{"id":"https://openalex.org/W2394857857","doi":"https://doi.org/10.1194/jlr.m058586","title":"Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity","display_name":"Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity","publication_year":2015,"publication_date":"2015-04-04","ids":{"openalex":"https://openalex.org/W2394857857","doi":"https://doi.org/10.1194/jlr.m058586","mag":"2394857857","pmid":"https://pubmed.ncbi.nlm.nih.gov/25842377","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4442873"},"language":"en","primary_location":{"id":"doi:10.1194/jlr.m058586","doi":"https://doi.org/10.1194/jlr.m058586","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.m058586","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1194/jlr.m058586","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041070834","display_name":"John D. Douglass","orcid":"https://orcid.org/0000-0001-9508-2819","observed_orcids":["https://orcid.org/0000-0001-9508-2819"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John D. Douglass","raw_affiliation_strings":["Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027609269","display_name":"Yin Xiu Zhou","orcid":"https://orcid.org/0000-0003-4008-7334","observed_orcids":["https://orcid.org/0000-0003-4008-7334"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yin Xiu Zhou","raw_affiliation_strings":["Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077438718","display_name":"Amy Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy Wu","raw_affiliation_strings":["Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040437002","display_name":"John A. Zadrogra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John A. Zadrogra","raw_affiliation_strings":["Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073438504","display_name":"Angela M. Gajda","orcid":"https://orcid.org/0000-0002-5374-2054","observed_orcids":["https://orcid.org/0000-0002-5374-2054"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angela M. Gajda","raw_affiliation_strings":["Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064502107","display_name":"Atreju I. Lackey","orcid":"https://orcid.org/0000-0002-7474-2766","observed_orcids":["https://orcid.org/0000-0002-7474-2766"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Atreju I. Lackey","raw_affiliation_strings":["Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067320228","display_name":"Wensheng Lang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282460","display_name":"Janssen Research & Development (United States)","ror":"https://ror.org/05wae1a98","country_code":"US","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I4405282460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wensheng Lang","raw_affiliation_strings":["Janssen Research & Development, LLC, Spring House, PA 19477"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development, LLC, Spring House, PA 19477","institution_ids":["https://openalex.org/I4405282460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046391855","display_name":"Kristen M. Chevalier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282460","display_name":"Janssen Research & Development (United States)","ror":"https://ror.org/05wae1a98","country_code":"US","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I4405282460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristen M. Chevalier","raw_affiliation_strings":["Janssen Research & Development, LLC, Spring House, PA 19477"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development, LLC, Spring House, PA 19477","institution_ids":["https://openalex.org/I4405282460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002381779","display_name":"Steven W. Sutton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282460","display_name":"Janssen Research & Development (United States)","ror":"https://ror.org/05wae1a98","country_code":"US","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I4405282460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven W. Sutton","raw_affiliation_strings":["Janssen Research & Development, LLC, Spring House, PA 19477"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development, LLC, Spring House, PA 19477","institution_ids":["https://openalex.org/I4405282460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061791893","display_name":"Sui\u2010Po Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282460","display_name":"Janssen Research & Development (United States)","ror":"https://ror.org/05wae1a98","country_code":"US","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I4405282460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sui-Po Zhang","raw_affiliation_strings":["Janssen Research & Development, LLC, Spring House, PA 19477"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development, LLC, Spring House, PA 19477","institution_ids":["https://openalex.org/I4405282460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110172524","display_name":"Christopher M. Flores","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405282460","display_name":"Janssen Research & Development (United States)","ror":"https://ror.org/05wae1a98","country_code":"US","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I4405282460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher M. Flores","raw_affiliation_strings":["Janssen Research & Development, LLC, Spring House, PA 19477"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development, LLC, Spring House, PA 19477","institution_ids":["https://openalex.org/I4405282460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005538765","display_name":"Margery A. Connelly","orcid":"https://orcid.org/0000-0002-3917-592X","observed_orcids":["https://orcid.org/0000-0002-3917-592X"]},"institutions":[{"id":"https://openalex.org/I4405282460","display_name":"Janssen Research & Development (United States)","ror":"https://ror.org/05wae1a98","country_code":"US","type":"company","lineage":["https://openalex.org/I1330063522","https://openalex.org/I4405282460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margery A. Connelly","raw_affiliation_strings":["Janssen Research & Development, LLC, Spring House, PA 19477"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Janssen Research & Development, LLC, Spring House, PA 