{"id":"https://openalex.org/W2394718577","doi":null,"title":"Anemia in ST-Elevation Myocardial Infarction Patients with Markers of Inadequate Bone Marrow Response.","display_name":"Anemia in ST-Elevation Myocardial Infarction Patients with Markers of Inadequate Bone Marrow Response.","publication_year":2015,"publication_date":"2015-08-01","ids":{"openalex":"https://openalex.org/W2394718577","mag":"2394718577","pmid":"https://pubmed.ncbi.nlm.nih.gov/26394493"},"language":"en","primary_location":{"id":"pmid:26394493","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26394493","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Israel Medical Association journal : IMAJ","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033818197","display_name":"Yaron Arbel","orcid":"https://orcid.org/0000-0003-4258-6313","observed_orcids":["https://orcid.org/0000-0003-4258-6313"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yaron Arbel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037930879","display_name":"Assi Milwidsky","orcid":"https://orcid.org/0000-0002-3319-0336","observed_orcids":["https://orcid.org/0000-0002-3319-0336"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Assi Milwidsky","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103685593","display_name":"Ariel Finkelstein","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ariel Finkelstein","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011519209","display_name":"Amir Halkin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amir Halkin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003789098","display_name":"Miri Revivo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miri Revivo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111732783","display_name":"Shlomo A. Berliner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shlomo Berliner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023965238","display_name":"Martin H. Ellis","orcid":"https://orcid.org/0000-0001-6804-1472","observed_orcids":["https://orcid.org/0000-0001-6804-1472"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin Ellis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110258136","display_name":"Itzhak Herz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Itzhak Herz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109285043","display_name":"Gad Keren","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gad Keren","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5085316875","display_name":"Shmuel Banai","orcid":"https://orcid.org/0000-0002-3299-2839","observed_orcids":["https://orcid.org/0000-0002-3299-2839"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shmuel Banai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2269,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.6534581,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"17","issue":"8","first_page":"500","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.5893999934196472,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.5893999934196472,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.12710000574588776,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11534","display_name":"Erythropoietin and Anemia Treatment","score":0.08749999850988388,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anemia","display_name":"anemia","score":0.9940000176429749},{"id":"https://openalex.org/keywords/st-elevation-myocardial-infarction","display_name":"ST-elevation myocardial infarction","score":1.0},{"id":"https://openalex.org/keywords/bone-marrow-response","display_name":"bone marrow response","score":0.9800000190734863},{"id":"https://openalex.org/keywords/reticulocyte-count","display_name":"reticulocyte count","score":0.9079999923706055},{"id":"https://openalex.org/keywords/reticulocyte-production-index","display_name":"reticulocyte production index","score":0.9739999771118164},{"id":"https://openalex.org/keywords/leukopenia","display_name":"leukopenia","score":0.6919999718666077},{"id":"https://openalex.org/keywords/thrombocytopenia","display_name":"thrombocytopenia","score":0.996999979019165},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5960000157356262},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9940000176429749},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":0.9890000224113464},{"id":"https://openalex.org/keywords/hemoglobin","display_name":"hemoglobin","score":0.8230000138282776},{"id":"https://openalex.org/keywords/primary-percutaneous-coronary-intervention","display_name":"primary percutaneous coronary intervention","score":0.8100000023841858},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.42399999499320984}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9667330980300903},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.687235951423645},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.6669595241546631},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.6129637360572815},{"id":"https://openalex.org/C68443243","wikidata":"https://www.wikidata.org/wiki/Q2786686","display_name":"Quartile","level":3,"score":0.606265127658844},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.5506630539894104},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.5121192932128906},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4935959577560425},{"id":"https://openalex.org/C2778488018","wikidata":"https://www.wikidata.org/wiki/Q42395","display_name":"White blood