{"id":"https://openalex.org/W2394952178","doi":null,"title":"[Layer I neurons and their significance in the neocortex embryogenesis].","display_name":"[Layer I neurons and their significance in the neocortex embryogenesis].","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2394952178","mag":"2394952178","pmid":"https://pubmed.ncbi.nlm.nih.gov/12596546"},"language":"ru","primary_location":{"id":"pmid:12596546","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12596546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Morfologiia (Saint Petersburg, Russia)","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054082282","display_name":"V. E. Okhotin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110167","display_name":"Institute of Gene Biology","ror":"https://ror.org/01yq9ya27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110167","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"V E Okhotin","raw_affiliation_strings":["Laboratory of Neurogenetics and Developmental Genetics, Institute of Gene Biology, RAS, Moscow"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Neurogenetics and Developmental Genetics, Institute of Gene Biology, RAS, Moscow","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029853825","display_name":"Sergei G. Kalinichenko","orcid":"https://orcid.org/0000-0002-1434-765X","observed_orcids":["https://orcid.org/0000-0002-1434-765X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S G Kalinichenko","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.24005891,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"122","issue":"4","first_page":"7","last_page":"26"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cajal-retzius-cells","display_name":"Cajal-Retzius cells","score":0.8970000147819519},{"id":"https://openalex.org/keywords/cortical-plate","display_name":"cortical plate","score":0.4690000116825104},{"id":"https://openalex.org/keywords/marginal-zone","display_name":"marginal zone","score":0.4729999899864197},{"id":"https://openalex.org/keywords/plexiform-layer","display_name":"plexiform layer","score":0.7379999756813049},{"id":"https://openalex.org/keywords/neocortex","display_name":"neocortex","score":0.6769999861717224},{"id":"https://openalex.org/keywords/pyramidal-neurons","display_name":"pyramidal neurons","score":0.7490000128746033},{"id":"https://openalex.org/keywords/non-pyramidal-neurons","display_name":"non-pyramidal neurons","score":0.9959999918937683},{"id":"https://openalex.org/keywords/thalamocortical-afferents","display_name":"thalamocortical afferents","score":0.8560000061988831},{"id":"https://openalex.org/keywords/cortical-maturation","display_name":"cortical maturation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/cortical-areas","display_name":"cortical regions","score":0.4320000112056732},{"id":"https://openalex.org/keywords/cerebral-hemispheres","display_name":"cerebral hemispheres","score":0.7680000066757202},{"id":"https://openalex.org/keywords/cortical-microarchitecture","display_name":"cortical microarchitecture","score":0.4259999990463257},{"id":"https://openalex.org/keywords/mammalian-evolution","display_name":"mammalian evolution","score":0.43799999356269836}],"concepts":[{"id":"https://openalex.org/C2777222312","wikidata":"https://www.wikidata.org/wiki/Q726562","display_name":"Neocortex","level":2,"score":0.9466394186019897},{"id":"https://openalex.org/C108619961","wikidata":"https://www.wikidata.org/wiki/Q5173281","display_name":"Corticogenesis","level":4,"score":0.7770355939865112},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6969113349914551},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6929113268852234},{"id":"https://openalex.org/C184750944","wikidata":"https://www.wikidata.org/wiki/Q557677","display_name":"Primordium","level":3,"score":0.6107713580131531},{"id":"https://openalex.org/C2779409897","wikidata":"https://www.wikidata.org/wiki/Q7631811","display_name":"Subplate","level":3,"score":0.5747656226158142},{"id":"https://openalex.org/C39961270","wikidata":"https://www.wikidata.org/wiki/Q2927095","display_name":"Neuroblast","level":3,"score":0.5740452408790588},{"id":"https://openalex.org/C37291498","wikidata":"https://www.wikidata.org/wiki/Q193603","display_name":"Ontogeny","level":2,"score":0.5323999524116516},{"id":"https://openalex.org/C2779263132","wikidata":"https://www.wikidata.org/wiki/Q2215671","display_name":"Afferent","level":2,"score":0.505301296710968},{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.48527881503105164},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.4835219383239746},{"id":"https://openalex.org/C2781041448","wikidata":"https://www.wikidata.org/wiki/Q75839","display_name":"Cerebral