19477","institution_ids":["https://openalex.org/I4405282460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044773512","display_name":"Judith Storch","orcid":"https://orcid.org/0000-0001-5482-1777","observed_orcids":["https://orcid.org/0000-0001-5482-1777","https://orcid.org/0009-0003-8886-7476"]},"institutions":[{"id":"https://openalex.org/I102322142","display_name":"Rutgers, The State University of New Jersey","ror":"https://ror.org/05vt9qd57","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Judith Storch","raw_affiliation_strings":["Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901 Rutgers Center for Lipid Research, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ 08901","Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","Rutgers Center for Lipid Research, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ 08901"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901 Rutgers Center for Lipid Research, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Department of Nutritional Sciences Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]},{"raw_affiliation_string":"Rutgers Center for Lipid Research, School of Environmental and Biological Sciences, Rutgers University, New Brunswick, NJ 08901","institution_ids":["https://openalex.org/I102322142"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5044773512"],"corresponding_institution_ids":["https://openalex.org/I102322142"],"apc_list":{"value":3430,"currency":"USD","value_usd":3430},"apc_paid":{"value":3430,"currency":"USD","value_usd":3430},"fwci":2.6557,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.89384221,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"56","issue":"6","first_page":"1153","last_page":"1171"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.4871000051498413,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.4871000051498413,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13430","display_name":"Lipid metabolism and disorders","score":0.4336000084877014,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.014499999582767487,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/monoacylglycerol-lipase","display_name":"monoacylglycerol lipase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fat-absorption","display_name":"fat absorption","score":0.8230000138282776},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.8899999856948853},{"id":"https://openalex.org/keywords/diet-induced-obesity","display_name":"diet-induced obesity","score":0.996999979019165},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.968999981880188},{"id":"https://openalex.org/keywords/low-fat-diet","display_name":"low-fat diet","score":0.7319999933242798},{"id":"https://openalex.org/keywords/2-arachidonoylglycerol","display_name":"2-arachidonoylglycerol","score":0.8240000009536743},{"id":"https://openalex.org/keywords/endocannabinoid-degradation","display_name":"endocannabinoid degradation","score":0.7749999761581421},{"id":"https://openalex.org/keywords/circulating-lipids","display_name":"circulating lipids","score":0.6140000224113464},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.6150000095367432}],"concepts":[{"id":"https://openalex.org/C8051207","wikidata":"https://www.wikidata.org/wiki/Q4678003","display_name":"Monoacylglycerol lipase","level":4,"score":0.912714421749115},{"id":"https://openalex.org/C2491326","wikidata":"https://www.wikidata.org/wiki/Q5377024","display_name":"Energy homeostasis","level":3,"score":0.7625529170036316},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7021644115447998},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.678878128528595},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.6732069849967957},{"id":"https://openalex.org/C3018667095","wikidata":"https://www.wikidata.org/wiki/Q3455903","display_name":"Glucose homeostasis","level":4,"score":0.5645416378974915},{"id":"https://openalex.org/C40438245","wikidata":"https://www.wikidata.org/wiki/Q130964","display_name":"Calorie","level":2,"score":0.5348265171051025},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.5310231447219849},{"id":"https://openalex.org/C46721173","wikidata":"https://www.wikidata.org/wiki/Q368952","display_name":"Endocannabinoid system","level":3,"score":0.5290136337280273},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4724588394165039},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4265602231025696},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.4208296835422516},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3254120945930481},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.18564149737358093},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.14568284153938293},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.08163690567016602},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06467309594154358},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D004734","descriptor_name":"Energy Metabolism","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008994","descriptor_name":"Monoacylglycerol Lipases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008994","descriptor_name":"Monoacylglycerol Lipases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015430","descriptor_name":"Weight Gain","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050178","descriptor_name":"Monoglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063388","descriptor_name":"Endocannabinoids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1194/jlr.m058586","doi":"https://doi.org/10.1194/jlr.m058586","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.m058586","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5391054","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6399513","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4442873","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4442873","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Lipid Res","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6399513","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6399513","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Lipid Res","raw_type":"Text"},{"id":"pmid:25842377","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25842377","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of lipid research","raw_type":"Journal Article"},{"id":"pmid:30824679","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30824679","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of