cell","level":2,"score":0.420126736164093},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3364188075065613},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.11408111453056335}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D000740","descriptor_name":"Anemia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001772","descriptor_name":"Blood Cell Count","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001853","descriptor_name":"Bone Marrow","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012042","descriptor_name":"Registries","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012156","descriptor_name":"Reticulocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D062645","descriptor_name":"Percutaneous Coronary Intervention","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:26394493","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26394493","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Israel Medical Association journal : IMAJ","raw_type":"Journal Article"},{"id":"mag:2394718577","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26394493","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:2487505093","doi":null,"is_oa":false,"landing_page_url":"https://www.ima.org.il/FilesUpload/IMAJ/0/164/82279.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W133554190","https://openalex.org/W1576231096","https://openalex.org/W1971972245","https://openalex.org/W1972706572","https://openalex.org/W1982106889","https://openalex.org/W1985854346","https://openalex.org/W1997802450","https://openalex.org/W2013263214","https://openalex.org/W2014485536","https://openalex.org/W2046540377","https://openalex.org/W2061903475","https://openalex.org/W2067744701","https://openalex.org/W2068866777","https://openalex.org/W2072607138","https://openalex.org/W2087214843","https://openalex.org/W2096151264","https://openalex.org/W2129941545","https://openalex.org/W2130307711","https://openalex.org/W2149745229","https://openalex.org/W2154783291","https://openalex.org/W2156502101","https://openalex.org/W2158431257","https://openalex.org/W2166950143"],"related_works":["https://openalex.org/W3175382793","https://openalex.org/W2536092944","https://openalex.org/W2411466901","https://openalex.org/W4407361355","https://openalex.org/W1485015382","https://openalex.org/W2739915931","https://openalex.org/W2321214416","https://openalex.org/W1973690753","https://openalex.org/W2035710757","https://openalex.org/W7218323461"],"abstract_inverted_index":{"BACKGROUND:":[0],"Anemia":[1],"confers":[2],"an":[3],"adverse":[4],"prognosis":[5],"in":[6,18,23,53,88,103,141,195,208,220],"patients":[7,194],"with":[8,61,119,149,193,211,232],"ST-elevation":[9],"myocardial":[10],"infarction":[11],"(STEMI).":[12],"Several":[13],"mechanisms":[14],"have":[15,234],"been":[16],"implicated":[17],"the":[19,31,42,89,109,131,142,196,221],"etiology":[20],"of":[21,33,44,71,116,124,145,214],"anemia":[22,128],"this":[24],"setting,":[25],"including":[26],"inflammation,":[27],"blood":[28,54,153],"loss,":[29],"and":[30,55,74,101,105,155,170,190,218,238],"presence":[32],"comorbidities":[34],"such":[35],"as":[36,48,241,243],"renal":[37],"failure.":[38],"OBJECTIVES:":[39],"To":[40],"evaluate":[41],"adequacy":[43],"bone":[45,257],"marrow":[46,258],"response":[47],"potentially":[49],"reflected":[50],"by":[51],"elevation":[52],"reticulocyte":[56,246],"counts.":[57],"METHODS:":[58],"Consecutive":[59],"men":[60,118,231],"STEMI":[62,120,233],"who":[63,75],"underwent":[64],"primary":[65],"percutaneous":[66],"intervention":[67],"within":[68],"6":[69],"hours":[70],"symptom":[72],"onset":[73],"presented":[76,148],"to":[77,98,130],"our":[78],"catheterization":[79],"laboratory":[80,106],"during":[81],"a":[82,212,244],"36":[83],"month":[84],"period":[85],"were":[86,111,121],"included":[87],"study.":[90],"The":[91],"cohort":[92],"was":[93,204],"divided":[94],"into":[95],"quartiles":[96],"according":[97,129],"hemoglobin":[99,146,198,223],"concentration,":[100],"differences":[102],"clinical":[104],"characteristics":[107],"between":[108],"groups":[110],"evaluated.":[112],"RESULTS:":[113],"A":[114],"total":[115],"258":[117],"recruited,":[122],"22%":[123],"whom":[125],"suffered":[126],"from":[127],"World":[132],"Health":[133],"Organization":[134],"classification":[135],"(hemoglobin":[136],"<":[137,168,181],"13":[138],"g/dl).":[139],"Men":[140],"lowest":[143],"quartile":[144],"concentration":[147,199],"significantly":[150,206],"lower":[151,236],"white":[152],"cell":[154],"platelet":[156,239],"counts":[157,240],"(9.6":[158],"\u00b1":[159,163,172,176],"2.9":[160],"vs.":[161,174],"12.6":[162],"3.6":[164],"x":[165,178],"103/\u03bcl,":[166,179],"P":[167,180],"0.001)":[169],"(231":[171],"79":[173],"263":[175],"8":[177],"0.01),":[182],"respectively,":[183],"despite":[184,248],"higher":[185,207,249],"inflammatory":[186,250],"biomarkers":[187],"(C-reactive":[188],"protein":[189],"fibrinogen)":[191],"compared":[192],"upper":[197],"quartile.":[200],"Reticulocyte":[201],"production":[202],"index":[203],"not":[205],"anemic":[209],"patients,":[210],"value":[213],"1.8,":[215],"1.4,":[216],"1.5":[217],"1.6":[219],"ascending":[222],"quartiles,":[224],"respectively":[225],"(P":[226],"=":[227],"0.292).":[228],"CONCLUSIONS:":[229],"Anemic":[230],"relatively":[235],"leukocyte":[237],"well":[242],"reduced":[245],"count":[247],"biomarkers.":[251],"These":[252],"findings":[253],"might":[254],"suggest":[255],"inadequate":[256],"response.":[259]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}