cortex","level":2,"score":0.4474864602088928},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.44213566184043884},{"id":"https://openalex.org/C2778173225","wikidata":"https://www.wikidata.org/wiki/Q972250","display_name":"Central sulcus","level":4,"score":0.41603347659111023},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.23025467991828918},{"id":"https://openalex.org/C2778373776","wikidata":"https://www.wikidata.org/wiki/Q18696","display_name":"Motor cortex","level":3,"score":0.1817488670349121},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005075","descriptor_name":"Biological Evolution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017966","descriptor_name":"Pyramidal Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D019579","descriptor_name":"Neocortex","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D019579","descriptor_name":"Neocortex","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D019579","descriptor_name":"Neocortex","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:12596546","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12596546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Morfologiia (Saint Petersburg, Russia)","raw_type":"English Abstract"},{"id":"mag:2394952178","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12596546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2087803822","https://openalex.org/W2035017467","https://openalex.org/W2098862557","https://openalex.org/W319363552","https://openalex.org/W90385670","https://openalex.org/W1998428883","https://openalex.org/W2035017568","https://openalex.org/W2885561873","https://openalex.org/W2025290781","https://openalex.org/W1966927218"],"abstract_inverted_index":{"The":[0,80,130],"literature":[1],"data":[2],"and":[3,14,41,50,70,97,120,128,140],"the":[4,27,162],"results":[5],"of":[6,16,21,30,39,52,57,74,83,88,95,103,106,114,117,122,137,147,153],"authors":[7],"own":[8],"investigations":[9],"are":[10],"presented":[11,91],"on":[12],"microarchitectonics":[13],"development":[15],"molecular":[17],"layer":[18],"(layer":[19],"I)":[20],"mammalian":[22,126],"neocortex.":[23],"It":[24],"originates":[25],"from":[26,161],"marginal":[28],"zone":[29],"primordial":[31],"plexiform":[32],"layer,":[33],"common":[34],"with":[35,64,150],"primitive":[36],"neopallial":[37],"primordium":[38],"reptiles":[40],"amphibia,":[42],"which":[43,67,134],"maintains":[44],"its":[45],"initial":[46,55],"organization":[47],"during":[48],"phylo-":[49],"ontogenesis":[51,127],"vertebrates.":[53],"During":[54],"stages":[56],"corticogenesis":[58],"all":[59],"migrating":[60],"neurons":[61,142],"establish":[62],"contacts":[63,149],"Cajal-Retzius":[65],"cells":[66],"coordinate":[68],"location":[69],"exact":[71],"spatial":[72],"stratification":[73],"neuroblasts":[75],"in":[76,125],"growing":[77],"cortical":[78,118,169],"plate.":[79],"detailed":[81],"analysis":[82],"fundamental":[84],"mechanisms":[85],"controlling":[86],"embryogenesis":[87],"neocortex":[89,107],"is":[90,157],"including":[92],"a)":[93],"histogenesis":[94],"pyramidal":[96,139],"non-pyramidal":[98,141],"neurons;":[99],"b)":[100],"unifying":[101],"theory":[102],"cytoarchitectonic":[104,115],"differentiation":[105,116],"proposed":[108],"by":[109],"M.":[110],"Marin-Padilla;":[111],"c)":[112],"factors":[113],"areas":[119],"specialization":[121],"brain":[123],"hemispheres":[124],"evolution.":[129],"thesis,":[131],"according":[132],"to":[133],"morphofunctional":[135],"maturation":[136,170],"both":[138],"begins":[143],"as":[144],"a":[145,151],"result":[146],"their":[148],"system":[152],"thalamocortical":[154],"afferent":[155],"fibers,":[156],"substantiated.":[158],"They":[159],"grow":[160],"subcortical":[163],"white":[164],"matter,":[165],"initiate":[166],"layer-by-layer":[167],"ascending":[168],"and,":[171],"ultimately,":[172],"divide":[173],"it":[174],"into":[175],"descrete":[176],"functional":[177],"territories.":[178]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}