{"id":"https://openalex.org/W2394439739","doi":"https://doi.org/10.3760/cma.j.issn.1673-4157.2006.03.012","title":"The expression of human thyrotropin receptor and the detection of thyrotropin receptor antibody","display_name":"The expression of human thyrotropin receptor and the detection of thyrotropin receptor antibody","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2394439739","doi":"https://doi.org/10.3760/cma.j.issn.1673-4157.2006.03.012","mag":"2394439739"},"language":"en","primary_location":{"id":"mag:2394439739","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-GNFM200603013.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306514215","display_name":"Intern J Endocrinol Metab","issn_l":"1726-913X","issn":["1726-913X","1726-9148"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Endocrinology and Metabolism","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042625274","display_name":"Fang Pei-hu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802534033","display_name":"Tianjin Medical University General Hospital","ror":"https://ror.org/003sav965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802534033"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"\u738b\u5c11\u8273","raw_affiliation_strings":["300052,\u5929\u6d25\u533b\u79d1\u5927\u5b66\u603b\u533b\u9662\u4ee3\u8c22\u75c5\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"300052,\u5929\u6d25\u533b\u79d1\u5927\u5b66\u603b\u533b\u9662\u4ee3\u8c22\u75c5\u79d1","institution_ids":["https://openalex.org/I2802534033"]}]},{"author_position":"middle","author":{"id":null,"display_name":"\u51af\u51ed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802534033","display_name":"Tianjin Medical University General Hospital","ror":"https://ror.org/003sav965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802534033"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"\u51af\u51ed","raw_affiliation_strings":["300052,\u5929\u6d25\u533b\u79d1\u5927\u5b66\u603b\u533b\u9662\u4ee3\u8c22\u75c5\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"300052,\u5929\u6d25\u533b\u79d1\u5927\u5b66\u603b\u533b\u9662\u4ee3\u8c22\u75c5\u79d1","institution_ids":["https://openalex.org/I2802534033"]}]},{"author_position":"last","author":{"id":null,"display_name":"\u65b9\u4f69\u534e","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802534033","display_name":"Tianjin Medical University General Hospital","ror":"https://ror.org/003sav965","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802534033"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"\u65b9\u4f69\u534e","raw_affiliation_strings":["300052,\u5929\u6d25\u533b\u79d1\u5927\u5b66\u603b\u533b\u9662\u6838\u533b\u5b66\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"300052,\u5929\u6d25\u533b\u79d1\u5927\u5b66\u603b\u533b\u9662\u6838\u533b\u5b66\u79d1","institution_ids":["https://openalex.org/I2802534033"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042625274"],"corresponding_institution_ids":["https://openalex.org/I2802534033"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.35986094,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"26","issue":"03","first_page":"178","last_page":"180"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tsh-receptor","display_name":"TSH receptor","score":0.9869999885559082},{"id":"https://openalex.org/keywords/tsh-receptor-antibodies","display_name":"TSH receptor antibodies","score":0.8040000200271606},{"id":"https://openalex.org/keywords/autoimmune-thyroid-disease","display_name":"autoimmune thyroid disease","score":0.7480000257492065},{"id":"https://openalex.org/keywords/radioimmunoassay","display_name":"radioimmunoassay","score":0.8130000233650208},{"id":"https://openalex.org/keywords/bioassay","display_name":"bioassay","score":0.9810000061988831},{"id":"https://openalex.org/keywords/thyroid-stimulating-antibodies","display_name":"thyroid-stimulating antibodies","score":0.7519999742507935},{"id":"https://openalex.org/keywords/reporter-genes","display_name":"reporter genes","score":0.5049999952316284},{"id":"https://openalex.org/keywords/diagnosis-and-prognosis","display_name":"diagnosis and prognosis","score":0.527999997138977}],"concepts":[{"id":"https://openalex.org/C2777608072","wikidata":"https://www.wikidata.org/wiki/Q4862366","display_name":"Thyrotropin receptor","level":4,"score":0.9593968391418457},{"id":"https://openalex.org/C2778707442","wikidata":"https://www.wikidata.org/wiki/Q7831049","display_name":"Trab","level":4,"score":0.876991331577301},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6645828485488892},{"id":"https://openalex.org/C2776652619","wikidata":"https://www.wikidata.org/wiki/Q16483","display_name":"Graves' disease","level":3,"score":0.6247197389602661},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6235449910163879},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6097145676612854},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.524864912033081},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4684128165245056},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46618956327438354},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.40199360251426697},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3475531339645386},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.31634247303009033},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23014092445373535},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13700413703918457}],"mesh":[],"locations_count":2,"locations":[{"id":"mag:2394439739","doi":null,"is_oa":false,"landing_page_url":"http://en.cnki.com.cn/Article_en/CJFDTOTAL-GNFM200603013.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306514215","display_name":"Intern J Endocrinol Metab","issn_l":"1726-913X","issn":["1726-913X","1726-9148"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Endocrinology and Metabolism","raw_type":null},{"id":"mag:3030051035","doi":"https://doi.org/10.3760/cma.j.issn.1673-4157.2006.03.012","is_oa":false,"landing_page_url":"http://rs.yiigle.com/CN121383200603/228707.htm","pdf_url":null,"source":{"id":"https://openalex.org/S4306514215","display_name":"Intern J Endocrinol Metab","issn_l":"1726-913X","issn":["1726-913X","1726-9148"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Intern J Endocrinol Metab","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2039261487","https://openalex.org/W2065029233","https://openalex.org/W2140195025","https://openalex.org/W1833485294","https://openalex.org/W3004796381","https://openalex.org/W4309045290","https://openalex.org/W2329518780","https://openalex.org/W1848136262","https://openalex.org/W1995422268","https://openalex.org/W2137270698"],"abstract_inverted_index":{"Human":[0],"thyrotropin":[1],"receptor(TSHR)":[2],"is":[3],"an":[4,16],"important":[5,17],"antigen":[6],"of":[7,13,25,46,54,61,69],"autoimmune":[8],"thyroid":[9,77],"disease(AITD).":[10],"The":[11,67],"detection":[12,30],"TSHR":[14,63],"antibody(TRAb)play":[15],"role":[18],"in":[19],"the":[20,52,57],"diagnosis":[21],"and":[22,34,48,59,80],"prognosis":[23],"evalutaion":[24],"AITD.":[26],"At":[27],"present,":[28],"two":[29],"techniques,":[31],"radio-receptor":[32],"assay":[33],"bioassay,":[35],"are":[36,64],"usually":[37],"used":[38],"to":[39,75],"detect":[40],"TRAb.":[41],"Both":[42],"assays":[43],"need":[44],"plenty":[45],"high-purified":[47],"high-active":[49],"protein.":[50],"With":[51],"development":[53],"molecular":[55],"biology,":[56],"yield":[58],"activity":[60],"recombinant":[62],"improved":[65],"greatly.":[66],"use":[68],"report":[70],"gene":[71],"make":[72],"it":[73],"possible":[74],"distinguish":[76],"stimulating":[78],"antibody":[79],"TSH-binding":[81],"antibody.":[82]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}