{"id":"https://openalex.org/W2394817781","doi":null,"title":"[Immunopathogenesis of chronic inflammatory diseases of the pharynx].","display_name":"[Immunopathogenesis of chronic inflammatory diseases of the pharynx].","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2394817781","mag":"2394817781","pmid":"https://pubmed.ncbi.nlm.nih.gov/23268242"},"language":"ru","primary_location":{"id":"pmid:23268242","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23268242","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vestnik otorinolaringologii","raw_type":"Comparative Study"},"parent_works":[],"lineage":["https://openalex.org/W2394817781"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091137786","display_name":"Liliya F. Aznabaeva","orcid":"https://orcid.org/0000-0002-8764-2334","observed_orcids":["https://orcid.org/0000-0002-8764-2334"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L F Aznabaeva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046203556","display_name":"\u041d. \u0410. \u0410\u0440\u0435\u0444\u044c\u0435\u0432\u0430","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N A Aref'eva","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5071428882","display_name":"A N Daianov","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A N Daianov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":"6","first_page":"27","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10984","display_name":"Sinusitis and nasal conditions","score":0.18729999661445618,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10984","display_name":"Sinusitis and nasal conditions","score":0.18729999661445618,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13770","display_name":"Pediatric health and respiratory diseases","score":0.18700000643730164,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":0.09030000120401382,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-laryngitis","display_name":"chronic laryngitis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/immunopathogenesis","display_name":"immunopathogenesis","score":0.9110000133514404},{"id":"https://openalex.org/keywords/epstein-barr-virus","display_name":"Epstein-Barr virus","score":0.906000018119812},{"id":"https://openalex.org/keywords/herpesviruses","display_name":"herpesvirus","score":0.7710000276565552},{"id":"https://openalex.org/keywords/staphylococcal-infections","display_name":"staphylococcal infections","score":0.8809999823570251},{"id":"https://openalex.org/keywords/streptococcal-infection","display_name":"streptococcal infection","score":1.0},{"id":"https://openalex.org/keywords/t-cell-mediated-immunity","display_name":"T cell immunity","score":0.949999988079071},{"id":"https://openalex.org/keywords/secretory-iga","display_name":"secretory IgA","score":0.8109999895095825},{"id":"https://openalex.org/keywords/ige","display_name":"IgE","score":0.8100000023841858},{"id":"https://openalex.org/keywords/igg","display_name":"IgG","score":0.9789999723434448}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8561053276062012},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.773186445236206},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.6924429535865784},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6079398393630981},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5962356925010681},{"id":"https://openalex.org/C2776752453","wikidata":"https://www.wikidata.org/wiki/Q174778","display_name":"Pharynx","level":2,"score":0.5272820591926575},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.4995718002319336},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.45191413164138794},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.42253559827804565},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.41736841201782227},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007113","descriptor_name":"Immunity, Innate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010612","descriptor_name":"Pharyngitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010614","descriptor_name":"Pharynx","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018928","descriptor_name":"Immunity, Mucosal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:23268242","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23268242","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vestnik otorinolaringologii","raw_type":"Comparative Study"},{"id":"mag:2394817781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23268242","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2279489219","https://openalex.org/W2327498133","https://openalex.org/W7133306569","https://openalex.org/W4235482360","https://openalex.org/W7140299817","https://openalex.org/W2444239480","https://openalex.org/W3084803593","https://openalex.org/W1763452055","https://openalex.org/W7216922749"],"abstract_inverted_index":{"The":[0,96,131],"objective":[1],"of":[2,13,44,53,66,71,98,105,118,141],"the":[3,14,51,64,67,72,85,103,112,116,121,125,138],"present":[4],"study":[5],"was":[6,48,61,81],"to":[7,83],"develop":[8],"indications":[9],"for":[10,50,137],"immunological":[11],"rehabilitation":[12],"patients":[15,37],"presenting":[16],"with":[17,38,57,91],"chronic":[18,45],"laryngitis.":[19,46],"Immunogenetic":[20],"characteristics":[21],"(including":[22,75],"both":[23],"local":[24],"and":[25,35,41,78,93,109,115,128],"systemic":[26],"immunity)":[27],"were":[28],"elucidated":[29],"in":[30,55,111,120],"54":[31],"practically":[32],"healthy":[33],"subjects":[34],"110":[36],"catarrhal,":[39],"hyperplastic,":[40],"atrophic":[42],"forms":[43],"PCR-diagnostics":[47],"performed":[49],"presence":[52],"herpes-viruses":[54],"conjunction":[56],"bacteriological":[58],"studies.":[59],"It":[60],"shown":[62],"that":[63],"efficacy":[65],"effector":[68],"protective":[69,133],"factors":[70],"immune":[73],"system":[74],"its":[76],"phagocytic":[77,126],"T-cell":[79],"components)":[80],"insufficient":[82],"suppress":[84],"persistent":[86],"Epstein-Barr":[87],"virus":[88],"infection":[89],"combined":[90],"staphylococcal":[92],"streptococcal":[94],"infections.":[95],"protection":[97],"laryngeal":[99],"mucosa":[100],"depended":[101],"on":[102],"involvement":[104],"proinflammatory":[106],"antibodies":[107],"(IgE":[108],"IgG)":[110],"inflammatory":[113],"process":[114],"severity":[117],"defects":[119],"elimination":[122],"mechanisms":[123],"(affecting":[124],"component":[127],"secretory":[129],"antibodies).":[130],"compromised":[132],"function":[134],"created":[135],"conditions":[136],"long-term":[139],"persistence":[140],"pathogens.":[142]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}