{"id":"https://openalex.org/W2395065047","doi":null,"title":"Analysis of rare high-DNA cell populations in serous effusions using continuous-motion imaging.","display_name":"Analysis of rare high-DNA cell populations in serous effusions using continuous-motion imaging.","publication_year":1991,"publication_date":"1991-07-01","ids":{"openalex":"https://openalex.org/W2395065047","mag":"2395065047","pmid":"https://pubmed.ncbi.nlm.nih.gov/1883747"},"language":"en","primary_location":{"id":"pmid:1883747","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1883747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology","raw_type":"Comparative Study"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"J H Tucker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387154614","display_name":"MRC Human Genetics Unit","ror":"https://ror.org/011jsc803","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4387154614","https://openalex.org/I90344618","https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J H Tucker","raw_affiliation_strings":["Medical Research Council, Human Genetics Unit, Edinburgh, Scotland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Research Council, Human Genetics Unit, Edinburgh, Scotland","institution_ids":["https://openalex.org/I4387154614"]}]},{"author_position":"middle","author":{"id":null,"display_name":"M H Stark","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M H Stark","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063414506","display_name":"P Eason","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Eason","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5085894596","display_name":"Edward Duvall","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Duvall","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28775056,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"4","first_page":"233","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.6791999936103821,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.6791999936103821,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.2053000032901764,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.030899999663233757,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serous-effusions","display_name":"serous effusions","score":0.8550000190734863},{"id":"https://openalex.org/keywords/dna-ploidy","display_name":"DNA ploidy","score":0.8040000200271606},{"id":"https://openalex.org/keywords/malignancy-diagnosis","display_name":"malignancy diagnosis","score":0.6439999938011169},{"id":"https://openalex.org/keywords/cytopathology","display_name":"cytopathology","score":0.6579999923706055},{"id":"https://openalex.org/keywords/discriminant-classification","display_name":"discriminant classification","score":0.6069999933242798}],"concepts":[{"id":"https://openalex.org/C150173356","wikidata":"https://www.wikidata.org/wiki/Q6144101","display_name":"Serous fluid","level":2,"score":0.8137488961219788},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5862262845039368},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5102729797363281},{"id":"https://openalex.org/C122048520","wikidata":"https://www.wikidata.org/wiki/Q2913954","display_name":"Percentile","level":2,"score":0.4840211570262909},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.47017043828964233},{"id":"https://openalex.org/C163430725","wikidata":"https://www.wikidata.org/wiki/Q424532","display_name":"Effusion","level":2,"score":0.4593939781188965},{"id":"https://openalex.org/C89838059","wikidata":"https://www.wikidata.org/wiki/Q623738","display_name":"Coefficient of variation","level":2,"score":0.4419456124305725},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3680565059185028},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.34140127897262573},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12455043196678162},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.10659891366958618},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.06911781430244446},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000230","descriptor_name":"Adenocarcinoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001202","descriptor_name":"Ascitic Fluid","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003581","descriptor_name":"Cytodiagnosis","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010534","descriptor_name":"Peritoneal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D010996","descriptor_name":"Pleural Effusion","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011003","descriptor_name":"Ploidies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1883747","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1883747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology","raw_type":"Comparative Study"},{"id":"mag:2395065047","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1883747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2378920291","https://openalex.org/W2443243767","https://openalex.org/W2046452438","https://openalex.org/W2386908297","https://openalex.org/W2050159139","https://openalex.org/W2408186702","https://openalex.org/W2012720238","https://openalex.org/W1521010567","https://openalex.org/W3196788641","https://openalex.org/W1994493777"],"abstract_inverted_index":{"The":[0,102,124],"rare":[1],"high-DNA":[2,168],"cell":[3,169],"sub-populations":[4],"in":[5,50,175,180],"a":[6,21,100,127,153],"series":[7],"of":[8,27,55,76,91,109,121,130,166,173,178],"serous":[9,181],"effusion":[10,182],"specimens":[11,30],"were":[12,35,57],"analysed":[13],"to":[14,43],"determine":[15],"whether":[16],"such":[17],"measurements":[18],"could":[19,171],"provide":[20],"basis":[22],"for":[23,59,105],"the":[24,38,47,51,60,69,77,89,92,118,134,142,164,167,176],"improved":[25],"diagnosis":[26,177],"malignancy.":[28],"Monolayer":[29],"stained":[31],"with":[32,37,117],"gallocyanin":[33],"chrome-alum":[34],"scanned":[36],"CERVIFIP":[39],"continuous-motion":[40],"image":[41],"analyser":[42],"locate":[44],"and":[45,82],"measure":[46],"highest-DNA":[48],"cells":[49,79,93],"sample.":[52],"Two":[53],"types":[54],"features":[56,111],"obtained":[58,114],"detected":[61],"sub-populations;":[62],"firstly,":[63],"'percentile":[64],"ploidy'":[65],"values":[66,86],"which":[67,73,87],"characterise":[68,88],"ploidy":[70,137],"levels":[71],"above":[72],"specified":[74],"proportions":[75],"total":[78],"are":[80],"found;":[81],"secondly":[83],"'percentage":[84],"abnormal'":[85],"proportion":[90],"diagnosed":[94],"as":[95],"malignant":[96],"during":[97],"examination":[98],"by":[99,115],"cytopathologist.":[101],"classification":[103,128],"accuracy":[104],"one":[106],"or":[107],"both":[108,157],"these":[110],"was":[112,160],"then":[113],"comparison":[116],"clinical":[119],"outcome":[120],"each":[122],"patient.":[123],"results":[125],"gave":[126],"error":[129],"9/44":[131],"(20%)":[132],"using":[133,141,156],"0.01%":[135],"percentile":[136],"alone,":[138,147],"6/44":[139],"(14%)":[140],"75%":[143],"percentage":[144],"abnormal":[145],"feature":[146],"but":[148],"only":[149],"2/44":[150],"(5%)":[151],"from":[152],"box":[154],"discriminant":[155],"features.":[158],"It":[159],"therefore":[161],"concluded":[162],"that":[163],"analysis":[165],"population":[170],"be":[172],"value":[174],"malignancy":[179],"specimens.":[183]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}