wikidata":"https://www.wikidata.org/wiki/Q9064829","display_name":"Spindle checkpoint","level":5,"score":0.728812038898468},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6115663647651672},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6035161018371582},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.4527178704738617},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.43950018286705017},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.43645644187927246},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.36435890197753906},{"id":"https://openalex.org/C192838845","wikidata":"https://www.wikidata.org/wiki/Q908912","display_name":"Kinetochore","level":4,"score":0.2016264796257019},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.1365993618965149},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000434","descriptor_name":"Alcoholic Beverages","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002208","descriptor_name":"Caproates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005285","descriptor_name":"Fermentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005524","descriptor_name":"Food Technology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009812","descriptor_name":"Odorants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012275","descriptor_name":"Oryza","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012641","descriptor_name":"Selection, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018797","descriptor_name":"Cell Cycle Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018797","descriptor_name":"Cell Cycle Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054648","descriptor_name":"Protein Phosphatase 2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D054648","descriptor_name":"Protein Phosphatase 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059566","descriptor_name":"M Phase Cell Cycle Checkpoints","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1080/09168451.2016.1184963","doi":"https://doi.org/10.1080/09168451.2016.1184963","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09168451.2016.1184963","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/09168451.2016.1184963?needAccess=true","source":{"id":"https://openalex.org/S94095188","display_name":"Bioscience Biotechnology and Biochemistry","issn_l":"0916-8451","issn":["0916-8451","1347-6947"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, Biotechnology, and Biochemistry","raw_type":"journal-article"},{"id":"pmid:27191586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27191586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, biotechnology, and biochemistry","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1080/09168451.2016.1184963","doi":"https://doi.org/10.1080/09168451.2016.1184963","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09168451.2016.1184963","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/09168451.2016.1184963?needAccess=true","source":{"id":"https://openalex.org/S94095188","display_name":"Bioscience Biotechnology and Biochemistry","issn_l":"0916-8451","issn":["0916-8451","1347-6947"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioscience, Biotechnology, and Biochemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4597446107","display_name":null,"funder_award_id":"15H04402 to Y.O.","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"},{"id":"https://openalex.org/G5309241283","display_name":"Elucidation of the working principle of cells based on high dimensional phenotyping","funder_award_id":"15H04402","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2395090290.pdf"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1031782815","https://openalex.org/W1963750681","https://openalex.org/W1971302364","https://openalex.org/W1971335607","https://openalex.org/W1973916918","https://openalex.org/W1993935814","https://openalex.org/W1995341440","https://openalex.org/W2008647073","https://openalex.org/W2031523570","https://openalex.org/W2037728125","https://openalex.org/W2048938594","https://openalex.org/W2060113364","https://openalex.org/W2073958776","https://openalex.org/W2113439921","https://openalex.org/W2132353659","https://openalex.org/W2133422502","https://openalex.org/W2151385152"],"related_works":["https://openalex.org/W4411755760","https://openalex.org/W2008647073","https://openalex.org/W1991173338","https://openalex.org/W1995341440","https://openalex.org/W1516567367","https://openalex.org/W4406721759","https://openalex.org/W1981121252","https://openalex.org/W2515737043","https://openalex.org/W2301779989","https://openalex.org/W3132521877"],"abstract_inverted_index":{"In":[0],"high-quality":[1],"sake":[2,6,38,72],"brewing,":[3],"the":[4,29,81,90,96,102,128],"cerulenin-resistant":[5],"yeast":[7],"K1801":[8,19,44,62,105,146],"with":[9,40,147],"high":[10,118],"ethyl":[11],"caproate-producing":[12],"ability":[13],"has":[14,20],"been":[15],"used":[16],"widely;":[17],"however,":[18],"a":[21,41,51,57,117,138,143],"defective":[22],"spindle":[23],"assembly":[24],"checkpoint":[25,149],"(SAC).":[26],"To":[27],"identify":[28],"mutation":[30,98,115,124,136],"causing":[31],"this":[32,114,123,135],"defect,":[33],"we":[34,54,93],"first":[35],"searched":[36,55],"for":[37,56,89,101,140],"yeasts":[39],"SAC-defect":[42,103],"like":[43],"and":[45,63,74],"found":[46,75],"that":[47,86,95,113],"K13":[48,64],"had":[49],"such":[50],"defect.":[52],"Then,":[53],"common":[58],"SNP":[59],"in":[60,70,104],"only":[61],"by":[65,106],"examining":[66],"15":[67],"checkpoint-related":[68],"genes":[69],"23":[71],"yeasts,":[73],"1":[76],"mutation,":[77],"R48P":[78],"of":[79,132,142],"Cdc55,":[80],"PP2A":[82],"regulatory":[83],"B":[84],"subunit":[85],"is":[87,137],"important":[88],"SAC.":[91],"Furthermore,":[92],"confirmed":[94],"Cdc55-R48P":[97],"was":[99],"responsible":[100],"molecular":[107],"genetic":[108],"analyses.":[109],"Morphological":[110],"analysis":[111],"indicated":[112],"caused":[116],"cell":[119],"morphological":[120],"variation.":[121],"But":[122],"did":[125],"not":[126],"affect":[127],"excellent":[129],"brewing":[130],"properties":[131],"K1801.":[133],"Thus,":[134],"target":[139],"breeding":[141],"new":[144],"risk-free":[145],"normal":[148],"integrity.":[150]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}