lipid research","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:b971bbc51aba493cb64a321bc494f40f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b971bbc51aba493cb64a321bc494f40f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Lipid Research, Vol 56, Iss 6, Pp 1153-1171 (2015)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1194/jlr.m058586","doi":"https://doi.org/10.1194/jlr.m058586","is_oa":true,"landing_page_url":"https://doi.org/10.1194/jlr.m058586","pdf_url":null,"source":{"id":"https://openalex.org/S11400418","display_name":"Journal of Lipid Research","issn_l":"0022-2275","issn":["0022-2275","1539-7262"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Lipid Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2198015830","display_name":null,"funder_award_id":"DK38389","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G9000901731","display_name":"Lipid transport in the intestine","funder_award_id":"R01DK038389","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":78,"referenced_works":["https://openalex.org/W1491109154","https://openalex.org/W1531695174","https://openalex.org/W1537738371","https://openalex.org/W1549092682","https://openalex.org/W1591647183","https://openalex.org/W1599716870","https://openalex.org/W1603736249","https://openalex.org/W1659973391","https://openalex.org/W1675830194","https://openalex.org/W1963482720","https://openalex.org/W1963739832","https://openalex.org/W1965033589","https://openalex.org/W1973818778","https://openalex.org/W1976269126","https://openalex.org/W1976904939","https://openalex.org/W1979165845","https://openalex.org/W1979755418","https://openalex.org/W1980659302","https://openalex.org/W1981147834","https://openalex.org/W1986435336","https://openalex.org/W1986487334","https://openalex.org/W1988006327","https://openalex.org/W2000054651","https://openalex.org/W2007064781","https://openalex.org/W2011180165","https://openalex.org/W2013878529","https://openalex.org/W2021728577","https://openalex.org/W2029471635","https://openalex.org/W2030734450","https://openalex.org/W2035768389","https://openalex.org/W2036412371","https://openalex.org/W2036992242","https://openalex.org/W2039481955","https://openalex.org/W2043446105","https://openalex.org/W2047878936","https://openalex.org/W2049342816","https://openalex.org/W2049772907","https://openalex.org/W2051554315","https://openalex.org/W2053141833","https://openalex.org/W2053196978","https://openalex.org/W2054750749","https://openalex.org/W2067913139","https://openalex.org/W2072168992","https://openalex.org/W2073734463","https://openalex.org/W2074142544","https://openalex.org/W2078898695","https://openalex.org/W2083897137","https://openalex.org/W2085407582","https://openalex.org/W2089714176","https://openalex.org/W2091315563","https://openalex.org/W2097173033","https://openalex.org/W2097494859","https://openalex.org/W2102671312","https://openalex.org/W2115351521","https://openalex.org/W2118505314","https://openalex.org/W2127624416","https://openalex.org/W2128635872","https://openalex.org/W2130768392","https://openalex.org/W2132380973","https://openalex.org/W2133811076","https://openalex.org/W2134812217","https://openalex.org/W2136423167","https://openalex.org/W2136608474","https://openalex.org/W2141753787","https://openalex.org/W2144657811","https://openalex.org/W2148981316","https://openalex.org/W2151449274","https://openalex.org/W2159267312","https://openalex.org/W2160234571","https://openalex.org/W2160499042","https://openalex.org/W2163953252","https://openalex.org/W2165708021","https://openalex.org/W2165780882","https://openalex.org/W2168526937","https://openalex.org/W2295701394","https://openalex.org/W2325961950","https://openalex.org/W2782519047","https://openalex.org/W4294216491"],"related_works":["https://openalex.org/W2085407582","https://openalex.org/W7145340015","https://openalex.org/W2261158911","https://openalex.org/W2942556914","https://openalex.org/W2074142544","https://openalex.org/W22340519","https://openalex.org/W3113124527","https://openalex.org/W2242912795","https://openalex.org/W2599234116","https://openalex.org/W7046455128"],"abstract_inverted_index":{"Monoacylglycerol":[0],"lipase":[1],"(MGL)":[2],"is":[3],"a":[4,57,64,173],"ubiquitously":[5],"expressed":[6],"enzyme":[7],"that":[8,163,171],"catalyzes":[9],"the":[10,26,34,37,44,79,92,128,160],"hydrolysis":[11],"of":[12,28,36,46,75,115,130],"monoacylglycerols":[13],"(MGs)":[14],"to":[15,22,168],"yield":[16],"FFAs":[17],"and":[18,31,111,138,176],"glycerol.":[19,40],"MGL":[20,165],"contributes":[21],"energy":[23,50,139],"homeostasis":[24,137],"through":[25],"mobilization":[27],"fat":[29,153],"stores":[30],"also":[32],"via":[33],"degradation":[35],"endocannabinoid":[38],"2-arachidonoyl":[39],"To":[41],"further":[42],"examine":[43],"role":[45],"MG":[47,76],"metabolism":[48],"in":[49,78,97,122,135],"homeostasis,":[51],"MGL(-/-)":[52,80,101,124,142],"mice":[53,81,86,102,107,143],"were":[54,87,103,120,127],"fed":[55],"either":[56],"10%":[58],"(kilocalories)":[59,66],"low-fat":[60],"diet":[61,68,99],"(LFD)":[62],"or":[63],"45%":[65],"high-fat":[67],"(HFD)":[69],"for":[70],"12":[71,93,113],"weeks.":[72],"Profound":[73],"increases":[74],"species":[77],"compared":[82],"with":[83],"WT":[84,106],"control":[85],"found.":[88],"Weight":[89],"gain":[90],"over":[91],"weeks":[94,114],"was":[95],"blunted":[96],"both":[98,109],"groups.":[100],"leaner":[104,174],"than":[105],"at":[108],"baseline":[110],"after":[112],"LFD":[116],"feeding.":[117],"Circulating":[118],"lipids":[119],"decreased":[121],"HFD-fed":[123],"mice,":[125],"as":[126],"levels":[129],"several":[131],"plasma":[132],"peptides":[133],"involved":[134],"glucose":[136],"balance.":[140],"Interestingly,":[141],"had":[144],"markedly":[145],"reduced":[146],"intestinal":[147],"TG":[148],"secretion":[149],"following":[150],"an":[151,177],"oral":[152],"challenge,":[154],"suggesting":[155],"delayed":[156],"lipid":[157],"absorption.":[158],"Overall,":[159],"results":[161],"indicate":[162],"global":[164],"deletion":[166],"leads":[167],"systemic":[169],"changes":[170],"produce":[172],"phenotype":[175],"improved":[178],"serum":[179],"metabolic":[180],"profile.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":12},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}